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WO/2024/044090A1 |
The invention is directed to a valve switching system for selectively interconnecting components of a bioprocess installation (2), comprising a valve switching cassette (15) and an actuator block (16). It is proposed, that the valve swit...
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WO/2024/042249A1 |
What is described is a process for producing decaffeinated raw coffee beans. One process step comprises the extraction of caffeine from raw coffee beans by means of an aqueous extraction liquid, a further process step the binding of caff...
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WO/2024/043296A1 |
An amine separation method comprises a separation step for separating an amine through chromatography using: a stationary phase obtained by supporting, on a carrier, a ligand having a crown ether-like cyclic structure; and a mobile phase...
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WO/2024/042739A1 |
A liquid immersion cooling system for cooling a heat generator provided to a substrate, the cooling system comprising: a cooler main body including a casing which accommodates the substrate and the heat generator inside and in which a re...
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WO/2024/042372A1 |
The present disclosure pertains to non-porous composite particles that are non-porous, polymer-based particles. In various embodiments, a non-porous polymer core is surface modified. In various embodiments, a non-porous hybrid organic-in...
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WO/2024/042371A1 |
The present disclosure pertains to non-porous composite particles that are non-porous, polymer-based, organic-inorganic materials. In various embodiments, a non-porous polymer core is surface modified. In various embodiments, a non-porou...
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WO/2024/038432A1 |
The present invention in some embodiments thereof relates to an apheresis device for collecting and/or removing substances from the blood, such as, circulating tumor cells (CTCs), selected proteins, lipids, pathogens, various harmful sub...
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WO/2024/036251A1 |
Provided are methods of separating full capsid particles and empty capsid particles in a viral capsid preparation by overloading viral capsid preparations onto an anion exchange medium integrated with weak partitioning chromatography and...
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WO/2024/028498A1 |
The present invention pertains to a chromatography method for the purification and/or separation of target nanoparticles. Said method relies on a hydrophilic stationary phase that comprises rigid beads with throughpores, making these bea...
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WO/2024/027080A1 |
An adsorption resin column device, comprising: a vessel body (1), a partition plate (2), a first resin structure (3) and a second resin structure (4). The vessel body (1) is provided with a first circulation port (11) and a second circul...
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WO/2024/028225A1 |
The invention relates to an ion exchange material for use as a stationary phase in an analytical or preparative separation process, in particular for the separation of anions, preferably halo acetic acids. The material comprises - a poly...
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WO/2024/030509A1 |
Disclosed herein are embodiments of matrixes made of a porous size exclusion support and a cationic moiety for separating one or more small molecules from one or more large molecules in a sample using differences in one or more propertie...
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WO/2024/029394A1 |
The present invention provides a carrier which is for chromatography, which has a large dynamic binding capacity with respect to an antibody or a fragment thereof, and through which a protein ligand is unlikely to leak even when the carr...
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WO/2024/023265A2 |
It is provided a purification processe for removing impurities, such as GroEL, from samples of outer membrane vesicles (OMVs). For example, the process is applied to OMVs derived from Bordetella or from Neisseria, for example Neisseria g...
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WO/2024/026446A1 |
The present application relates to systems and methods for purifying polypeptides, such as His-tagged polypeptides, using immobilized metal chelate affinity chromatography (IMAC). The method includes loading a composition comprising the ...
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WO/2024/022894A1 |
The present disclosure relates to a process for recovery of a nucleic acid product from a composition. The process (100) comprising: (i) contacting (110) the composition with a chromatography material functionalised with a ligand. The ch...
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WO/2024/025404A1 |
The invention consists in recycling and then purifying, by means of a closed-loop cascade of nanofiltrations, sulphuric acid for regenerating ion-exchange resin, and thus concentrating the uranium initially contained therein with a view ...
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WO/2024/020596A1 |
Fusion proteins, comprising at least one single chain antibody fragment (scFV), and a cancer antigen or marker, or a fragment thereof are provided. The scFV is capable of selectively binding to a cytokine released by chimeric antigen rec...
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WO/2024/020314A1 |
The present disclosure relates to methods of detecting and purifying EVs (e.g., exosomes) present within a sample using monolithic anionic exchange chromatography and light scattering. Such methods allow for a more accurate and high-thro...
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WO/2024/012042A1 |
A method for regenerating an alkanolamine solution. The method comprises the following steps: subjecting an alkanolamine solution to be regenerated to a first adsorption treatment by using a hydrogen phosphate removal agent so as to obta...
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WO/2024/010617A1 |
Systems and methods for treating water containing PFAS are disclosed. Adsorption media may be used to remove PFAS from water. Supercritical carbon dioxide (sCO2) may be used to release PFAS from loaded adsorption media to form an extract...
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WO/2024/008256A1 |
The present invention relates to an improved apparatus and process for separation of compounds from a biological composition by means of a dynamic layer of sorption material.
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WO/2024/009551A1 |
This method for regenerating used turbine oil comprises: a contact step for bringing a used turbine oil into contact with an adsorbent; and an addition step for adding an additive to the used turbine oil obtained after the contact step. ...
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WO/2024/003141A1 |
The present invention relates to tangential flow filtration/chromatography systems, the use thereof, and methods of separation, particularly simultaneously separating one or more target molecules from cells, cell debris and further conta...
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WO/2023/086771A9 |
Capture membranes for lanthanide metal ions can be made from fusion proteins having at least one lanthanide metal binding sequence (SEQ ID NO: 1-4) covalently bound to a silk-elastin- like polymer (SELP). Capture membranes can be made fr...
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WO/2024/006121A1 |
The present disclosure describes a computer implemented method, a system, and a computer program product of controlling the purification of a macromolecule solution via real-time multi-angle light scattering.
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WO/2023/248025A1 |
A process of recovering lithium from a brine containing lithium. The process comprises: providing the brine to a lithium-selective sorbent for adsorbing the lithium to the lithium-selective sorbent; eluting the lithium from the lithium-s...
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WO/2023/247468A2 |
The present invention relates to isolation and separation of kappa light chain-containing proteins. More specifically it relates to a separation matrix comprising kappa light chain-binding ligands covalently coupled to a porous support, ...
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WO/2023/247280A1 |
Disclosed is a microfluidic system having a housing and having at least one flow channel (20) formed within the housing, wherein at least one element (40) that has an ion exchanger mixed-bed resin is arranged in at least one sub-region o...
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WO/2023/250411A1 |
A filter plate device has an inlet and an outlet where the filter plate has a polymeric framework having a filtration zone and a membrane bed of one or more membranes bonded and sealed to the polymeric framework in said filtration zone w...
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WO/2023/247974A1 |
A purification receptacle for the chromatographic purification of a liquid. The purification receptacle comprises a seat and a chromatographic media assembly including a chromatographic membrane to which target components contained in a ...
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WO/2023/250142A1 |
Methods and systems directed to the separation of tritium from an aqueous stream are described. The separation method is a multistage method that includes a purification stage during which tritium of a tritium-contaminated aqueous stream...
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WO/2023/250070A1 |
Methods of purification for the large scale synthesis of CB[7]-PEG may include at least one of diafiltration or tangential flow filtration, column chromatography, affinity "pull-down" techniques, or selective precipitation methods. In on...
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WO/2023/242184A1 |
The invention relates to a method for the purification of a neutral or sialylated human milk oligosaccharide (HMO) from a fermentation broth. Moreover, the invention also concerns neutral or sialylated HMOs obtained by the inventive meth...
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WO/2023/244606A1 |
A waste extraction system includes a precipitation tank comprising a waste stream input, a solution input, and a waste stream output, wherein the waste stream input is fluidly coupled to an upstream segment of a main waste pathway, a col...
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WO/2023/242475A1 |
A hardwood-derived carbohydrate composition comprising monomeric sugars in an amount of 75 - 98 weight-% based on the total dry matter content of the carbohydrate composition, wherein the monomeric sugars include monomeric xylose, the am...
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WO/2023/242473A1 |
A hardwood-derived carbohydrate composition comprising 75 - 97 weight-% monomeric sugars is disclosed. The monomeric sugars include 55 – 75 weight-% of monomeric xylose. The carbonyl content of the carbohydrate composition is 4000 – ...
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WO/2023/244389A1 |
A feed mixture comprising one or more xylene isomers and C9+ aromatic hydrocarbons may be separated in a first distillation column to obtain a first overhead stream comprising m-xylene and/or p-xylene and a first bottoms stream comprisin...
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WO/2023/244765A1 |
Provided herein are methods of quantifying or identifying two or more peptides or polypeptides, methods of quantifying or identifying two or more chemically isotopic labeled peptides or polypeptides, and methods for obtaining a plurality...
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WO/2023/244394A1 |
A feed mixture comprising one or more xylene isomers may be separated in a p-xylene recovery unit using simulated moving bed. chromatography with toluene as a desorbent to obtain a product stream rich in p-xylene and a raffinate stream l...
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WO/2023/245206A1 |
An oral sorbent composition and method for use in removing multiple toxins of kidney failure from the gut. The oral sorbent composition having a gas permeable membrane or coating around a sorbent component that would remove small and cha...
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WO/2023/242474A1 |
A hardwood-derived carbohydrate composition comprising monomeric sugars in an amount of 65 - 85 weight-% based on the total dry matter content of the carbohydrate composition is disclosed. The monomeric sugars include monomeric xylose, t...
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WO/2023/240322A1 |
The present invention pertains to the purification of soluble complement receptor proteins and variants thereof by hydrophobic interaction chromatography (HIC) using a chromatographic material with a particle size of less than 60 µm.
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WO/2023/242546A1 |
There is described an apparatus (100) for separating hydrogen isotopes from exhaust gas of a fusion power system. The apparatus 100 comprises an inlet (111) configured to receive a gas comprising a mixture of isotopes; a distribution uni...
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WO/2023/242194A1 |
The invention relates to a method for the purification of a neutral or sialylated human milk oligosaccharide (HMO) from a fermentation broth. Moreover, the invention also concerns neutral or sialylated HMOs obtained by the inventive meth...
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WO/2023/242476A1 |
A hardwood-derived carbohydrate composition comprising 88 – 99.75 weight-% monomeric sugars is disclosed. The monomeric sugars include 55 – 85 weight-% of monomeric xylose. The carbonyl content of the carbohydrate composition is 10 -...
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WO/2023/242412A1 |
The present invention relates to a filter system, which can be used as a clarification filter/depth filter for cell culture clarification before chromatography and/or ultrafiltration for protein purification, as well as to a method of se...
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WO/2023/239680A1 |
A solid-liquid separation system configured to produce a filtrate includes an inlet zone configured to receive a solid-liquid slurry; a filter including a dynamic membrane, the dynamic membrane including a liquid-permeable supporting ele...
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WO/2023/236488A1 |
The present application relates to a chromatography medium and a chromatography device comprising same. The chromatography medium at least partially consists of a polymer material formed by crosslinking an at least partially crosslinkabl...
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WO/2023/237030A1 |
An ultrafine powder of a food emulsifying agent, the use of the ultrafine powder of the food emulsifying agent in the preparation of a long-shelf-life food-grade tableware cleaning powder, and a preparation method therefor. In order to s...
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