Title:
COMPOSITION FOR IMPROVING MOLECULAR BARCODING EFFICIENCY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/181858
Kind Code:
A1
Abstract:
The present invention relates to a composition for improving molecular barcoding efficiency and a use thereof, and provides a method for preparing a DNA library, a molecular barcoding method for nucleic acid sequence analysis, and a composition for preparing the DNA library. According to the methods and the composition, the phenomenon of molecular barcoding substitution can be reduced, and the accuracy of nucleic acid sequence analysis can be improved by using a barcode sequence arranged, on the basis of the terminal region of an adapter which is ligated with a DNA fragment, to include a first nucleotide position in the adapter.
Inventors:
PARK DONG HYUN (KR)
CHUNG JONG SUK (KR)
SHIN SEUNG HO (KR)
KIM SOL YI (KR)
LIM HYE YEUN (KR)
PARK HYEONG BEEN (KR)
CHUNG JONG SUK (KR)
SHIN SEUNG HO (KR)
KIM SOL YI (KR)
LIM HYE YEUN (KR)
PARK HYEONG BEEN (KR)
Application Number:
PCT/KR2021/002492
Publication Date:
September 01, 2022
Filing Date:
February 26, 2021
Export Citation:
Assignee:
GENINUS INC (KR)
International Classes:
C12Q1/6806; C12Q1/6855; C12Q1/6869
Foreign References:
| KR20160141680A | 2016-12-09 | |||
| KR20170133270A | 2017-12-05 | |||
| KR20140111224A | 2014-09-18 | |||
| KR20130018575A | 2013-02-25 | |||
| US20150284712A1 | 2015-10-08 | |||
| US20200123538A1 | 2020-04-23 |
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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