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WO/2021/176986A1 |
Provided is a mass spectrometer that further enhances ion transmission efficiency.　This mass spectrometer passes ions generated in an ion source 101 through a vacuum chamber provided with an electrode and transfers the ions to a detect...
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WO/2021/176141A1 |
According to an example aspect of the present invention, there is provided a method for preparing a gaseous isotope reference, the method comprising: providing a solid or liquid carbon-containing material exhibiting a carbon isotope rati...
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WO/2021/175842A1 |
The present invention relates to a method for controlling quality of a mass spectrometry method for detecting one or more target species in a tissue sample. The method in particular relates to a mass spectrometry imaging method. The meth...
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WO/2021/175994A1 |
The invention relates to an instrument comprising a vacuum chamber (10), wherein a wall (17) of the vacuum chamber (10) includes a layer of carbon fiber reinforced thermoset (61) having a thickness in a range of 1-10 mm, a first and a se...
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WO/2021/173934A1 |
A technique for sample analysis includes capturing an image of an analysis location of a sample disposed within a sample chamber using an imaging device having a field of view into the sample chamber along an axis. Subsequent to capturin...
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WO/2021/171936A1 |
This ionization device includes: an ion forming unit that ionizes, using a corona discharge, a substance subject to analysis; and a transport unit that transports, to a mass spectroscopy device, the substance subject to analysis which wa...
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WO/2021/171725A1 |
The purpose of the present invention is to provide an ion source which enables accurate, efficient ascertainment of whether or not the tip position of a capillary on the downstream side is appropriate, and a control method thereof. An io...
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WO/2021/172784A1 |
Provided is a mass spectrometer comprising: an ion generation part for providing an ion generation path; an ion selection part for providing an ion selection path connected to the ion generation path; a reaction part for providing a reac...
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WO/2021/168494A1 |
The invention relates to a method and to an apparatus for measuring the properties of a fluid which flows through a flow channel (2) as a fluid flow. Charge carriers (4) of the fluid are charged in a pulsing manner in a charging unit (3)...
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WO/2021/173853A1 |
A method that includes introducing at least one analyte into a gas plasma; generating neutral species from atoms of the analyte in the gas plasma; preferentially transporting the neutral species downstream of the gas plasma relative to a...
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WO/2021/163755A1 |
Disclosed is a method of providing dielectric barrier discharge ionization, comprising: providing a first and a second electrode which are spaced apart from each other, with a dielectric barrier therebetween; introducing a gas phase of a...
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WO/2021/168111A1 |
Thermal management arrangements for analysis systems including a plasma source such as inductively-coupled-plasma are disclosed. An analysis system may include a plasma source configured to a plasma source configured to receive and ioniz...
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WO/2021/163691A1 |
A method of performing time-of-flight secondary ion mass spectrometry on a sample includes the step of directing a beam of primary ions to the sample, and stimulating the migration of ions within the sample while the beam of primary ions...
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WO/2021/161381A1 |
This mass spectrometry device (100) is provided with: an ionization part (10) including an ionization chamber (1) and an ionization probe (12) for spraying a liquid specimen thereinto; a mass separation part (43) for separating ions in a...
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WO/2021/159861A1 |
A laser coaxial ion excitation device, comprising a light path center and an ion transmission channel. The light path center is hollow, the light path center is coaxial with the ion transmission channel, the ion transmission channel is p...
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WO/2021/161267A1 |
An ion source assembly for use in a mass spectrometry system comprises a housing defining an ionization chamber disposed in fluid communication with a sampling orifice of a mass spectrometer system. The housing defines a first opening fo...
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WO/2021/155647A1 |
A mass spectrometer for particulate matter analysis and a mass spectrometry method. The mass spectrometer may comprise: sequentially coupled, a droplet generation device (103), an ionization device (104), a vacuum interface device (105),...
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WO/2021/156762A1 |
Certain embodiments of ion interfaces are described that can provide higher sensitivities improved ion transmission and multiple operating modes. In some configurations, the ion interface may comprise a first element and a second element...
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WO/2021/157175A1 |
In a mass spectrometer, due to impurities accumulated inside a frame, a withstand voltage may decrease, and electric discharge may occur in an ion source, thereby making it impossible to perform normal measurement. Since the result of ab...
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WO/2021/158596A1 |
A photomultiplier includes a housing including a proximal end and a distal end, an optical window disposed at the proximal end of the housing, an end-wall plate disposed at the distal end of the housing, a feedthrough that penetrates thr...
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WO/2021/158750A1 |
An automated system for lipid exchange-mass spectrometry, e.g., measuring affinity of a membrane protein for lipids. The automated systems herein can measure the specificity of membrane protein-lipid interactions, detect remodeling of th...
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WO/2021/157407A1 |
Provided are: a standard sample film used for a laser ablation inductively coupled plasma mass spectrometry, the standard sample film containing an organic material and having a low variance in signal intensity of ions of a metal element...
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WO/2021/156775A1 |
A method and apparatus are provided for separating and distinguishing between isotopic or isobaric opioid and/or benzodiazepine species within a sample. The method comprises introducing ions of the sample to an inlet of a differential mo...
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WO/2021/155534A1 |
Devices and methods of generating resonance excitation for an ion manipulation apparatus (101) are provided. The ion manipulation apparatus (101) can be operated as an ion filtration apparatus used with particle mass spectrometry system....
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WO/2021/156288A1 |
A device for generating negative ions comprises: a) an ionizer (14) including a heatable ionizer surface; b) a heater (60) for heating said ionizer whereby positive ions (30) are generated at said ionizer surface (14e); c) a target (34) ...
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WO/2021/157142A1 |
Provided by the present disclosure is a spray ionization device comprising: a first tube 21 that has a first flow path 23 through which a liquid can flow and a first outlet 21a on one end thereof from which the liquid is sprayed; a secon...
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WO/2021/158676A1 |
A charge detection mass spectrometer (CDMS) includes an electrostatic linear ion trap (ELIT), a processor, and a memory having instructions stored therein executable by the processor to (a) control the ELIT to trap an ion, (b) collect io...
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WO/2021/151209A1 |
Laser diode thermal desorption coupled with tandem mass spectrometry systems and methods are described to detect at least one target analyte in a sample by negative ion mode mass spectrometry. For instance, the system and method involve ...
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WO/2021/152873A1 |
This mass spectrometry device comprises a sample stage, an irradiation unit, an MCP, a phosphor, an imaging unit, and a control unit. The irradiation unit irradiates a sample with energy rays to ionize a plurality of components of the sa...
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WO/2021/155215A1 |
Disclosed are native liquid chromatography-mass spectrometry systems and methods of use. A native liquid chromatography-mass spectrometry system can include a liquid chromatography system capable of separating a sample; and an electrospr...
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WO/2021/152874A1 |
This imaging unit comprises an MCP, a fluorescent body, and an imaging component. The MCP is disposed on the flight path of an ionization sample, which is a component of an ionized sample, and emits electrons in response to the ionizatio...
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WO/2021/154772A1 |
Spectroferometers and methods of use are provided. The spectroferometers includes an enclosure, one or more interferometer beam- splitting elements, and one or more spectrometer beam-dispersing elements. The one or more interferometer be...
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WO/2021/148371A1 |
Method and system for the identification of compounds in complex biological or environmental samples. The method comprises: receiving (102) a mass spectrum (1) from a mass spectrometry coupled with a separation technique; for each data p...
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WO/2021/149003A1 |
A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the ...
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WO/2021/148714A1 |
An arrangement for providing a waveform for driving an ion mobility device (328). The arrangement comprises at least a plurality of switching circuits (302, 304), each switching circuit comprising at least two switches (306, 308, 310, 31...
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WO/2021/144737A1 |
In one aspect, a mass spectrometer is disclosed, which comprises a Fourier Transform (FT) mass analyzer having an input port for receiving ions and an exit port through which the ions exit the FT mass analyzer, a detector disposed downst...
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WO/2021/144518A1 |
The invention relates mainly to a method for determining the integrity of at least one complex based on at least one biological sample and at least one matrix, comprising at least the following steps: - acquiring at least one image, - an...
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WO/2021/143620A1 |
An in-situ sampling ionization spray kit, comprising a conductive sampling handle upper cover (1) and a kit lower base (2) having a capillary tube-sample storage tank structure. The conductive sampling handle upper cover (1) is used for ...
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WO/2021/143078A1 |
A pulse electrospray ion source, a pulse sample injection method, and a mass spectrum detection system. The ion source comprises a sample supply device, a sample injection capillary tube, and an electrode; a sample solution provided by t...
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WO/2021/144713A1 |
A droplet (415) is ejected from a surface (411) of a fluid sample containing an analyte using an ejector (420). A solvent is pumped into a solvent inlet (432) of an open port probe (OPP) (430) spaced apart from the surface using a pump (...
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WO/2021/143372A1 |
A method and system for regulating the number of ions in an ion trap mass analyzer of a mass spectrometer (10). The method comprises: introducing ions of a sample to be tested into an ion trap (S101); performing initial mass spectrometry...
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WO/2021/144733A1 |
A DMS device receives a curtain gas that includes a chemical modifier into its curtain plate. Before or while receiving ions of an analyte, the DMS device steps the CoV through a series of values in order to apply different CoV values to...
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WO/2021/139404A1 |
Disclosed are a sampling head, a sampling system, a mass spectrum imaging device and a sampling method. The sampling head comprises: a sampling body; a sampling cavity (200), wherein the sampling cavity (200) is provided in a first end f...
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WO/2021/138738A1 |
An example system includes an ion detector and a signal processing apparatus in communication with the ion detector. The ion detector is arranged to detect ions during operation of the system and to generate a signal pulse in response to...
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WO/2021/139412A1 |
A sampling system, a mass spectrometry analysis device, a sampling method, and a mass spectrometry analysis method. By using the sampling system, a controller determines the position of a sampled surface and controls a translation positi...
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WO/2021/140713A1 |
An ionization device 10 used to ionize a sample liquid flowing out from a column of a liquid chromatograph comprises: a conductive probe 12, a voltage application part 6 that applies a prescribed voltage for performing probe electrospray...
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WO/2021/139406A1 |
A sampling head, a sampling system, a mass spectrometry imaging device, and a sampling method. The sampling head comprises a sampling body (100), a tenon (601, 701) being provided on one of two opposite sides of the sampling body (100), ...
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WO/2021/137293A1 |
The invention provides an ion optical device and a mass spectrometer. The ion optical device includes: a power supply device; an ion operation unit composed of a plurality of electrodes electrically connected to the power supply device. ...
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WO/2021/134294A1 |
A voltage suspension control apparatus, a control method, and a time-of-flight mass spectrometer. The voltage suspension control apparatus comprises a power supply and control module (100), an acceleration zone (200), an isolation module...
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WO/2021/131140A1 |
According to an embodiment of the present invention, a MT-TOFM has: a linear ion trap (2) that temporarily holds ions to be analyzed and emits the ions through an elongated ion emission opening (211) in one direction; a go-around flight ...
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