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JP3756538B2 |
PURPOSE: To obtain a new ergosterol analog, having suppressing actions on the seed formation of plants and useful as a suppressant, etc., for the seed formation of the plants useful as a nontoxic herbicide by extracting the analog from a...
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JP2006507369A |
The present invention provides 5-androsten-3beta-ol steroid intermediates and processes for their preparation.
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JP3742435B2 |
A method for preparing at least one hydroxycholesterol chosen from the group consisting of 25-hydroxycholesterol, 17, 25-dihydroxycholesterol and 25, 26-dihydroxycholesterol by biological hydroxylation of cholesterol, and the aforementio...
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JP2005526860A |
The steroidogenic acute regulatory protein (StAR), a mitochondrial protein required for stress responses, reproduction, and sexual differentiation of male fetuses is shown to exert its activity transiently at the outer mitochondrial memb...
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JP2005523927A |
The present invention relates to improved methods for synthesising cyproterone acetate (17 alpha -Acetoxy-6-chloro-1 alpha , 2 alpha -methylene-4,6-pregnadiene-3,20-dione) from solasodine. The methods of the invention are shorter as thos...
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JP3679805B2 |
There is provided a cholesterol oxidase having the following physico-chemical properties: a) Enzymatic activity: catalyses the reaction: cholesterol + O2 -> 5-cholesten-3-one + H2O2; b) Substrate specificity: specific to 3 beta -choleste...
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JP3678362B2 |
To provide a fermented carrot containing at least one among a saponin decomposed products, namely 20S-protopanaxadiol-20-O-β-D-glucopyranoside, 20S-protopanaxadiol and 20S-protopanaxatriol by decomposing a saponin component contained in...
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JP2005517443A |
The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499-1695 of SEQ ID NO:1 or by nucleotides 387-142...
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JP3656875B2 |
To obtain a new cycloergostance derivative exhibiting an antifungal activity against pathogenic fungi and useful as a medicine, an agrochemical or a raw material for converting into the medicine, the agrochemical, etc., by culturing a mi...
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JP2005137201A |
To provide a method for producing soyasapogenol B, by which the soyasapogenol B useful as a medicine or a raw material for medicines can newly be produced from sophoradiol (12-oleanene-3,22-diol).This method for producing soyasapogenol B...
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JP2005130778A |
To provide a method for readily producing an oleanane-type triterpene by utilizing a cultured cell of a plant belonging to the genus Melianthus.This method for producing the oleanane-type triterpene comprises culturing the cultured cell ...
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JP2005512502A |
The present invention relates to a novel cytochrome P450-like enzyme (Aspergillus ochraceus 11 alpha hydroxylase) and an oxidoreductase (Aspergillus ochraceus oxidoreductase) isolated from cDNA library generated from the mRNA of Aspergil...
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JP3643082B2 |
To obtain a new Saccharothrix strain which can produce pravastatin from compactin in a high yield with high conversion efficiency and at a low epipravastatin rate, and to provide an isolation method by which an (HMG)-CoA reductase inhibi...
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JP2005052009A |
To produce a tirucalla-7,24-dien-3β-ol synthase, a DNA encoding the enzyme and tirucalla-7,24-dien-3β-ol and/or various kinds of terpenoids biosynthesized from the tirucalla-7,24-dien-3β-ol by using a cell in which a DNA encoding the ...
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JP2005021106A |
To provide a method for efficiently obtaining a drug metabolite by which the produced drug metabolite can be efficiently collected.This method for producing the drug metabolite by a microorganism having drug-metabolizing ability, and obt...
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JP2005021104A |
To efficiently produce a drug metabolite by a microorganism having a drug-metabolizing ability.This method for producing the drug metabolite by the microorganism having the drug-metabolizing ability comprises the following steps (1) and ...
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JP2004337165A |
To provide a technology applicable for amelioration of state of the skin (prevention and amelioration of dry rough skin, prophylaxis, prevention, of melasma, wrinkle, etc.) or treatment of hyperlipidemia, etc., by developing a technology...
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JP3594623B2 |
PURPOSE: To increase the sterol accumulation in a plant by increasing the copy number of a structural gene coding for a polypeptide having a hydroxymethylglutaryl-CoA (HMG-CoA) reductase activity. CONSTITUTION: A plant is transformed wit...
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JP2004535805A |
The present invention is a novel process for the transformation of 17alpha-hydroxy-6alpha-methylpregn-4-ene-3,20-dione 17-acetate (I)to 11beta,17alpha,21-trihydroxy-6alpha-methylpregna-1,4-diene-3
,20-dione 21-acetate (VI)
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JP2004321114A |
To provide a method for producing a valuable substance by using a microorganism having improved NADH supplying potential.A microorganism having no or lowered deoxycytidine triphosphate deaminase activity compared with wild-type strain an...
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JP3589685B2 |
PURPOSE: To efficiently obtain 25-hydroxystroids useful as medicines, etc., in high yield in one stage by adding steroids to a specific microbial cell, etc., of an actinomyces and converting the hydrogen atom at the 25-position into hydr...
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JP2004532014A |
The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in me...
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JP2004524858A |
Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly,...
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JP3547163B2 |
PURPOSE: To prepare a culture medium which enables mammalian cells to grow and induce differentiation without use of serum and to provide a method for producing a substance through mammalian cell culture using the medium. CONSTITUTION: T...
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JP2004141125A |
To provide a method for efficiently producing sterols such as zymosterol, cholesta-7,24-dien-3Δ-ol or biosynthetic compound derived therefrom.Sterols are separated from a cultured product produced by culturing Eumycetes (yeast or fungi)...
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JP2004512805A |
A process for producing nitrosonium ions is described, in which a nitroxyl compound such as TEMPO is oxidized using an oxidizing agent in the presence of a complex of a transition metal such as Mn, Fe, Cu, and a complexing agent such as ...
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JP2004057154A |
To produce dammarenediol II synthase by cloning a DNA encoding dammarenediol II synthase and produce various terpenoids produced from dammarenediol II by biosynthesis.A kind of oxide squalene ring-closing enzyme cDNA is cloned from an mR...
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JP2004057159A |
To produce taraxerol synthase by cloning a DNA encoding taraxerol synthase and to produce various kinds of terpenoids produced from taraxerol by biosynthesis.A kind of oxide squalene ring-closing enzyme cDNA is cloned from an mRNA prepar...
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JPWO2002006491A1 |
An object of the present invention is to obtain a novel isopentenyl diphosphate isomerase and a gene encoding it. According to the present invention, an enzyme protein having isopentenyl diphosphate isomerase activity having the followin...
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JP2004500340A |
The invention concerns a novel method for producing hydroxylated and/or acetylated steroid comprising steps which consist in: culturing yeasts on a medium comprising at least a precursor of such hydroxylated and/or acetylated steroids; t...
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JP2003529366A |
The invention relates to a process for the selective alcoholysis of a free sterol, by contacting said free sterol with a fat-based product, optionally with the addition of carboxylic fatty acid(s) and/or ester derivative(s) thereof that ...
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JP2003135091A |
To provide a transesterification process that can esterify not only sterols but also stanols, particularly a method of producing esters that is suitable for the use as functional foods.Steryl or stanyl esters are produced by (a) bringing...
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JP2003079390A |
To provide a method for transforming a fatty acid sterol ester which has not been effectively used to free sterol and recover the sterol.This method for producing sterol includes a process to transform the fatty acid sterol ester to free...
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JP2003079391A |
To provide a method of selective transesterification of stanols in a mixture containing sterols and the stanols and a method of separation of the sterols from the mixture.The method of esterification produces a reaction mixture by bringi...
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JP2003061671A |
To clone a testosterone metabolic pathway system enzyme gene in C. testosteroni TA441 strain, to produce the gene-broken strain, and to analyze its structure.The testosterone metabolic pathway system enzyme gene is cloned, and its struct...
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JP2003024096A |
To provide a method for producing a sterol fatty acid ester which is inexpensive as a material for foods, is safe for human bodies, and is functionally excellent.In processes (112 to 116) for treating a raw material (110) comprising a st...
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JP3358812B2 |
A method is provided for isolating 5,7-diene-containing steroids, particularly 3 beta -ols and esters of 3 beta -ols, from a sterol mixture. The method involves (1) treating the mixture with a dienophile or with an oxidizable dienophile ...
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JP2002537374A |
A process for producing nitrosonium ions is described, in which a nitroxyl compound such as TEMPO is oxidized using an oxidizing agent in the presence of a complex of a transition metal such as Mn, Fe, Cu, and a complexing agent such as ...
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JP2002233396A |
To provide a method for producing sterol fatty acid esters, obtained from a deodorized scum oil by a synthesizing reaction using an enzyme in supercritical carbon dioxide, by which the sterol fatty acid esters having an excellent quality...
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JP2002153296A |
To provide a method for enzymatically producing an inexpensive and highly safe sterol fatty acid ester for foods usable as a general food material, health food material or pharmaceutical material and having high functional quality includ...
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JP3283551B2 |
PURPOSE: To increase the accumulation of sterols, by raising the expression level of a structural gene encoding a polypeptide having HMG-CoA reductase activity in a specific yeast. CONSTITUTION: A yeast of the genus Saccharomyces is sele...
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JP3237722B2 |
PURPOSE: To provide new antibiotic substances Mer-NF8054A and X useful as an antimycotic agent and producible by culturing a microbial strain belonging to the genus Aspergillus and capable of producing the antibiotic substance Mer-NF8054...
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JP3231901B2 |
PURPOSE: To obtain the subject compd. having progestational activity and antiesterogenic activity by a new method using a specified compd. as the starting material. CONSTITUTION: First, a compd. expressed by formula I (R1 is a 1-3C alkyl...
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JP2001518301A |
The invention relates to a method for producing ergosterol and intermediate products thereof by means of recombinant yeasts and plasmids for transforming yeasts.
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JP3219317B2 |
PURPOSE: To efficiently produce the brassino steroid-like substance in a high yield. CONSTITUTION: This method for producing the brassino steroid-like substance is characterized by culturing a photo-synthetic bacterium and subsequently i...
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JP2001211891A |
To produce a novel nucleic acid originated from Tetrahymena coding for a triterpenoid cyclase.This nucleic acid is originated from Tetrahymena for coding a triterpenoid cyclase specific to Trichinella spiralis. The nucleotide sequence ac...
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JP3192410B1 |
[wrap up] [Task] Used as a general food material, health food material, or pharmaceutical material in the processing conditions, synthetic reaction conditions, and subsequent purification processes of raw materials for producing highly s...
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JP3192411B1 |
[wrap up] [Task] The present invention relates to general food materials, health food materials, or general food materials or health food materials in the processing conditions, synthetic reaction conditions, and subsequent purification ...
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JP2001509792A |
Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula Iwherein-A-A- represents the group -CHR4-CHR5- or -CR4=CR5-;R3, R4 and R5 are in...
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JP2001136996A |
To provide a microbiological production process for ursodeoxycholic ester. A microorganism capable of producing 7β-hydroxy-steroid dehydrogenase is attached or immobilized onto the surfaces of a hydrophilic immobilized carrier that is c...
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