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WO/2023/217455A1 |
The invention relates to a measurement device for analysis of a sample contained in a sample holder having an opening, wherein the measurement device is configured to use at least two parallel measurements. The invention further relates ...
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WO/2023/220372A1 |
In an aspect, the present disclosure relates to a method. In one implementation, the method includes providing a material in an air-tight chamber defining an inlet and an outlet; supplying a direct current voltage to an electrode proxima...
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WO/2023/218330A1 |
A method and system for correcting a measurement in a sample analyzing system, the method including receiving a first sample at an interface of the sample analyzing system, the first sample being a portion of a sample source; measuring a...
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WO/2023/218601A1 |
This method for processing a coaxial cable (60) for applying voltage to a time-of-flight mass spectrometer (10) includes a folding processing step S2 and a burying processing step S3. In the folding processing step S2, in a coaxial cable...
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WO/2023/217456A1 |
The invention relates to a measurement system for determining a presence of a chemical substance in a sample. The chemical substance may refer to a simple chemical material or a chemical composition of several compounds. The invention fu...
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WO/2023/214637A1 |
The present invention relates to an integrated FESEM and LDI-TOF-MS analysis system, and provides an integrated FESEM and LDI-TOF-MS analysis system that can perform FESEM analysis and LDI-TOF-MS analysis on a single sample to be analyze...
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WO/2023/209552A1 |
In one aspect, a mass spectrometer is disclosed, which comprises an ion source configured to receive a sample and ionize at least one analyte in the sample to generate a plurality of analyte ions, and at least a first ion routing device ...
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WO/2023/211786A1 |
Systems and methods are described for automatically utilizing multiple data processing methods on a given spectrometry dataset for the determination of nanoparticle detection factors including nanoparticle baseline and detection threshold.
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WO/2023/207159A1 |
Disclosed in the present invention is an ion source cavity, comprising a cavity body. An inner cavity with a bottom opening is provided in the cavity body. A profile sectioned on the inner cavity in any horizontal plane is square. A bott...
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WO/2023/209399A1 |
An aspect of the disclosure provides a spectrometer for detecting a substance of interest, the spectrometer comprising: a chamber through which a number of sample ions travel from an ion gate to a collector electrode; a detector, connect...
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WO/2023/211782A1 |
Systems and methods for iterative removal of outlier data from spectrometry data to determine one or more of a. particle baseline and a detection threshold for nanoparticles are described. Ion signal intensity values that exceed an outli...
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WO/2023/211783A1 |
Systems and methods are described for analyzing local minimum data from spectrometry data for the determination of nanoparticle detection thresholds are described. In aspects, a histogram of the spectrometry' data is used to search for p...
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WO/2023/209596A1 |
A method for performing mass spectrometry comprises generating a plurality of ions from an analyte; directing the plurality of ions into an ion detector to generate a plurality of ion detection signals; generating a plurality of data poi...
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WO/2023/209553A1 |
In one aspect, a method for mass spectrometric analysis of analyte ions is disclosed, which includes filtering a plurality of ions to sequentially transmit a plurality of precursor ion subsets to a charge reduction device (e.g., a proton...
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WO/2023/209594A1 |
In one aspect, a mass spectrometer is disclosed, which includes an ion source configured to receive a sample and ionize at least one analyte in the sample to generate a plurality of ions of that analyte, at least a first ion routing devi...
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WO/2023/203620A1 |
An embodiment of the mass spectrometer according to the present invention comprises: a first LIT (3) which includes multiple electrodes extending along an axis, traps ions derived from a sample into a trapping space surrounded by these m...
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WO/2023/205280A1 |
Methods for enhancing a fluorescence intensity of a sample by adding an aromatic compound thereto. Workflows for a combined fluorescence-MALDI microscopy/imaging instrument also are disclosed comprising combining MALDI imaging and fluore...
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WO/2023/203326A1 |
Methods and apparatus for providing samples to a detector are provided. A detector inlet (100) for providing a sample to an analytical apparatus for detecting a substance of interest comprises a first sampling pathway (102) configured to...
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WO/2023/203621A1 |
One aspect of the present invention is provided with: a LIT (4) that captures specimen-derived ions in a capture space along a linear axis (100) and that emits some of the ions in a direction substantially orthogonal to the axis through ...
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WO/2023/201419A1 |
Systems and method are disclosed that facilitate the controlled collection an aerosol sample from an aerosol plume and the controlled injection of the aerosol sample into an analysis device such as a mass spectrometer. The disclosed embo...
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WO/2023/203541A1 |
In one aspect, a method of performing mass spectrometry is disclosed, which includes selecting a precursor ion having an m/z ratio in a range of interest from among a plurality of ions, identifying a charge state of the selected precurso...
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WO/2023/203545A1 |
In one aspect, a method for monitoring a bias voltage applied to an ion detector of a mass spectrometer is disclosed, which comprises applying an initial bias voltage to the ion detector, using the ion detector with the initial bias volt...
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WO/2023/204187A1 |
A mass spectrometer according to one aspect of the present invention comprises: a LIT (4) that captures ions originating from a sample in a capture space stretching along a linear axis (100) and that emits some of the ions from the captu...
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WO/2023/199273A1 |
In one aspect, a method of operating a high-throughput mass analysis device is disclosed, which includes sampling an unseparated sample from at least one sample holding element during a sampling interval for introduction of the sample in...
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WO/2023/200850A1 |
Disclosed herein are collection probes, devices/apparatuses comprising the same, and methods of use thereof. The apparatuses can comprise: a probe comprising a reservoir, a first conduit, a second conduit, and a third conduit; wherein th...
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WO/2023/199272A1 |
System and method for high-throughput mass spectrometry are disclosed. In some embodiments the system comprises a sample introduction device, an ion source, an ion mobility separation device, a mass analyzer and a controller adapted to r...
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WO/2023/200900A2 |
A tiny and portable micro-spectrometer deployable in a bullet-like form that is inexpensive to the point that it can even be disposable is described. The device is based on the micro-spectrometer that uses the Fresnel diffraction princip...
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WO/2023/199275A1 |
A mass spectrometry system comprises an ion mobility separation device (IMSD) configured to receive a plurality of ions, and to perform an ejection of a set of ions of the plurality of ions by adjusting a set of mobility control paramete...
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WO/2023/200901A2 |
A device and method that creates linear motion or acceleration of fine particles and molecules are described. The device includes a plurality of ring electrodes arranged along an axis so that a cylindrical harmonic field is formed when e...
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WO/2023/193483A1 |
Disclosed in the present invention are an automatic electrospray spraying apparatus and method for preparing a mass spectrum imaging sample. The automatic electrospray spraying apparatus for preparing a mass spectrum imaging sample compr...
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WO/2023/197013A1 |
Disclosed herein are mass spectrometry methods for determining glycoproteoform-based biomarkers. The methods comprise identifying, with a processor from mass spectrometry data of the glycoprotein, a set of glycoproteoforms where each of ...
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WO/2023/193113A1 |
Nav1.5 is the pore forming α-subunit of the cardiac voltage-gated sodium channel that initiates cardiac action potential and regulates the human heartbeat. A normal level of Nav1.5 is crucial to cardiac function and health. Over- or und...
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WO/2023/193481A1 |
Disclosed in the present invention is a micropore oscillation atomization extractive electrospray ionization device for mass spectrum analysis. Droplet collision and extractive ionization occur in an extractive ionization cavity, so that...
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WO/2023/188410A1 |
The present invention provides an analyzing device with which an inflow volume of a gas into a vacuum pump when a power supply to the vacuum pump is stopped can be reduced by means of a simple construction. This analyzing device (100) co...
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WO/2023/184910A1 |
The present invention provides a method and system for automatically tuning an inductively coupled plasma mass spectrometer. In a standard mode, the method comprises: step 101, adjusting the relative position of a plasma flame and a samp...
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WO/2023/180711A1 |
A method of mass spectrometry comprising: a) accumulating precursor ions in a first ion accumulator; b) performing a separation cycle comprising pulsing a packet of the precursor ions out of the first ion accumulator and into an ion sepa...
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WO/2023/181013A1 |
It is proposed to improve transmission of ions along the curved path of an ion guide by changing the separation between adjacent multipole rods in the plane of curvature. As the separation increases along the length of the device, the io...
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WO/2023/180715A1 |
A method of mass spectrometry comprising: a) providing a mass spectrometer having a time of flight (TOP) mass analyser; b) performing a survey scan comprising separating a packet of precursor ion species and mass analysing ions so as to ...
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WO/2023/177731A1 |
Systems and methods are described for transferring gas from an ablation cell to an inductively coupled plasma, analysis system via. a gas exchange membrane transfer line to exchange gas introduced to the ablation cell with a sweep gas. A...
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WO/2023/177736A1 |
Systems and methods are described for controlling flow of a purge gas introduced to an ablation cell between samples to remove atmospheric gas. A system embodiment includes, but is not limited, to, a. spray chamber including a spray cham...
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WO/2023/173305A1 |
The present invention provides a rapid pretreatment-ionization-detection combined device. The device comprises: (a) a fixing device used for fixing a sample to be treated; b) a rapid pretreatment ionization device comprising: a voltage o...
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WO/2023/177745A1 |
A vacuum system is described. The vacuum system includes a vacuum cell and an ion trap. The vacuum cell includes walls having an inner surface that form at least a portion of a vacuum chamber. At least a portion of the inner surface has ...
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WO/2023/172785A1 |
Disclosed herein are electrospray emitter devices for delivering a fluid sample to a mass spectrometer, the emitter devices comprising a sample capillary extending from a sample inlet to a sample outlet said sample capillary defining a p...
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WO/2023/170393A1 |
A mass and/or mobility spectrometer comprising: an ion source enclosure for housing an ion source; a vacuum chamber; a pumping block between the ion source enclosure and vacuum chamber; and a shield for protecting a surface of the ion so...
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WO/2023/170402A1 |
Provided herein are methods and systems directed to stable, isotopically labeled internal calibrators for use in mass spectrometry analysis for quantifying a target analyte in a sample. The present disclosure relates more particularly to...
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WO/2023/171821A1 |
The present invention provides a vibration device which stabilizes vibration of a probe over a long period of time. The vibration device (1) is for causing a cantilever-supported probe to vibrate, said vibration device comprising a probe...
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WO/2023/169770A1 |
Disclosed herein is a residual gas analyser, RGA, for determining the amounts of gas components in a vacuum tool, the RGA comprising a first detector and a second detector, wherein: the first detector is configured so that the largest ga...
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WO/2022/233714A9 |
A time of flight ("TOF") mass spectrometer having: an ion source; a detector; an ion gate positioned on a path extending between the ion source and the detector; a variable voltage unit; and a control unit. The control unit is configured...
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WO/2023/166414A1 |
Systems and methods for performing calibration of compound markers in mass spectrometry (MS) detection are presently claimed and described. The example systems and methods provide for automatic identification of all or substantially all ...
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WO/2023/167937A2 |
In various embodiments alpha helical peptide-based bridges for molecular biosensing "on-chip" are disclosed. The Peptide-based bridges serve as common bridges for great diversity of biosensing applications and targets including nucleic a...
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