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WO/2024/007055A1 |
A method of producing modified bacteriophage ("phage") that are capable of infecting and causing lysis of a parent host bacteria that is insensitive to the unmodified phage is disclosed. The method comprises: treating a host bacteria ins...
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WO/2024/008597A1 |
The present invention relates to a fermentation product obtained by a fermentation process of at least one bacterial strain in the presence of at least one vegetable extract. The fermentation product of a bacterial may comprise alimentar...
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WO/2024/008046A1 |
A strain and a use thereof in the production of a β-nicotinamide mononucleotide (NMN). Disclosed is a strain of Escherichia coli, the accession number of the strain being CCTCC M2022922. Disclosed is a new strain for producing a β-NMN,...
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WO/2024/008205A1 |
The present invention belongs to the technical fields of genetic engineering and enzyme engineering, and specifically relates to the use of MmBBK2 in the preparation of trypsin and chymotrypsin inhibitors. The MmBBK2 has an amino acid se...
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WO/2024/007940A1 |
A method for producing a target product from biomass waste, comprising the following steps: (A) putting bacteria A into a first culture medium made from biomass waste and performing degrading fermentation, the bacteria A being organic ma...
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WO/2024/007053A1 |
The present invention relates to bacterial strains and compositions, and their use for controlling diseases in plants and for promoting plant growth. In one aspect, the isolated bacterial strain RR15 of the genus Pantoea, deposited under...
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WO/2024/008896A1 |
The present invention relates to an engineered unicellular Stramenopile microalga comprising a loss of function of the homologous Seipin gene, an in vitro method of producing triacylglycerols (TAG), and uses thereof.
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WO/2024/002335A1 |
Provided is a live bacteria strain of a species from Pseudomonas sp. such as Pseudomonas aeruginosa and uses thereof. More particularly, provided is a live bacteria strain of P.aeruginosa with reduced OprF activity, to a vaccine against ...
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WO/2024/000364A1 |
The present invention relates to the technical field of gene engineering and mutagenesis, and provides a corynebacterium glutamicum (C. glutamicum) efficient mutant, a recombinant bacterium construction method and a use. A highly conserv...
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WO/2024/003493A1 |
The present invention relates to the genetic modification of bacteria in the genus Clostridium, typically solvent-producing bacteria in the genus Clostridium. The invention further relates to methods, tools and kits for deleting or modif...
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WO/2024/005573A1 |
The present invention relates to a Bifidobacterium breve JKL2022 strain capable of mass-producing natural conjugated linoleic acid (CLA), and a method for mass-producing conjugated linoleic acid using the same. The method of the present ...
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WO/2024/004138A1 |
Provided is a beverage that contains Lacticaseibacillus paracasei bacteria and non-milkfat solid matter, wherein the non-milkfat solid matter constitutes less than 8.0 mass% of the total mass of the beverage.
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WO/2024/000368A1 |
The present invention relates to the technical field of genetic engineering, and provides recombinant Escherichia coli and a construction method therefor, and a method for synthesizing 1,5-pentanediamine. The recombinant Escherichia coli...
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WO/2024/001184A1 |
A mutant of phytase APPAmut4 is provided. Compared with parents, the mutant has enhanced phytase thermostability, and an optimal mutant APPAmut9 can still retain about 70% of activity after being treated at 100 ℃ for 5 min. The provide...
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WO/2024/005443A1 |
The present invention relates to a novel Micrococcus flavus strain, a lysate thereof, a culture thereof, an extract from the culture, and uses thereof for improving skin condition. The strain has a skin condition-improving effect, and th...
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WO/2024/006888A1 |
Aspects of the disclosure relate to genetic modifications which increase heterologous protein production in a host cell, such as a methylotrophic yeast host cell, such as Pichia pastoris. Such genetic modifications may comprise, in some ...
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WO/2024/005625A1 |
The present invention relates to a novel fermentation process using a particular strain of Kluyveromyces marxianus, referred to as KMPROTEO 1, to obtain a single-cell protein useful in the food industry. In the present description, the i...
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WO/2024/001593A1 |
Provided is an engineered ketoreductase polypeptide capable of preparing chiral alcohols, especially for catalyzing the reduction of ethyl 4-chloroacetoacetate to produce ethyl (R) -4-chloro-3-hydroxybutyrate. The polypeptides has high c...
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WO/2024/001838A1 |
Provided are a symbiotic bacterium in humans for promoting hair growth and use thereof. Specifically, provided is use of Staphylococcus hominis in treating alopecia or promoting hair growth, skin repair and regeneration and the like. Als...
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WO/2024/004139A1 |
Provided is fermented milk that contains Lacticaseibacillus paracasei bacteria and milk fat, wherein the milk fat constitutes at most 2.0 mass% of the total mass of the fermented milk.
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WO/2024/000237A1 |
Disclosed in the present invention is the use of IAA-PO1 gene in inducing primordium formation of Pleurotus ostreatus and resisting stress during the growth and development of Pleurotus ostreatus, which use belongs to the technical field...
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WO/2024/001845A1 |
The present invention provides a preparation method and use of a defective filovirus. Specifically, the present invention provides a defective recombinant filovirus, a coding sequence of one or more key viral proteins in a genome of the ...
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WO/2023/247483A1 |
The present invention relates to a mixture of human milk oligosaccharides ("HMOs") comprising five fucosylated HMOs, as well as to an enzymatic process for making said mixture, wherein said synthesis comprises an α1-3/4-transfucosidase ...
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WO/2023/249498A1 |
Disclosed are methods of epigenetic modification of microbes, including yeast and yeast starter cultures for use in fermentation of food products. The methods comprise contacting the microbe, yeast or yeast starter culture with an epigen...
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WO/2023/245259A1 |
The present invention relates to plant growth promoting endophytes, preferably of plants of the Glycine genus, particularly plant growth promoting Curtobacterium sp. endophytes. The present invention also relates to seeds, plants, and pa...
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WO/2023/248144A1 |
This invention relates to use of a strain of probiotic bacteria or derivatives thereof for increasing feed efficiency, enhancing growth and/or productivity, improving body weight or body composition, and/or increasing milk production in ...
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WO/2023/246621A1 |
A coxsackievirus A10 strain and a use thereof. Amino acid sequences of VP4, VP3, VP2 and VP1 proteins of the coxsackievirus A10 strain are respectively as represented by SEQ ID NOs 1, 2, 3 and 4, and amino acid sequences of 2A, 2B, 2C, 3...
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WO/2023/246131A1 |
The present invention provides a double-core-shell loaded microbial material as well as a preparation method therefor and the use thereof. The double-core-shell loaded microbial material is used for mineralizing heavy metals in polluted ...
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WO/2023/245955A1 |
The present invention discloses an apparatus and method for nucleic acid detection. The apparatus comprises a substrate capable of rotating during nucleic acid detection. The interior of the substrate comprises the following chambers: a ...
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WO/2023/245933A1 |
Disclosed herein are a method for efficiently producing L-homophenylalanine and a strain for producing L-homophenylalanine. According to the present invention, a new pathway for synthesizing L-homophenylalanine via enzymatic cascade reac...
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WO/2023/246674A1 |
Provided is a Bifidobacterium bifidum strain ibiome001, which can significantly reduce the weight and white fat mass of high-fat feed-induced obese and diabetic mice, and improve the expression of lipolytic genes ATGL and HSL. The fastin...
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WO/2023/248690A1 |
The present disclosure provides an agent for inducing plant disease resistance, the agent being capable of effectively inducing resistance to disease in plants. An agent for inducing plant disease resistance according to the present disc...
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WO/2023/247577A1 |
The present invention relates to the use of human milk oligosaccharides (HMOs) for improving the regeneration and/or viability of Lactobacillus bacteria in acidic environments. HMOs were found to increase the number of viable Lactobacill...
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WO/2023/245240A1 |
Provided herein is a method of promoting sexual maturity in a collection of aquatic animals comprising feeding the animals recombinant algae that express a gonad stimulating hormone that promotes sexual maturity. Further disclosed is met...
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WO/2023/247514A1 |
The present invention relates to nucleic acid constructs comprising a first polynucleotide encoding a signal peptide from a bacterial galactanase and a second polynucleotide encoding a polypeptide having mannanase activity; expression ve...
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WO/2023/247578A1 |
The present invention relates to the use of human milk oligosaccharides (HMOs) for improving the regeneration and/or viability of Bifidobacteria in acidic environments. HMOs were found to increase the number of viable Bifidobacteria upon...
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WO/2023/250454A1 |
A method for excluding an aggressive incompatibility (AI) trait from Agaricus bisporus mushroom strains, wherein the method includes mating a culture of a hybrid mushroom line designated B18287-s82, a representative culture of the line h...
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WO/2023/244843A1 |
The present disclosure relates to the methods and compositions for enhancing productivity or yield in fermentation. The methods include culturing host cells at a high pH to increase oxygen uptake as well as a higher yield and productivit...
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WO/2023/243924A1 |
The present invention relates to a novel Micrococcus terreus strain, a disrupted solution thereof, a culture medium, an extract of the culture medium, and a use thereof for improving skin condition. The strain has a skin condition-improv...
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WO/2023/240794A1 |
The present invention relates to recombinant Escherichia coli for producing L-homoserine and the use thereof. L-homoserine synthesis related genes in Escherichia coli are modified on a genome level by means of metabolic engineering; and ...
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WO/2023/243624A1 |
The present invention provides a plastic fluid composition comprising: (1) a microorganism; and (2) a polysaccharide or nanofibers made of the polysaccharide, wherein when the microorganism is a bacteria, the microorganism is contained...
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WO/2023/240871A1 |
Provided are a glutamate decarboxylase mutant and the use in the production of γ-aminobutyric acid. Further provided are an improved recombinant Corynebacterium glutamicum and a biosensor capable of responding to γ-aminobutyric acid.
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WO/2023/240607A1 |
Provided is a gene editing method for the genome of bacteria capable of producing bacterial cellulose. The method comprises the following steps: S1) determining a target gene or site to be modified in bacteria capable of producing cellul...
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WO/2023/240678A1 |
Disclosed are a polyketone compound with an anti-inflammatory activity, and a preparation method therefor and the use thereof. The method comprises: isolating Penicillium endophytic fungus (Penicillium sp.) HJT-A-10 from a root slice col...
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WO/2023/240679A1 |
The present invention relates to the technical field of medicines, and disclosed are a pair of polyketide compounds having anti-inflammatory activity, a preparation method therefor, and a use thereof. Specifically, endophytic fungus Alte...
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WO/2023/240910A1 |
Bacillus halotolerans BJ-3 and an application thereof, the Bacillus halotolerans BJ-3 having a preservation number CGMCC No. 24115. Said strain of Bacillus halotolerans exhibits bacterial inhibition activity with regard to phytopathogeni...
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WO/2023/239145A1 |
The present application relates to: a microorganism deposited under accession number KCCM12835P; a method for producing riboflavin using the microorganism; a composition for producing riboflavin, the composition comprising the microorgan...
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WO/2023/236452A1 |
Provided is use of a Lactobacillus paracasei culture in preparing a medicament for preventing and treating oral ulcer. The Lactobacillus paracasei culture comprises Lactobacillus paracasei ET-22 cells and/or extracellular metabolites the...
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WO/2023/236638A1 |
Provided are a thermal stability-improved glucose oxidase GoxM10 mutant, a derivative mutant thereof, and use thereof in the feed industry.
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WO/2023/236797A1 |
Disclosed in the present invention are a hangtaimycin derivative, a preparation method therefor, and the use thereof. The hangtaimycin derivative is prepared by performing fermentation in an SFMR culture medium by using Streptomyces spec...
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