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WO/2021/235775A1 |
The present application relates to: a novel mutant polypeptide having isopropylmalate synthase activity; and a method for producing L-leucine by using same. L-leucine can be produced at high yield by using the mutant polypeptide accordin...
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WO/2021/235855A1 |
The present invention relates to an L-branched chain amino acid producing microorganism having enhanced activity of an acetic acid metabolism regulator A and a method for producing an L-branched chain amino acid at high efficiency by cul...
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WO/2021/227500A1 |
A recombinant microorganism for producing L-valine, a construction method therefor, and an application thereof. By introducing an acetohydroxy acid reductoisomerase gene and/or an amino acid dehydrogenase gene into a microorganism, and i...
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WO/2021/217773A1 |
Provided in the present invention are a transaminase mutant and use thereof. Compared with an amino acid sequence shown in SEQ ID NO: 1, an amino acid sequence of the transaminase mutant comprises at least one of the following mutation s...
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WO/2021/214278A2 |
The present invention relates to regioselective chemical and electrochemical processes for the preparation of an oxidized heterocyclic alpha-amino amide compounds. By applying specific catalysts or catalyst systems during chemical oxidat...
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WO/2021/214345A1 |
The present invention provides a method for producing a biomass comprising at least 65% protein from hydrogen-oxidising microorganisms using one or more input streams comprising one or more gaseous substrates and a nutrient composition w...
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WO/2021/214283A1 |
The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as furt...
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WO/2021/204095A1 |
Provided is a production equipment of phenethylamine, comprising a first reaction device (1); a second reaction device (2), wherein the second reaction device (2) is connected to the first reaction device (1); and a circulation device (4...
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WO/2021/204850A1 |
The present invention provides a process for producing an aqueous blend of ammonium (meth) acrylate and (meth) acrylamide, which blend is suitable for producing copolymers of ammonium (meth) acrylate and (meth) acrylamide, said process c...
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WO/2021/197632A1 |
The invention relates to an enzyme for the reduction of cystine to cysteine, characterized in that the enzyme is a fusion protein comprising the protein activities of thioredoxin (protein i) having the KEGG database number EC 1.8.4.8 or ...
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WO/2021/198273A1 |
The invention provides a method for the enzymatically catalyzed synthesis of a diol from an amino acid, the method comprising the steps of a. Enzymatically hydroxylating the amino acid, b. Enzymatically deaminating the amino acid, the de...
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WO/2021/201489A1 |
The present invention relates to a strain which has improved glutamine productivity due to being transformed by a vector including a nucleotide sequence that encodes a glutamine synthetase comprising an amino acid sequence of SEQ ID NO: 1.
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WO/2021/185039A1 |
Provided are a Rhodotorula toruloides engineering bacteria and a construction method therefor. The Rhodotorula toruloides engineering bacteria can express exogenous egt1 enzymes, so as to improve the capacity for producing ergothioneine....
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WO/2021/184557A1 |
Disclosed in the present invention is a method for preparing L-glufosinate-ammonium by means of asymmetric oxidization-reduction with a biological multienzyme coupling method. The method comprises: taking D,L-glufosinate-ammonium as a ra...
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WO/2021/185191A1 |
Improved processes for producing bio-based nylon precursors having reduced organic and inorganic impurities are described herein. The processes generally comprise fermenting a microorganism engineered to produce lysine in a modified cult...
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WO/2021/187781A1 |
The present application relates to a method for producing L-tryptophan through the enhancement of prephenate dehydratase (PheA) activity.
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WO/2021/182742A1 |
The present application relates to a granular feed additive production method. By using the granular feed additive production method, according to one embodiment, a granular feed additive may be produced, which contains a high content of...
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WO/2021/177731A1 |
The present application relates to an activity-enhanced glutamine synthetase mutant-type polypeptide, and a method of producing L-glutamine by using same. The use of the novel mutant-type polypeptide, compared to that of a strain having ...
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WO/2021/168988A1 |
The present invention provides a synthesis method for a fluorine-containing chiral amine compound. The synthesis method comprises: reacting an amino donor with a fluorine-containing dihydroxy ketal compound under the catalysis of transam...
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WO/2021/172546A1 |
Provided is a digestive enzyme agent which can promote the liberation of a protein into BCAAs in an in vivo environment. A digestive enzyme agent comprising a protease derived from a koji mold can promote the liberation into BCAAs in an ...
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WO/2021/169490A1 |
Provided is a nitrilase mutant and application thereof in the preparation of 1-cyanocyclohexaneacetic acid, the mutant being obtained by mutating one or more of the 180th and 205th amino acids in the amino acid sequence shown in SEQ ID N...
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WO/2021/168987A1 |
Provided is a method for synthesizing a chiral diamine compound. The synthesizing method comprises: converting a substrate represented by formula I into a formula I chiral diamine compound by using transaminases, wherein n=1-10, an R gro...
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WO/2021/163780A1 |
The disclosure provides processes for the production of ethanol and one or more co-products from a fermentable carbon source. The ethanol and one or more co-products are produced in an ethanol-producing yeast modified to further produce ...
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WO/2021/159828A1 |
Provided are an enzyme having an acyl group transfer function as well as a mutant and application thereof, an amino acid sequence of the acyltransferase being that of SEQ ID NO: 1, and same being able to perform acylation on Macrolactins...
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WO/2021/162459A1 |
Provided are a microorganism comprising variant LysE, and an L-amino acid producing method using same. The variant LysE may improve L-amino acid excretion and/or production capacity compared to a wild type.
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WO/2021/162189A1 |
The present invention relates to a Corynebacterium glutamicum mutant strain having an improved L-glutamic acid production ability, a method for producing same, and a method for producing L-glutamic acid using same, wherein the Corynebact...
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WO/2021/153866A1 |
The present application pertains to a novel mutant polypeptide with attenuated activity of citrate synthase, a leucine-producing microorganism comprising the mutant polypeptide, and an L-amino acid production method using the microorganism.
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WO/2021/151025A1 |
A protein hydrolysate composition derived from a microorganism, such as a chemoautotrophic microorganism, and methods of preparing and using the same are provided. The protein hydrolysate composition may be produced sustainably through f...
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WO/2021/147558A1 |
Provided are a nitrilase mutant and the use thereof in the preparation of an anti-epileptic drug intermediate. The mutant is obtained by means of mutating one or more of the amino acids at positions 151, 223 and 250 of the amino acid seq...
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WO/2021/143356A1 |
Disclosed is a method for preparing L-2-aminobutyric acid by means of double enzyme series connection, relating to the field of bioengineering. By respectively culturing recombinant Escherichia coli expressing L-glutamate mutase and L-as...
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WO/2021/143468A1 |
Provided are a carrier comprising a temperature switch loop and application thereof in increasing the yield of threonine in microbial cells. According to the carrier, heterologous expression of pyruvate carboxylase is controlled, tempera...
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WO/2021/140980A1 |
Provided are: a transformed cell having the capability of producing a 2,5-pyridine dicarboxylic acid; and a method for producing a 2,5-pyridine dicarboxylic acid by using the transformed cell. In microorganisms having the capability of...
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WO/2021/140693A1 |
Microorganisms according to the present invention are Dirkmeia churashimaensis (NITE BP-03054), Papiliotrema flavescens (NITE BP-03051), Papiliotrema flavescens (NITE BP-03052), or Apiotrichum porosum (NITE BP-03053).
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WO/2021/134439A1 |
Provided is a method for improving the transesterification activity of phospholipase D, the method comprising: adding an alcohol substance to an enzymatic reaction system for the enzyme-catalyzed production of phosphatidylserine, wherein...
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WO/2021/134440A1 |
Provided is a method for resisting viscosity during enzyme-catalyzed production of phosphatidylserine, comprising: adding an ethanol solution with a pH value of 7.5-9.5 into a crude product obtained during enzyme-catalyzed production of ...
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WO/2021/133101A2 |
Provided are a mycosporine-like amino acid-producing microorganism and a method for production of mycosporine-like amino acids by using same. The microorganism can produce mycosporine-like amino acids from xylose.
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WO/2021/133030A1 |
Provided are a microorganism for producing L-amino acid, having increased cytochrome C activity, and an L-amino acid production method using the microorganism.
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WO/2021/131555A1 |
Provided is a method for producing a fermentation product wherein the characteristics of a liquid and a solid are measured while minimizing the effect of bubbles mixed in the liquid on the measurement results of a sensor and, at the same...
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WO/2021/131627A1 |
Provided is a means for preparing a free ceramide (Cer) from a glycosylinositolphosphoceramide (GIPC). More specifically, provided is a composition for lysing a glycosylinositolphosphoceramide (GIPC) or a glucosylceramide for producing a...
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WO/2021/076917A9 |
Provided herein are genetically modified yeast cells that recombinantly expresses a gene encoding a mutant beta-lyase. Also provided are methods of producing fermented products and methods of producing ethanol.
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WO/2021/126961A1 |
Aspects of the disclosure relate to biosynthesis of histidine in host cells. For example, host cells may comprise: a promoter; a ribosome binding site (RBS); and a nucleic acid comprising: hisG; hisD; hisC\ hisB; hisH; hisA; hisF; and/or...
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WO/2021/122400A1 |
The present invention relates to a microorganism transformed to be capable of producing guanidinoacetic acid (GAA) by increased expression of L-arginine:glycine amidotransferase, carbamoyl phosphate synthase and argF, argG and argH of ar...
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WO/2021/125896A1 |
The present application relates to: a mutant of YjeH, which is an inner membrane protein, a microorganism comprising same; and a method for producing a target product by using same.
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WO/2021/118137A1 |
The present invention relates to a method for enzymatically producing beta amino acids by using a novel ester hydrolase, and more specifically, to a method whereby the productivity of a beta-amino acid can be increased by using a novel e...
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WO/2021/109467A1 |
Disclosed are gene engineering bacteria for producing L-arginine and a construction method and an application of the gene engineering bacteria. According to the method, a gene for encoding carbamyl phosphate synthetase and a gene for enc...
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WO/2021/112469A1 |
The present application relates to a novel branched-chain amino acid aminotransferase mutant and a leucine production method using same.
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WO/2021/108667A2 |
Certain embodiments provide a method of reducing biuret in a urea composition, the method comprising contacting the urea composition with an isolated or purified biuret hydrolase enzyme under conditions suitable to reduce the concentrati...
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WO/2021/102737A1 |
The present invention discloses a S-adenosyl-L-methionine δ24-sterol-C-methyltransferase mutant C24MTgm-M11. Strain MG1655 (ΔptsG ΔfumAC ΔfumB, panD, aspA, C24MTgm) is constructed based on the polynucleotide encoding the enzyme mutan...
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WO/2021/102736A1 |
Provided herein are a method for producing ergothionine, comprising N (α) -trimethyl histidine and an oxidative sulfurizing enzyme mutant. With the mutant enzyme's help, the conversion rate is higher than 30%with the mutant enzyme amoun...
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WO/2021/101000A1 |
The present application relates to an acetohydroxyacid synthase variant, polynucleotides coding for same, microorganisms comprising the variant, and a method for producing L-isoleucine using the microorganisms.
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