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WO/2024/014426A1 |
The present invention addresses the problem of clarifying the true cause of interstitial pneumonia that is associated with myositis/dermatomyositis to thereby enable a more accurate diagnosis of the onset risk of interstitial pneumonia a...
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WO/2024/014317A1 |
[Problem] To provide a cell culture device that, when culturing adherent cells with a bag-shaped culture container, makes it possible to efficiently separate the adherent cells from the culturing surface and obtain a single cell. [Soluti...
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WO/2024/013301A1 |
An assay plate system (1100) for assaying a cell culture model such as an organoid is described. The assay plate system comprises an assay plate (200) comprising an upper surface (201) and comprising a grid array of wells comprising at l...
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WO/2024/013449A1 |
The invention relates to a facility for cellular tissue culture, comprising a distribution system comprising: a mount suitable for receiving at least two cellular tissue culture dishes, and a first, second and third fluid distribution ne...
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WO/2024/015532A1 |
Embodiments of the present disclosure generally relate to extracts of coal, compositions thereof, and uses thereof. Embodiments of the present disclosure also generally relate to processes for extracting coal. In an embodiment is provide...
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WO/2024/014976A1 |
The group of inventions relates to the fields of biotechnology, plant cultivation, pharmacognosy and biochemistry, and more particularly to a device and method for delivering target components to the intercellular space of plant tissues ...
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WO/2024/013521A1 |
The invention provided herein relates to methods for protein synthesis, purification and characterisation.
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WO/2024/013652A1 |
The present invention relates to the field of microbiological analysis. The present invention relates to a cellulose-based microbiological culture device of bio-based and biodegradable materials, comprising a high-water absorbent cellulo...
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WO/2024/013217A1 |
The present invention relates to an enzymatic synthesis apparatus configured for the synthesis of biomolecules, comprising a support platform (18) having a receiving area configured to receive a substrate plate (16) on which ink drops co...
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WO/2024/011770A1 |
The present application discloses a cell centrifugal culture apparatus. The cell centrifugal culture apparatus comprises: a housing, wherein the housing is internally provided with a cavity, the cavity is used for accommodating a centrif...
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WO/2024/015886A2 |
A microbiological process for conversion of CO2 into one or more bio-products, the process comprising the steps of: i. contacting raw carbon dioxide and sulfur-containing feedstocks in one or more gas contactor or absorption columns with...
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WO/2024/014421A1 |
The present invention addresses the problem of providing a dispensing preparation device capable of stirring a cell suspension without damage to cells. The problem is solved by a dispensing preparation device comprising: a reservoir whic...
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WO/2024/013448A1 |
The invention relates to a cell tissue culture and transport canister comprising: a canister body having an accessible interior and an upper opening; a filter arranged inside the canister body or outside the canister and placing the inte...
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WO/2024/013213A1 |
The present invention relates to a supporting platform (18) configured to receive a substrate plate (16) on which ink drops containing biomolecules are disposed, said platform comprising a main wall (28) on which receiving means (38, 40)...
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WO/2024/012260A1 |
An infusion bottle is used for conveying or storing cell fluid in a sterile environment, and comprises a bottle body (10). The bottle body (10) has a hollow inner chamber; a first channel port (11), a second channel port (12) and a third...
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WO/2024/012886A1 |
The present invention relates to a substance treatment device (D) for treatment of a substance. Said substance treatment device comprises a gas sealable container (10) arranged to house a solid particulate substance (S), a gas inlet arra...
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WO/2024/012073A1 |
Provided are an osteosarcoma organoid model and a construction method therefor. The osteosarcoma organoid model at least comprises a biological scaffold, osteosarcoma cells, and exosomes derived from mesenchymal stem cells, wherein the o...
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WO/2024/015203A1 |
A closure 1; 1' for a bioreactor 200; 200'; 200", said closure being configured for being connectable to a container 100; 100'; 100" such that the closure 1; 1' and the container 100; 100'; 100" together constitutes the bioreactor 200; 2...
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WO/2024/012887A1 |
The present invention relates to a substance treatment device (D) for treatment of a substance. Said substance treatment device comprises a gas sealable container (10) arranged to house a solid particulate substance (S), a gas inlet arra...
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WO/2024/008988A1 |
The invention relates to a cleaning system for bioreactors for the multiplication of yeast, fungi and bacteria, of the type including a cleaning system based on one or more balls, formed by a water heater (A) connected to a pressure pump...
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WO/2024/009678A1 |
Provided is a cell culture system capable of efficiently transferring cells in a bag-shaped culture vessel. This cell culture system, which cultures cells by using a culture vessel (10) having at least two ports (12, 13), comprises: a pr...
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WO/2024/010020A1 |
The present invention addresses the problem of providing: a matured cultured cell sheet which is constructed from cardiac myocytes without using a specific medical agent; and a method for producing the same. The present invention also ad...
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WO/2023/150365A9 |
A device and method for detecting the presence of, or measuring the concentration or amount of, at least one large analyte in a sample fluid. The device has at least one electrode, a sample fluid and a plurality of aptamers capable of bi...
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WO/2024/007622A1 |
The present application provides an integrated micro-droplet chip and a micro-droplet multi-index detection method therefor and belongs to the technical field of digital PCR analyzers. The micro-droplet chip comprises a chip body on whic...
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WO/2024/007530A1 |
The present invention belongs to the technical field of intestinal organ chips and provides an optimization method for preparing an intestinal organ chip for exploring Hg2+. In the present invention, a channel is formed in each of a firs...
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WO/2024/008741A1 |
The present invention provides a process and a bioreactor for reacting hydrogen with carbon dioxide to form methane in an aqueous medium catalysed by microorganisms, where said reaction takes place inside a bioreactor, characterised in t...
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WO/2024/010064A1 |
This cell culture apparatus is equipped with a hydrogel chamber, a culture vessel and a pneumatic device. The hydrogel chamber holds a hydrogel for culturing a cell. The culture vessel is equipped with a first culture solution storage un...
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WO/2024/008866A1 |
The present invention relates to a method for the production of a protein matrix composition having a textured structure from solid-state fermentation of food grade and/or agricultural biomass substrate, wherein the protein matrix compos...
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WO/2024/011114A1 |
A cell culture device includes an interior space defined between a first wall and a second wall, a diaphragm disposed between a first chamber and a second chamber of the interior space, the diaphragm including a first section being liqui...
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WO/2024/007078A1 |
A biomechanical characterization system comprising a perfusion system including a culture chamber, a first and a second endplate disposed opposite one another inside the culture chamber, and a loading system kinematically coupled to the ...
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WO/2024/010278A1 |
The present invention pertains to artificial skin using fibroblasts and keratinocytes, and more specifically to a method for manufacturing artificial skin using cells differentiated from induced pluripotent stem cells. To this end, a met...
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WO/2024/009636A1 |
Provided are a well plate that exhibits exceptional cell adhesion properties and low drug sorption properties, and a culture method.　Specifically provided is a well plate having a bottom surface member and a well side wall member, wher...
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WO/2024/010872A1 |
A method of growing isolated mitochondria includes selecting a source of mitochondria and stem cells, extracting the stem cells and the mitochondria from the source and segregating the stem cells and the mitochondria into first and secon...
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WO/2024/007051A1 |
The present invention relates to a biocompatible implantable scaffold comprising a first scaffold portion comprising a first array of spaced walls having a first height, wherein the walls of the first array of spaced walls are connected ...
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WO/2024/011248A1 |
Compositions and articles comprising scleroglucan that can be used for culturing and enumerating microorganisms even after exposure to sterilizing doses of radiation. The compositions also include one or more water swellable polymers oth...
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WO/2024/008760A1 |
The present invention refers to a bioreactor, comprising: a conveyor belt located inside the bioreactor, the conveyor belt configured to provide one of a continuous or intermittent rotation movement of a solid surface within the bioreact...
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WO/2024/007503A1 |
The present application provides a cell regulation device, comprising a laser light source, an optical channel apparatus, and a culture apparatus. Cells to be regulated are provided in the culture apparatus. In accordance with the scient...
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WO/2024/010279A1 |
The present invention relates to artificial skin using fibroblasts and keratinocytes, and, more specifically, to a device for producing artificial skin using cells differentiated from induced pluripotent stem cells. In this regard, the d...
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WO/2024/009213A1 |
An apparatus and method for in vitro milk production includes a reactor assembly with an elongated shell that encloses one or more hollow semipermeable tube within an extracellular nutritional medium. A monolayer of lactating cells is fo...
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WO/2024/004371A1 |
Provided is a live bacteria quantifying method comprising: a deposition step in which bacteria is placed in a measuring vessel containing a redox substance that is permeable to the cell membranes of the live bacteria to be measured, that...
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WO/2024/006223A1 |
A fermentation device, system and. method for the production of improved fermentation products is disclosed. The device has a chamber, a temperature control element for heat transfer to/from the chamber, a ventilation fan, an air pump fo...
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WO/2024/006234A1 |
An apparatus includes a sequencing stage and an illumination assembly. The sequencing stage is configured to receive a flow cell that includes a. plurality of reaction sites. Each reaction site is configured to contain a biological sampl...
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WO/2024/004839A1 |
The present invention provides a membrane separation device suitable for inhibiting the hygienic state inside the membrane separation device from deteriorating. The membrane separation device is equipped with a spiral membrane element. T...
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WO/2024/004580A1 |
[Problem] To provide: a novel pathological marker useful in testing disease progression toward vasculitis and in testing the risk of COVID-19 becoming severe; and a means, using the marker, of testing disease progression toward vasculiti...
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WO/2024/006236A1 |
Disclosed herein are flexible facilities for manufacturing at least one therapeutic product, where the flexible facilities include a reconfigurable, single-use area and a stainless steel area that may be optionally segregated by a partit...
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WO/2024/004917A1 |
A nucleic acid that has been amplified in a reaction solution is detected easily and at good sensitivity. The detection system comprises a reaction unit, having an amplification unit that subjects the nucleic acid to an amplification rea...
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WO/2024/005059A1 |
This target molecule reduction method includes: a first step for reducing disulfide bonds in target molecules present in a reaction system with a thioredoxin whose state changes between oxidized and reduced forms and that is in the reduc...
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WO/2024/000622A1 |
An enzyme electrochemical measurement device for determining the concentration of an analyte in a fluid by using a short-life enzyme. The device is formed by generating a film on a substrate (1), the film being immersed in a fluid under ...
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WO/2024/006893A1 |
Embodiments described herein generally relate to assemblies, systems, and methods for cell culture and production of biologics. Disclosed herein are multi-purpose assemblies that facilitate combination of perfusion processes and harvest ...
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WO/2024/002330A1 |
A method for preparing an antibody-drug conjugate. The antibody-drug conjugate is formed by means of site-directed conjugation on the basis of an N-glycosylation site of an Fc region of an antibody. The method comprises: (1) providing a ...
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