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WO/1987/005328A1 |
A process for resolving racemic 3-acylthio-2-methylpropionic acid esters by enantiospecific hydrolysis utilizing extracellular lipases of microbial origin (EC 3.1.1.3). The desired chiral products can be readily converted to captopril.
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WO/1986/001536A1 |
A DNA fragment that codes for the portion of Bacillus thuringiensis crystal protein peptide that is toxic to lepidopteran insects. The invention also comprises the DNA and amino acid sequences for the disclosed toxin-encoding DNA fragmen...
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JP7475007B2 |
To provide a method for culturing microorganisms that increases the amount of production of ergothioneine.A method for producing ergothioneine includes the step of culturing Pseudozyma yeast in a medium, to prepare a culture containing e...
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JP2024038277A |
A selective process for preparing organic sulfoxides from organic sulfides by enzyme catalysis, as well as compositions that enable the performance of this process, and methods of use thereof. A process for preparing sulfoxide is provide...
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JP2024507753A |
Described herein are materials and methods for converting the non-volatile form of 3-sulfanyl-1-hexanol (3SH) to free 3SH during the brewing process. [Selection diagram] Figure 1
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JP7424320B2 |
A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3′-phosphoadenosine-5′-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobac...
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JP2024503380A |
The present invention relates to methods for preparing linkers that are useful in the conjugation of therapeutic molecules (eg, cytotoxic agents) and targeting moieties (eg, proteins, peptides, antibodies, nanoparticles, nucleic acids). ...
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JP2024501167A |
The present invention provides that the formula R in the presence of at least one enzyme selected from sulfhydrylases2-XC*H(NR1R7)-(CH2)n-G(II) compound and H2Regarding processes for synthesizing functionalized mercaptans, including reac...
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JP2023547024A |
The present invention is based on the formula H2N-CH(R)-CH2-SO2H sulfinic acid, H2O2By an enzyme selected from the class of oxidases produced, in the presence of a substrate of said enzyme, the formula H2N-CH(R)-CH2-SO3The present invent...
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JP2023542204A |
The present invention relates to the fields of protein engineering and biocatalysis, and more particularly to novel polypeptides with peroxygenase activity and related methods and uses thereof. A method of producing melanin or melanin-li...
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JP2023093532A |
To provide a genetically modified bacterium for enhancing production biotin or lipoic acid or thiamine.Provided is a genetically modified bacterial cell capable of improving iron-sulfur cluster transportation characterized by a modified ...
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JP7293351B2 |
Provided are a monooxygenase mutant and use thereof. An amino acid sequence of the monooxygenase mutant is obtained by mutation of an amino acid sequence shown in SEQ ID NO: 1, and the mutation at least includes one of the following muta...
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JP2023517686A |
A chemoenzymatic process for co-generating disulfides and sulfoxides or sulfones. The present invention relates to a chemoenzymatic process for co-producing disulfides and sulfoxides or sulfones from a composition M comprising: (1) a sul...
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JP2023517110A |
The present application relates to a novel glutamate-cysteine ligase mutant and a method for producing glutathione using the same. The present application provides a glutamate-cysteine ligase variant in which the amino acid corresponding...
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JP2023512578A |
The present disclosure relates to cannabinoid sulfate esters, soluble salts thereof and stable formulations thereof and food, beverage and pharmaceutical formulations thereof. Cannabinoid sulfates are associated with pain and inflammatio...
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JP2023012497A |
To provide monooxygenase mutants and use thereof, in order to improve selectivity and enzymatic activity of monooxygenase.An amino acid sequence of a monooxygenase mutant is an amino acid sequence obtained by the mutation of a specific a...
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JP2022553039A |
Provided herein are genetically modified yeast cells that recombinantly express a gene encoding a mutant beta-lyase. Also provided are methods of producing fermentation products and methods of producing ethanol.
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JP2022550052A |
The present invention relates to a method for producing graphene dual-doped with nitrogen and sulfur atoms through microbial reduction of graphene oxide. In addition, the present invention relates to graphene dual-doped with nitrogen and...
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JP2022549547A |
The present invention provides a selective process for the preparation of sulfones from sulfides by enzyme catalysis, and a symmetric sulfide, an oxidoreductase enzyme that catalyzes the oxidation of said symmetric sulfide to a symmetric...
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JP2022549546A |
The present invention provides a selective process for the preparation of sulfoxides from sulfides by enzyme catalysis, and a symmetric sulfide, an oxidoreductase enzyme that catalyzes the oxidation of said symmetric sulfide to a symmetr...
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JP7120007B2 |
Provided are a method for producing flavor ingredients such as diallyl sulfide (ALS) and diallyl disulfide (ALDS), and a technology related to such method. Flavor ingredients such as diallyl sulfide (ALS) and diallyl disulfide (ALDS) are...
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JP2022523225A |
The monooxygenase mutant and its use are disclosed. The amino acid sequence of the monooxygenase mutant is an amino acid sequence obtained by mutating the amino acid sequence shown in SEQ ID NO: 1, and the mutations are at least at posit...
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JP7036713B2 |
Provided is an enzymatic process for the preparation of a mercaptan of formula R—SH from disulfides utilizing hydrogen.
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JP7036714B2 |
Provided is an enzymatic process for preparing mercaptans from disulfides.
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JP7022755B2 |
Provided is process for the synthesis of at least one functionalized organic polysulfide.
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JP6894650B2 |
A method for producing an α-keto acid includes a step of culturing a microorganism containing a gene encoding an enzyme that catalyzes an aldol reaction between pyruvic acid and a carbonyl compound in the presence of a pyruvic acid-supp...
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JP6895953B2 |
Herein is reported a method for the enzymatic production of a thioester comprising incubating i) a first polypeptide comprising the amino acid sequence LPXTG (SEQ ID NO: 01, wherein X can be any amino acid residue), ii) a second polypept...
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JP2021512605A |
The present invention belongs to the technical field of genetic engineering and provides a monooxygenase mutant, a method for producing the same, and an application thereof. The monooxygenase mutant has any of the amino acid sequences sh...
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JP6853549B2 |
To provide a method for improving the enzymatic activity of a modified meso-diaminopimelic acid dehydrogenase derived from a Ureibacillus bacterium having activity against various D-amino acids.A modified meso-diaminopimelic acid dehydro...
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JP2021503287A |
Described herein are the nucleotide sequences of the oxygenase subunit (StyA) and the reductase subunit (StyB) with respect to the isolated nucleic acid fragments encoding the oxygenase subunit (StyA) and the reductase subunit (StyB). Th...
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JP6792783B2 |
A process for production and extraction of dihydrolipoic acid (DHLA) relates to the biotransformation of R-lipoic acid to dihydrolipoic acid. The process ferments the lipoic acid with bacteria selected from the genus of any of the follow...
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JP2020188784A |
To provide a method for producing mercaptans from disulfides by enzyme catalytic action, in particular for producing methylmercaptan from dimethyl disulfide.Provided is a method for preparing a mercaptan of the formula R-SH, which compri...
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JP2020185003A |
To provide methods for producing mercaptans from disulfides and hydrogen by enzymatic catalysis, in particular, methyl mercaptan from dimethyl disulfide and hydrogen.Disclosed is a method for preparing a mercaptan of formula R-SH, compri...
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JP2020527359A |
The present invention features a modified gene encoding a mutant iron-sulfur cluster regulator (IscR) and one or more transgenes encoding a polypeptide that enhances the biosynthesis of either biotin, lipoic acid or thiamine. Provided ar...
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JP6573944B2 |
Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioest...
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JP6573873B2 |
Provided is a method for producing a hydrogel, which enables a hydrogel comprising polyethylene glycol to be produced under low peroxidase concentration conditions and physiological conditions. The method for producing a hydrogel involve...
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JP2019129708A |
To provide a method for producing hypotaurine and/or taurine.Microorganisms having an L-cysteine production ability, modified to have increased cysteine dioxygenase activity and sulfinoalanine decarboxylase activity, are cultured in a cu...
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JP6531304B2 |
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JP6480258B2 |
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JP6469342B2 |
Converting substituted carboxylic acid ester compounds (I) with a cell, comprises (a) contacting the cell with the carboxylic acid ester in an aqueous solution, where the cell is a recombinant cell in which the activity of a polypeptide ...
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JP6429821B2 |
Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioest...
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JP2018527937A |
Describes a method of enzymatically producing acyl phosphate from 2-hydroxyaldehyde using phosphoketolase or sulfoacetaldehyde acetyltransferase.
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JP2017533734A |
This specification describes a biochemical pathway for producing 6-hydroxycaproic acid using a polypeptide having β-ketothiolase activity to form a 3-oxo-6-hydroxyhexanoyl-CoA intermediate. Describe. 6-Hydroxycaproic acid can be enzymat...
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JP6225108B2 |
A method for increasing the concentration of free methionine in at least a part of a tobacco plant, comprising the steps of: (a) reducing the expression or activity of threonine synthase in the tobacco plant, wherein the threonine syntha...
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JP6180933B2 |
Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioest...
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JPWO2016017631A1 |
An object of the present invention is to provide a method for producing glutathione and its precursor, γ-glutamylcysteine, in a high yield. The method for producing glutathione of the present invention has, as means for solving the abov...
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JPWO2016013225A1 |
To provide a technique relating to a novel method for producing a diphenyl sulfide derivative. A method for producing a compound represented by the general formula (5) by asymmetrically hydrolyzing a compound represented by the general f...
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JP5847840B2 |
The present invention is related to a method for the fermentative production of hydroxymethionine, comprising the steps of: culturing a recombinant microorganism modified to produce methionine in an appropriate culture medium comprising ...
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JP5771405B2 |
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JP2015149910A |
To provide a method for specifically and effectively as compared to conventional methods, producing a glutathione-added phenylpropane-based compound which is an intermediate of a phenylpropane-based compound, from a carbonyl phenyl propa...
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