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WO/2022/019815A1 |
A method (300) of reducing the magnitude of a quasi-static electric dipole field at the null position of an oscillating electric quadrupole field of an ion trap (501), the method comprising: • trapping at least one ion (102, 502) in a ...
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WO/2022/020481A1 |
Systems and methods are described for securing fabric, paper, and film samples for analysis by laser ablation, A method embodiment includes, but is not limited to, securing a thin, solid sample with a sample holder system, the sample hol...
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WO/2022/016683A1 |
A laser ionization system for combined use of solid-phase microextraction and time of flight mass spectrometry, comprising a controller (7), a sample pretreatment platform (1), a solid-phase microextraction handle (2), a laser generator ...
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WO/2022/019855A1 |
The present invention relates to a device for determining the mass of a nanoparticle, virus or protein in a suspension or solution in a fluid. This device can be applied in particular to mass spectrometry for ionized species with high co...
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WO/2022/013716A1 |
In one aspect, a method of performing mass spectrometry is disclosed, which comprises ionizing a plurality of oligonucleotides to generate a plurality of negatively charged oligonucleotide ions, and interacting a plurality of charged rea...
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WO/2022/014119A1 |
A gas chromatograph mass spectrometer (1) comprises a gas chromatograph unit (2) for generating a sample gas from an introduced sample and using a separation column (12) to separate the components of the sample gas, a mass spectrometry u...
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WO/2022/013790A1 |
An analyzer and sample handling system suitable for retrieving and processing a sample housed within a suitably configured reaction vessel, and then discarding the used reaction vessel by vertically or axially pushing downward on the ves...
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WO/2022/013715A1 |
In one aspect, a method of performing mass spectrometry is disclosed, which comprises ionizing a sample to generate a plurality of precursor ions, passing the precursor ions through a mass filter to select at least one subset of the ions...
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WO/2022/012701A1 |
A composite mass spectrometer, comprising an ion source, a first ion guide device, a quadrupole mass analyzer, a time-of-flight mass analyzer, a second ion guide device, and a mirror charge detection-based, high-resolution Fourier transf...
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WO/2022/007424A1 |
The present invention relates to the technical field of mass spectra. Disclosed are a novel ion storage system and method based on a quadrupole-ion trap tandem mass spectrometry. The system sequentially comprises a heating capillary, a t...
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WO/2022/009995A1 |
Provided is an electrostatic deflection convergence-type energy analyzer that has a wide acceptance angle and high two-dimensional convergence performance, is capable of imaging a two-dimensional real-space image and an emission angle di...
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WO/2022/011290A1 |
Aspects of the present disclosure describe systems, methods, and structures that enable a compact, UHV ion trap system that can operate at temperatures above cryogenic temperatures. Ion trap systems in accordance with the present disclos...
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WO/2022/008736A1 |
The invention relates to a method for producing a beam of charged gas-phase species based on a composition comprising at least one polymer and at least one precursor species of the beam. The invention further relates to a device for carr...
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WO/2022/009095A1 |
A separation time of an isomer of one or more isomers of a sialylated glycopeptide of a sample is calculated from a peak of a precursor XIC. Product ion intensities of the first group are summed at the separation time producing a first s...
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WO/2022/004051A1 |
A laser light intensity adjustment device 12 emits incident laser light that is linearly polarized laser light at a predetermined intensity, and is provided with: an intensity change optical element (a polarization beam splitter 123) tha...
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WO/2022/006335A1 |
Techniques disclosed herein can be used to perform a rapid, splitless injection of a sample including SVOCs and VOCs. In some embodiments, a system includes two focusing traps combined in series, one inside of a GC oven and one in a sepa...
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WO/2022/004094A1 |
Provided are a micro droplet formation device capable of dividing even small liquid samples, that have been separated by liquid chromatography, into micro droplets with a mean particle diameter of several µm, and an analysis device. A...
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WO/2022/000978A1 |
An aerosol mass spectrometry sampling device having a wide particle size range, and an aerosol mass spectrometer. The aerosol mass spectrometry sampling device comprises: an aerosol delivery tube (10), a first aerosol focusing member (21...
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WO/2021/260374A1 |
A nebuliser outlet comprises an inlet end and an outlet end, a first channel and one or more second channels arranged between the inlet end and the outlet end. The first channel is configured to receive a capillary, and the one or more s...
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WO/2021/254271A1 |
Provided are a traveling monitoring system employing multi-channel technology, and an operation method thereof. The traveling monitoring system comprises a vehicle, a detection device, multiple channels, an enrichment device, a separatio...
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WO/2021/253080A1 |
The invention provides a method for detecting one or more analytes, the method comprising: providing a substrate comprising a semiconductor with a porous surface, wherein the porous surface is coated with a fluorocarbon polymeric coating...
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WO/2021/252325A1 |
A machine, article, process of using, process of making, products produced thereby and necessary intermediates. Illustratively, there can be a process that includes: ionizing at least some injected gas to form ions; confining, without us...
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WO/2021/248178A1 |
The present invention relates to generally to components of scientific analytical equipment. More particularly, the invention relates to apparatus and methods for detecting and quantitating particles, and particularly ions generated in t...
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WO/2021/247358A1 |
A mass spectrometry method comprises generating ions and separating the ions in an ion mobility cell. Some of the generated ions can be contacted with a mobility modifier. The ions can be analyzed with a mass analyzer.
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WO/2021/247820A1 |
An apparatus for ion manipulation having improved duty cycle includes first and second separation regions separated by a switch that alternates between guiding ions to each of the separation regions. The separation regions separate the i...
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WO/2021/240693A1 |
A mass spectrometry method using a mass spectrometer 1 comprising a first movement mechanism 151 for moving a sample stage 14 in a first direction within a plane parallel to the sample stage 14 and a second movement mechanism 152 for mov...
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WO/2021/242103A1 |
An improved ionization source (1) for use with any atmospheric pressure inlet (71) mass spectrometry system (7) is provided herein. The improved ionization source 1 comprises an electrode (2) having a deposition area (21) or a capillary ...
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WO/2021/240158A1 |
A method of operating an ion mobility spectrometer comprises the following steps: drawing a sample of gaseous fluid into a reaction region of the ion mobility spectrometer; providing a first pulse of a pulsed ionisation source to ionise ...
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WO/2021/239692A1 |
A computer implemented method for calibrating a customer mass spectrometry instrument (118) for quantifier-qualifier-ratio check is proposed. The method comprises the following steps: a) at least one manufacturer-site standardization, wh...
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WO/2021/239942A1 |
This method for determining a set of one or more values related to at least one sample using a spectrometry device is implemented by an electronic determination device suitable for being connected to the spectrometry device and comprises...
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WO/2021/240441A1 |
Real-time search (RTS) for mass spectrometry is described. In one aspect, a mass spectrometer can identify a candidate peptide for a product ion spectrum by searching a mass spectral database. Upon determining that a candidate peptide ma...
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WO/2021/242584A1 |
Systems, methods, and computer program products for determining an attack on a neural network. A data sample is received at a first classifier neural network and at a watermark classifier neural network, wherein the first classifier neur...
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WO/2021/234359A1 |
A time-of-flight, TOF, mass spectrometer, MS, comprising: an ion source for supplying a group of ions, including a first ion having a first mass-to-charge ratio m1/ z1, a second ion having a second mass-to-charge ratio m2/z2 and a third ...
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WO/2021/234644A1 |
An ADE device identifies an identifiable sequence of one or more ejections from at least one sample using a different value or pattern of values for one or more ADE parameters. The identifiable one or more ejections are performed to prod...
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WO/2021/234846A1 |
An ion analyzer 1 that controls the movement of ions flowing out from an ion outflow port, the ion analyzer 1 comprising: a substrate 100 having a tubular recess 101 secured to the ion outflow port; a first electroconductive member 153 t...
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WO/2021/233833A1 |
The invention proposes a detection apparatus for detecting charged particles. The device relies on a detection assembly comprising microchannel plates. The useful surface of the microchannel plate device is maximized in time through the ...
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WO/2021/234641A1 |
In a sampling system for mass spectrometry, a method and apparatus are set forth for high flow-rate flushing and sample delivery via a sampling probe (10). The sampling system includes a sampling probe (10) having a first fluid conduit (...
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WO/2021/234646A1 |
Each sample of a series of samples is ejected at an ejection time and according to a sample order. Each ejected sample of the series is ionized, producing ion beam. A list of different sets of MRM transitions is received. Each set of the...
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WO/2021/234360A1 |
A mass spectrometer, MS, 100 is described. The MS 100 comprises: a first chamber 110, comprising a set of ports P close able by respective doors, for receiving sample plates including respective unique device identifiers, UDIs, therein a...
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WO/2021/234645A1 |
An optimal value is calculated for at least one parameter of an ADE device, an OPI, or an ion source device. For each value of a plurality of parameter values for at least one parameter of the ADE device, the OPI, or the ion source devic...
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WO/2021/236379A1 |
A cleanliness monitor, an evaluation system and a method. The cleanliness monitor may include: a first vacuum chamber, a second vacuum chamber, a molecule collector, a release unit, a mass spectrometer, a manipulator that may be configur...
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WO/2021/234674A1 |
In a sampling interface for mass spectrometry, a method and apparatus are set forth for preventing liquid overflow from a sampling probe into a sample. The apparatus comprises a substrate adapted to retain a droplet of liquid as it forms...
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WO/2021/234361A1 |
A mass spectrometer, MS, 100 is described. A mass spectrometer comprises: a set of chambers, for receiving sample plate holders therein and/or therethrough, wherein the sample plate holders are arranged to hold respective subsets of samp...
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WO/2021/233501A2 |
The invention relates to an electron emitter structure comprising: (a) an atmosphere-stable electron emission layer of a mixture of metals having a first side and a second side; and b) an electron accelerating structure on the first side...
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WO/2021/234643A1 |
A trace of intensity versus time values is received for a series of samples produced by a mass spectrometer. Also, a series of ejections times corresponding to the series of samples produced by a sample introduction system is received. A...
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WO/2021/234319A1 |
The present invention relates to a system and a method for analysing VOCs adsorbed on an adsorbent membrane by LTP-MS. The system comprises a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured so...
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WO/2021/229301A1 |
Methods and systems for identifying or classifying charge states of detected ions. An example method for classifying a charge state of detected ions may include generating a pulse for each ion in a plurality of ions detected by a detecto...
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WO/2021/229870A1 |
A door 4 has a blocking part 41 that blocks an opening 302 in a closed state and a holding part 42 that holds the blocking part 41 and is connected to a hinge part 5. The blocking part 41 is coupled to the holding part 42 on the opposite...
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WO/2021/231625A1 |
Embodiments of the present specification provide methods and systems for sensitivity traps that contain a polymer matrix made from an inert polymer material for encapsulation of trace amounts of explosives and narcotics and a suitable pl...
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WO/2021/231398A1 |
The present disclosure relates to an apparatus and method to achieve electrospray ionization at femtoliter/minute to nanoliter/minute flow rates including relatively rapid alternation between such flow rates within the same device. These...
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