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WO/2023/147674A1 |
Provided herein are reagent plates, digital microfluidics ("DMF") cartridges and systems, and methods for using the same. The reagent plate may be used for easily preparing, storing, stabilizing, transporting, and/or dispensing reagents ...
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WO/2023/150232A1 |
A system and/or method for determining an immune activation state of a subject can include: deforming leukocytes within a microfluidic channel, acquiring a plurality of images of the leukocytes, determining biophysical parameters of the ...
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WO/2023/147908A1 |
In a device (1) and a method for examining and processing a biological or medical sample, a dispensing unit (3) serves to dispense the sample into a depression of a sample holder (10). The sample holder (10) has an aspect ratio of the he...
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WO/2022/245826A9 |
The present invention includes compositions and methods for using and manufacturing hydrogel template particles with micropores and/or a nanoporous structure.
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WO/2023/150581A1 |
Described herein are systems and methods for sorting particles in fluids. Systems may comprise a microfluidic chamber, at least one array of electrodes arranged on the substrate, and a controller. The microfluidic chamber is configured t...
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WO/2023/150378A1 |
An automated sampling platform includes a gantry-style 2D or 3D actuator equipped with a syringe pump end effector configured to extract samples from a rubber septum placed in-line within a tubing-based system and to deposit the extracte...
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WO/2023/149787A1 |
The present invention relates to a nucleic acid analysis device including an infectious agent separation and concentration function. The present invention provides a nucleic acid analysis device including an infectious agent separation a...
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WO/2023/141944A1 |
A separation apparatus (100), comprising a separation chip (10, 10'), an oscillation system (70), a differential pressure driving system (50), a frequency conversion module (40) and a controller (60). The separation chip (10, 10') compri...
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WO/2023/146022A1 |
A liquid refining apparatus is disclosed. The liquid refining apparatus includes a substrate, a loader which is formed on the substrate and configured to receive a first liquid, a filter which is configured to reduce a concentration of a...
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WO/2023/144553A1 |
A microfluidic network of a polymeric microfluidic strip includes a liquid sample input port, a reagent zone, a detection zone, and a compressible chamber in fluidic communication via the microfluidic network. A polymer layer overlies th...
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WO/2023/144192A1 |
The invention relates to a device which is preferably microfabricated, having a positioning device for sequential positioning of particles, wherein the positioning device has a preferably rigid delimitation structure, wherein the delimit...
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WO/2023/142260A1 |
An on-chip microgroove array digital PCR chip based on electrical impedance detection, comprising a microgroove array, a power supply module, a clock generation module, a digital control logic module, a driving module, an analog-to-digit...
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WO/2023/143004A1 |
A liquid injection apparatus, a detection method, and a medical device. The liquid injection apparatus comprises a mounting bracket (10), a diluent container (20), and a liquid injection assembly (30). The mounting bracket (10) is provid...
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WO/2023/144713A1 |
Apparatus and methods are described for analyzing a bodily sample. A sample carrier (22), which houses the bodily sample, includes at least one fluidic channel (120), at least one analysis chamber (68), and a receptacle (92) that houses ...
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WO/2023/146869A1 |
Devices, systems, and methods related to autonomous directional valves that allow fluids to stop and flow based on progressive changes in pressure are generally described.
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WO/2023/147003A1 |
The present subject matter relates to devices and techniques for reducing the parabolic velocity profile. The disclosed device can include a coflow generator configured to receive a buffer solution and a mixture of at least two component...
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WO/2023/146021A1 |
A fluid separation apparatus is disclosed. The fluid separation apparatus includes a diluter which includes a first filter channel through which a fluid flows, a fluid structure formed to protrude outward from the first filter channel an...
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WO/2023/147002A1 |
Various embodiments described herein include methods and devices for the evaluation of sub-cellular and molecular structures of cells and particles. In one aspect, a microfluidic device includes: (i) a sensor positioned adjacent to a mic...
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WO/2023/147356A1 |
A cell deactivation device includes a cell deactivation container. The cell deactivation container includes a plurality of microfluidic channels, a lid covering the plurality of microfluidic channels, the lid having a thickness of less t...
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WO/2023/146067A1 |
The present invention provides a biofluid sample preprocessing apparatus and a biofluid sample preprocessing method using same, the biofluid sample preprocessing apparatus comprising: a sample inlet; a medium inlet; a central fluid chann...
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WO/2023/146594A1 |
A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A s...
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WO/2023/147000A1 |
A microfluidic device and a method for sensing and sorting of cells or particles in a microfluidic channel are disclosed. The microfluidic device may include a substrate with a microfluidic channel having an inlet, the microfluidic chann...
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WO/2023/146456A1 |
A material mixing cartridge for a dispensing system comprises a dispensing chamber, with a material dispensing outlet and a dispensing actuator for dispensing material through the material dispensing outlet. The mixing cartridge further ...
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WO/2023/146404A1 |
A device for detecting at least one analyte, for example a cell, in a sample fluid, the device comprising a fluid channel having a longitudinal channel axis and structured to allow the sample fluid containing at least one analyte to pass...
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WO/2023/146870A1 |
Systems and methods related to microfluidic devices (e.g., microfluidic devices comprising layers of films) are generally described. In some embodiments, a microfluidic device comprises a substrate configured to facilitate fluid transpor...
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WO/2023/144530A1 |
The described invention is a cell counting device for counting target cells within a fluid, the device comprising: a microfluidic channel configured to receive a flow of a cell-containing fluid through an inlet and conduct the flow of th...
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WO/2023/026286A9 |
Methods and apparatus are disclosed for preparing plasma enriched with Interleukin Receptor 1 antagonist ("IL-IRa") using glass beads or polyacrylamide microbeads and recovering the plasma enriched in IL-IRa with a filter.
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WO/2023/141047A1 |
An assembly for securing a film to an object is provided. The assembly may comprise a lid comprising a surface configured to receive the film, where the surface comprises a plurality of vent openings through which positive pressure or va...
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WO/2023/141284A1 |
A microfluidic valve comprising an adhesive tape, an outlet disposed at one end of a first microfluidic channel, an inlet disposed at one end of a second microfluidic channel, wherein the inlet and the outlet are disposed in a proximity ...
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WO/2023/138655A1 |
It relates to methods, reagents, compositions, and systems for particle distribution and cell analysis. Cells and adjustable droplets each with a particle encapsulated therein can be distributed into microwells of a microwell array. The ...
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WO/2023/138858A1 |
The invention relates to a method for marking objects made of plastic for laboratory use, wherein a dark-colored contrast surface is produced in the plastic of the object using laser beams, and a light-colored writing is produced in the ...
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WO/2023/141244A1 |
A microfluidic device for droplet electroporation includes a channel having an inlet, and outlet, a channel thickness, a channel width, and a first end and a second end defining a channel length, wherein the channel is configured to rece...
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WO/2023/138793A1 |
Device (1) for receiving biological samples for carrying out a PCR analysis method for determination of pathogenic microorganisms, in particular pathogenic viruses, especially viruses that cause respiratory diseases, having - a receiving...
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WO/2023/141476A1 |
Disclosed are assemblies, systems, and methods for transilluminating a sample disposed within a device. An assembly includes a first optically transparent substrate configured to receive a biological sample, a second optically transparen...
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WO/2023/138988A1 |
The invention relates to a method for separating HMW DNA and/or UHMW DNA from a carrier element (8), to which the DNA is removeably attached, using a centrifugation container set (2) with at least one centrifugation container (10a, 10b, ...
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WO/2023/139272A1 |
The present invention relates to a device for creating a cylindrical hydrogel.
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WO/2023/139383A1 |
The present invention concerns a connector including a housing, extending between a distal end and a proximal end; a hollow needle mounted, at least partially, within the housing, a first end of the hollow needle being connected or conne...
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WO/2023/140613A1 |
The present invention provides a fluorometric assay substrate for the simultaneous measurement of glucose and lactate, wherein an identical substrate (Amplex Red) that reacts with glucose and lactate and a catalyst (horseradish peroxidas...
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WO/2023/137645A1 |
The methods, reagents, compositions, and systems for particle distribution and cell analysis. Cells and adjustable droplets each with a particle encapsulated therein can be distributed into microwells of a microwell array. The encapsulat...
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WO/2023/138810A1 |
The invention relates to a microfluidic device (100) for processing a sample, wherein the device (100) comprises an amplification functional module (110) having a microfluidic channel (115) for guiding a fluid, a dry reagent pre-storage ...
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WO/2023/140479A1 |
A target inspection kit is disclosed. Particularly, a target inspection kit comprises: a target extraction unit in which an extraction solution is accommodated and sealed; a grip unit which can be gripped by the hand of a user, and which...
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WO/2023/137583A1 |
A method for determining an effect relationship between various substances and cells, comprising: providing a first droplet, a second droplet, a third droplet, and a microwell array chip, a plurality of microwell combinations being provi...
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WO/2023/135575A1 |
Described herein are systems, methods, and devices for pathogen identification. A system includes a housing configured to receive a sample comprising pathogen(s), a pipettor system disposed inside the housing, centrifuge(s) disposed insi...
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WO/2023/136896A1 |
A system or method for detecting an immune system activation state in a patient can include a sample preparation system configured to isolate white blood cells from a sample of the patient by using spindle configured to attach to the tes...
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WO/2023/135038A1 |
The invention relates to a device for collecting a sample from a septum (100), said device comprising a hollow body (4) that receives a needle (2) securely mounted on a support (20), and comprising an internal reservoir (3) connected to ...
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WO/2023/134167A1 |
An activated clotting time (ACT) test chip (1). The ACT test chip (1) comprises a chip body (101) and a chip housing (102); a front end of the chip body (101) is a chip test end (10101), and the chip body (101) is further provided with a...
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WO/2023/133377A1 |
A multi-well assay plate is provided. The multi-well assay plate includes at least a top plate that defines a plurality of wells and a base plate having a substrate (3100) with well electrode structures (3101) patterned thereon. The well...
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WO/2023/131694A1 |
A patch-clamp system, and associated processes, are provided. The patch-clamp system comprises a multi-well patch-clamp plate and a manifold, and can provide improved liquid control in patch-clamp experiments.
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WO/2023/131714A1 |
The present invention relates to a chip for micro-organism mechanical lysis comprising a lysing chamber, a mechanical system operating with such chip and methods of micro- organism mechanical lysing.
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WO/2023/130839A1 |
A membrane forming support (10), a biochip, a device, preparation methods, and applications thereof. The membrane forming support (10) comprises an insulating substrate (2) and an insulating layer (1); the insulating layer (1) is provide...
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