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WO/2021/092919A1 |
Disclosed are a nicotinamide mononucleotide intermediate and a method for synthesizing nicotinamide mononucleotide, and the present invention belongs to the field of chemical synthesis. Provided is a method for synthesizing a nicotinamid...
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WO/2021/094459A1 |
The present invention relates to a method for drying human milk oligosaccharides (HMOs). More specifically, the present invention is related to a method of roller drying or drum drying of human milk oligosaccharides in a simple and econo...
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WO/2021/083735A1 |
Method for synthesizing 1,6-anhydro sugars – in particular sugars that may be used as intermediates for making fondaparinux.
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WO/2021/081999A1 |
Disclosed are a low-molecular-weight chondroitin sulfate and a preparation method therefor. Macromolecular chondroitin sulfate is used as a raw material. A low-molecular-weight chondroitin sulfate having an average molecular weight of le...
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WO/2021/083384A1 |
Disclosed are a low molecular weight chondroitin sulfate and a preparation method therefor. The method comprises: using a macromolecular chondroitin sulfate as a raw material, and subjecting same to production processes of chondroitin su...
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WO/2021/075734A1 |
Provided is a method for separating disodium 5'-inosinate from a microorganism culturing medium containing same.
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WO/2021/075882A1 |
The present invention relates to a coagulant that is added to effectively recover a sugar solution from a saccharified product that contains insoluble saccharified residues composed mainly of lignin, and monosaccharides after acidic sacc...
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WO/2021/073064A1 |
A method for improving the yield rate of an Amadori rearrangement product (ARP) on the basis of a mechanism of inhibiting degradation of the ARP by an adduct of a tea polyphenol and deoxyosone. The specific method comprises: dissolving a...
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WO/2021/075904A1 |
The present invention relates to: a newly developed triazine-based amphiphilic compound; a preparation method therefor; and a method for extracting, lysing, stabilizing, crystallizing or analyzing membrane proteins by using same. In addi...
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WO/2021/075423A1 |
The present invention addresses the problem of providing a phosphoramidite activator which improves the solubility of 5-benzylthio-1H-tetrazole in acetonitrile without lowering the yield and purity of a target product. The present inve...
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WO/2021/076630A1 |
In certain embodiments a platform technology for the facilitating immune therapy in the treatement of cancer is provided. In certain embodiments nanocarriers are provided that facilitate delivery of an IDO inhibitor in conjunction with a...
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WO/2021/071890A1 |
The invention relates to methods of synthesizing 2'-deoxy-2',2'-difluorotetrahydrouridine with increased purity and uniform particle size distribution. In particular, methods of the invention include crystallization and isolation procedu...
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WO/2021/072339A1 |
Disclosed is a continuous process for the purification of steviol glycosides such as Rebaudioside D and/or Rebaudioside M extracted from the dried stevia leaves or extracted from a fermentation broth using continuous simulated moving bed...
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WO/2021/069502A1 |
The present invention refers to a method for the production of a catalytically active DNA molecule resulting in a significantly decreased amount of impurities in the catalytically active DNA molecule, to a catalytically active DNA molecu...
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WO/2021/071130A1 |
Provided is a method for preparing a disodium 5'-guanylate heptahydrate crystal from an aqueous 5'-guanylate solution.
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WO/2021/062882A1 |
A method for synthesizing rosavin, comprising the steps of: using trimethylsilyl trifluoromethanesulfonate to catalyze 2,3,4-tri-O-acetyl-L-arabinofuranoside trichloroacetimide ester and ethyl 2,3,4-tri-O-acetyl-beta-D-thioglucopyranosid...
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WO/2021/067970A1 |
The present disclosure provides methods of sequencing polynucleotides and compounds, compositions for sequencing of polynucleotides, and synthesis of such compositions. The chemical compounds include nucleotides and their analogs which p...
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WO/2021/063075A1 |
The present invention relates to the technical field of biomedicine, and disclosed are an albiziae cortex lignan compound and an application thereof. The compound prepared by the present invention can effectively treat FFAs-induced lipid...
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WO/2021/064629A1 |
The present invention relates to the separation and isolation of neutral human milk oligosaccharides (HMOs) from the reaction milieu in which they are produced, preferably from a fermentation broth, comprising the steps of: i) optionally...
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WO/2021/056324A1 |
Provided is a green chemical preparation method for alpha-tri-O-acetyl glucuronic acid methyl ester bromo compound. The method uses sodium bromide, sulfuric acid and methyl tertiary ether system to replace the traditional hydrobromic aci...
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WO/2021/058483A1 |
The present invention relates to processes for producing, isolating and recovering various useful components from solid lignocellulosic biomass. More in particular, the invention provides a process for producing lignin components compris...
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WO/2021/056382A1 |
Provided is a preparation method for alpha-penta-O-acetyl mannose. A study is performed using natural mannose as a raw material on the basis of the conventional acetic anhydride acetylation process. A catalytic amount of cesium fluoride ...
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WO/2021/054474A1 |
In the present invention, a disaccharide unit for synthesizing a useful sugar chain for suppressing the development of dystroglycanopathy is obtained and used to reconstitute a post-phosphoryl sugar chain. Provided are: a disaccharide ...
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WO/2021/042922A1 |
Disclosed is a preparation method for tetragalloylglucose. The method comprises: using Camellia ptilophylla Chang as a raw material for extraction, purifying the Camellia ptilophylla Chang extract by using a macroporous adsorption resin,...
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WO/2021/043540A1 |
Disclosed are non-sporulating Bacillus cells for the production of a sialylated oligosaccharide wherein said Bacillus cell has been genetically engineered to possess a lactose permease, a CMP-NeuNAc biosynthesis pathway and a sialyltrans...
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WO/2021/043631A1 |
The present invention provides new chemical compositions, and methods for their preparation, which are industrially relevant in the manufacture of glycosaminoglycans, particularly fondaparinux.
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WO/2021/039935A1 |
Provided are: a nucleic acid compound manufacturing method that uses a nucleic acid compound that is preserved by a structure in which either one of the third position or fifth position of a ribose structure is represented by formula (1)...
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WO/2021/041728A1 |
The invention relates to a process for producing food ingredients from the Stevia rebaudiana plant and their use in food products, beverages and other consumables. The obtained compositions are useful as flavors, sweeteners, antioxidants...
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WO/2021/041756A1 |
The present invention relates to methods for synthesizing compounds useful as potent and stable RNA interference agents, derivatives thereof, and intermediates thereto.
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WO/2021/031594A1 |
Disclosed are a novel aromatic ring compound represented by general formula (I), an isomer, a prodrug, a solvate, a pharmaceutically acceptable salt and a pharmaceutical composition thereof, and use thereof for preparing medicaments for ...
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WO/2021/034962A1 |
Polymorphic forms of deoxycytidine and methods for preparing the same are provided herein. Also provided are compositions comprising polymorphic forms of deoxycytidine and at least one residual solvent, as well as methods of treating mit...
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WO/2021/034796A1 |
A process is provided for the synthesis of an intermediate of Formula 15 which is useful in the synthesis of E-selectin inhibitors. Also provided are useful intermediates obtained from the process.
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WO/2021/027614A1 |
A modified cytidine compound, that is, an aminooxy group is modified at the 4-position of a cytidine pyrimidine ring to produce derivative cytidine and nucleic acid containing the derivative cytidine, such as RNA. The expression level of...
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WO/2021/022565A1 |
A sucrose fatty acid ester, a preparation method and a quantitative analysis method therefor, and an application thereof. The preparation method comprises the following steps: (1) adding sucrose, a fatty acid methyl ester, a catalyst, an...
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WO/2021/022690A1 |
The present invention relates to the field of chemical synthesis, in relates particular to a nucleoside salt represented by formula (III) or formula (IV), and a preparation method therefor. The method provided by the present invention is...
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WO/2021/022819A1 |
The present invention relates to an isomerization feature-based purification and preparation method of punicalagin. The method uses a pomegranate peel extract as a raw material, avoids impurities contained in punicalagin on the basis of ...
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WO/2021/020879A1 |
The present disclosure provides the dinucleotide compounds which is useful for treating various cancers. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disc...
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WO/2021/019509A1 |
The present document relates to a process for the preparation of the crystalline form II of sotagliflozin from compound of formula (A), said process being continuously performed and comprising at least the steps of: a) performing in a re...
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WO/2021/019507A1 |
The present document relates to a process for the preparation of the crystallineform II of sotagliflozin, wherein said crystalline form II of sotagliflozin is directly obtained from the following compound of formula (A) and by using tolu...
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WO/2021/015622A1 |
The current invention concerns methods for the synthesis of 6-azido-6-deoxy-2-N-acetyl-monosaccharide-nucleoside diphosphate, in particular 6-azido-6-deoxy-2-N-acetyl-D- galactosamine-nucleoside diphosphate or 6-azido-6-deoxy-2-N-acetyl-...
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WO/2021/013795A2 |
The present invention relates to a method of making nicotinamide ribofuranosie salts, in particular pharmaceutically acceptable nicotinamide ribofuranoside salts. The invention further relates to the nicotinamide ribofuranoside salts as ...
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WO/2021/013155A1 |
Disclosed are a new glycosyl donor, a preparation method therefor, and an application thereof. Specifically, a glycosyl donor represented by formula (I), a preparation method therefor, and a use of the glycosyl donor represented by formu...
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WO/2021/008549A1 |
The present invention belongs to the field of pharmaceutical chemistry. Specifically, the present invention relates to a novel compound and a pharmaceutical composition. The novel compound has a structural formula represented by formula ...
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WO/2021/004388A1 |
Crystal form A of a compound represented by formula (I) and an application thereof in preparing a drug for treating an SGLT1/SGLT2-related disease.
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WO/2021/000598A1 |
Provided are a double specific nucleic acid aptamer, a derivative, a preparation method and use thereof, the nucleic acid aptamer comprises a first nucleic acid sequence and a second nucleic acid sequence; the first nucleic acid sequence...
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WO/2021/000380A1 |
The present disclosure relates to the technical field of nucleic acid medicines, in particular to a modified nucleoside, a nucleotide and a modified nucleic acid polymer, as well as a preparation method therefor and an application thereo...
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WO/2020/264055A1 |
The present invention relates to methods for purifying nucleic acids. In particular, the present invention relates to methods for purifying carbohydrate-conjugated oligonucleotides using a mixed-mode stationary phase and a mobile phase c...
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WO/2020/260028A1 |
The invention relates to a process for separating xylose in the liquid phase from a mixture of C5 and C6 sugars comprising at least xylose and glucose, by adsorbing the xylose on a zeolite adsorbent which is based on FAU zeolite crystals...
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WO/2020/260351A1 |
The present invention relates to a process for preparing a compound of formula (I), wherein said process is suitable for large scale synthesis.
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WO/2020/260027A1 |
The invention relates to a process for separating glucose in the liquid phase from a mixture of C5 and C6 sugars comprising at least xylose and glucose, by adsorbing the glucose on a zeolite adsorbent which is based on FAU zeolite crysta...
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