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WO/2020/237552A1 |
Provided are a transaminase mutant and a method for producing chiral amines using the transaminase mutant. The amino acid sequence of the transaminase mutant is an amino acid sequence obtained after mutation occurs to the amino acid sequ...
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WO/2020/232519A1 |
The present invention describes the composition of an animal feed additive containing a nutrient-rich fermented broth obtained by means of a fermentation process using a genetically modified microorganism. The non-pathogenic bacterium Co...
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WO/2020/233451A1 |
Disclosed in the present invention is an L-glutamate dehydrogenase mutant, the sequence of the L-glutamate dehydrogenase mutant being a sequence in which amino acid residue A at position 175 in SEQ ID NO. 1 is mutated to be G, and amino ...
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WO/2020/230044A1 |
The present invention relates to a process for preparing an extract with antimicrobial activity from by-products or waste products of the fruit and vegetable industry. The process comprises a step of mixing the by-products or waste produ...
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WO/2020/231426A1 |
Modified host cell and cyanobacterial cells that are capable of producing various mycosporine-like amino acids (MAAs), useful as natural UV absorbing compound, are described.
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WO/2020/232063A1 |
Disclosed herein are synergistic compositions and methods using arginine -producing bacteria and/or ammonia-consuming bacteria in combination with a checkpoint inhibitor for use in treating cancer.
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WO/2020/226341A1 |
The present application relates to a microorganism producing L-amino acid or a precursor thereof and a method for producing L-amino acid or a precursor thereof by using the microorganism.
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WO/2020/218736A1 |
The present application relates to a microorganism with enhanced L-histidine production capacity and a method for producing histidine by using same.
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WO/2020/219859A1 |
Disclosed are trans-enoyl CoA reductase (TER) enzymes and nucleic acids encoding them. In some cases, the TER enzymes are non- natural, engineered trans-enoyl CoA reductase. TER enzymes were shown to catalyse the conversion of 5-carboxy-...
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WO/2020/219866A1 |
Disclosed are transaminase (TA) enzymes and nucleic acids encoding them. In some cases, the transaminase enzymes are non-natural, engineered transaminases. Also disclosed are biosynthetic methods and engineered microorganisms that enhanc...
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WO/2020/218624A1 |
The present invention addresses the problem of providing a method for more easily and highly efficiently industrially producing high-purity L-cyclic amino acids from cyclic amino acids that have a double bond at the 1 position. According...
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WO/2020/218737A1 |
The present application relates to a microorganism with enhanced L-threonine production capacity, and a production method using same.
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WO/2020/219863A1 |
Disclosed are biosynthetic methods and engineered microorganism that enhance or improve the biosynthesis of hexamethylenediamine, caproic acid or caprolactam. The engineered microorganisms include selected aldehyde dehydrogenase activity.
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WO/2020/213132A1 |
A method for producing a plasmalogen-containing functional material, said method comprising an enzymatic treatment step for treating an animal tissue containing plasmalogen with a protease, and an extraction step for extracting the prote...
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WO/2020/214940A1 |
Described herein are enzymes, such as for example, methanol dehydrogenase (MDH), 3-hexulose-6-phosphate isomerase (PHI), 3-hexulose-6-phosphate synthase (HPS), ribose-5-phosphate isomerase (RPI), ribulose 5-phosphate 3-epimerase (RPE), t...
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WO/2020/208842A1 |
The present disclosure pertains to a genetically modified microorganism that satisfies some of specific requirements. The specific requirements include: (I) compared to a wild type microorganism, having reduced or inactivated succinate d...
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WO/2020/204179A1 |
A method is described for producing an L-amino acid including the steps of cultivating in a culture medium an L-amino acid-producing bacterium belonging to the family Enterobacteriaceae to produce and accumulate the L-amino acid in the c...
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WO/2020/204427A1 |
The present application relates to a protein variant having tryptophan export activity, a microorganism producing L-tryptophan and expressing the protein variant, and a method for producing L-tryptophan using the microorganism.
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WO/2020/198258A1 |
The present disclosure describes the engineering of microbial cells for fermentative production of L-homocysteine and provides novel engineered microbial cells and cultures, as well as related L-homocysteine production methods.
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WO/2020/196619A1 |
The present invention can produce an L-amino acid oxidase at a low cost and in a large quantity through a high expression of a recombinant protein, and the like, and provides a novel L-amino acid oxidase (ArtLAAO) having a wide substrate...
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WO/2020/187271A1 |
Provided is a dual-plasmid system comprising a first plasmid for an expression cassette for expressing a target protein containing a predetermined modified amino acid, a second plasmid for an expression cassette for expressing aminoacyl-...
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WO/2020/187256A1 |
Provided is a method for preparing β-alanine, the method comprising: preparing a β-alanine product from a reactant containing fumaric acid and aqueous ammonia in the presence of a catalyst, wherein the catalyst contains a catalyst comp...
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WO/2020/181779A1 |
A method for preparing a lipoamino acid compound on the basis of a deep eutectic solvent, which relates to the field of organic synthesis. A fatty acid and an amino acid are used as substrates and a deep eutectic solvent is used as a med...
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WO/2020/183033A1 |
The invention provides a fertiliser composition that includes an enhancer of nitrogen that can be assimilated by plants, the enhancer of assimilable nitrogen being tyramine, a combination of the fertiliser composition together with other...
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WO/2020/174101A1 |
Biological solid state fermentation process The invention provides a biological solid state fermentation process wherein an animal residual raw material having a proteic nitrogen content of high value for different industrial processes, ...
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WO/2020/171227A1 |
The present invention provides a method for producing L-amino acids by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress ydiJ gene.
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WO/2020/163935A1 |
The present invention provides biochemical pathways, glyoxylate producing recombinant microorganisms, and methods for the production and yield improvement of glycolic acid and/or glycine via a reverse glyoxylate shunt. The reverse glyoxy...
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WO/2020/155690A1 |
Provided is a system for efficiently catalyzing an aliphatic dinitrile hydration reaction using a new nitrile hydratase. Provided is the brand-new use of nitrile hydratase from Rhodococcus erythropolis CCM2595 in the catalysis of aliphat...
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WO/2020/152104A2 |
The invention is directed to methods for the production of 4-cyano benzoic acid or salts thereof from terephthalonitrile using nitrilase as catalyst and compositions comprising 4-cyano benzoic acid.
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WO/2020/150125A1 |
The present invention provides engineered transaminase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered transaminase polypeptides. Methods for producing transaminase enzymes are also provided. In ...
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WO/2020/147031A1 |
Disclosed are a nitrile hydratase mutant, a genetically engineered bacterium containing the mutant, and the use thereof, falling within the technical field of enzyme engineering. According to the present invention, glycine at position 47...
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WO/2020/146587A1 |
Compositions for improving the bioavailability of methionine. In general, the compositions comprise a source of methionine and essential oil(s). More specifically, the compositions comprise a source of methionine and a plurality of coate...
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WO/2020/144371A1 |
The present invention relates to a recombinant microbial host cell comprising an operative biosynthetic metabolic pathway capable of producing one or more compounds selected from the group consisting of L-dopa, dopamine, (S)-Norcoclaurin...
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WO/2020/140388A1 |
A glutamic acid fermentation process, comprising the following steps: introducing Corynebacterium glutamicum into a fermentation tank filled with a clean fermentation medium for fermentation culture, performing ultrasonic treatment, and ...
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WO/2020/136236A1 |
The invention relates to a method and a device device for converting at least one reactant(5) into a reaction product and separating the at least one reactant from the reaction product, wherein the device comprises a vessel (10) with a v...
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WO/2020/135000A1 |
Disclosed is a preparation method for 3-phenyl-L-serine or derivatives thereof, comprising the following steps: a. obtaining 3-phenyl-L-serine or derivatives thereof on the basis of the reaction formula represented by Formula I, wherein ...
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WO/2020/138178A1 |
The present invention provides a method for producing a basic L-amino acid such as, for example, L-ornithine L-citrulline, L-arginine, L-histidine, and L-lysine by fermentation using a bacterium belonging to the family Enterobacteriaceae...
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WO/2020/133989A1 |
Disclosed are an amino acid dehydrogenase mutant and the use thereof in the synthesis of L-glufosinate. The amino acid dehydrogenase mutant is obtained by performing a single mutation or multiple mutations on amino acids at positions 95,...
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WO/2020/134689A1 |
A hericium erinaceus HT-3 with a preservation number of CCTCC No: M 2018567 and a screening method thereof, the screening method comprising steps such as obtaining a purified strain containing a hericium erinaceus tissue block; performin...
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WO/2020/134687A1 |
A method for preparing ergothioneine by biosynthesis. The method comprises the following steps: 1) strain inoculating, on slant, mycelia of Hericium erinaceus into a liquid seed medium for cultivation, so as to obtain a seed liquid; 2) i...
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WO/2020/138919A1 |
The present application relates to: an ornithine decarboxylase or a protein variant thereof; a polynucleotide encoding same; a microorganism containing same; and a method for producing putrescine by using same. The present invention achi...
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WO/2020/138815A1 |
The present invention pertains to: an L-amino acid-producing E. coli variant strain or Corynebacterium glutamicum variant strain having an enhanced ability to produce L-amino acids; and a method for producing L-amino acids using same. Th...
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WO/2020/138543A1 |
The present invention relates to a generation method for an ornithine decarboxylase mutant strain, characteristics of the mutant strain, a gene encoding the ornithine decarboxylase mutant strain, and a method for producing putrescine usi...
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WO/2020/133990A1 |
The present invention discloses a glufosinate dehydrogenase mutant and an application thereof in synthesizing L-glufosinate, the method using 2-carbonyl-4-(hydroxy-methyl-phosphoryl) butyric acid or a salt thereof as a substrate; in the ...
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WO/2020/133126A1 |
Disclosed is a method for preparing phosphatidylserine by ultrasonic assisted enzymolysis, comprising the following steps: adding 100-130 parts of a phospholipid to a mixture containing 150-200 parts of L-serine, 10-20 parts of anhydrous...
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WO/2020/130236A1 |
The present application pertains to a modified homoserine dehydrogenase, and a method for producing homoserine or a homoserine-derived L-amino acid using same.
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WO/2020/128434A1 |
Disclosed herein is a method of reducing an aromatic nitro compound. In some embodiments the method comprises the step of (i) contacting an aromatic nitro compound with a catalyst, wherein, the catalyst comprises: (a) disproportionation ...
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WO/2020/126484A1 |
The present invention relates to a process for biocatalytic amidation of non-protected amino acids comprising the step of contacting a non-protected amino acid with an ammonia source in the presence of an organic solvent and an enzyme.
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WO/2020/131574A1 |
A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.
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WO/2020/130384A1 |
The present invention relates to a method of producing beta or gamma amino acids using a glutamic acid regeneration reaction. The present invention can induce the production of high concentrations of beta and gamma amino acids by using g...
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