| Document |
Document Title |
|
WO/2021/090925A1 |
Provided are a polypeptide having excellent 4-aminobenzoic acid hydroxylation activity and a method for using the polypeptide. This polypeptide having 4-aminobenzoic acid hydroxylation activity comprises an amino acid sequence represen...
|
|
WO/2021/089584A1 |
The present invention relates to a method of storing a biocatalyst, which biocatalyst is capable of converting acrylonitrile to acrylamide, comprising the steps: (a) providing an aqueous suspension comprising the biocatalyst, which is ca...
|
|
WO/2021/088604A1 |
Provided is a method for continuously preparing [14/15N]-L-citrulline by means of an immobilized enzyme. The method comprises: suspending, in a packed bed reactor, a fusion protein cipA-arc formed by fixing an arginine deiminase arc to a...
|
|
WO/2021/088603A1 |
Provided is an arginine deiminase-containing genetic engineering corynebacterium glutamicum having a preservation number of CGMCC No.19404, which expresses a cipA-arc fusion protein. The engineering bacteria and the cipA-arc fusion prote...
|
|
WO/2021/081713A1 |
Provided are a transaminase mutant and application thereof. The transaminase mutant has an amino acid sequence obtained by mutation of the amino acid sequence shown in SEQ ID NO:1, the mutation at least comprises one of the following mut...
|
|
WO/2021/085999A1 |
The present application relates to a metZ gene-introduced, L-methionine producing microorganism and a method for producing L-methionine using same.
|
|
WO/2021/085795A1 |
Disclosed is a mutant strain having improved aromatic amino acid production capabilities as a result of the inactivation or weakening of the activity of asparaginase which is expressed by ansB gene.
|
|
WO/2021/085794A1 |
Disclosed is a mutant strain having an improved aromatic amino acid production capability due to the weakening or inactivation of the activity of an FMN/FAD transport protein which is expressed by the yeeO gene.
|
|
WO/2021/086036A1 |
The present invention relates to a method for fixing and stabilizing nitrogen oxide metabolites through fermentation of a nitrogen-containing natural product. The method of the present invention has optimized a fermentation condition so ...
|
|
WO/2021/085796A1 |
Provided is a mutant strain having improved aromatic amino acid production capabilities as a result of the inactivation or weakening of the activity of glutaminase which is expressed by glutaminase B (glsB) gene.
|
|
WO/2021/077425A1 |
Disclosed in the present invention are a transaminase mutant and a use thereof. The amino acid sequence of the transaminase mutant is an amino acid sequence obtained by mutating an amino acid sequence shown as SEQ ID NO: 1, and the mutat...
|
|
WO/2021/080277A1 |
The present invention relates to a novel enzyme for producing D-threonine. When reactions are carried out by using the enzyme of the present invention, the ratio of diastereomer D-allo-threonine, which can be produced together with D-thr...
|
|
WO/2021/077455A1 |
A genetically engineered strain having high-yield of L-valine. Starting from Escherichia coli W3110, the acetolactate synthase gene alsS of Bacillus subtilis is integrated and strongly expressed on a genome thereof; the Escherichia coli ...
|
|
WO/2021/081222A1 |
Disclosed herein are recombinant host cells and methods capable of producing a tyramine containing hydroxycinnamic acid amide compounds, derivatives and extracts. Some embodiments provided include, for example, consumable products contai...
|
|
WO/2021/070942A1 |
The present invention provides an enzyme or the like useful for establishment of an excellent N-acyl-amino group-containing compound production system. More specifically, the present invention provides a modified enzyme or the like inclu...
|
|
WO/2021/060701A1 |
The present application relates to a variant polypeptide with reduced meso-diaminopimelate dehydrogenase activity and a method for producing L-threonine using same.
|
|
WO/2021/060438A1 |
The present invention provides a method for producing L-amino acids by fermentation using a bacterium belonging to the order Enterobacterales which has been modified to attenuate expression of a gene encoding a protein having indolepyruv...
|
|
WO/2021/060696A1 |
The present application relates to a modified polypeptide with attenuated dihydrodipicolinate reductase activity, and a method for producing L-threonine by using same.
|
|
WO/2021/058691A1 |
The invention is directed to methods to produce β-alanine or salts thereof from acrylic acid using a recombinant aspartase-like protein as catalyst.
|
|
WO/2021/052989A1 |
The present disclosure relates to methods for production of 4-hydroxytryptamine and derivatives thereof in a yeast cell. Herein are also disclosed methods for production of halogenated tryptophans and derivatives thereof in a cell. Herei...
|
|
WO/2021/048353A1 |
The present invention provides a recombinant bacterium of the genus Corynebacterium comprising a L-threonine exporter gene rhtC from E. coli and wherein in said bacterium the native L-threonine transporter gene thrE is deleted and a meth...
|
|
WO/2021/049852A1 |
The present invention relates to a composition that is effective in improving skin wrinkles and inflammation, comprising, as an active ingredient, a cell extract of a Lactobacillus paracasei subsp. tolerans SW1 strain newly isolated from...
|
|
WO/2021/049866A1 |
The present application relates to an L-threonine export protein variant, a microorganism including same, and a method for production of L-threonine using same.
|
|
WO/2021/042460A1 |
A transport protein coding gene, and a method for using a strain containing said gene to increase L-tryptophan production. Specifically, strain L-tryptophan production efficiency can be improved by means of heterologous expression of the...
|
|
WO/2021/043451A1 |
The invention provides polynucleotides and nucleic acid molecules encoding piperine synthases and proteins and enzyme functional for converting piperoyl-CoA and piperidine to piperine. The invention also provides a method of producing an...
|
|
WO/2021/045472A1 |
The present application relates to a novel promoter and a method for producing a desired substance using same.
|
|
WO/2021/037166A1 |
Provided are an Escherichia coli strain K12-based recombinant strain or a derivative strain thereof after site-directed mutagenesis, a construction method therefor and use thereof. Said recombinant strain is subjected to site-directed mu...
|
|
WO/2021/038095A1 |
The present invention relates to methods for the preparation of α-hydroxyacyl compounds, and peptides for the catalyzed formation of α-hydroxyacyl compounds as well as their use in the preparation of α-hydroxyacyl compounds.
|
|
WO/2021/037165A1 |
Provided is a nucleotide sequence. The sequence is a sequence formed by mutation of a base at the 1049th site of a wild-type deoB gene coding sequence shown in SEQ ID NO: 1 or a promoter nucleotide sequence by mutation of a base at the -...
|
|
WO/2021/041932A2 |
Provided herein, inter alia, are genetically engineered microbes and methods of use thereof for producing L-4-chlorokynrenine from L-Tryptophan. The genetically engineered microbes include, inter alia, one or more exogenous nucleic acids...
|
|
WO/2021/035793A1 |
Provided is an MviN protein mutant, said mutant improving corynebacterium glutamic acid and lysine production capability by means of introducing an amino acid mutation at a set position in an MviN protein amino acid sequence.
|
|
WO/2021/037190A1 |
Provided are a 2-isopropylmalate synthase, L-leucine-producing genetically engineered bacteria, and applications thereof, related to the field of metabolic engineering. The genetically engineered bacteria are acquired by overexpressing i...
|
|
WO/2021/036901A1 |
An application of a branched-chain α-ketoacid dehydrogenase complex in preparation of malonyl coenzyme A. A method for preparing malonyl coenzyme A by using the branched-chain α-ketoacid dehydrogenase complex. The method comprises: int...
|
|
WO/2021/032513A1 |
The present invention relates to a process, by means of which polyurethanes, which have been formed from polyether polyols and aromatic isocyanates, can be decomposed to polyether polyols and aromatic amines.
|
|
WO/2021/030835A1 |
The present disclosure describes the engineering of microbial cells for fermentative production of 3-anino-4-hydroxybenzoic acid and provides novel engineered microbial cells and cultures, as well as related 3-amino-4-hydroxybenzoic acid...
|
|
WO/2021/017317A1 |
A method for inhibiting the photodegradation of ergothioneine, and an application therefor, comprising the following steps: adding hyaluronate to a solution containing ergothioneine; the content of ergothioneine is 0.0005-0.01 wt%, and t...
|
|
WO/2021/015242A1 |
[Problem] To provide a genetically modified microorganism and a method for producing a diamine compound. [Solution] This genetically modified microorganism expresses an enzyme involved in synthesis of a diamine compound, wherein the diam...
|
|
WO/2021/010268A1 |
Provided is a method for producing an N-substituted amide compound/amide compound copolymer using a biocatalyst, the method comprising: (A) a step for reacting an amide compound with an amine in the presence of an enzyme that catalyzes a...
|
|
WO/2021/007127A1 |
Disclosed herein are methods for the selective substitution of a hydrogen bonded to a carbon atom (e.g., a hydrogen of an aliphatic methylene group) of a compound, which comprise contacting the compound with a substituent in the presence...
|
|
WO/2021/002195A1 |
The present invention addresses the problem of providing a practical means for producing cysteine from glutathione, said means being suited for use in the field of foodstuffs. The present invention produces cysteine from glutathione usin...
|
|
WO/2020/262860A1 |
The present invention relates to a method for increasing the content of tryptophan in bean sprouts by using a plant elicitor, and extracting the tryptophan therefrom and, more particularly, to a method for building up tryptophan as a use...
|
|
WO/2020/263722A1 |
The present strains and methods relate to yeast cells that over-overproduce selected endogenous proteins having a high amino acid content of a selected amino acid. The yeast can be used in a conventional bioethanol production facility to...
|
|
WO/2020/263732A1 |
Described are compositions and methods relating to yeast having a genetic mutation that results in decreased amounts of Cdc42 effector proteins, resulting in increased alcohol and lysine production. Such yeast is well-suited for use comm...
|
|
WO/2020/263041A1 |
The present application relates to a method for producing a sulfur-containing amino acid or a sulfur-containing amino acid derivative.
|
|
WO/2020/263043A1 |
The present application relates to a method for producing a sulfur-bearing amino acid or a sulfur-bearing amino acid derivative.
|
|
WO/2020/254699A1 |
The present invention relates to a method for municipal solid waste (MSW) reclamation in a continuous or discontinuous process, first for converting said waste into organic biomass and subsequently extracting and recovering as many of th...
|
|
WO/2020/256415A1 |
The present invention relates to microorganisms for producing L-tyrosine, including a gene for encoding a trp operon regulatory region and a prephenate dehydratase operably linked thereto, and a method for producing L-tyrosine by using t...
|
|
WO/2020/249616A1 |
A method of upregulating the synthesis of pyruvate and/or a metabolite of pyruvate in a photosynthetic microorganism, a method for the photosynthetic production of a one, two, three or four carbon compounds, and a method for the producti...
|
|
WO/2020/244380A1 |
Provided is a means of knocking out the glnR gene by means of homologous recombination, and a method and application thereof for obtaining a Lactobacillus brevis glnR knockout strain to improve the ability of Lactobacillus brevis γ-amin...
|
|
WO/2020/237701A1 |
Provided are a high-yield L-histidine genetically engineered bacterium strain, and a construction method therefor and an application thereof, integrating a corynebacterium glutamicum ATP phosphoribosyl transferase HisG mutant encoding ge...
|
