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WO/2023/010789A1 |
A gRNA targeting a blaTEM drug-resistant gene and a drug-resistant plasmid carrying the blaTEM, a horizontally transferred gene knockout vector, and the use thereof in the reduction of the blaTEM drug-resistant plasmid. The provided gRNA...
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WO/2023/014048A1 |
The present invention relates to a novel microorganism, a lysate thereof, a culture medium, an extract of the culture medium, vesicles, and anti-inflammatory and/or antibacterial uses thereof. A novel strain and vesicles derived therefro...
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WO/2023/011576A1 |
Provided are a method for constructing a microorganism with a high yield of lactoyl-n-tetrasaccharide, and an application. A strain constructed in a previous stage for efficiently producing the precursor substance lactoyl-N-trisaccharide...
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WO/2023/011668A1 |
Disclosed in the present invention are a perinaphthenone compound and the use thereof. The compound can bind to E3 ubiquitin ligase tripartite motif 25 (TRIM25), thereby facilitating the recognition of TRIM25 to a pathogen and inducing p...
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WO/2023/014651A1 |
The present disclosure describes products formulated to inhibit respiratory conditions and symptoms in animals, along with associated methods of providing such products to the animals. Feeding methods involve providing animals with a fee...
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WO/2023/014054A1 |
The present invention relates to a novel microorganism, a lysate thereof, a culture medium, an extract of the culture medium, a vesicle, and anti-inflammatory and/or antibacterial uses thereof. A novel strain and a vesicle derived theref...
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WO/2023/010910A1 |
Provided are an organic selenium-enriched yeast, a preparation method therefor, a product, and an application. The organic selenium-enriched yeast is prepared by performing stage-by-stage expanded culture of a yeast strain, performing fe...
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WO/2023/012370A1 |
An artificial alkane oxidation system comprising components: a. an oxidase enzyme; and b. one or more enzymes to provide one or more alkanes. The artificial alkane oxidation system optionally has c. an electron transfer compound suitable...
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WO/2023/010820A1 |
Disclosed is a method for purifying indole-3-lactic acid from a lactobacillus plantarum fermentation supernatant, utilizing a fermentation supernatant of lactobacillus plantarum ZJ316 having a deposit number of CCTCC NO: M 208077, and co...
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WO/2023/006827A1 |
The invention relates to a method of making a product for human consumption which comprises partially lysed microalgae, said method comprising a) preparing a suspension of microalgae, wherein the microalgae belong to a phylaselected from...
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WO/2023/004770A1 |
Provided are a Pichia pastoris expression vector of fructosamine deglycase, a genetically engineered bacterium and a construction method therefor, and a protein expression method. The Pichia pastoris expression vector of fructosamine deg...
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WO/2023/004784A1 |
Provided are a recombinant CHO cell, a construction method therefor, a detection system containing same, and a detection method using same. The recombinant CHO cell stably expresses NGF on the surface thereof and can be used as a target ...
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WO/2023/006883A1 |
Provided herein are compositions and methods useful for producing thermophilic fermented dairy compositions, such as thermophilic fermented dairy products, having cream flavor. The compositions and methods provided herein include bacteri...
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WO/2023/004901A1 |
Provided are a group of GH10 family high-temperature-resistant xylanase mutants and the use thereof. By means of rational design, the GH10 family xylanase HwXyl10A gene cloned from fungus Hortaea werneckii is subjected to site-directed m...
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WO/2023/006885A1 |
Provided herein are compositions and methods for producing fermented plant-based compositions, e.g., fermented dairy alternative food products, having cream flavor. The compositions and methods provided herein include bacteria, e.g., Lac...
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WO/2023/004983A1 |
Provided are a strain of Leuconostoc citreum and the use thereof. The strain has the taxonomic name Leuconostoc citreum and a deposit number of CGMCC NO. 6431. The genome of the strain has two genes encoding levansucrases that are contin...
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WO/2023/006917A1 |
The present invention relates to microorganism compositions and fertilisers comprising them, which reduce soil nitrate accumulation and their use for avoiding nitrogen leaching.
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WO/2023/004969A1 |
Provided are an esterase mutant and the use thereof. The esterase mutant obtained by means of rational design and several rounds of evolution screening with enzymes on the basis of an amino acid sequence as shown in SEQ ID NO: 1 is chang...
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WO/2023/000612A1 |
Disclosed are a fungicide for botryodiplodia theobromae and the use thereof. Lysinibacillus boronitolerans or fermentation liquor thereof is prepared into the fungicide for botryodiplodia theobromae.
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WO/2023/000618A1 |
Provided are a Bacillus xiaoxiensis STB08 for producing a β-cyclodextrin glucosyltransferase, and a method for preparing the β-cyclodextrin glucosyltransferase by using the Bacillus xiaoxiensis STB08. Also provided is the β-cyclodextr...
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WO/2023/003175A1 |
The present invention relates to a novel Lactobacillus paracasei ATG-E1 strain (Accession No: KCTC 14245BP) and a composition comprising same for preventing or treating a respiratory disease, wherein the respiratory disease is induced by...
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WO/2023/004172A1 |
Provided are systems and methods for production of recombinant proteins in engineered microorganisms while reducing impurities produced in the culture.
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WO/2023/001633A1 |
The present invention relates to bacterial strains of Lactococcus lactis or Lactococcus cremoris, usable as starter cultures, able to provide both satisfactory rheological and organoleptic proper-ties, and satisfactory shelf life to a pl...
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WO/2023/000492A1 |
Provided in the present invention is a strain of Paenibacillus sp. for synthesizing an exopolysaccharide by means of fermenting wheat bran, and the deposit number of the strain is CGMCC NO. 8333; the exopolysaccharide synthesized has a w...
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WO/2023/288257A2 |
The present disclosure provides methods of producing substituted pyrazines. The methods comprise, in some embodiments, incubating a certain a-keto-acid, a certain aldehyde, and a pyruvate decarboxylase to form a certain a-hydroxyketone. ...
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WO/2023/284419A1 |
A pyruvate dehydrogenase mutant. On the basis of an amino acid sequence as shown in SEQ ID NO: 1, the 217th site of the sequence is mutated into any one of alanine, aspartic acid, glutamate, leucine and proline. The mutant can improve th...
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WO/2023/285480A1 |
The invention relates to a method for the lysis of yeast, in particular brewer's yeast, in order to isolate proteins and saccharides, comprising the following steps: a) providing a yeast suspension, in particular a brewer's yeast suspens...
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WO/2023/285738A2 |
The present invention relates to the fields of life sciences, micro-organisms and degradation of hydrocarbon chains such as polyolefins. Specifically, the invention relates to an isolated specific enzyme or a fragment thereof, wherein sa...
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WO/2023/283937A1 |
The present invention relates to a strain of Aspergillus oryzae (koji mold) ZA205 and to an application thereof. The Aspergillus oryzae ZA 205 simultaneously exhibits: (1) significantly increased glutaminase activity; (2) significantly i...
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WO/2023/285105A1 |
The present invention uses microfluidics droplets for studying the growth dynamics of communities of bacteria in the presence of various perturbations such as various chemicals or other microorganisms and to establish microbial assemblie...
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WO/2023/283821A1 |
Disclosed are a preparation method for and an application of lactic acid. The preparation method for lactic acid comprises the following steps: (1) inoculating a lactic acid-producing strain, after being activated, into a seed culture me...
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WO/2023/287025A1 |
The present invention relates to a deposited strain, a lysate thereof, a culture medium, an extract of the culture medium, and antibacterial uses thereof. A strain and a culture medium derived therefrom, according to an aspect of the pre...
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WO/2023/287205A1 |
The present invention relates to novel Leuconostoc citreum WiKim0129 isolated from kimchi and a composition comprising same. The Leuconostoc citreum WiKim0129 according to the present invention exhibits excellent anticancer effects and t...
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WO/2023/283681A1 |
Disclosed are therapeutic compositions comprising bacterial strains and methods for the treatment or prevention of disease. More particularly, disclosed are compositions comprising bacterial strains isolated from the human digestive trac...
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WO/2023/284853A1 |
The present invention provides Bacillus natto for producing menaquinone-7. Bacillus natto is deposited at the China General Microbiological Culture Collection Center, the accession number being CGMCC No. 21799. The strain has few require...
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WO/2023/286754A1 |
Provided is a composition which comprises ingredients that are easy to ingest on a daily basis and is effective in activating autophagy in intestinal epithelial cells or intestinal epithelial stem cells. Provided is an autophagy-activati...
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WO/2023/287313A1 |
The object of the invention is a method of obtaining a fortified mycelium of Fomitopsis officinalis, in which a small-scale pre-culture is carried out, in which the liquid medium according to Oddoux is inoculated with biomass derived fro...
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WO/2023/287202A1 |
The present invention relates to a novel Lactiplantibacillus paraplantarum WiKim0130 isolated from kimchi and a composition comprising same. The Lactiplantibacillus paraplantarum WiKim0130, according to the present invention, exhibits an...
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WO/2023/284069A1 |
The use of a bacterium in the preparation of a synergist of immune checkpoint inhibitors. By means of using a single-bacterium oral preparation of a human endogenous intestinal bacterium in combination with immune checkpoint inhibitors, ...
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WO/2023/284522A1 |
The present invention relates to the field of microorganisms, and specifically relates to a sulfamethoxazole-degrading pseudomonas silesiensis strain and an application thereof. The strain is preserved at the China Center for Type Cultur...
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WO/2023/284891A1 |
A low-temperature acid-resistant Saccharomyces cerevisiae. The Saccharomyces cerevisiae is classified and named as Saccharomyces cerevisiae DW, is preserved in the China General Microbiological Culture Collection Center, and the preserva...
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WO/2023/281787A1 |
The present invention is a method for using a lactic acid bacterium to produce spermidine, the bacterium releasing intracellularly produced spermidine to the outside of the cell.
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WO/2023/282622A1 |
The present invention relates to a composition comprising Lactobacillus sakei or extracellular vesicles derived therefrom. The present invention also relates to a novel Lactobacillus sakei LBML6 strain. The Lactobacillus sakei according ...
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WO/2023/279983A1 |
Provided are an antibacterial peptide P104 and a lyase LysP53 having broad-spectrum cracking activity, and applications thereof. An amino acid sequence of the antibacterial peptide P104 is as shown in SEQ ID NO.1, and a gene sequence of ...
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WO/2023/281335A1 |
The invention relates to particular species, strains, and compositions of lactic acid bacteria capable of increasing cellular levels of the hypoxia-inducible factor HIF-1α for the maintenance or enhancement of normoxia in hypoxia-induci...
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WO/2023/279565A1 |
Provided are a preparation method for an immobilized cell for tagatose production and a method for producing tagatose by using the immobilized cell. The preparation method for the immobilized cell comprises: mixing a fermentation broth o...
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WO/2023/279779A1 |
Provided is an application of a strain of Bacillus velezensis HL-5 for improving the rate of heparin extraction from aquatic products; the Bacillus velezensis HL-5 was preserved in Guangdong Microbial Culture Collection Center on 02 July...
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WO/2023/279687A1 |
A method for preparing immobilized cells for producing mannose, and a method using same for producing mannose, comprising: fermenting to separately obtain fermentation broths of Escherichia coli or Bacillus subtilis expressing α-glucan ...
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WO/2023/279585A1 |
Provided are a reporter system for screening VFM quorum sensing signal quenching bacteria and an inhibitor, and a construction method therefor. Dickeya zeae MS2 is used as a recipient bacterium, into which a reporter plasmid is transferr...
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WO/2023/279159A1 |
A process is described for producing polyhydroxyalkanoates from macroalgae, the process comprising the steps of: forming a macroalgal mixture from macroalgae and a liquid; hydrolysing the macroalgae mixture to form a macroalgal hydrolysa...
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