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WO/2024/034888A1 |
The present invention relates to a microfluidic device capable of confirming sustained anticancer activity of a drug and the enhanced permeability and retention (EPR) effect of a nanoparticle formulation of the drug, and a method for con...
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WO/2024/031174A1 |
A process to increase the amount of methane produced from a bio-digester, said method comprising the steps of: - providing a digester adapted to receive a feed and capture a biogas composition resulting from biodigestion; - adding to sai...
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WO/2024/035931A1 |
An assay test kit for testing an insect for an infectious disease comprises an insect macerator and a lateral flow assay test strip. The kit may further comprise a liquid carrier, a filter, an assay sample dispenser, and an insect captur...
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WO/2024/033450A1 |
The present invention relates to methods and kits for the collection, preservation and storage of analytes of interest present in biological test samples (biofluid samples). In particular, the present invention relates to means to collec...
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WO/2024/031805A1 |
The present invention relates to the field of bioengineering, and specifically, to an integrated extraction kit. The integrated extraction kit comprises a kit body, an extraction part, and an amplification part. The extraction part compr...
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WO/2024/032884A1 |
A method of operating a fermentation device (1) having an elongated vessel (3) and multiple stirrer devices (11, 12, 13, 14, 15, 16) comprises the following steps: - introducing substrate containing organic material via the at least one ...
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WO/2024/033994A1 |
Provided is a temperature control device comprising a housing, a partition plate that partitions the housing into an upper portion and a lower portion, a temperature control unit, and an exhaust fan, wherein the temperature control unit ...
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WO/2024/015605A9 |
The present disclosure relates to systems and methods for immune therapy. For example, a method can be used to enhance the proliferation of chimeric antigen receptor (CAR) T cells in a subject, The method comprises administering to the s...
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WO/2024/036066A1 |
A tray insert for use with an apparatus configured to analyze a sample is disclosed. The tray insert includes a first surface comprising an elongated channel adapted to receive a reagent strip for sample analysis. Further, the insert inc...
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WO/2024/032582A1 |
Methods, devices, and systems for managing peripheral blood cells are provided. In one aspect, a fully automatic peripheral blood separation method includes: adding a peripheral blood sample liquid in a sample bag and a gradient liquid i...
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WO/2024/030477A1 |
A cell culture matrix for culturing cells in a fixed bed reactor is provided. The cell culture matrix includes a first substrate material with an ordered and regular array of openings passing through the layer, the openings being separat...
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WO/2024/027121A1 |
The present invention relates to the technical field of nucleic acid sequencing. Disclosed are a biochemical reaction apparatus and a nucleic acid sequencing device. The biochemical reaction apparatus comprises a reaction container, a li...
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WO/2024/027119A1 |
Provided are a nucleic acid sequencing system and a sequencing control method. The nucleic acid sequencing system comprises a biochemical reaction apparatus (10), a sample loading apparatus (20), a detection apparatus (30), and a transfe...
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WO/2024/030965A2 |
Described herein are reinforced gas-permeable cell culture apparatus that allows for gas exchange without disturbing the cell culture, including cell cultures in a fully closed culture system. Also described are kits/systems comprising s...
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WO/2024/028064A1 |
The invention concerns a sterile enclosure (2) and a method of printing and culturing a three-dimensional biological structure in the sterile enclosure. The sterile enclosure comprising: - a base wall (10), - a flexible side wall (8); th...
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WO/2024/027717A1 |
The present disclosure relates to the technical field of in-vitro organs, and in particular to a total system and a method for full automatic preparation, sorting, and distribution and culturing of in-vitro organ microspheres.
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WO/2024/028066A1 |
The invention concerns a sterile enclosure (91) comprising a container (92) and a printing needle holder device (58) fixed to the container. The container comprising a base wall (92), a side wall (94), the side wall and the base wall del...
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WO/2024/028314A1 |
The invention relates to an incubator for living cell cultures, to a method for using an incubator, and to a system comprising an incubator. An image capturing system is used to determine whether the incubator is occupied using a mathema...
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WO/2024/028886A1 |
The present invention discloses a miniature quantitative polymerase chain reaction (qPCR) apparatus. A qPCR works on the principle of amplification of nucleic acids from a small sample. The efficiency and uniformity of the nucleic acid a...
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WO/2024/029125A1 |
Disclosed are a method, device, and information processing program for determining a necrosis cell region in an object to be observed, using refractive-index distribution data pertaining to the object to be observed.
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WO/2024/029561A1 |
Provided is a tumor-bearing immune nonhuman animal that enables suppression of the onset of graft-versus-host disease (GVHD) and engraftment of T cells and/or B cells. Human peripheral blood monocytes are transplanted into a tumor-bear...
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WO/2024/030517A1 |
An incubation system for gas detection of a biological specimen includes an optical gas sensor. The sensor (210) is arranged to be placed in communication with a biological specimen vessel (215) for generating a response signal. The spec...
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WO/2024/029124A1 |
Disclosed are a method, a device, and an information processing program for determining, by using refractive index distribution data pertaining to an object to be observed, the region of a cell that has undergone programmed cell death in...
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WO/2024/028712A1 |
The invention concerns a well insert (1) for a multi-well plate (2) and a multi-well plate system for use in cell culture. The well insert comprises a planar support (14) having at least one permeable or semi-permeable portion (11), at l...
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WO/2024/030513A1 |
A contact pin printhead for microfluidic array spot printing can include a printhead chassis with a plurality of micro-pins insertable within respective sockets in the printhead chassis. An individual micro-pin can include a micro-pin ti...
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WO/2024/028150A1 |
The present invention relates to a device (1) and its use for receiving a single-use container (44), comprising a receiving container (10) having an interior wall (16) that delimits a container interior of the receiving container (10) fo...
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WO/2024/028407A1 |
A method for producing insect feed is disclosed, the method comprising: passing a gas stream containing CO2 into a solution containing water and algae, harvesting algae from the solution, and processing the harvested algae to produce ins...
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WO/2024/027055A1 |
A kit facilitating querying of reagent tube information, comprising a kit body (1) and a fixed plate (2). A box cover is hingedly connected to the kit body; the fixed plate is fixedly connected to an inner end of the kit body; a movable ...
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WO/2024/029511A1 |
This evaluation method evaluates whether a protein of interest bonds with a target protein and comprises: a step (a) in which a protein of interest, a target protein, a first specific binding substance for the protein of interest, labele...
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WO/2024/028062A1 |
A bioreactor (4) allowing bioprinting inside an interior volume thereof is assembled to form a side wall (SW) extending upwardly from a base provided with a target support (20) for the bioprinting. Once an adapter (5) has been coupled to...
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WO/2024/028063A1 |
The invention concerns a sterile enclosure (2) intended for a printing of a biological three-dimensional structure, the enclosure comprising: - a support (4), - a covering cap (6) comprising a rigid part (22) and a flexible part (24) ext...
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WO/2024/029557A1 |
A controller 44 fixes an antibody 30 or an aptamer to a surface 26 of a base material 20 of a filter 10 by operating a pump 78 in a state where first valves (76c, 76d) are open and a second valve (76a) is closed and passing a first liqui...
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WO/2024/026676A1 |
A preparation system and preparation method for VitroOrganoSpheres with core-shell structure, and a total system. The preparation system comprises a microfluidic chip. A cell fluid flow channel of a shell structure, a cell fluid flow cha...
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WO/2024/028061A1 |
The invention concerns a sterile enclosure (2) intended for a printing of a biological three- dimensional structure, the sterile enclosure comprising : - a rigid top plate (4),5 - a rigid base plate (6) comprising a main face (16) intend...
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WO/2024/028181A1 |
An apparatus (30) for reducing a minimum working volume of a stirred tank (12) includes a body (32) having upper (46) and lower (48) surfaces, and an exterior profile shaped to closely fit within an interior of the stirred tank. The body...
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WO/2024/026229A1 |
A biochip includes a perfusion layer between a media layer and a first membrane. The perfusion layer has a perfusion channel to provide a liquid to cells in a well layer, with the cells attached to a second membrane below the well layer....
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WO/2024/024708A1 |
The present invention addresses the problem of providing a novel composition for cartilage repair including cells that have characteristics suitable for cartilage repair, and a method for producing same. With a focus on umbilical cord ...
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WO/2024/024929A1 |
The present invention relates to a method for producing three-dimensional muscle tissue, the method including the following steps (A) and (B): (A) a step for supplying a myoblast-containing hydrogel to a culture container, the culture co...
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WO/2024/026440A1 |
Provided herein are methods, compositions, kits and systems for the detection, identification and quantification of bacteria and fungi. In particular, provided herein are methods, compositions, kits and systems comprising oligonucleotide...
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WO/2024/024427A1 |
The present disclosure provides a method for determining outer membrane detachment in a cyanobacterium that makes it possible to conveniently determine whether or not the outer membrane of the cyanobacterium has been detached from the ce...
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WO/2024/025052A1 |
A three-dimensional movement mechanical culture system of the present invention includes: a housing; two or more drive wheels installed in the housing and rotating eccentrically; a motion plate provided with a driven wheel rotating betwe...
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WO/2024/021223A1 |
The present application relates to the technical field of exosome extraction, and discloses a method for extracting exosomes. The method comprises the following steps: S1, experiment preparation: placing a sample and a material bearing m...
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WO/2024/024180A1 |
An analysis assistance method for providing assistance in analysis of stained images of a specimen, the method comprising: a step for preparing a plurality of stained images that are obtained by staining a single specimen using different...
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WO/2024/025278A1 |
Provided are a multilayered three-dimensional cell culture formation system and a multilayered three-dimensional cell culture formation method using a multilayered three-dimensional cell culture formation unit according to the present in...
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WO/2024/021164A1 |
The present disclosure relates to a writing system for molecular data storage, comprising: a coded data parsing unit configured to obtain coded molecular module assembly data and parse the molecular module assembly data into a writing pr...
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WO/2024/022874A1 |
A vessel (24) includes an interior volume (25) containing a liquid, a spiral shaft (28) located within the interior volume, and a rotatable impeller (30). The impeller has an aperture (38) that receives the spiral shaft and allows the im...
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WO/2024/024336A1 |
Provided are: a purifying and concentrating device for a liquid comprising a minute useful substance, the device being capable of producing a liquid (purified concentrated liquid of a minute useful substance) comprising a minute useful s...
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WO/2024/023022A1 |
The present invention relates to an optimised photobioreactor device for providing total control of a variable-intensity light source of the device, the intensity being controlled by means of analogue regulation of an LED light source po...
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WO/2024/025891A1 |
Devices and techniques for a system for simultaneous contractile force and calcium/voltage transient measurement of engineered tissue are generally described. The system for simultaneous contractile force and calcium/voltage transient me...
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WO/2024/021222A1 |
The present application relates to the technical field of medical instruments, and provides an exosome extractor, comprising an automatic liquid level detection mechanism, a multi-axis manipulator mechanism, a disinfection and filtering ...
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