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WO/2024/096408A1 |
The present invention pertains to a lipid having amide and ester functional groups, and a method for producing same. More specifically, the present invention pertains to: an ionized lipid that forms a polyplex with an anionic drug and is...
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WO/2024/093625A1 |
The present invention relates to the technical field of biomedicine. Disclosed is a linolenic acid-derived ceramide, which has a structure of general formula I or an isomer of general formula I: (I), wherein R1 is selected from (II) or (...
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WO/2024/087156A1 |
A method for synthesizing 4-hydroxy-N,N,2-trimethylbenzimidazole-6-carboxamide. The process comprises: a method of the present invention for synthesizing 4-hydroxy-N,N,2-trimethylbenzimidazole-6-carboxamide. The method has the characteri...
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WO/2024/089666A1 |
An efficient, economical and continuous process for the preparation of L-lysine-D- amphetamine dimesylate.
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WO/2024/090435A1 |
The present invention pertains to a phenolic compound represented by formula (I) [In formula (I), R1 and R4 each independently represent a hydrogen atom, a hydroxyl group, a C1-3 alkyl group, a C1-8 alkoxy group, a C5-8 cycloalkoxy group...
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WO/2024/090485A1 |
The present invention provides a method for producing a fluorine-containing compound under relatively mild conditions by introducing a fluorine atom into a wide variety of oxygen-containing compounds having a ketone group, an aldehyde gr...
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WO/2024/082523A1 |
The present invention relates to a discoid liquid crystal molecule functional modifier, and a preparation method therefor and the use thereof. In the invention, a discoid liquid crystal molecule functional modifier is first synthesized b...
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WO/2024/086259A1 |
Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3- dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecti...
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WO/2024/078483A1 |
The present invention belongs to the technical field of biological medicines. Disclosed is a novel ceramide which has a structure represented as formula I. Further disclosed in the present invention are a preparation method for and the u...
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WO/2024/074641A1 |
The present invention relates to a method for preparing of an amide of the formula (I-1) or a diamide of the formula (I-2) where the variables areas defined in the claims and the description, by reacting an ester with an aromatic or hete...
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WO/2024/069507A1 |
This invention relates to novel processes for synthesizing N-(3-(6-Amino-5-(2-(N- methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphe
nyl)-4-cyclopropyl-2-fluorobenzamide and to intermediates which are used in such processes.
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WO/2024/067610A1 |
The present application provides a method for preparing L-glufosinate. The method mainly comprises the following steps: addition and rearrangement and ring-opening reactions on a ring lactone with a substituted phosphate-type phosphine r...
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WO/2024/071372A1 |
The present disclosure provides an oxidative cleavage method of a Trolox amide. More particularly, the disclosure provides a method for producing a compound of formula I, the method including a step for contacting a compound of formula I...
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WO/2024/050715A1 |
Provided in the present application are amide compounds having amino groups on both ends, having general formula (I), in which A and B are independently selected from substituted or unsubstituted C1-C18 alkylene groups, C2-C18 alkenylene...
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WO/2024/046175A1 |
Disclosed is a bis((N-3-aminopropyl)-(N-(3,4-dimethoxyphenylpropionyl)))ami
nopropylamine phosphate, a crystal form thereof, and a preparation method therefor. Compared to a free base and other salts of bis((N-3-aminopropyl)-(N-(3,4-dime...
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WO/2024/048438A1 |
The present invention addresses the problem of providing: a diastereomer preparation method whereby it becomes possible to produce a desired diastereomer from a diastereomer mixture with high efficiency; and a solid-phase photosensitizer...
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WO/2024/041460A1 |
The present invention provides compounds of Formula (I) : wherein all of the variables are as defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for the...
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WO/2024/040745A1 |
The present application provides an amide compound containing iodo aryl or iodo heteroaryl, and a preparation method therefor and a use thereof. The amide compound containing iodo aryl or iodo heteroaryl can be used for preparing an X-ra...
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WO/2024/039293A1 |
The present disclosure relates to a method of synthesising hexamethylenediamine and adipic acid. The method comprises homocoupling of acrylamide under conditions including using oxalic acid as a reductant and irradiating a reaction mixtu...
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WO/2024/032081A1 |
The present invention provides a preparation method for semaglutide, and an intermediate. The preparation method comprises the steps of: (1) reacting compound SEM110 and compound SEM120 in a solvent under an alkaline condition to obtain ...
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WO/2024/034746A1 |
The present invention relates to a method for producing a chiral carbonyl derivative using an (R,R)-1,2-diphenylethylenediamine (DPEN)-based thiourea catalyst compound. According to the production method, a chiral carbonyl derivative hav...
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WO/2024/031970A1 |
The present invention relates to a compound having a chemical formula (I), and further relates to a preparation method therefor and use thereof. Pharmacological experiment results show that the compound of the present invention has excel...
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WO/2024/028999A1 |
The present invention addresses the problem of providing a method for efficiently producing an N-[4-methylaminobenzoyl]-L-glutamic acid diethyl ester, which is a pharmaceutical intermediate. In this method for producing an N-[4-methylami...
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WO/2024/018762A1 |
The present invention addresses the problem of providing, without using relatively expensive starting materials, a more conveniently synthesizable pH-sensitive cationic lipid, and providing a lipid nanoparticle that contains this pH-sens...
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WO/2024/011415A1 |
Disclosed in the present invention is a method for preparing an o-iodophenyl compound, wherein an iodobenzene compound and an amide compound as raw materials are reacted in the presence of sodium hydride or n-butyllithium and a solvent t...
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WO/2024/013769A1 |
The present invention relates to a novel process for the solvent free continuous synthesis of amides and peptides. More particularly, the invention relates to a process for synthesizing amides and peptides using coupling reagents where t...
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WO/2024/007851A1 |
A catalyst for amide synthesis and preparation and use thereof are disclosed. The catalyst is a thio or seleno pyranodipyrimidine compound and has a simple and novel structure, high catalytic efficiency, and good atom economy. The cataly...
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WO/2024/003797A1 |
The present invention relates to pure salts of amphetamine prodrug, in particular, L-lysine-d- amphetamine (known as lisdexamfetamine) and industrial advantageous process for preparation thereof. The present invention relates to the crys...
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WO/2024/003671A1 |
A formulation for decreasing aldehyde content in a polymeric material includes a compound which includes at least three moieties of formula (A) wherein each moiety (A) includes an amine moiety (-NH2) bonded ortho or meta to the amide moi...
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WO/2023/249414A1 |
The present invention relates to a method for producing a benzoamine derivative, and more specifically, to a method for producing a benzoamine derivative at high yield and purity using 1,1'-carbonyldiimidazole as a coupling catalyst in o...
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WO/2023/240790A1 |
Disclosed in the present invention is a method for preparing an N-formyl amide compound under the catalysis of visible light. In the method, an LED lamp is used as a light source to provide energy, economical and easily available seconda...
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WO/2023/240791A1 |
Disclosed in the present invention is an environment-friendly preparation method for an N-methylamide compound. An LED lamp is used as a light source to provide energy, an economical and easily available tertiary amide is used as a react...
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WO/2023/237702A1 |
The present invention pertains to a continuous or semi-continuous process for producing a pre-activated organogelator paste, wherein the process comprises : (1) mixing at least one amide compound with at least one liquid carrier so as to...
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WO/2023/234425A1 |
The present invention provides a novel active ester of an amino acid to be used for amino acylation of tRNA, said ester being capable of reducing risks to safety and waste. The present invention provides a compound represented by formula...
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WO/2023/226263A1 |
The present invention relates to the technical field of organic synthesis, in particular to an anilinoacetate and a synthesis method therefor. The synthesis method for an anilinoacetate comprises: S1, adding an anilinoacetate solution an...
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WO/2023/221851A1 |
Provided is a method for preparing valproamide represented by chemical structural formula I and sodium valproate represented by formula II. The method is characterized in that cyanoacetate and 1-chloropropane are subjected to composite c...
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WO/2023/223885A1 |
The present invention provides a production method for an amide group-containing monomer. With the present invention, an amide group-containing monomer in which the amount of impurities is low is efficiently produced, the production meth...
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WO/2023/214694A1 |
The present invention relates to a method for separating and recovering acetic acid and dimethylformamide from waste solvent, the method comprising the steps of: introducing a waste solvent containing water, acetic acid, and dimethylform...
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WO/2023/209165A1 |
The invention relates to a process for the preparation of a 2,4,6-triiodo-phenol derivative of formula (II), which is useful as an intermediate for the synthesis of conventional X-ray contrast agents, said process comprising the tri-iodi...
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WO/2023/208020A1 |
Disclosed are an intermediate of a polyamine derivative pharmaceutical salt, a preparation method therefor, and use thereof. The intermediate compound has the following structure: (I), which can be used to prepare a polyamine derivative ...
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WO/2023/202559A1 |
The application provides a phenyl acrylic compound, and a preparation method and application thereof. The phenyl acrylic compound has a structure as shown in formula (I). The phenyl acrylic compound provided by the present application ca...
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WO/2023/201712A1 |
The present invention provides a clofoctol derivative, which has a structure represented by general formula (1). The clofoctol derivative has high efficiency, low toxicity, wide antibacterial spectrum, fast sterilization speed, excellent...
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WO/2023/198484A1 |
The invention relates to an improved process for recovering N,N-Dimethylformamide (DMF) from an aqueous process stream by adjusting the pH, extracting with Chloroform and subsequent distillation/rectification.
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WO/2023/193341A1 |
Provided are a sphingolipid compound shown in formula (I), a liposome containing the sphingolipid compound, and an application. The sphingolipid compound is prepared by taking a long-chain alkyl group as a hydrophobic tail part, and bond...
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WO/2023/187049A1 |
The present invention relates to a process for separating at least one ε-caprolactam oligomeric compound CPO from a stream SR comprising said at least one CPO and ε-caprolactam monomeric compound CPM.
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WO/2023/190187A1 |
Provided is a maleimide compound having a partial structure represented by -CH(CF3)-. Also provided is a maleamic acid compound having a partial structure represented by -CH(CF3)-. Also provided is a curable compound comprising the malei...
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WO/2023/170715A1 |
The present disclosure provides a compound of Formula (I), its analogs, tautomeric forms, stereoisomers, enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The present disclosure also provides a process for prepari...
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WO/2023/171617A1 |
[Problem] The present invention addresses the problem of providing a novel method for, under simpler and stabler conditions, labeling a radionuclide such as 211At at a high radiochemical yield. [Solution] Provided is a method for produci...
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WO/2023/166346A1 |
Described herein are methods of making crystalline Form 1 of 2-(4-methoxy-3-(3- methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxyl
ic acid.
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WO/2023/156605A1 |
The present invention relates to a novel and efficient method for the production of sphingolipids via the N-acylation of lysosphingolipids such as D-eritro-sphingosine or 6-hydroxy D-eritro-sphingosine, analogues thereof, or salts thereo...
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