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WO/2024/092300A1 |
The present disclosure relates to methods for differentiating mesenchymal stem cells (MSCs) towards an osteogenic lineage using daily short exposure to acoustic wave energy at a frequency greater than 1MHz. Methods disclosed herein can b...
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WO/2024/092321A1 |
The present disclosure relates to methods for modifying endothelial barrier function and cellular organisation through exposure to acoustic wave energy. In vitro models of endothelial barrier function and cellular organisation and method...
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WO/2024/066115A1 |
Disclosed are a method for enhancing the anti-tumor function of a T lymphocyte and use. The method comprises the step of culturing a T lymphocyte under a physical electrical stimulation condition, wherein the T lymphocyte comprises an in...
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WO/2024/054842A1 |
An apparatus and methods for electroporation of cells are disclosed. The apparatus comprises a memory storing instructions, a high voltage module to apply a voltage to cells, a low voltage module including a user interface, a system boar...
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WO/2024/040805A1 |
Provided are a nano material for generating ATP and NADPH under red light excitation and a method for preparing the nano material. By means of extracting and nanosizing a plant-derived thylakoid, a nano thylakoid is obtained to generate ...
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WO/2024/041201A1 |
Provided are a flow electroporation apparatus and a control method therefor. The control method comprises: starting a first electrode assembly at a first moment, forming an electric field in an electroporation chamber of the first electr...
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WO/2024/041200A1 |
Disclosed is a flow electroporation assembly, comprising a main liquid inlet, a main liquid outlet, a connecting pipeline, and at least two groups of electrode assemblies. Each group of electrode assemblies comprises two planar electrode...
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WO/2024/035147A1 |
The present invention relates to: an Lgr4 gene promoter or a fragment thereof regulated by electromagnetic waves; a vector comprising same; a composition for regulating gene expression by electromagnetic waves, the composition comprising...
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WO/2024/028532A1 |
The present invention relates to a thermoelectric device for measuring stress in photosynthetic organisms (11), stress which is caused by high and/or low temperatures, ultraviolet (UV) radiation and/or high photosynthetically active radi...
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WO/2024/028150A1 |
The present invention relates to a device (1) and its use for receiving a single-use container (44), comprising a receiving container (10) having an interior wall (16) that delimits a container interior of the receiving container (10) fo...
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WO/2024/025586A1 |
A feedback system (10) and method (30) that identifies characteristics (23, 25) of one or more cells (56) being grown on a metasurface (62) and utilizes the characteristics to initiate (35) and adjust (40) a field applied to the metasurf...
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WO/2024/020424A1 |
A bioengineered human tissue platform that allows quantitative studies of the effects of radiation, and cryoinjury on engineered cardiac tissue and engineered bone marrow.
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WO/2024/011248A1 |
Compositions and articles comprising scleroglucan that can be used for culturing and enumerating microorganisms even after exposure to sterilizing doses of radiation. The compositions also include one or more water swellable polymers oth...
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WO/2023/248085A1 |
Systems and methods are disclosed for inducing apoptosis and treating or reducing the occurrence of at least one condition, disease, disorder, or infection in a subject. The systems and methods rely on the application of an alternating e...
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WO/2023/240336A1 |
Systems and methods for growing cells or cell sheets are described. The method may use biocompatible or food-safe materials. The method may allow for cell alignment, optionally in selected patterns, which may be produced by casting a mem...
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WO/2023/239061A1 |
The present invention relates to a method for recovering metals from a waste battery by using a magnetic field-applied biological leaching process. According to the method of the present invention, by applying a magnetic field to the bio...
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WO/2023/227085A1 |
The invention relates to a cancer-specific T cell preparation method based on peripheral blood or peripheral immune organs for preventing or treating cancer. The preparation method specifically comprises: first, separating to obtain peri...
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WO/2023/221853A1 |
Disclosed in the present invention are a method for constructing a senescent cell and a method for evaluating the anti-senescence efficacy. The method for constructing the senescent cell comprises: performing seeding culture and subcultu...
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WO/2023/216227A1 |
Provided are a method for preparing a microbial microcapsule and a method for synthesizing a microbial flora (particularly a cross-species microbial flora). According to the principle that chitosan and sodium tripolyphosphate are subject...
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WO/2023/202608A1 |
The present application relates to the technical field of biology, in particular to a beauveria bassiana strain with high ultraviolet radiation resistance as well as a directional mutagenesis method therefor and use thereof. The beauveri...
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WO/2023/191559A1 |
The present invention relates to a method for mass proliferation of activated natural killer cells, and a use thereof. More specifically, provided is a method for inducing, differentiating, and mass-proliferating activated natural killer...
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WO/2023/152026A1 |
Process of making a mycelium based material in a mould. Electrical stimulation is used to control growth of the mycelium, in particular to stimulate mycelium growth during colonization of the substrate and/or to inhibit further growth in...
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WO/2023/142201A1 |
A method for the industrial production of a vaccine against Pseudomonas aeruginosa. By using a series of standardized, programmed and digital settings, it is ensured that a vaccine with stable quality containing whole Pseudomonas aerugin...
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WO/2023/147487A1 |
The present disclosure relates generally to high-frequency ultrasonicator devices, and more specifically to high-frequency ultrasonicator devices for disrupting or lysing cells, and methods for using those devices.
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WO/2023/141544A1 |
A method and system is provided for increasing lipids, biomass, and metabolite yields of a microalgae culture of cells and other organisms with conserved metabolic pathways compared to an untreated culture or organism when maintained und...
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WO/2023/126880A1 |
A method for morphologically altering and inhibiting the bacterial and viral functions is carried out by generating a magnetic field controlled by an operating signal ( C ) at a frequency comprised between 30 kHz and 300 kHz or comprisin...
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WO/2023/110063A1 |
The present invention relates an apparatus (1) and its use for in-vitro influencing biological cellular material by applying electric and/or electromagnetic emissions to the biological cellular material The apparatus (1) comprises a carr...
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WO/2023/108230A1 |
An apparatus for use in promoting motility of flagellar cells, comprising an acoustic energy emission module configured to generate ultrasound energy, the module being configured to generate ultrasound waves within a frequency range of a...
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WO/2023/114011A1 |
The present invention includes non-invasive methods of treating aging using low frequency structured and modulated ultrasound. The ultrasound irradiation causes mechanical stretching of cells even within the body of an organism which in ...
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WO/2023/100712A1 |
This light irradiation apparatus comprises an irradiation unit capable of irradiating an irradiation target with irradiation light having a radiation illuminance of 5 mW/cm2 or more in the wavelength range of 380 nm to 420 nm inclusive t...
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WO/2023/101369A1 |
The present invention relates to an islet-like organoid in which insulin secretion can be optically regulated by differentiating, into pancreatic islets, human pluripotent stem cells (monSTIM1-hPSC) obtained by knocking-in monSTIM1, whic...
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WO/2023/094503A1 |
The invention is directed to a process to convert carbon dioxide to methane by contacting an aqueous solution comprising dissolved carbon dioxide with an electron charged packed bed comprising of a carrier and a biofilm of microorganisms...
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WO/2023/085710A1 |
The present invention relates to a method for increasing the production of extracellular vesicles in a strain of the genus Lactobacillus, the method comprising a step for irradiating the strain with a red LED. According to the present in...
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WO/2023/079905A1 |
Provided is a cell peeling device that can efficiently peel cells that have uneven adhesion due to cell culturing conditions, peeling same in a non-contact manner from a culture container. This cell peeling device (10) peels cells (1) fr...
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WO/2023/065019A1 |
A bioreaction system and related methods are disclosed. The system comprises a sonic array comprising two or more transducers, the sonic array being configured to selectively emit sonication, each of the two or more transducers being con...
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WO/2023/055072A1 |
A device for forming a chondroprogenitor cell aggregate according to the present embodiment comprises: a plurality of wells in each of which a micromass is disposed; an electrical stimulation unit which provides electrical stimulation to...
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WO/2023/046709A1 |
The present invention relates to inactivated stem cells, which can be stored for several days in a refrigerator (above 0°C, preferably in the range 0.1-10°C) and still maintain their cellular and phenotypic integrity as well as therape...
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WO/2023/043260A1 |
The present invention relates to a single embryo culture system using sound wave control. The single embryo culture system using sound wave control, according to the present invention, comprises: a substrate which is plated with a conduc...
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WO/2023/039607A1 |
A circuit implementation for on-chip real-time resonance frequency measurement and feedback control may be used to provide improved selective particle trapping. The circuit may be based on monitoring current drawn from the amplifier used...
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WO/2023/039400A1 |
This invention relates to nanodroplet and microbubble particles comprising targeting ligands that bind to a cell of interest. The invention further relates to methods of using the targeted particles for lysis and extraction of cells of i...
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WO/2023/035768A1 |
Provided are a method for differential assembly of heterogeneous cell-containing assembly units by using a Faraday wave, a system, and an application. The method comprises: adding heterogeneous cell-containing assembly units to a dispers...
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WO/2023/035339A1 |
A method and device for electrochemically domesticating anaerobic ammonia oxidizing bacteria, relating to the technical field of water treatment. The device comprises a reactor body, a water inlet system connected to the reactor body by ...
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WO/2023/018244A1 |
The present invention relates to a pharmaceutical composition, prepared by applying an electric stimulus, for treatment of a cartilage-related disease and a preparation method therefor. Specifically, the composition of the present invent...
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WO/2023/018398A1 |
The invention is related to an artificial neural network allowing cell groups to separate if their masses are close to each other or the same in addition to detecting target cells and used by training on the basis of learning based on ce...
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WO/2023/017874A1 |
The present invention relates to a method for production of ammonia, using an inorganic nanoparticle-microbial complex in which a nitrogen fixation reaction in a microorganism is improved by increasing the amount of inorganic nanoparticl...
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WO/2023/015805A1 |
A Bacillus velezensis bred by ultrasound-assisted adaptive evolution, and an application thereof. The Bacillus velezensis comprises a Bacillus velezensis stain US-ALE-BV3 with a preservation number of CGMCC No. 22846 and a Bacillus velez...
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WO/2023/006827A1 |
The invention relates to a method of making a product for human consumption which comprises partially lysed microalgae, said method comprising a) preparing a suspension of microalgae, wherein the microalgae belong to a phylaselected from...
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WO/2023/005676A1 |
Provided are a biological assembly method for Faraday wave multi-wavelength synthesis and an application. The present method has the advantages that a system is easy to build, manipulation is simple, patterns are dynamically adjustable, ...
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WO/2023/001156A1 |
Provided are compositions and methods for effective delivery of polynucleotides into the nuclei of cells through electroporation. A new buffer system is provided that facilitates the delivery with greatly reduced cell toxicity. The buffe...
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WO/2023/003430A1 |
The present invention relates to a method for increasing the thickness of an acellular dermal layer graft. Being capable of increasing the thickness of homologous dermis to a level similar to the skin thickness of a region to be grafted ...
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