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WO/2022/174177A1 |
The present disclosure relates to engineered microbial host cells comprising exogenous genes coding for proteins responsible for converting histidine and cysteine into ergothioneine in greater efficiency than the wild-type cells. Also pr...
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WO/2022/166838A1 |
Provided is a transaminase mutant, having a sequence on which an amino acid mutation takes place on the basis of the sequence as represented by SEQ ID NO: 13. Provided is an enatioselective flipped ω-transaminase ATA-117 mutant. The ami...
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WO/2022/166104A1 |
Provided is a method for synthesizing a chiral amine compound. An amino reaction is performed on a ketone substrate by means of a transaminase under the action of an amino donor, and the chiral amine compound is obtained. A conserved ami...
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WO/2022/167135A1 |
The present invention relates generally to the field of plant-based food. In particular, the present invention relates to improving the amino acid profile of plant-based food products. One embodiment of the present invention relates to t...
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WO/2022/166103A1 |
Provided are a transaminase mutant and an application thereof. The transaminase mutant is obtained by mutating one or more amino acids in SEQ ID NO: 2 or is a mutant obtained by taking the sequence SEQ ID NO: 1 of wild-type CVTA transami...
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WO/2022/168952A1 |
The present invention provides: an enzyme that transfers a prenyl group to an arginine residue or an arginine analog residue in a peptide, or to arginine or an arginine analog, wherein the enzyme includes an amino acid sequence represent...
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WO/2022/163920A1 |
The present application relates to a novel cysteine sulfinate desulfinase variant, Corynebacterium stationis strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163940A1 |
The present application relates to a novel galactoside O-acetyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163923A1 |
The present application relates to a novel ATP phosphoribosyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163912A1 |
The present application relates to a type II citrate synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163922A1 |
The present application relates to a novel asparagine synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163910A1 |
The present application relates to a malate dehydrogenase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163917A1 |
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163934A1 |
The present application relates to a novel D-alanine—D-alanine ligase A variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163981A1 |
The present application relates to a phospho-2-dehydro-3-deoxyheptonate (aroG) aldolase variant, a microorganism comprising same, and a method for producing an amino acid by using same.
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WO/2022/163921A1 |
The present application relates to a novel spermidine synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163937A1 |
The present application relates to a novel ABC transporter ATP-binding protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163909A1 |
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/164890A2 |
Probiotic bacteria are genetically modified to produce and excrete enhanced levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Exemplary probiotic bacteria include Lactococcus lactis (L. lactis). The genetically mo...
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WO/2022/163915A1 |
The present application relates to a Co/Zn/Cd efflux system component variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163938A1 |
The present application relates to a novel ribonuclease P variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163911A1 |
The present application relates to a primosome assembly protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163939A1 |
The present application relates to a novel MFS transporter variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/161914A1 |
The present invention relates to high temperature fermentation of fine chemicals, in particular L-proline and intermediates of L-proline synthesis, and to microorganisms for such fermentation processes. The invention further relates to g...
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WO/2022/163951A1 |
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163941A1 |
The present application relates to a novel spermidine synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163928A1 |
The present application relates to a novel cyanate transporter family protein variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/163918A1 |
The present application relates to a novel tetrahydrodipicolinate N-succinyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163925A1 |
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163919A1 |
The present application relates to a novel urease accessory protein variant, Corynebacterium stationis strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163916A1 |
The present application relates to a 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP) synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163935A1 |
The present application relates to a novel glucosamine-6-phosphate deaminase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163913A1 |
The present application relates to a membrane protein TerC variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163904A1 |
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163914A1 |
The present application relates to a mycothione reductase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/163924A1 |
The present application relates to a novel 5,10-methylenetetrahydrofolate reductase variant, Corynebacterium stationis strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163933A1 |
The present application relates to a novel ABC transporter ATP-binding protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/164118A1 |
The present application relates to a prephenate dehydratase variant.
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WO/2022/163936A1 |
The present application relates to a novel excinuclease ABC subunit A variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163926A1 |
The present application relates to a novel proline dehydrogenase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/158652A1 |
The present application relates to a novel cytosine permease variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/158648A1 |
The present application relates to a novel protein HtrL variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/158645A1 |
The present application relates to a novel deoxyguanosinetriphosphate triphosphohydrolase variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/158535A1 |
A method for producing an objective substance such as phytosphingosine (PHS) and phytoceramide (PHC) using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance an...
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WO/2022/156042A1 |
Provided are an amino acid dehydrogenase mutant and an application thereof. The amino acid sequence of the amino acid dehydrogenase has a sequence as shown in SEQ ID NO: 1, and sites at which amino acid mutation occurs comprise a K144G s...
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WO/2022/158993A1 |
The present invention relates to a method for the production of d-erythro-sphingosine and analogs thereof, wherein the method comprises a step of condensing a compound of formula (2): Formula (2), or a salt thereof, wherein R1 is hydroge...
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WO/2022/158534A1 |
A method for producing an objective substance, such as phytosphingosine (PHS) and phytoceramide (PHC), comprising a desired alkyl chain using yeast is provided. An objective substance is produced by cultivating yeast having an ability to...
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WO/2022/158650A1 |
The present application relates to a novel ferrochelatase variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/158647A1 |
The present application relates to a novel tautomerase pptA variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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WO/2022/158649A1 |
The present application relates to a novel H(+)/Cl(-) exchange transporter variant, an Escherichia coli strain comprising the variant, and a method for producing L-tryptophan using the strain.
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