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WO/2023/216229A1 |
The present application provides a microfluidic chip and an application thereof. The microfluidic chip comprises a first chip channel layer, the first chip channel layer comprises a piezoelectric material, and the first chip channel laye...
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WO/2023/218375A1 |
A method for processing a sample in a container includes introducing the sample to the container. A cap is applied to the container. The cap contains a plurality of beads. The plurality of beads is mixed with the sample. The plurality of...
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WO/2023/216222A1 |
The present disclosure provides a microfluidic chip, a droplet generation device, and a method for controlling droplet generation size. The microfluidic chip comprises: a substrate and a first flow channel, a second flow channel, and a t...
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WO/2023/218373A1 |
A temperature regulation system for samples in a microplate includes a housing defining an interior volume and first and second airflow ports defined by a first and second exterior surfaces of the housing. The system includes an electrom...
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WO/2023/220055A1 |
An Integrated fully automated closed fluid handling system includes a set of fill-finish aseptic cartridges filled at least partially with a liquid or lyophilized and/ or dried, reagents, a microfluidic or fluidic conduit, a reusable or ...
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WO/2023/218018A1 |
The current invention relates to cell-cell interaction and in particular to cellular avidity. Provided are improved means and methods to study cell-cell interaction and characterizing cellular avidity. More in particular, the methods inv...
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WO/2023/216695A1 |
A multi-layer totally enclosed microfluidic chip, comprising: a base layer (1), a reaction layer (2), an adhesive layer (3), and a sample-adding layer (4), which are sequentially attached and fixed from bottom to top, wherein a press cap...
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WO/2023/215993A1 |
Provided herein are devices comprising: a bottom plate comprising one or more electrodes configured for performing droplet operations in a droplet operations gap formed between the bottom plate and a top plate, the top plate having a top...
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WO/2023/220517A1 |
An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechani...
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WO/2023/217310A1 |
A method for deparaffinizing formalin-fixed, paraffin-embedded tissue (FFPE) in a Centrifugal Microfluidic Biochip (10) with a fluidic system comprising a plurality of chambers (20), characterized by the steps of: a. placing formalin-fix...
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WO/2023/216361A1 |
A POCT microfluidic chip, a detection system, a detection method, and an application. The POCT microfluidic chip comprises an upper housing (10) and a lower housing (20), and further comprises: a sample pool (21), a liquid mixing pool (2...
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WO/2023/213822A1 |
The present invention relates to a fluid conduit device for merging a first liquid [101] with a second liquid [102].
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WO/2023/215490A1 |
Some systems, devices and methods detailed herein provide a restraint device for holding a microslide or another slide instrument in an operative position in a petri dish.
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WO/2023/214843A1 |
A nucleic acid detection cartridge according to the present invention comprises: a chamber body including a plurality of chambers provided on the upper surface; and a cover facing the upper surface of the chamber body, wherein at least o...
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WO/2023/215325A1 |
Described are systems, devices, and methods for delivery of a payload to a cell, including gene transfection of the cell. Such systems, devices, and methods are configured to capture and form a pore in a cell through which the payload ma...
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WO/2023/213912A1 |
A microfluidic device comprises a semi-permeable membrane, a first channel and a second channel. The first and second channels are provided on opposing sides of the membrane and in registration with each other. A first pump provides a fl...
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WO/2023/214873A1 |
Biodegradable and mouldable cassette for lateral flow assay device, and lateral flow assay device comprising said cassette A biodegradable and mouldable cassette for lateral flow assay device, and a lateral flow assay device comprising s...
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WO/2023/214874A1 |
A lateral flow assay device for in vitro diagnostics of a biological sample comprises a diagnostic test strip inserted into a cassette. The cassette comprises a lower cassette part and an opposite upper cassette part coupled to each othe...
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WO/2023/215298A1 |
Disclosed herein are methods for nuclear extraction and amplification using a bio-field programmable gate array. The method includes disposing a mixed droplet including one or more target nucleic acids adsorbed to magnetic beads on a mic...
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WO/2023/215820A1 |
Extracellular vesicles (EVs) have attracted enormous attention for their diagnostic and therapeutic potential. However, it has proven challenging to achieve the sensitivity to detect individual nanoscale EVs, the specificity to distingui...
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WO/2023/212776A1 |
A fluidic cartridge kit, including: a fluidic cartridge having an analysis portion and a sample reservoir sealed with a removable shipping closure to contain contents of the sample reservoir during transport; and a dispensing cap; wherei...
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WO/2023/209053A1 |
The invention relates to a device for trapping at least one cell pair in a solution containing at least one first cell (C1) of a first type and at least one second cell (C2) of a second type, comprising: - a microfluidic channel (3) adap...
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WO/2023/210944A1 |
Disclosed are a lateral flow assay strip for detecting drugs using a drug detection reagent, and a manufacturing method therefor. The lateral flow assay strip (10) for detecting drugs comprises: a sample pad (100) comprising a first poro...
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WO/2023/206092A1 |
A liquid transfer device (1), a multi-channel liquid transfer device (2), an automatic target object extraction and transfer device (3), a multi-channel automatic target object extraction and transfer device (4), and a nucleic acid extra...
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WO/2023/206096A1 |
A liquid transfer device (100) and a multi-path parallel liquid transfer device. The liquid transfer device (100) comprises: a liquid path valve plate (120), wherein the bottom of the liquid path valve plate (120) is provided with a valv...
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WO/2023/211398A1 |
The invention relates to a sterile and vacuumed urine container, which can be closed automatically after the patient completes the urination process with its self-covered structure, prevents the health personnel who will examine the urin...
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WO/2023/208448A1 |
The present invention provides for a single-use, disposable container and methods and apparatuses for testing liquid samples in a non-destructive fashion using the single-use, disposable container within a liquid sample analyzer. The sin...
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WO/2023/208375A1 |
Disclosed herein is a microfluidic device for analyzing a sample comprising one or more sample objects containing biological cells, a method of analyzing a sample comprising one or more sample objects containing biological cells using su...
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WO/2023/212084A1 |
Fibrotic diagnostic systems, subsystems, and components thereof are provided. A fibrotic diagnostic system can comprise a microfluidic device. The fibrotic diagnostic system can be preloaded with one or more components. For example, the ...
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WO/2022/246181A9 |
A sequencer for automated in situ sequencing of volumetric tissue samples is provided. In particular, an automated volumetric in situ sequencing device capable of operating on multiple samples in parallel is provided. Methods of fabricat...
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WO/2023/212290A1 |
Disclosed herein, inter alia, are devices, microplates, compositions, kits, and methods for interrogating biological samples.
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WO/2023/210966A1 |
One embodiment of the present invention provides an apparatus for separating a target object, the apparatus comprising: an injection unit into which a fluid containing fine particles is injected; a passage unit for making the target obje...
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WO/2023/211711A1 |
Aspects of the present disclosure are directed to a device configured to be inserted into a well plate. The device may include a main body having a top side and a bottom side, and a plurality of posts extending downwardly from the bottom...
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WO/2023/212336A1 |
Compositions and methods for isolating and detecting nucleic acid in a biological sample are provided. The compositions and methods utilize a modified solid support comprising an amine or amide group.
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WO/2023/212088A1 |
The disclosure provides a highly sensitive assay to detect the presence of a target analyte in a sample.
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WO/2023/212416A1 |
Disclosed herein are various bioreactor devices that mimic the mammalian joint. The bioreactor device includes a series of bioreactor chambers that contain different components of the joint, such as bone, cartilage, synovium, and ligamen...
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WO/2023/211901A1 |
A spiral inertial microfluidics device has been designed for use as a microfluidic sorting device. The device includes a spiral microchannel in which particles or cells of different sizes go through regions having different magnitudes of...
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WO/2023/202890A1 |
The invention relates to a system (10) for producing a mixture of fluids, comprising: - a pressure source (11), - a pressure regulator (12), - at least a first container (16.1) containing a first fluid (15.1) and a second container (16.2...
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WO/2023/202862A1 |
A fluidic module for use in a centrifugal microfluidic system comprises a fluid chamber having a first chamber region and a second chamber region, separated from each other by a dividing wall which extends radially inward with regard to ...
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WO/2023/201564A1 |
A microwell array chip, a use method therefor, and a detection apparatus. The microwell array chip comprises a microwell array substrate, and the microwell array substrate comprises a first main surface and a second main surface disposed...
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WO/2022/251508A9 |
A fluid processing cartridge includes a sample reaction chamber with a sample inlet port and a cap configured to selectively close the sample inlet port, a waste chamber, a rehydration buffer reservoir, and a reagent chamber. A plurality...
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WO/2023/202840A1 |
The invention relates to a microfluidic cartridge (1) for carrying out at least one processing step on a liquid sample, having: - a flat main part (2) which can be rotated about a rotational axis (3) and in which a microfluidic channel a...
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WO/2023/201942A1 |
Provided in the present invention are a single-cell sorting microfluidic chip and a single-cell sorting method. The chip comprises a cell supply tank, a micro-column array and a plurality of separately arranged capture units, wherein the...
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WO/2023/202368A1 |
Disclosed are a nucleic acid encapsulation and decapsulation method and a nucleic acid storage micro-fluidic chip. In a first aspect, provided is a nucleic acid encapsulation method. The encapsulation method comprises the following steps...
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WO/2023/201418A1 |
Provided is a microfluidic device for measurement of albumin and creatinine in a biological sample, such as urine, and methods for fabricating such devices. Also provided are methods of detecting albumin and creatinine and a ratio of alb...
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WO/2023/203339A1 |
A lateral flow test kit includes a cassette 2 and a swab 3. The cassette 2 comprises a vial 6 of liquid 54 closed by seal 22; a test strip 4; a passage 26 leading from the exterior of the cassette 2 to the vial 6; and a conduit 34 commun...
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WO/2023/205630A1 |
Devices to detect analytes (e.g., charged species such as ions) in samples are provided as are methods for their use. The devices comprise a tube or container comprising a water-immiscible sensing oil phase comprising at least one sensin...
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WO/2023/205519A1 |
A method for producing a microfluidic device, the method comprising: producing a first housing portion and a second housing portion; securing the second housing portion to the first housing portion; enclosing a three-dimensional biomater...
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WO/2018/160595A9 |
Systems, methods, and techniques for optofluidic analyte detection and analysis using multi-mode interference (MMI) waveguides are disclosed herein. In some embodiments, spatially and spectrally multiplexed optical detection of particles...
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WO/2023/203075A1 |
A microfluidic assembly is herewith disclosed comprising a micro- or nanofluidic chip for performing an analytical test, a housing for enclosing the chip, and a particularly-designed and functional cover for at least partially covering t...
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