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JPH03163078A |
NEW MATERIAL:A compound shown by formula I [R1 is H or 1-4C alkyl; Xb and Yb are H or OH; Z is amino, mono- or di-(1-4C alkyl)amino, etc.]. EXAMPLE: (3aR,4R,12aR,12bS)4-amino-2,3,3a,4,5-12,12a,12b-octahydro-6-
hydroxyindolo[3,2,1-ij]ben...
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JPH03119996A |
PURPOSE: To separate and recover a nonesterified S-enatiomer by reacting a specific racemic mixture with an alcoholic compound in the presence of an enzyme. CONSTITUTION: An alcohol (VIII) such as methanol and a racemic starting substanc...
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JPH0324033A |
NEW MATERIAL: A compd. represented by formula I or II [R1 is (substd.) alkyl, alkoxy, alkenyl, (substd.) cycloalkyl, (substd.) phenyl, amino, mono-or dialkylamino, piperdinyl, pyrrolidinyl or R3S (R3 is alkyl or substitutable phenyl); an...
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JPH02312593A |
PURPOSE: To synthesize in large quantity and put to practical use of a product having highly optical purity while suppressing an occurrence of carbon dioxide gas and a production of by-product by carrying the subject reaction under aerob...
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JPH0219836B2 |
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JPH0214036B2 |
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JPH0253498A |
PURPOSE: To provide a method for resolving a specific substrate in a high purity and at a low cost by reacting the same with an alcohol such as ethyl alcohol in the presence of a lipase originated from a microorganism. CONSTITUTION: This...
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JPH021463A |
NEW MATERIAL:A compound expressed by the formula [X and Y are single bond or -C(=O)-]. USE: Useful as medicines, such as bronchodilator, cardiotonic agent, vasodilator, hormone secretion promoter or antiallergic agent. PREPARATION: A mic...
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JPH01250341A |
NEW MATERIAL:Physiologically active substances expressed by the formula [R is -SCH2CH2C(=O)CH3 (KS-506m) or -OCH3 (KS-506h)]. USE: Physiologically active substances having inhibitory action on liberation of histamine produced by microorg...
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JPH01228485A |
PURPOSE: To obtain the subject derivative in high efficiency at a low cost by reacting a diol of a glycerol derivative with a 1W30C fatty acid in the presence of a specific enzyme taking advantage of the stereo-selectivity of the enzyme....
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JPH01502117A |
Therapeutical compositions containing products obtained from the addition of thiols to prostaglandines or analogues of prostaglandines. These compositions have an antitumoral activity.
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JPH0127717B2 |
The enzyme D-2-hydroxy-4-methylpentanoic acid dehydrogenase has been prepared by culturing readily available Lactobacillus or Leuconostoc, microorganisms, such as Lactobacillus casei ssp. pseudoplantarum and Leuconostoc mesenteroides. Th...
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JPH0124128B2 |
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JPH0195795A |
PURPOSE: To efficiently produce 2-thiopheneacetic acid under condition of ordinary temperature under ordinary pressure, by converting 2-thiopheneacetonitrile by action of a microorganism having nitrilase activity. CONSTITUTION: 2-Thiophe...
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JPH0191789A |
PURPOSE: To efficiently produce an optically active β-substituted glutaric acid monoester, by alcoholizing a β-substituted glutaric acid anhydride in the presence of an aliphatic alcohol in an organic solvent containing an enzyme suspe...
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JPS642590A |
PURPOSE: To efficiently convert a sulfide having an oxygen functional group at the β-position into a sulfoxide and sulfone corresponding to the above- mentioned sulfide, by aerobically cultivating a specific bacterium belonging to the g...
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JPS63245694A |
PURPOSE: To readily obtain the titled carboxylic acid and antipodal ester thereof useful for synthesizing various physiologically active substances, etc., in good yield, by reacting a specific ester with a microorganism capable of asymme...
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JPS63245695A |
PURPOSE: To readily obtain the titled carboxylic acid useful for synthesizing various physiologically active substances, etc., in good yield, by reacting a specific carboxylic acid with a microorganism having the ability to asymmetricall...
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JPS63240793A |
Method for preparing thiol compounds by coupling cysteine having the formula HS-CH2-CH(NH2)COOH via an -S- bridge to a hydrocarbon compound and subsequently reacting the cysteine conjugate obtained with beta -lyase to form the relevant t...
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JPS63207390A |
PURPOSE: To obtain an optically active halogen-containing carbonyl compound in high yield and purity in a short time, by carrying out addition reaction of two kinds of substrates having specific structural formulas in an organic phase in...
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JPS63137696A |
PURPOSE: To obtain the titled compound, having excellent antimicrobial action and inhibitory activity against β-lactamases and useful as medicines and veterinary drugs, by cultivating a specific microorganism belonging to the genus Stre...
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JPS6339838A |
By differentiating the two enantiotopic groups in prochiral glycerol dervatives, chiral molecules are obtained directly and in turn can be easily converted by selective manipulation of the functional groups not only into the but also int...
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JPS633599B2 |
PURPOSE:To prepare a beta-substituted propionic acid (amide) from a beta-substituted propionitrile in high selectivity under mild conditions, by utilizing a specific microorganism. CONSTITUTION:A bacterium of actinomyces belonging to the...
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JPS62289193A |
PURPOSE: To stably produce a large amount of a sulfur-containing compound such as alliin at a low cost, by culturing callus originated from a tissue of garlic. CONSTITUTION: A piece of garlic bulb is sterilized and a tissue piece is coll...
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JPS62212352A |
PURPOSE: The reaction of S-chloromethyloxirane with trimethylamine gives S-3-chlor-3-hydroxypropyltrimethylammonium chloride which is used as a syn thetic intermediate of carnitine in high yield. CONSTITUTION: S-Chloromethyloxirane of fo...
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JPS62209049A |
PURPOSE: To extract and separate the titled compound, by adding an aqueous solution of trimethylamine hydrochloride to a mixture containing an optically active ester and halogenomethyloxirane under specific condition, selectively convert...
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JPS61265098A |
PURPOSE: To convert many dithioacetals into their oxides rapidly in high yield, by cultivating a bacterium belonging to the genus Corynebacterium, capable of oxidizing a dithioacetal in a medium containing the dithioacetal. CONSTITUTION:...
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JPS6120274B2 |
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JPS6111591B2 |
The purpose of the invention is the new enzyme L-2-hydroxy-4-methylpentanoic acid-dehydrogenase and its recovery from Lactobacillus confuses. The new enzyme can be used to enzymatically change L-2-hydroxy-4-methylpentanoic acid and vario...
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JPS6054303B2 |
There are disclosed polyprenyl sulfone derivatives of the general formula: (I) wherein n represents an integer of 1-4, R1 represents an aryl group and R2 represents a hydroxymethyl or carboxyl group. The polyprenyl sulfone derivatives ar...
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JPS608119B2 |
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JPS58188851A |
NEW MATERIAL:A compound shown by the formula (X and Y are OH or acetoxy) and its salt. EXAMPLE: PF1057A. USE: The titled substance has β-lactamase inhibiting activity, and the use of the substance and a β-lactam-based antibiotic (e.g.,...
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JPS55131396A |
PURPOSE: To obtain dimethyl sulfoxide and dimethyl sulfone, by bringing one or more of methyl mercaptan, dimethyl sulfide, etc into contact with a mold with oxidation power under aeroboic states without limiting particularly the conditio...
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JPS5528679B1 |
1277150 Antifungal and antibacterial preparations UPJOHN CO 27 Aug 1970 [9 Oct 1969] 41358/70 Headings A5B and ASE [Also in Division C2] Therapeutically active compounds which have antibiotic (see Division C2), antifungal and antibacteri...
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JPS5512237B1 |
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JPS5422514B2 |
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JPS5212277B2 |
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