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WO/2023/004687A1 |
Provided by the present invention is an unnatural amino acid, which is a compound having a structure as shown in formula (I) or an enantiomer thereof. Further provided by the present invention is an application of the unnatural amino aci...
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WO/2023/001267A1 |
A preparation method for an N-long-chain acyl amino acid dipeptide, supramolecular amino acid and corresponding salts thereof, capable of controlling the occurrence of structural reconstruction and controlling the content of long-chain f...
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WO/2023/285581A1 |
The present invention relates to a method of making sodium N-(8-2-Hydroxybenzoyl)amino caprylate form A, SNAC polymorphic form A having improved stability and the use of said SNAC polymorphic form A in a solid pharmaceutical dosage form-
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WO/2023/283831A1 |
Disclosed in the present invention is a compound having an inhibitory effect on a virus main protease (3CL protease, Mpro), which also has a significant inhibitory activity on the Mpros of SARS coronavirus (SARS-CoV) and novel coronaviru...
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WO/2023/281088A2 |
The present invention relates to a biological method for obtaining an MO monomer comprising an ethylenic unsaturation by bioconversion of a CN compound comprising at least one nitrile function, said CN compound being at least partially r...
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WO/2023/281081A1 |
The present invention relates to a method for obtaining substituted alkyl(meth)acrylamide comprising the reaction between (meth)acrylic acid or one of the esters thereof on the one hand, and a primary or a secondary alkylamine on the oth...
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WO/2023/281086A1 |
The present invention relates to a method for obtaining N-vinylformamide comprising the reaction between an acetaldehyde and a formamide, one of the two, preferably both, being at least partially renewable and non-fossil. The invention f...
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WO/2023/277587A1 |
The present specification relates to a method for preparing an N-acyl derivative by distilling a first composition comprising a compound of chemical formula 1, and using the distilled first composition, an N-acyl derivative prepared ther...
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WO/2023/275091A1 |
An improved preparation of non-steroidal antiandrogen drugs, such as 4-[3-[4-cyano-3- (trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imida
zolidinyl]-2-fluoro-N-methyl- benzamide and intermediates thereof, is described.
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WO/2023/277590A1 |
The present specification relates to: a method for preparing alkyl-D-alaninate, the method comprising a step for distilling a composition, which includes a compound of chemical formula 3 synthesized by reacting chemical formula 1 and che...
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WO/2023/272497A1 |
The present application provides N,N-dihydrocarbonyl amino carboxylic acid, a preparation method therefor, and the use thereof. The N,N-dihydrocarbonyl amino carboxylic acid can act as an extracting agent for enriching rare-earth element...
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WO/2022/266919A1 |
Provided are an N,N-dihydrocarbyl amide carboxylic acid, a preparation method therefor and a use thereof. The N,N-dihydrocarbyl amide carboxylic acid can be used as an extractant to enrich rare earth elements from a low-concentration rar...
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WO/2022/264166A1 |
The present invention relates to process for the preparation of pure Salcaprozate sodium free of color impurities.
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WO/2022/265115A1 |
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino a...
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WO/2022/261634A1 |
Surfactant compositions and derivatives with low amounts of impurities are disclosed along with a method of making the same. A surfactant composition includes greater than 80% by weight of N-acyl amino acid surfactant of formula (I) and ...
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WO/2022/261167A1 |
A method for producing a diglycolamide molecule having the formula: (I) wherein R1 and R2 are independently selected from alkyl groups (R) and acyl groups (C(O)R) in which the alkyl groups (R) contain 1-30 carbon atoms and optionally con...
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WO/2022/261635A1 |
A surfactant composition includes a homogeneous mixture of greater than 70%, by weight, of N-acyl alaninate surfactant of formula (I) and an N-acyl amino acid surfactant of formula (II). A process for preparation of a blend of an N-acyl ...
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WO/2022/249994A1 |
This method for producing N-(hetero)aryl(meth)acrylamide compounds comprises obtaining a compound given by general formula (3) by carrying out an amidation reaction, at a temperature above 120°C, between a compound given by general form...
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WO/2022/248865A1 |
A method for synthesizing 9-aminomethyl tetracycline compounds is disclosed. The method comprises a) reacting minocycline and an hydroxymethylamide derivative to form a 2,9-(methylamide-substituted) minocycline and a 2-(methylamide-subst...
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WO/2022/237485A1 |
The present invention mainly relates to the field of organic synthesis, and disclosed is a continuous synthesis process of 2-acetamido-5-nitroanisole. In the process, a microchannel continuous flow reactor is used as a main reaction devi...
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WO/2022/235530A1 |
A composition for use in psychotherapeutic or medical treatment of an R(-) enantiomer of MDMA or MDA. A method of treating an individual for a medical condition (especially autism and social anxiety disorders), by administering an effect...
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WO/2022/233309A1 |
Disclosed in the present invention are a 150-cavity-targeted Oseltamivir derivative, a preparation method therefor, and an application thereof. The derivative has a structure represented by general formula I or II. Also disclosed in the ...
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WO/2022/232366A1 |
Described herein are novel reduction reactions. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticide...
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WO/2022/229314A1 |
The present invention relates to A process for enzymatic synthesis of amides of formula (III) from amines of formula (I) and compounds of formula (II), characterized in that the lipase is immobilized on a rotary bed reactor or on a spin-...
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WO/2022/221689A1 |
Provided herein are nitrophenyl-acrylamide compounds, their preparation, and uses thereof.
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WO/2022/221629A1 |
Processes that use novel reagents for the removal of colored impurity during the preparation of Salcaprozic Acid and pharmaceutically acceptable salts thereof. The processes include hydrolysis of 8-(2,4-dioxo-1,3-benzoxazin-3-yl)octanoic...
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WO/2022/202888A1 |
The purpose of the present disclosure is to provide a method for producing organic fluorine compounds that enables the thorough removal of sulfur-containing substances, or to provide an organic fluorine compound-containing composition th...
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WO/2022/200247A1 |
The present invention is related to the synthesis of 4-hydroxymethyl-2-oxazolidinone (serinol carbamate, SC), which can be subsequently hydrolyzed to 2-amino-1,3-propanediol (serinol), by reacting glycerol and urea: (I) In general, glyce...
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WO/2022/195288A1 |
The invention relates to a process for preparing an N-acylethanolamide derivative.
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WO/2022/196860A1 |
The present invention relates to a method for manufacturing a temperature- and stress-sensitive film, and a temperature and stress measurement system and, more specifically, to: manufacturing a flexible temperature- and stress-sensitive ...
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WO/2022/188501A1 |
The present disclosure relates to the technical field of resource reutilization, and provides a recycling method for degraded waste of an acetyl Meldrum's acid derivative. According to the present disclosure, the degraded waste of the ac...
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WO/2022/188302A1 |
Disclosed are a pregabalin artificial hapten and a pregabalin artificial antigen, preparation methods therefor, and applications thereof. The molecular structural formula of the pregabalin artificial hapten is as shown in formula (I), an...
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WO/2022/183762A1 |
Disclosed are an anti-phenacetin monoclonal antibody hybridoma cell strain AD, and a preparation method therefor and the use thereof, which relate to the technical field of food safety and immunological detection. The deposit name of the...
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WO/2022/177192A1 |
Disclosed herein are disclosed a novel ceramide and, specifically, 1-O-acylceramide having a structure in which a phytosphingosine base has fatty acid chains attached thereto in opposite directions, an isomer thereof, a salt thereof, a s...
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WO/2022/170834A1 |
Disclosed in the present invention is the use of an ionizable cationic lipid analog material as a protein drug delivery carrier. The cationic lipid analog material of the present invention has an efficient capability of intracellular del...
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WO/2022/162132A1 |
The present invention relates to a chemical process for the synthesis of the compound 8-[(2-hydroxybenzoyl)amino]octanoic acid or a derivative thereof useful in the process of making sodium 8-[(2-hydroxybenzoyl)amino]octanoate (SNAC), a ...
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WO/2022/155946A1 |
A copolymer additive comprising water and a copolymer prepared from an acetoacetamide functional monomer and a ureido monomer is stable in a wide range of pH values and a coating composition comprising such copolymer additive can provide...
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WO/2022/157106A1 |
The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.
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WO/2022/157633A1 |
The invention relates to enantiomerically pure desglymidodrine and process for preparation thereof. In particular, the invention relates to enantiomerically pure desglymidodrine or a pharmaceutically acceptable salt, solvate or a hydrate...
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WO/2022/145923A1 |
The present invention relates to a pharmaceutical composition which is for preventing or treating viral infections and contains a piperlongumine-based compound as an active ingredient. Specifically, the piperlongumine-based compound acco...
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WO/2022/145707A1 |
The present invention provides a novel piperlongumine-based compound, and an immunomodulator and a health functional food for immunomodulation, which comprise the compound or a pharmaceutically acceptable salt or solvate thereof as an ac...
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WO/2022/134287A1 |
The present invention relates to a method for preparing a carboxylic acid ester compound. Under the catalysis of nitrite, an carboxylic acid reacts with an alcohol in air so as to obtain an ester compound; and the alcohol is ethanol, pro...
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WO/2022/135617A1 |
Provided in the present invention are a novel NAMPT enzyme agonist and a preparation and a use thereof. The structural formula of the agonist is as shown in formula I or formula II. In the present invention, an NAMPT agonist NAT is scree...
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WO/2022/140654A1 |
The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts thereof.
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WO/2022/134204A1 |
Disclosed are a novel method for preparing glycollic amide and the preparation of a catalyst therefor. The present invention belongs to the technical field of coal chemical engineering and catalysts. The present invention involves prepar...
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WO/2022/139594A1 |
Method for the preparation of two amides from one amidine in a one-pot conversion, where amides of formula (I) or formula (II) are formed. Formula (Ia) and Formula (Ib) Fornula (IIa) and Formula (IIb).Obtained amides and their useful app...
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WO/2022/134297A1 |
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...
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WO/2022/134203A1 |
Disclosed is a novel method for preparing monoethanolamine, and the present invention belongs to the field of coal chemical engineering. The method of the present invention involves using methyl glycolate, which is an intermediate produc...
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WO/2022/117415A1 |
The invention relates to a process for preparing surfactant solutions with N-acyl amino acids or their salts and to surfactant solutions with N-acyl amino acids or their salts obtained by the inventive process. The invention relates furt...
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WO/2022/106254A1 |
The present invention relates to a process for producing L-phenylalanine amide.
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