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Title:
METHOD FOR INCREASING FERMENTATION YIELD OF PF1022A
Document Type and Number:
WIPO Patent Application WO/2023/222075
Kind Code:
A1
Abstract:
The present invention provides a method for increasing a fermentation yield of PF1022A. By using a Rosellinia sp. strain that can produce PF1022A as a production strain, aerobic fermentation is carried out in a fermentation medium. The fermentation medium comprises an assimilable carbon source, an assimilable nitrogen source, and an inorganic salt, wherein the assimilable carbon source contains a solid malt extract. The technical solution provided by the present invention is simple and easy to implement, improves the production efficiency of PF1022A, increases the yield of PF1022A, and reduces the production cost, thus facilitating the large-scale industrial production preparation method of PF1022A.

Inventors:
XU QIAN (CN)
XIANG RENXIN (CN)
YANG XIAOHU (CN)
FANG JIASHUANG (CN)
TAO LIANGLIANG (CN)
YING LINGPING (CN)
SUN PENG (CN)
YANG ZHIQING (CN)
Application Number:
PCT/CN2023/095010
Publication Date:
November 23, 2023
Filing Date:
May 18, 2023
Export Citation:
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Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C12N1/14; C12P17/14; C12N1/38; C12R1/645
Foreign References:
CN114875093A2022-08-09
CN109880746A2019-06-14
CN110964646A2020-04-07
CN107217007A2017-09-29
CN107217008A2017-09-29
CN108570016A2018-09-25
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