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WO/2020/120420A1 |
The present invention relates to an enzyme-catalyzed enantioselective method for preparing primary amines from the corresponding imines by using imine reductase enzymes.
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WO/2020/122505A1 |
The present invention relates to a mutant strain having enhanced L-glutamic acid producing ability, and an L-glutamic acid preparation method using same. A mutant strain according to one specific example of the present invention has redu...
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WO/2020/119280A1 |
The present invention relates to the technical field of bioengineering and food, and relates to a method for enzymatic resolution of a chiral substance, comprising the following steps: (1) preparing an enzyme solution having a lipase con...
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WO/2020/113289A1 |
Provided herein is a formulation that contains non-animal-derived hydroxyproline, and one or more of a further amino acid, a sweetening agent, a colouring agent, a flavouring agent, a vitamin, a mineral, a natural extract and/or a pharma...
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WO/2020/113226A1 |
Methods and processes for producing aerobic digestion products, such as organic acids, from a low-rank coal substrate are provided. Also provided are multistage bioreactor systems for carrying out the described methods and processes. In ...
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WO/2020/107780A1 |
Disclosed is a method for preparing (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid by means of a chemoenzymatic method, comprising: using a racemic 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid as a substrate, stereoselectively ...
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WO/2020/109367A1 |
The present invention essentially relates to a method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted whiB4 gene.
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WO/2020/111437A1 |
The present application relates to a CAMP receptor protein mutant, a microorganism comprising same, and a method for preparing L-amino acid by using same.
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WO/2020/112497A1 |
The present disclosure describes the engineering of microbial cells for fermentative production of 1,5-diaminopentane and provides novel engineered microbial cells and cultures, as well as related 1,5-diaminopentane production methods.
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WO/2020/111436A1 |
The present application pertains to a cAMP receptor protein mutant, a microorganism containing same, and an L-amino acid production method using same.
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WO/2020/111438A1 |
The present application pertains to a cAMP receptor protein mutant, a microorganism containing same, and an L-amino acid production method using same.
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WO/2020/099225A1 |
The invention relates to a culture medium, preferably a cell culture medium, comprising at least one keto acid selected from keto leucine, keto valine, keto isoleucine and keto phenylalanine and/or a salt of these keto acids. The inventi...
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WO/2020/090016A1 |
A method for producing an α-keto acid, said method comprising a step of culturing a microorganism, which contains a gene encoding an enzyme catalyzing an aldol reaction between pyruvic acid and a carbonyl compound, in the presence of a ...
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WO/2020/085556A1 |
The present invention relates to a recombinant Corynebacterium glutamicum strain wherein the lysE locus of Corynebacterium glutamicum PKC is transformed with plasmid pK19-mobsacB-lysEF/B, and to a method for producing cadaverine comprisi...
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WO/2020/079152A1 |
Process for producing aqueous polyacrylamide concentrates by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel, comminuting said aqueous polyacrylamide gel and mixing it with ...
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WO/2020/079124A1 |
Process for producing aqueous polyacrylamide compositions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel, comminuting said aqueous polyacrylamide gel and mixing it with ...
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WO/2020/079119A1 |
Method of providing aqueous polyacrylamide concentrates, wherein the process comprises preparing the concentrates at a location A by radically polymerizing an aqueous monomer solution comprising at least water and 1% to 14.9 % by weight ...
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WO/2020/079120A1 |
The present invention relates to a process for preparing ammonium (meth-) acrylate, aqueous ammonium (meth-) acrylate solutions obtainable by such process, and (meth-) acrylic acid homopolymers or copolymers obtainable by polymerizing su...
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WO/2020/070699A1 |
The present invention relates to preparation of key drug intermediate, L-2-amino butyric acid (L-2-ABA) by a method of cell free system and biotransformation using genetically engineered strains from easily available economic substrates ...
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WO/2020/071538A1 |
The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, such as, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a ba...
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WO/2020/067618A1 |
The present application relates to an L-amino acid-producing microorganism exhibiting reinforced α-glucosidase activity, and an L-amino acid production method using same. The L-amino acid-producing Corynebacterium sp. microorganism, acc...
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WO/2020/062961A1 |
An L-aspartic acid α-decarboxylase mutant and an application thereof; the mutant is obtained by mutating lysine at position 221 of L-aspartic acid α-decarboxylase into arginine and by mutating glycine at position 369 into alanine; the ...
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WO/2020/064776A1 |
The invention relates to the use of a composition comprising a rod-shaped, aerobic, Gram-positive microorganism for the degradation of liquid polyether-based polyurethane, and to the composition derived from the degradation of said polye...
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WO/2020/067487A1 |
The present invention provides a method for producing L-methionine by fermentation using a bacterium which has been modified to overexpress a 1st gene and a 2nd gene, such as genes having the nucleotide sequences shown in SEQ ID NOs: 1 a...
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WO/2020/057476A1 |
Provided is an application of trehalase in fermentative production. The trehalase has amino acid sequences shown in SEQ ID NO.6, SEQ ID NO.7, and SEQ ID NO.8. Provided are methods for producing and applying trehalase, particularly being ...
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WO/2020/060970A1 |
The present disclosure generally relates to methods for the recovery of amines from aqueous mixtures. In particular, the disclosure relates to methods for separating amines from amine-containing aqueous mixtures by adjusting the pH of th...
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WO/2020/059480A1 |
Provided are: a method for producing immobilized microorganisms having excellent filtration properties; and a production method for an amino acid using the immobilized microorganisms. This production method for immobilized microorganisms...
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WO/2020/057308A1 |
Disclosed is an NADH-dependent amino acid dehydrogenase and an application thereof in increasing lysine yield. The amino acid dehydrogenases are aspartate dehydrogenase derived from Pseudomonas aeruginos, aspartate semialdehyde dehydroge...
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WO/2020/054598A1 |
Provided is a method for producing a 3-hydroxy-4-aminobenzoic acid compound using a microorganism. A method for producing a 3-hydroxy-4-aminobenzoic acid compound, comprising the step of bringing a 4-aminobenzoic acid compound into conta...
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WO/2020/056410A1 |
Methods for modulating immunosuppression are disclosed. This invention relates the fields of T cell regulation and therapeutic immunosuppression. More specifically, the invention provides compositions and methods for selective immunosupp...
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WO/2020/054934A1 |
The present invention relates to a novel yeast mutant strain for producing a ceramide precursor and a generation method therefor and, more specifically, to a yeast mutant strain for high production of sphingosine or dihydrosphingosine-ce...
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WO/2020/051188A1 |
Compositions and methods for the production of L-glufosinate are provided. The method involves converting racemic glufosinate to the L-glufosinate enantiomer or converting PRO to L-glufosinate in an efficient manner. In particular, the m...
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WO/2020/051420A1 |
This disclosure provides engineered strains of Corynebacteria for the cost-effective production of lysine, tools and methods used to produce the engineered strains, and methods of using the engineered strains to produce lysine.
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WO/2020/043077A1 |
Provided is an enzymatic method for preparing L-threo/erythro-p-methylsulfonylphenyl serine, in particular, a method for preparing L-threo/erythro-p-methylsulfonylphenyl serine by catalyzing glycine and p-methylsulfonylphenyl serine usin...
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WO/2020/036963A1 |
The present invention relates to amorphous and crystalline forms of valbenazine salt and the methods for their preparation.
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WO/2020/034209A1 |
Provided is an amino acid dehydrogenase mutant. The amino acid sequence of the mutant is obtained by mutating the amino acid sequence shown in SEQ ID NO: 1. The mutation comprises at least one of the following mutation sites: 64th, 94th,...
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WO/2020/037338A1 |
A strain of Rhodococcus rhodochrous in which a gene coding at least part of a nitrile hydratase enzyme or any gene coding a protein involved in the transcription, translation or formation of at least part of the nitrile hydratase enzyme ...
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WO/2020/031201A1 |
The present invention relates to highly pure 6-aminohexanoic acid of formula-1 which is free of organic volatile impurities, caprolactam impurity and improved process for its preparation thereof. The present invention also relates to an ...
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WO/2020/025656A1 |
The invention relates to anutritional supplement comprising a combination of one or more β-aspartyl-containing dipeptides,oroligomers thereof, or salts thereof, wherein each of the β-dipeptides comprises β-L-aspartyl as a first amino ...
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WO/2020/025646A1 |
An isolated w-transaminase enzyme comprising an amino acid sequence of SEQUENCE ID NO: 1, or encoded by a nucleic acid sequence of SEQUENCE ID NO: 2, is provided which is derived from marine sponge Pseudovibrio sp.. Also provided are fun...
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WO/2020/027251A1 |
A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective ...
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WO/2020/020844A1 |
The invention pertains to a process for manufacturing aromatic nitriles, wherein a starting material selected from the group of aromatic primary alcohols and aromatic aldehydes is contacted under reaction conditions in a reaction vessel ...
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WO/2020/013346A1 |
A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3'-phosphoadenosine-5'-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobacteri...
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WO/2020/011725A1 |
A method for purifying ethanolamine from a fermentation composition and products thereof.
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WO/2020/009168A1 |
The activity of the wild-type hydroxynitrile lyase (HNL) obtained to date is insufficient for industrial use, and HNL having better activity has been demanded. The present inventors introduced various amino acid mutations predicted on th...
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WO/2020/005834A1 |
Methods and materials related to producing aspartic acid, β-alanine and salts of each thereof are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, methods and materials for producing aspartic acid by direct fer...
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WO/2020/006058A2 |
Described herein are engineered cells including ones having synthetic methylotrophy which include an NADH-dependent enzyme capable of converting G3P to 3PG (e.g., B. methanolicus gapN) and/or fructose-1,6-bisphosphatase, along with hexul...
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WO/2019/243293A1 |
The present invention relates to novel urethanases for the enzymatic degradation of polyurethanes and to an enzymatic process for the complete degradation of polyurethanes in defined monomers.
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WO/2019/243087A1 |
The present invention relates to a process for the preparation of Droxidopa by means of an improved enzymatic reduction of a compound of formula (II): (II), wherein R1, R2 is independent hydrogen, acetyl, R3 is hydrogen, a C1-C4 linear o...
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WO/2019/240579A1 |
The invention provides a production process for the production of an aromatic epoxide derived compound, the production process comprising: (i) an epoxidation stage comprising: reacting an aromatic compound and a peroxide in the presence ...
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