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WO/2023/164635A9 |
The present disclosure relates to an apparatus, method, and system for separating a fluid sample. The apparatus for separating a fluid sample may include a receiving chamber comprising a first opening and a second opening. The first open...
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WO/2023/183511A1 |
A single use, elongated tubular sleeve for a medical or dental instrument. The sleeve includes first through fifth layers. The second layer has a distal end and being formed from about 70% to about 90% of a linear low-density polyethylen...
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WO/2023/182997A1 |
A device includes at least one well to receive a polymerase chain reaction (PCR) mixture with the at least one well including dielectric first walls comprising a first thermal conductivity and a second wall. The second wall includes a fi...
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WO/2023/183657A1 |
Disclosed herein are methods and devices related to exponentially powered, multiplexed detection apparatus with mobile, portable, semi-quantitative features, also capable of being a key part of localized, centralized or immobilized diagn...
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WO/2023/179927A1 |
The invention relates to a microfluidic device for obtaining a homogeneous plasma-reagent mixture (100) comprising a collection module (110) for collecting blood plasma (102) arranged to passively separate the blood plasma from a sampled...
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WO/2023/182998A1 |
A device includes a well and a control portion. The well is to receive a polymerase chain reaction (PCR) mixture within an interior partially defined by a first wall, which comprise a heating first sheet. The control portion is to determ...
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WO/2023/183764A1 |
Embodiments of the present disclosure also relate to methods of fabricating flow cell substrates. Some exemplary workflows exploit orthogonal chemistries of substrate layers such that the process does not include polishing steps. Substra...
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WO/2023/181841A1 |
The present invention provides a disposable pipette with which it is possible to avoid mixing foreign matter into a sample. This disposable pipette (1) is for use in the medical field or the biochemical field, the disposable pipette (1) ...
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WO/2023/178671A1 |
The present disclosure provides a chip packaging structure and a chip packaging method. The structure comprises: a sample substrate, provided with a plurality of through holes passing through the sample substrate in the thickness directi...
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WO/2023/180161A2 |
In an example method, an initial depression is defined in a first resin layer of a multi-layer stack including the first resin layer over a second resin layer or a base support. The first resin layer is resistant to silanization in an or...
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WO/2023/183789A1 |
An automated diagnostic analysis system includes a plurality of modules for processing and analyzing biological samples, a sample transport system for transporting sample containers to and from each of the modules, and a system controlle...
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WO/2023/178432A1 |
Provided herein are digital microfluidic devices, methods and systems for improving absorbance and/or transmission detection in electromagnetic radiation spectroscopy. For example, devices and methods are provided for determining the abs...
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WO/2023/183327A1 |
The invention is directed to methods and systems for carrying out one or more highly multiplexed cellular assays. In some embodiments, one or more channels of a fluidic device are provided with photopolymerizable polymer precursors and c...
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WO/2023/180417A1 |
The invention relates to a microfluidic receiving element (110) for a microfluidic device (100) for processing fluids. The receiving element (110) has at least one recess (115) for receiving an aqueous solution, wherein the at least one ...
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WO/2023/179810A1 |
The invention relates to a centrifugal microfluidic biochip (10) with a fluidic system formed from a plurality of chambers and/or conduits with an opening (20) formed for introducing a biological sample into the fluidic system, character...
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WO/2023/183542A2 |
Artificial lyo-vials are provided that include a portion of a vial. The portion of the vial includes a vial wall with a top end opening and a bottom end opening. The bottom end opening includes an inside diameter that is greater than an ...
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WO/2023/180349A1 |
A reference electrode of an electrochemical sensor includes a substrate having internal walls defining a well and a channel. The reference electrode includes a conductive element disposed in the substrate. The well extends from a first s...
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WO/2023/180350A1 |
A reference electrode of an electrochemical sensor includes a substrate having well, a channel, and a conductive element therein. The well extends from a first surface of a substrate towards a second surface of the substrate. The channel...
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WO/2023/178416A1 |
Provided are paper-based microfluidic devices for measurement of cystatin C in a biological sample, such as blood or a blood fraction, and methods for fabricating such devices. Also provided are methods of detecting cystatin C in a biolo...
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WO/2023/180634A1 |
There is provided a microfluidic device, comprising: a plurality of chambers comprising at least two different molecular temperature probes, wherein i) at least one of the plurality of chambers comprises, in a same chamber, a first molec...
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WO/2023/180296A1 |
A capping and decapping device (2) for reversibly removing and mounting of a cap (5) to and from a tube (4) received in a tube seat (32) of a microplate (3) comprises a drum member (22) having a cap stamp (223), and a frame structure (21...
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WO/2023/179776A1 |
The present invention provides an automatic piston-gripping apparatus (100) and a pipette comprising the same. The automatic piston-gripping apparatus comprises a gripping mechanism (10), a holding shank (20), a first spring (30), and op...
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WO/2023/183397A1 |
One aspect of the present disclosure include a method and system for providing an interactive virtual reality simulation for virtual reality training. A headset, controllers, and/or one or more sensors communicate with a processor to dis...
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WO/2023/183554A1 |
A device is provided for performing an electrical assessment in a biological environment. The device includes a substrate having an exposed surface having holes. At least one of the holes includes surfaces coated with a conductive materi...
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WO/2023/180348A1 |
A reference electrode of an electrochemical sensor includes a substrate having a well, a channel, and a conductive element. The well extends from a first surface of a substrate towards a second surface of the substrate. The channel is wi...
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WO/2023/180422A1 |
A microfluidic device (105) comprises a pneumatic interface (205) for connecting the device (105) to an analysis device (100) and a fluidic channel system (210) with a plurality of fluidic micro-channels for transporting a fluid. The flu...
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WO/2023/182999A1 |
A device includes at least one well to receive a polymerase chain reaction (PCR) mixture and including an interior partially defined by a first wall comprising a heating first sheet. A control portion is to cause, via an electrical signa...
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WO/2023/174860A1 |
An aspect of the invention relates to a method for identifying an amino acid is proposed. The method comprises immobilising an amino acid on the surface of a FET sensor, acquiring a fingerprint of the immobilized amino acid, the acquisit...
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WO/2023/174208A1 |
A microfluidic chip (100) and a microfluidic system (200). The microfluidic chip (100) comprises: a substrate (110), an upper surface thereof being provided with a groove (111); a communication channel (112) provided in the substrate, on...
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WO/2023/175179A1 |
A method and system for determining droplet frequency of a flow of microfluidic droplets within a microfluidic droplet channel, comprising illuminating the flow of microfluidic droplets, using a beam splitter to split light from the flow...
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WO/2023/177853A1 |
The present invention provides a method for detecting an analyte in a liquid test sample. The detection method comprises mixing the test sample with a liquid enhancement composition to make a mixture, and contacting the mixture with a bi...
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WO/2023/177748A1 |
Improved sample cartridges, valve assemblies and methods of manufacture and assembly are provided herein. Such systems can include a sample processing cartridge having a unitary cartridge body with integral syringe tube and valve interfa...
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WO/2023/173277A1 |
The present disclosure provides a micro-fluidic chip and a use method therefor, and a micro-fluidic system. The micro-fluidic chip comprises: a substrate layer, the substrate layer comprising a base substrate and a driving electrode laye...
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WO/2023/174938A1 |
Provided herein are methods for the controlled filling of multiple reservoirs on a microfluidic device with a defined volume of fluid.
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WO/2023/178320A1 |
Automatable methods of horizontal co-culturing of cells using a single separation well microplate are provided. The disclosure also provides improved methods of quantifying secreted factors from cultivated cells, and methods for isolatin...
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WO/2023/174936A1 |
Provided herein are methods for the accurately controlled filling of a reservoir on a microfluidic device with a defined area of fluid.
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WO/2023/174823A1 |
A first aspect of the invention relates to a method for removing a terminal amino acid from a peptide. The method comprises providing a reaction cell configured as an electrochemical transducer translating an applied voltage or current i...
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WO/2023/175349A1 |
The present invention relates to a method of obtaining an image of a biological sample in a cuvette.
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WO/2023/175352A1 |
The present invention relates to a cuvette for analysing biological samples and a method of making a cuvette for analysing biological samples.
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WO/2023/177528A1 |
A microchannel includes a single inlet and a single outlet, a spiral section downstream from the single inlet, a straight section downstream from the spiral section, a detection section downstream from the straight section, and an expans...
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WO/2023/177694A1 |
Provided herein are vertical flow assay devices for detecting presence or an amount of cytokines in a sample. Also provided herein are immunoassay methods for detecting presence or an amount of cytokines in a sample, using the vertical f...
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WO/2023/173408A1 |
An apparatus and method for constructing a single-cell sequencing library in a microdroplet. The apparatus comprises a droplet generation chip, a droplet sorting chip, a droplet collection apparatus, and a droplet injection apparatus. A ...
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WO/2023/177876A1 |
Reagent cartridges and related systems and methods are disclosed. In accordance with an implementation, an apparatus includes a first flexible container, a second flexible container, and a coupling. The first flexible container has an en...
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WO/2023/177601A1 |
A microfabricated droplet dispensing structure is described, which may include a MEMS microfluidic fluidic valve, configured to open and close a microfluidic channel. The opening and closing of the valve may separate a target particle an...
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WO/2023/170258A1 |
An apparatus (500) for enzymatic synthesis of a plurality of polynucleotides, the apparatus (500) comprising a chiller (11) with a condensation generating device (8) and a condensation trap (1) comprising a frame with a front surface (2)...
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WO/2023/172490A1 |
A system that contains a camera and one or more reflecting elements is used to capture and to probe information from biologic and chemical samples. By placing a sample that is in a container between a camera and reflecting element, one c...
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WO/2023/170171A1 |
A method for the rearrangement and transfer of N separate biological samples from N separate first locations arranged in an irregular pattern to M separate second locations arranged in a regular pattern on a transfer device, said transfe...
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WO/2023/170153A1 |
The invention relates to a fluidic system with a fluidic element and a transport device. The fluidic element comprises a basic body and a deformable membrane, the basic body comprising at least one first channel and at least one second c...
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WO/2023/171888A1 |
The present invention provides a gene amplification and detection device using isothermal amplification and a lateral flow assay, wherein a target gene can be promptly and conveniently detected by using a combination of an isothermal app...
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WO/2023/170266A1 |
An apparatus (500) for enzymatic synthesis of a plurality of polynucleotides, the apparatus (500) comprising: a first of a plurality of well plates (502, 902, 804, 904, 806, 906) having a first number of reaction wells; a second of the p...
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