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WO/2018/133600A1 |
Disclosed is a method for preparing high-activity sugarcane anthocyanin. The method comprises: 1) airing and crushing bagasse obtained after juice extraction, and adding distilled water to the bagasse; mixing cellulase, hemicellulase and...
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WO/2018/134343A1 |
The present invention is directed to a compound of formula (III), its preparation and to its use for the preparation of a compound of formula (IV). The present invention hence is directed to a process for the preparation of compound of f...
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WO/2018/129647A1 |
A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containin...
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WO/2018/131711A1 |
The present invention relates to a method for manufacturing a sugar-containing cellulose hydrolyzate, the method including: a step (1) for dissolving cellulose in an acidic aqueous solution; a step (2) for mixing a cellulose-hydrolysis s...
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WO/2018/127236A1 |
Disclosed is a preparation method for (2S,3R,4S)-2,3,4,5-tetrahydroxy-valeraldehyde, which solves the problems in the prior art that reaction conditions are harsh, processes are complex, product yield is low, purity is not high, and indu...
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WO/2018/121559A1 |
A mannuronic dicarboxylic acid oligosaccharide composition, which comprises mannuronic dicarboxylic acid of formula (III) or a pharmaceutically acceptable salt thereof, where n is an integer selected from 1-9, M is selected from 0, 1, or...
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WO/2018/124139A1 |
Provided are: a compound that induces a new type of stereoselective reaction that exhibits stereoselectivity during carbohydrate chain synthesis and produces acetal compounds; a production method for an acetal compound (e.g. a compound h...
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WO/2018/113710A1 |
Provided in the present invention is a method for preparing a β-nucleoside compound, comprising the steps of: 1) performing a silylation reaction of a nitrogenous base or an analogue thereof in the presence of TMSOTf to obtain the nitro...
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WO/2018/115309A1 |
The present invention relates to methods for preparation of glyco-conjugated proteins and in particular to processes for preparation of sugar-nucleotides and modified sugar-nucleotides.
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WO/2018/113592A1 |
The present invention relates to a solid form of a compound of formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and the use of the solid form in the treatment of a disease involv...
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WO/2018/113652A1 |
Provided in the present invention are a compound as shown in formula (I), a pharmaceutical composition comprising same, and a preparation method and use thereof as a NS5B polymerase inhibitor, a DNA polymerase inhibitor or a reverse tran...
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WO/2018/112189A1 |
Methods of preparing novel steviol glycosides are described herein. The methods utilize biocatalysts for converting a starting steviol glycoside to a target steviol glycoside. Compositions and consumables comprising said novel steviol gl...
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WO/2018/107377A1 |
A purification process of NADPH is used for purifying a crude NADPH product obtained by biocatalytic preparation. The present invention resolves the technical problems of existing ion exchange resin methods having low yields and low puri...
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WO/2018/109348A1 |
The present invention relates to a novel method for preparing surfactant compositions made from alkyl-L-iduronamides, alkyl-L-rhamnosides and alkyl-D-glucuronamides, the compositions obtained by said method and the uses thereof.
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WO/2018/105933A1 |
The present invention relates to a method for efficiently utilizing fructose raffinate obtained when separating a psicose conversion reactant with a high-purity chromatograph in a psicose production process. Specifically, the present inv...
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WO/2018/105931A1 |
The present invention relates to a method for preparing psicose by efficiently utilizing a psicose crystallization mother liquor obtained from a crystallization step of psicose and, more particularly, to a method for preparing psicose by...
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WO/2018/103361A1 |
A method for preparing high-purity lactulose by efficient removal of sodium meta-aluminate, pertaining to the technical field of oligosaccharide preparation. The method comprises preparing a high-purity lactulose syrup and a product ther...
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WO/2018/105934A2 |
The present invention relates to a method for efficiently utilizing fructose raffinate obtained from the separation of psicose conversion reactants through high-purity chromatograph in a psicose production process. Specifically, the obje...
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WO/2018/087261A1 |
The invention relates to a process for the synthesis of a product saccharide, preferably of D-allulose from an educt saccharide, preferably from D-fructose under heterogeneous or homogeneous catalysis which includes chemical and/or enzym...
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WO/2018/086330A1 |
The present invention discloses a method for preparing sucralose-6-acylate in a biphasic liquid-liquid system. The method comprises slowly dropwise adding an inert non-polar solvent containing a chlorinating agent to an N,N-dimethyl form...
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WO/2018/089830A1 |
The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X", Z 1, Z2, n, R 1, R2, R3, R4, R5, R6,,R7, and R 8 are described herein, reduced analogs thereof, modified derivativ...
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WO/2018/081557A2 |
crystals are efficiently produced from an allulose syrup using seed crystals.
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WO/2018/069243A1 |
The present invention relates to processes for preparing glucopyranosyl-substituted benzylbenzene derivatives of general formula III, wherein R1, R2 and R' are defined according to claim 1; and the use of such processes in the synthesis ...
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WO/2018/058091A1 |
Described herein are divalent nucleobases that each binds two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone, such as in a γ-peptide nucleic acid (γPNA). Also provided ...
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WO/2018/058150A1 |
Disclosed herein is a method of maintaining corn protein yield during extraction and managing stickiness and viscosity comprising obtaining a corn material having a corn protein content and washing the corn material to remove non-protein...
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WO/2018/053706A1 |
A composition comprises a compound of formula (I) and at least one cosmetically acceptable carrier. It can be used for preventing or decreasing skin pigmentation and /or lightening skin tone.
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WO/2018/052849A1 |
This document provides methods and materials for producing and/or using mitochondrial preparations. For example, methods and materials for using xyloglucan (e.g., xyloglucan material obtained from potato) to produce improved mitochondria...
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WO/2018/053535A1 |
The present invention relates to purified and concentrated human milk oligosaccharide compositions and methods of making and using the same.
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WO/2018/050099A1 |
Provided is a panaxdiol-type ginsenoside derivative having a structure as shown in formula I or formula II. Also provided is the use thereof in the preparation of a drug for preventing and treating atherosclerosis. The panaxdiol-type gin...
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WO/2018/045997A1 |
The present application falls within the field of drug synthesis, and relates to a method for preparing 2-fluoro-2-methyldeoxynucleoside as an intermediate of Sofosbuvir. In particular, the present application provides a method for prepa...
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WO/2018/039923A1 |
A preparation method of diosmin, comprising: A) mixing an amide solvent, hesperidin, an alkaline reagent, with iodine, and heating to react to obtain diosmin. Compared with the prior art, the amide solvent used as a reaction solvent has ...
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WO/2018/042464A1 |
The present disclosure provides a process for rapid hydrolysis of a substrate the process comprises the steps of obtaining a substrate slurry; contacting the 10 substrate slurry with at least one enzyme to obtain a soluble fraction and a...
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WO/2018/032272A1 |
A novel method for preparing an important bioactive substance, oligomeric mannuronic diacid. The method uses oligomeric mannuronic acid as the starting material and obtains the target substance by means of steps of acid degradation and a...
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WO/2018/033639A1 |
The present invention is directed to lactones of the following structural formula for use as precursors of NAD, and their use as nutritional supplements.
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WO/2018/033676A1 |
The invention relates to a frozen dessert with a reduced sugar content, more particularly ice cream with reduced sugar. The invention also relates to the use of maltooligosaccharides for replacing some of the sugar contained in a frozen ...
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WO/2018/035050A1 |
Hypersulfated disaccharides with utility in asthma or asthma related disorders are disclosed. The heptasulfated disaccharides administered orally have comparable bioavailability to the intravenous administered dosage form.
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WO/2018/033677A1 |
The invention relates to dairy compositions having a low sugar content and organoleptic and rheological properties similar to standard dairy compositions. The invention also relates to the use of maltooligosaccharides for replacing some ...
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WO/2018/030698A1 |
The present invention provides a method for electrochemically converting aldose into a ketone compound, comprising the steps of: performing a reduction reaction on aldose through an electrochemical catalytic reaction in the presence of a...
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WO/2018/029272A1 |
A method for purifying rebaudioside M, which method comprises: (a) providing a solution comprising rebaudioside M at a concentration of at least about 10g/L and at a purity of at least about 10% by weight on a dry basis; and (b) crystall...
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WO/2018/028494A1 |
A gemcitabine ProTide hypoxic-activated prodrug and a use thereof in the preparation of a medicament for treating tumors. The general structural formula thereof is formula (A), wherein: one of R1 and R2 is a hypoxic-activated group of -C...
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WO/2018/028050A1 |
Disclosed is an asymmetric aryl-alkyl persulfate compound as represented by formula (3) and a synthesis method therefor, in which an arylboronic acid of formula (1) and R2SSCOR3 of formula (2) serve as reaction raw materials and, under t...
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WO/2018/029274A1 |
A method for purifying rebaudioside A, which method comprises: (a) providing a solution comprising rebaudioside A; (b) concentrating the said solution; and (c) crystallizing from the solution a high purity composition comprising rebaudio...
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WO/2018/023205A1 |
A purification method for nicotinamide mononucleotide, relating to a method for purifying an NMN crude product obtained via a biocatalysis method. The purpose of the present method is to solve the problems in existing NMN purification me...
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WO/2018/019748A1 |
The invention relates to a compound of formula (I) wherein R2 and R4 are joined and together form a group, such a -CH2O-. The compound of formula (I) can be used in the manufacture of 5'S-LNA oligonucleotides as antisense drugs.
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WO/2018/019188A1 |
Provided are a crystal form A of a nucleoside phosphoramidate prodrug as shown in formula I and a preparation method therefor. The crystal form A at least has an X-ray powder diffraction (XRPD) pattern with peaks at the 2θ angles of 6.9...
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WO/2018/014866A1 |
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-eth
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WO/2018/010170A1 |
Provided is a novel embodiment of a flavonoid with reduced hygroscopicity and improved storage stability. The flavonoid is applicable for preparing a food, health food, or pharmaceutical product or composition thereof to provide preventi...
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WO/2018/011067A2 |
Disclosed herein are novel processes for the production of oligonucleotides that are suitable for use in the production of chemically modified oligonucleotides, such as those for use in therapy.
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WO/2018/007035A1 |
The present invention relates to a process for the purification of methylcobalamin, namely from iron cyanide impurities, comprising contacting a solution comprising methylcobalamin and iron cyanide anions with a strongly basic anion exch...
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WO/2018/005630A1 |
The invention provides a compound of the formula (I), and a capture support of the formula (9), wherein R1, R2, R3, R6, A, B, D, E, J, K, Q, W, and Z are as defined herein. The invention also provides a method of purifying an oligonucleo...
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