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WO/2023/239688A1 |
Disclosed is a simple and cost-effective technique for generation of high-throughput aerosols of uniform-diameter submillimeter-size core-shell particles. An aerosol may be created by using, e.g., a first tube filled with liquid and havi...
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WO/2023/239730A1 |
Systems for reconstituting dried reagent compositions are provided. Aspects of the systems include a liquid container with an inner wall having a dried reagent composition and a solid volume displacer configured to be positioned inside o...
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WO/2023/239737A1 |
This application relates to an automation compatible collection device for use in collecting samples, e.g., biological fluids and other samples. In some embodiments, the collection device can include a capillary for collecting samples fr...
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WO/2023/237539A1 |
Disclosed is a system for testing a microfluidic sample chip for testing biological samples, in particular for PCR and/or fluorescence analysis, having the form of a hollow block comprising at least one chamber which is delimited by an u...
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WO/2023/236787A1 |
A centrifugal microfluidic analysis chip comprises a disc-structured substrate and a chip body which consists of cover plates bonded on the upper surface and the lower surface of the substrate; a rotation positioning hole which is provid...
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WO/2023/239895A1 |
The present disclosure provides for methods and systems for single-cell analysis. More particularly, the disclosure provides for methods and systems for analyzing cocultures of a single cancer-targeting cell (such as a T-cell) and one or...
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WO/2023/237698A1 |
The present invention relates to a microfluidic device for generating combinatorial spatially controllable diffusive gradients and methods for its manufacture. The present invention also relates to the uses of the microfluidic device of ...
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WO/2023/239374A1 |
A microfluidic die can include a fluid firing chamber and a microfluidic channel positioned to fluidically feed the fluid firing chamber. The fluid firing chamber and the microfluidic channel can be defined by a photoactive substrate hav...
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WO/2023/240079A1 |
A pipetting instrument for loading and dispensing a sample is described. The pipetting instrument includes an automated liquid pipettor having a deck for supporting a pipette tip box comprising pipette tips, and mandrels for engaging the...
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WO/2023/236313A1 |
The present invention relates to the technical field of nucleic acid detection. Disclosed is a microfluidic chip detection card box, comprising a housing (1), the housing (1) being provided with a functional chamber (2), a first flow cha...
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WO/2023/239377A1 |
Examples are directed to an apparatus include a digital microfluidic device (DMF) and circuitry. The DMF includes a housing including an interconnected chamber and with a two-dimensional array of electrodes couplable to the interconnecte...
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WO/2023/238132A1 |
A microfluidic device is disclosed which comprises: (i) a first surface (20) which comprises a plurality of reaction units (28), each reaction unit having a test chamber (12) connected to at least one opening (14) via a feeding capillary...
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WO/2023/239378A1 |
An example a digital microfluidic (DMF) device includes a housing including an interconnected chamber and with a two-dimensional array of electrodes couplable to the interconnected chamber, a plurality of reaction fluid wells fluidically...
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WO/2023/239375A1 |
A consumable microfluidic receptacle includes a first plate electrically connectable to a ground element and a second plate spaced apart from the first plate to define a passageway to receive a liquid droplet. The second plate includes a...
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WO/2023/237699A1 |
The present invention relates to a microfluidic device for generating combinatorial spatially controllable diffusive gradients and methods for its manufacture. The present invention also relates to the uses of the microfluidic device of ...
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WO/2023/233179A1 |
The present disclosure relates to means and devices for DNA analysis of the samples, in particular PCR (Polymerase Chain Reaction) analysis. The present disclosure comprises a plate for the analysis of a plurality of DNA samples. The pla...
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WO/2023/232813A1 |
The invention relates to a microfluidic device (100) comprising at least one sheath fluid inlet channel (1, 2) and a sample fluid inlet channel (3), and a common channel (4) configured to guide the sample fluid (20), with hydrodynamic fo...
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WO/2023/231236A1 |
The present application discloses a passive microfluidic microreactor (10) and a microfluidic chip. The passive microfluidic microreactor (10) comprises an inlet zone (200), a transition zone (500), a mixing zone (300), and a collection ...
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WO/2023/231158A1 |
A handheld nucleic acid testing device having a micro-fluidic chip, and a use method therefor, relating to the technical field of micro-fluidic chips. The handheld nucleic acid testing device having a micro-fluidic chip comprises: a samp...
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WO/2023/232662A1 |
The current invention relates to an improved microfluidic device for protein/protein complex purification, as well as an associated methodology and system. In particular it relates to systems and methods for electron microscopy, preferab...
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WO/2023/232799A1 |
An integrated photonic device for detecting molecules in a sample. The device comprises a sample- containment layer, optical structure, and detector which form a single integrated structure. The sample- containment layer is configured to...
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WO/2023/234465A1 |
The present invention relates to a diagnostic cartridge having improved flow of a solution, and more particularly, to a diagnostic cartridge having a structure capable of improving the efficiency and accuracy of a diagnosis using the dia...
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WO/2023/232849A1 |
The invention relates to a microfluidic flow cell intended for imaging a fluid, comprising a body which houses at least one fluid channel extending between a fluid inlet and a fluid outlet, wherein the at least one fluid channel comprise...
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WO/2023/234856A1 |
The present disclosure concerns a microfluidic method of assaying antibody secreting cells (ASCs), comprising the steps of isolating ASCs within droplets such that each droplet encapsulates only one ASC; iincubating the droplets of step ...
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WO/2023/231397A1 |
A polymer microsphere preparation apparatus (300) and method. The polymer microsphere preparation apparatus (300) comprises a microsphere generation assembly (200) and a collection container (10), wherein the microsphere generation assem...
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WO/2023/230986A1 |
A centrifugal tube (1), comprising: an outer tube (101), a cap body (102) sleeved outside the outer tuber (101) to seal the outer tube (101), and an inner tube (103) arranged in the outer tube (101). The inner tube (103) comprises an ope...
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WO/2023/233345A1 |
Nanopore-based scanning system including a probe structure comprising a nanopore; suction means configured to draw an end of a (bio)molecule inside the nanopore and inside the probe structure, single or multiple times; and displacement m...
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WO/2023/235850A1 |
Disclosed herein photopatterned hydrogels, hydrogel-based microfluidic devices, methods of making hydrogel-based microfluidic devices, and methods of using hydrogel-based microfluidic devices.
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WO/2023/229979A1 |
Provided herein are methods of isolating and expanding a population of tumor reactive lymphocytes (TRLs) from a fluid sample of a subject in need thereof. In some embodiments, methods of isolating and expanding a population of TRLs compr...
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WO/2023/229982A2 |
Provided herein are technologies for reducing fluid convection during processing and analysis of a biological sample. The provided technologies can include the use of a porous insert to limit fluid convection adjacent to a biological sam...
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WO/2023/227943A1 |
Aspects of the present invention relate to a microfluidic concentrator chip device including a microfluidic chip having a flat body with a top and bottom surface, a first end, a second end, and a length therebetween, a channel in the bod...
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WO/2023/227447A1 |
The present disclosure generally relates to digital microfluidic devices and associated methods. Some digital microfluidic devices described herein may be particularly suitable for manipulating droplets suitable for hosting cell growth. ...
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WO/2023/229599A1 |
An example one-time-open microfluidic valve can include an inlet microfluidic channel in a first elevation plane and an outlet channel in a second elevation plane. An upstream end of the outlet channel can overlap a downstream end of the...
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WO/2023/227834A1 |
Disclosed is a cell culture apparatus and a method. The apparatus comprises one or more cell culture modules. The one or more cell culture modules comprise a first culture medium reservoir, a second culture medium reservoir, a first open...
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WO/2023/230597A1 |
Featured is a device for encapsulating cells and aggregates thereof. Also featured are methods of encapsulating aggregates including, e.g., parenchymal cells (e.g., hepatocytes) and stromal cells, in a biocompatible scaffold.
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WO/2023/227493A1 |
The invention relates to a device for capturing a biological object (O), which device comprises a first fluid circuit (C1) having: - a first fluid inlet (A1) and a second fluid inlet (A2), - a main channel extending between the first flu...
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WO/2023/227891A1 |
A pipetting head (100) for a liquid dispensing apparatus (10) for use with an array of removable pipettes (1010) is provided. The pipetting head has a pipette body mounting assembly (120) for holding the pipette bodies (1100) of the remo...
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WO/2023/225310A1 |
A syringe for withdrawing an aspirate from a body for micro fat grafting includes a barrel having a first barrel portion with an inner wall with a lesser diameter than an inner wall of a second portion. A filter for separating fat cells ...
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WO/2023/225106A1 |
Systems and methods for automated digital polymerase chain reaction are described herein. A method of performing automated digital Polymerase Chain Reaction (PCR) can include receiving a sample in a sample tube within a sample tube holde...
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WO/2023/225048A1 |
A system for processing cells can be provided. The system can include a control board, a gas source fluidly coupled to the control board, a process board that is engageable with the control board to fluidly couple the process board to th...
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WO/2023/222773A1 |
A device for particle isolation comprises a reservoir to contain a liquid including particles and a channel with an inlet and an outlet. The inlet is configured to be fluidically coupled to the reservoir containing the liquid including p...
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WO/2023/222631A1 |
The invention relates to a microfluidic chip (1) for growing cells comprising a reservoir (2) capable of containing a solution, at least two separate chambers (3) capable of being supplied with the solution from the reservoir and capable...
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WO/2023/224993A1 |
Examples are directed to rapid detection test (RDT) devices, apparatuses, and method of forming RDT device and/or apparatuses that include substrates functionalized with a coupling agent. An example RDT apparatus comprises a substrate at...
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WO/2023/225065A1 |
The technology relates in part to a device and associated methodology useful for accurately and precisely measuring fluid volume dispensed from a fluid dispenser device, and in certain applications, volume dispensed from a multichannel f...
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WO/2023/222728A1 |
The present invention relates to a system for rapid analysis of a biological sample intended for detecting the presence of at least one analyte in the biological sample. The rapid analysis device (1) comprises a housing (2) and a cap (8)...
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WO/2023/225100A1 |
A microfluidic chip comprising: a first port; a first microchannel having a first end connected to the first port and having a first portion with a spiral path around the first port; a membrane; and a second microchannel having a spiral ...
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WO/2023/221124A1 |
A microfluidic chip (1000, 3000, 4000, 5000, 6000), a method for controlling the flow velocity of a fluid in the microfluidic chip (1000, 3000, 4000, 5000, 6000), and a use method for the microfluidic chip (1000, 3000, 4000, 5000, 6000)....
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WO/2023/221960A1 |
The present disclosure provides a microfluidic device, a system, a kit, a method of analyzing nucleic acids, a method of manipulating nucleic acids, a method of detecting a biomolecule, and a method of analyzing a biomolecule. The microf...
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WO/2023/220196A1 |
Methods and systems are provided for a microfluidic electrowetting array device that is integrated. for material transfer with a second chip device. The integration for material transfer is configured to transfer one or more materials se...
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WO/2023/220250A1 |
A cooling device suitable for cooling paraffin tissue blocks with little or no moisture artefacts, as well as the use thereof to obtain good quality serial sections for microscope slides. The slides can be used in histology and anatomica...
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