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WO/2022/162018A1 |
The invention relates to processes for purification of poly-tagged products, such as mRNA, from synthetic or biological compositions. The process involves contacting the composition with a oligo d (T)-functionalized chromatography medium...
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WO/2022/164442A1 |
A module for removing a VOC from a 3D printing apparatus comprises an absorption element. The absorption element comprises a condensation coil and a packing material; an inlet which routes VOC vapour and water vapour from a powder bed us...
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WO/2022/155659A1 |
A method of removing water from a mixture of iodine (I2) and water includes providing a mixture comprising iodine and water and: contacting the mixture with an adsorbent to selectively adsorb water from the mixture, contacting the mixtur...
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WO/2022/149090A1 |
Provided is a method for the production of refined, low-acetal ethanol, comprising providing a fermentation product produced by fermentation of a carbon source with an ethanol-producing organism, which fermentation product comprises betw...
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WO/2022/146083A1 |
The present invention relates to a composition and chromatography column for separating a high-purity exosome, and an exosome separation method using same. The present invention provides information on the pH, ion concentration condition...
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WO/2022/137076A1 |
The present disclosure provides methods for purifying a recombinant AAV (rAAV) vector from a solution by affinity chromatography to produce an eluate enriched for AAV vectors (rAAV vectors).
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WO/2022/136459A1 |
The present invention relates to a chromatographic material comprising a polymer network material-based self-supporting bi-continuous separation matrix for adsorptive material separation in liquid media, and a method of producing the chr...
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WO/2022/137206A1 |
This disclosure relates to a method/system for associating at least one target molecule with a molecularly imprinted polymer and/or a method/system of obtaining at least one target molecule from a source material. More particularly, this...
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WO/2022/133772A1 |
It relates to the medicinal chemistry field, particularly to a process for separating the isomeric compounds comprising a ring-opened thiosuccinimide group and a chiral moiety.
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WO/2022/136401A1 |
The invention provides a HPLC equipment comprising a preparative RP-HPLC column (1) and a back-pressure valve (V3) which is connected downstream the HPLC column (1). The invention also provides a process for separating a component of int...
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WO/2022/139398A1 |
The present invention relates to a method of producing and refining carrier-free lutetium-177 using chromatography, and more specifically to a method of producing and refining carrier-free lutetium 1-77 using chromatography having excell...
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WO/2022/130172A1 |
Chromatographic method for separation of AAV capsid proteins using hydrophilic-interaction chromatography (HILIC). The method provides the ability to quantify capsid protein ratio and to separate capsid proteins to the extent that low le...
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WO/2022/130322A1 |
The present invention concerns a method for separating different oligosaccharides having at least one carboxylic acid group, also referred to as charged oligosaccharides. The method allows for the high throughput separation of oligosacch...
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WO/2022/125966A1 |
A method of removing THC and/or THCA from a mixture, the mixture including THC and/or THCA and at least one cannabinoid is provided. The method comprises passing a first feedstock stream through a first chromatographic resin arranged in ...
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WO/2022/120494A1 |
Sorbent compounds useful in the extraction of lithium from liquid sources such as brines (naturally occurring and synthesized), leachate solutions from the leaching of minerals or recycled materials, and others are described. The sorbent...
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WO/2022/123240A1 |
This invention provides a method of purifying or isolating a heterologous protein or polypeptide comprising: (a) providing a sample containing the protein or polypeptide covalently or non- covalently attached to a magnetic nanoparticle b...
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WO/2022/122399A1 |
A layer structure is suggested comprising a solid substrate having a surface, the surface carrying a layer comprising a molecularly imprinted polymer, wherein the molecularly imprinted polymer is adapted to bind a glyphosate analyte, whe...
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WO/2022/121989A1 |
A method for recovering lithium from a lithium precipitation mother liquor, the method using the following cycle steps including adsorption, displacement, desorption and transformation: a. mounting a lithium-sodium separation resin in a ...
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WO/2022/126115A1 |
A chromatography system includes a first chromatography column and a panel having a top face and an opposing bottom face, a first cavity being formed on the panel so as to pass through the top face and be encircled by an inner surface. T...
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WO/2022/126028A1 |
The present disclosure relates to methods, systems, and apparatus for efficient continuous production of hydrophobic products with the simultaneous retention of substrates.
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WO/2022/125684A1 |
Embodiments of a method of purifying a lysophosphatidylcholine (e.g., LPC-DHA and/or LPC-EPA) from a composition containing the lysophosphatidylcholine and at least one impurity, e.g., from phospholipids, free fatty acids, triacylglycero...
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WO/2022/125088A1 |
A terpene extraction system and method for efficiently extracting valuable terpenes from biological material, such as hemp. The terpene extraction system and method generally includes a fluid-bed mixer having a vessel, wherein the vessel...
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WO/2022/119712A2 |
A method for clarifying a bioprocess fluid comprising particles suspending in a cell culture fluid is provided. The method includes providing a cell culture suspended in an unclarified bioprocess fluid in a bioreactor. A chromatography a...
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WO/2022/117773A1 |
The invention relates to upstream and/or downstream processes of selectively reducing one or more unpaired cysteines of a monoclonal antibody, whilst keeping conserved inter- and intra- molecular disulfide bonds elsewhere in the antibody...
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WO/2022/111916A1 |
The present invention discloses a method for extracting cannabidiol from dried, milled and decarboxylated hemp by submitting to a subcritical liquid carbon dioxide extraction followed by a mild liquid carbon dioxide separation.
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WO/2022/114921A1 |
The present invention relates to: a method for removing a Bordetella-pertussis-derived endotoxin in a multivalent mixed vaccine, comprising a pre-adsorption step that is prior to a step of mixing an inactivated Bordetella pertussis vacci...
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WO/2022/111997A1 |
The invention relates to an alkali-stable mutated Fc-binding Protein A domain, having at least 95% identity to SEQ ID NO: 8 or SEQ ID NO: 9.
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WO/2022/106480A1 |
The present invention relates to an apparatus (200) for bio-product processing. The apparatus (200) comprise a processing column (201) comprising an upper column tube (202B) releasably coupled to a lower column tube (202A). The lower col...
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WO/2022/109280A1 |
Provided is a system, process, and method for the recycling of waste plastics. The recycling system, process, and method may comprise sorting of comingled waste. The sorting of comingled waste may include sorting into, for example, like ...
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WO/2022/100325A1 |
Disclosed is an optimization method for capturing proteins by multi-column continuous flow chromatography, comprising the following steps: step 1, under the conditions of set sample loading protein concentration and arbitrary sample load...
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WO/2022/101499A1 |
In a method for ensuring microbiological purity of a single-use device (10) for carrying out a biotechnological process, the single-use device (10) comprises at least one gamma-sterilisable component, which is formed from materials suita...
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WO/2022/103806A1 |
Disclosed herein are static mixer assemblies, and related methods of fabrication and use. The disclosure provides advantageous static mixer assemblies, and improved systems/methods for utilizing and/or fabricating the static mixer assemb...
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WO/2022/096499A1 |
A chromatographic method for separation of lipid-membrane-enclosed compound assemblages (LMCAs) from chromatin heteroaggregates including degraded remnants from LMCAs in a sample, - contacting the sample with a chromatographic material w...
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WO/2022/098894A1 |
Provided herein is a platelet-rich plasma (PRP) product comprising activated PRP releasate in which a deleterious factor that inhibits growth of a target tissue type is removed. The PRP product is useful in growth or regeneration of tiss...
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WO/2022/087738A1 |
A process for the removal of anionic radionuclides from spent ion exchange resin comprising mixing at least one reagent with said resin in solution to form a first mixture, and removing the anionic radionuclides from the spent ion exchan...
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WO/2022/090450A1 |
The present invention relates to a process for the purification of an acidic human milk oligosaccharide (HMO) from a fermentation broth using ion exchange methods. This process allows for a reduction of the number and/or extent of desalt...
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WO/2022/090242A1 |
The subject matter of the present invention consists of formo-phenolic resins, a process for the preparation thereof, and the use of same in the extraction of uranium from an aqueous sample. The present invention also relates to novel fo...
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WO/2022/094116A1 |
The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step and/or a MM-HIC/ IEX chromatography step, and are useful for providing a method of reducing ...
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WO/2022/093989A1 |
A method, system, and apparatus for chromatography comprises a chromatographic system can include a column packed with mesoporous graphitized carbon (MGC). The MGC serves as an ideal stationary phase and facilitates the efficient isomeri...
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WO/2022/086526A1 |
The method and materials of this invention make possible improved and faster techniques for organic-aqueous extractions and chemical reaction workups. The improved specialized sponge, coated or uncoated, with various pore sizes, extracts...
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WO/2022/082320A1 |
A psychoactive alkaloid source is used to obtain a psychoactive alkaloid extract. The source may be psychedelic mushrooms, animals or plants or a prior extract therefrom. Psychoactive alkaloids in the extract are adsorbed onto an adsorbe...
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WO/2022/083799A1 |
An immobilized metal ion affinity chromatographic packing, a chromatographic column, and a preparation method therefor. Potassium sodium silicate, gamma-glycidoxypropyltrimethoxysilane and water-dissolved adenosine triphosphate disodium ...
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WO/2022/082327A1 |
The present invention relates to a method for separating and purifying melittin (Mn), apamin (Ap), mast cell degranulation (MCD) peptide and other components present in bee venom (BV). The method allows the beneficial components of the v...
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WO/2022/061418A9 |
A method for producing a porous copolymer monolith substrate for use in flow through liquid chromatography applications is disclosed. The method comprises forming a reaction composition comprising at least one monoethylenically unsaturat...
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WO/2022/079492A1 |
Devices and methods for portable, modular production of a biological material comprising a device compatible with receiving one or more cartridges, wherein production and purification of the biological material are handled inside the car...
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WO/2022/079696A1 |
A method of optimizing a design parameter for an adsorption column includes developing a first kinetic model and a Linear Driving Force model for a chromatography and ion exchange based adsorption process. Both analytical solutions to th...
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WO/2022/077128A1 |
The present invention describes a new device for extracting and purifying nucleic acids from a biological sample, which comprises: a closed container that holds a solid phase comprising a mixture of non-ionic resins, preferably aromatic ...
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WO/2022/077606A1 |
A bonded amylose derivative having a structure represented by formula (I), and a preparation method therefor and an application thereof. Starch is immobilized on silica gel in a chemical bonding mode to form a chromatographic column stat...
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WO/2022/079695A1 |
The present disclosure is directed to a coating process for chromatographic surfaces. Embodiments of the present disclosure feature a two-step, vapor-liquid phase organosilane deposition method for creating a hydrophilic, non-ionic surfa...
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WO/2022/081818A1 |
The present disclosure provides advantageous porous assemblies, and improved systems and methods for utilizing and/or fabricating the porous assemblies. More particularly, the present disclosure provides porous assemblies fabricated at l...
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