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WO/2024/092967A1 |
The present invention relates to the technical field of enzyme engineering, and in particular, to a rare earth-dependent alcohol dehydrogenase mutant and use thereof. According to the present invention, a method combining the MutCompute ...
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WO/2024/096389A1 |
The present invention relates to a composition for preventing, ameliorating or treating cognitive dysfunction or Alzheimer's disease comprising, as an active ingredient, Lactobacillus fermentum SRK414 strain which has accession number KC...
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WO/2024/096511A1 |
The present application relates to an Aureobasidium pullulans CJFSKY2201 strain, deposited under accession number KCCM13230P; a culture fluid of the strain; a use of the strain for producing oligosaccharides; a composition including the ...
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WO/2024/097243A1 |
Disclosed herein are yeast strains and derivatives thereof, as well as compositions comprising the yeast strains for use in ethanol manufacture. The disclosure also relates to processes for producing ethanol from biomass using the yeast ...
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WO/2024/092330A1 |
The present invention relates to nucleotide sequences that encode new truncated chimeric insecticidal proteins that exhibit inhibitory activity on lepidopterans. Particular embodiments provide compositions and plants, parts of parts, and...
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WO/2024/096545A1 |
The present application relates to a microorganism producing purine nucleotides and a method for producing purine nucleotides using same.
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WO/2024/094002A1 |
The present invention relates to a fructose diphosphate optical probe. Specifically, provided in the present invention is a fructose diphosphate optical probe, which comprises a fructose-1,6-diphosphate sensitive polypeptide and an optic...
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WO/2024/095237A1 |
Provided is a method for large-scale production of magnetosomes, the method comprising maintaining in a fermentation vessel under continuous fermentation conditions a fermentation broth comprising magnetotactic bacteria for a duration of...
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WO/2024/091122A1 |
The invention is directed to a method for providing a foodstuff preservative. More specifically, to a foodstuff preservative that inhibits growth of Escherichia, Salmonella and/or Listeria. The invention is further directed to a foodstuf...
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WO/2024/092260A1 |
The present disclosure provides an isolated Glycomyces lithiumensis (ECO002) strain deposited at the Agricultural Research Service Culture Collection under the Accession number NRRL No. B-68190 according to the Budapest Treaty. The discl...
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WO/2024/087761A1 |
The present invention relates to a method for producing a polypeptide from a recombinant fusion protein, and disclosed are a method for producing a polypeptide by means of serially combining multiple protease cleavage sites and polypepti...
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WO/2024/088309A1 |
Provided are a multispecific antibody binding to GPRC5D and CD3 antigens, an antigen binding molecule thereof, a nucleic acid molecule encoding the multispecific antibody and the antigen binding molecule thereof, a vector containing the ...
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WO/2024/088435A1 |
Provided is a Pseudomonas sp. having a mutant of PHA polymerase PhaC61-3. The Pseudomonas sp. is fermented to produce a novel viscous polyhydroxyalkanoate, providing a new material for the preparation of degradable products.
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WO/2024/088396A1 |
Provided are an FNR mutant and the use thereof in gene expression regulation. The mutant has an R169G and/or a G216D mutation on the amino acid sequence of the FNR, and the amino acid sequence of the FNR is as shown in SEQ ID NO: 1, or h...
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WO/2024/090668A1 |
The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising as active ingredients a Bacillus velezensis JK1 strain deposited under the accession number KCTC 14627BP and a culture broth ther...
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WO/2024/089645A1 |
The present disclosure concerns a method of obtaining a composition having yeast proteins derived from yeast protoplasts The present disclosure also includes compositions comprising yeast proteins derived from yeast protoplasts, edible p...
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WO/2024/086963A1 |
Provided is a composition for use in preventing or minimizing exercise-induced muscle damage (EIMD) in a subject in need thereof. The composition includes Lactobacillus paracasei PS23 and a carrier thereof. Also provided is a method of p...
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WO/2024/089312A1 |
The present invention relates to a method for obtaining polycaprolactone (PCL) from polycaprolactam (nylon-6), wherein the method comprises: (a) depolymerising polycaprolactam (nylon-6) into monomeric caprolactam; (b) converting the mono...
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WO/2024/091804A1 |
Certain embodiments of the disclosure are related to, inter alia, mutant and/or modified Bacillus cells (strains) comprising enhanced protein productivity phenotypes, mutant and/or modified cells comprising enhanced/increased ilvE messen...
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WO/2024/088087A1 |
The present invention relates to the field of medical biology, and specifically to expression of a human papillomavirus (HPV) 68 L1 protein, and virus-like particles (VLPs) and a preparation method therefor. The amino acid sequence of th...
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WO/2024/085482A1 |
The present invention relates to a novel Metarhizium pinghaense 15R strain with insecticidal and bactericidal activity, and a use thereof. Specifically, the present invention relates to a novel Metarhizium pinghaense 15R strain that exhi...
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WO/2024/083954A1 |
A method of processing spent brewer's yeast (BSY) to a fermented BSY product is described. The BSY product is a pleasant tasting, nutritious and functional ingredient which enables the ingredient to be used for human consumption in foods...
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WO/2024/083600A1 |
In the present invention new Bacillus strains are provided. More specifically, Bacillus strains having extracellular hydrolase activity and demonstrating reduced malodor after incubation for at least 5 days for at least 25 °C in a lacto...
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WO/2024/082263A1 |
Provided are a system for controlling virus replication in response to a hypoxic environment and use thereof. The system comprises: a gene encoding an hypoxia response element, a gene encoding a virus transcription factor recognition ele...
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WO/2024/084510A1 |
The present invention relates to a cost-effective process for the synthesis of hyper-production of poly gamma glutamic acid using L-glutamic acid independent approach. Specifically, the present invention relates to the synthesis of poly ...
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WO/2024/083910A1 |
The present invention relates to a new bacterial strain and a new urolithin named urolithin G. The new strain of the invention is Enterocloster bolteae CEBAS S4A9 DSM 34392 and can customize urolithin production to mimic metabotype A and...
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WO/2024/084054A1 |
The present invention relates to a live attenuated Gram-negative bacterium comprising a modified hlyCABD operon, wherein the modified hlyCABD operon is split into a first segment and a second segment, each segment being operably linked t...
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WO/2024/084497A1 |
The present disclosure relates to manufacturing transferrin binding proteins. Specifically, the present disclosure relates to a simple, scalable, commercially viable fermentation and purification process for obtaining recombinant transfe...
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WO/2024/083973A1 |
The present invention relates to a host cell. The host cell finds utility as a biosensor by comprising at least one nucleic acid modification in the nucleic acid sequence of at least one gene. Also disclosed is the host cell for use as a...
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WO/2024/082327A1 |
A method for efficiently purifying phospholipid from coenzyme Q10 fermented powder, comprising the following steps: 1) mother liquor culture, 2) seed tank culture, 3) fermentation tank culture, 4) fermented liquor centrifugation, 5) high...
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WO/2024/082757A1 |
Provided are the use of chlorflavonin and derivatives thereof, in particular the use thereof in inhibiting the growth of microorganisms and inhibiting the growth of plants. Also provided are genes associated with the synthesis of flavone...
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WO/2024/082648A1 |
An intestinal typing detection system for predicting the curative effect of an immune preparation combined with platinum-containing dual-drug chemotherapy. By means of detecting the intestinal flora of a patient and analyzing abundance, ...
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WO/2024/085339A1 |
This method by which a computing device detects contamination of a culture medium may comprise the steps of: acquiring culture medium photography images; identifying one or more entities included in the culture medium photography images ...
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WO/2024/082262A1 |
Provided are a splicing system for controlling virus replication in response to a hypoxic environment, and a use thereof. The system comprises, mutually separated or fused to one another, a gene encoding an hypoxia sensing unit and a gen...
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WO/2024/085483A1 |
The present invention relates to a novel Beauveria bassiana 331R strain with insecticidal and bactericidal activity and use thereof and, in particular, to a novel Beauveria bassiana 331R strain (Accession No.: KACC83066BP) having control...
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WO/2024/083888A2 |
The present invention provides a method for producing polyhydroxyalkanoate (PHA) from polyester waste, the method comprising the steps of: (a) providing a culture broth comprising polyester waste; and (b) cultivating a microbe in the cul...
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WO/2024/085310A1 |
The present invention relates to a novel microbe that can decompose plastic and a plastic decomposition method using same. The microbe can decompose at least one plastic selected from the group consisting of PET, PVC, PS, PP and PE under...
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WO/2024/080441A1 |
The present invention provides: a Paracoccus aminovorans BM109 strain (accession number KCTC 15059BP), which is excellent for removing trimethylamine (TMA) or trimethylamine N-oxide (TMAO); and a pharmaceutical composition for preventing...
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WO/2024/079358A1 |
The present invention relates to a modified live attenuated Gram-negative bacteria, wherein said bacteria has been modified in such a way that RNA molecules can be safely and efficiently delivered to target eukaryotic cells. As such, the...
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WO/2024/078561A1 |
The present invention belongs to the technical fields of microorganisms and cosmetics, and particularly relates to a Bifidobacterium animalis strain and the use thereof. Experiments prove that a supernatant of a fermentation broth of the...
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WO/2024/077702A1 |
An alkaline protease mutant having an improved enzyme activity obtained by means of iterative saturation mutagenesis using overlapping PCR technology, and a preparation therefor and the use thereof. The alkaline protease gene apr from Ba...
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WO/2024/078463A1 |
Provided is a microbial system established based on a genetically modified bacterial strain under a genus of Pseudomonas with improved capacities to form more biofilms and trap more microplastics from a source than its wild-type form. In...
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WO/2024/078420A1 |
An isothermal nucleic acid amplification RAA primer probe combination for detecting Candida auris, and the use thereof. The primer probe combination has a high amplification efficiency, a strong specificity, and no obvious false positive...
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WO/2024/077406A1 |
The present invention relates to a biostimulant based on the bacterium Pseudomonas rhodesiae strain A20 RGM deposit 3341 for agricultural use in saline-boric environments. The product can be developed as solid and/or liquid formulations,...
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WO/2024/080626A1 |
Disclosed are: a Bacillus licheniformis JWS22003 strain (accession number: KACC 92452P) for promoting fermentation of by-products, auxin production, and plant growth; a method for promoting fermentation of by-products and plant growth by...
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WO/2024/078646A1 |
A method for preparing (R)-tebuconazole by means of an enzyme chemical process, comprising: firstly, by taking the whole cell of recombinant bacterium E. coli/Rpeh expressing an epoxide hydrolase as a catalyst, resolving a racemic tebuco...
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WO/2024/078368A1 |
A method for preparing a halogenated indole glucoside and Tyrian purple. The method comprises: a halogenation step, involving halogenating tryptophan to obtain halogenated tryptophan; and a glucoside preparation step, involving mixing th...
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WO/2024/077445A1 |
Provided are a 5'UTR element comprising a nucleotide sequence as shown in SEQ ID NO: 11 and the use thereof in the production of L-arginine. Further provided are a functional expression element containing the 5'UTR element and a promoter...
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WO/2024/077428A1 |
Provided is an enzyme with D-amino acid synthesis activity. The enzyme has an amino acid sequence as shown in SEQ ID NO: 10. Compared with an original strain before mutation, the enzyme has a higher catalytic activity for D-amino acid sy...
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WO/2024/074714A1 |
The present invention provides a method for increasing the growth efficiency in an anaerobic microbial fermentation of a microorganism capable of converting CO2, CO or a mixture thereof into at least one organic compound, the method comp...
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