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WO/2023/013274A1 |
A mass spectrometer including: a mass filter comprising rod electrodes 37, a holder 38 holding the rod electrodes, a holder support 39 on which the holder is placed, and a flat spring 43 that pushes and secures the holder against the hol...
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WO/2023/007820A1 |
This mass spectrometer (1) comprises: a roughing vacuum pump (30); a turbomolecular pump (40); a first chamber (21) in which exhausting is performed by the roughing vacuum pump (30); a second chamber (22) positioned at the rear stage of ...
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WO/2023/002282A1 |
An analytical instrument produces intensity versus time measurements or intensity versus m/z measurements for each acquisition of n acquisitions using m instrument parameter values for each acquisition of n acquisitions, wherein n is a n...
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WO/2023/000094A1 |
A system for cooling an inductively coupled plasma (ICP) instrument includes: the ICP instrument; a pump in fluid communication with the instrument via a first conduit; and a micro-channel heat exchanger in fluid communication with the i...
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WO/2023/002712A1 |
A mass spectrometry method according to the present invention comprises: introducing precursor ions into a reaction chamber (step 2); generating radicals in a radical generating chamber; generating product ions by irradiating the precurs...
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WO/2023/002168A1 |
A method of mass spectrometry comprising: mass analysing ions with a mass analyser so as to obtain first mass spectral data; summing the first mass spectral data obtained during a first integration period; obtaining a transmission profil...
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WO/2023/288179A1 |
A method for optimizing an electrostatic linear ion trap (ELIT) for mass-to-charge (m/z) measurement resolution may include determining initial electrostatic and geometric parameters of the ELIT, modifying at least one of the initial ele...
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WO/2023/285427A1 |
A target (110) for use in a laser desorption mass spectrometer is disclosed. The target (110) has at least one surface (112). wherein the surface (112) is covered at least partially with at least one layer (114), wherein the layer (114) ...
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WO/2023/283726A1 |
The present system is a filament and an ion guide configuration. The ion source and an ion guide are combined in one system to create a fast release of ions, with increased efficiency of ion transport. The present device is a high-effici...
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WO/2023/285791A1 |
A multi-reflecting time of flight mass spectrometer (8) comprising: a mass filter or mass separator (6); an ion accelerator (14) for pulsing packets of ions; ion mirrors (10) arranged to receive the ions from the ion accelerator (14) and...
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WO/2023/285802A1 |
An ion guide assembly for a mass spectrometer is described. The ion guide assembly comprises a collision / reaction cell, CRC, comprising an enclosure having a first multipole RF ion guide enclosed radially therein and a set of gas inlet...
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WO/2023/286537A1 |
In order to reduce the effect of disturbance propagation noise inside and outside a signal detection device and improve signal detection accuracy, the present disclosure provides a signal detection device comprising: a detector that incl...
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WO/2023/282149A1 |
The objective of the present invention is to perform analysis covering a wide range of mass-to-charge ratios using a smaller number of measurements than in the past. A mass spectrometry device (1) comprises: a time of flight measuring un...
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WO/2023/282061A1 |
This mass spectrometry method comprises: (11) forming, on a sample plate, a mixed crystal of a matrix material and a microorganism sample, which is a sample including a subject microorganism or a component derived from the subject microo...
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WO/2023/281159A1 |
The present invention relates to sampling systems (100), wherein the sampling is based on removal of material from a sample immersed in a fluid by cavitation induced by high-intensity focused ultrasound (HIFU). The system comprises also ...
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WO/2023/283236A1 |
A multi-atomic object crystal is transported from a first leg (110B) to a second leg (110C) of an atomic object confinement apparatus (100) through a corresponding junction (120). Voltage sources in electrical communication with electrod...
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WO/2023/281387A1 |
One or more known compounds are separated from a mixture using a separation device that allows processor-controlled adjustment of a separation parameter. The separated compounds are ionized and, for each cycle of a plurality of cycles, a...
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WO/2023/278543A1 |
The present disclosure is directed to an ion funnel and associated systems, where the ion funnel includes a plurality of electrodes each define an opening having an associated inner dimension and receive a RF voltage. The associated inne...
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WO/2023/275694A1 |
Methods and systems for delivering a liquid sample to an ion source for the generation of ions and subsequent analysis by mass spectrometry are provided herein. In accordance with various aspects of the present teachings, MS-based system...
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WO/2023/275693A1 |
The present disclosure provides methods and systems for performing mass spectrometry in which at least two batches of precursor ions generated via ionization of at least two different portions of a sample are exposed to electron beams at...
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WO/2022/268650A1 |
A method of calibrating a mass spectrometer is provided. The method comprises generating calibration ions from an ion source. The calibration ions are transported from the ion source to a mass analyser of the mass spectrometer via an ion...
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WO/2022/269565A1 |
The technology relates to systems and methods for performing mass spectrometry analysis of a sample. An example method may include receiving, as input via an input device, a target mass-to-charge (m/z) ratio for a fragment ion of interes...
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WO/2022/270729A1 |
The present invention relates to a collector for an ion mobility spectrometer and, more specifically, to an ion collector in which ionic substances collide in order to analyze the ionized substance. To this end, the ion mobility spectrom...
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WO/2022/270469A1 |
In order to achieve reduction in size, this mass spectroscope is characterized by comprising: an ion source (200) for continuously generating ions (23); a pre-trap chamber (130) capable of trapping the ions (23); an ion trap chamber (140...
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WO/2022/269414A1 |
In one aspect, a method for performing mass spectrometry is disclosed, which comprises passing a plurality of ions from an upstream ion guide to a downstream ion guide through an aperture of an ion lens disposed between the ion guides, a...
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WO/2022/269471A1 |
Systems and methods are disclosed for RF amplitude auto-calibration for mass spectrometry. As non-limiting examples, various aspects of this disclosure provide in a mass spectrometer comprising an RF gain block, a peak detector, and a co...
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WO/2022/269262A1 |
There is provided a mass and/or mobility spectrometer (200) comprising: a vacuum housing (210) having a first vacuum chamber (212) therein; and a first vacuum pump connected to said first vacuum chamber (212) by a conduit (216); wherein ...
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WO/2022/264093A1 |
In one aspect, an electron capture dissociation (ECD) device for use in a mass spectrometer is disclosed, which is configured to trap precursor ions and cause the trapped precursor ions (or a portion thereof) to exit the ion trap, via ra...
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WO/2022/262954A1 |
A method of processing an image-charge/current signal representative of one or more ions undergoing oscillatory motion within an ion analyser apparatus, the method comprising obtaining a recording of the image-charge/current signal gener...
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WO/2022/262957A1 |
A method of processing an image-charge/current signal representative of one or more ions undergoing oscillatory motion within an ion analyser apparatus. The method comprising obtaining a recording of the image-charge/current signal gener...
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WO/2022/261399A1 |
This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having a monoclonal or oligoclonal gammopathy of thrombotic/thrombocytopenic significance (MGTS). For example, the presence of a populati...
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WO/2022/259405A1 |
An embodiment of a TOFMS according to the present invention comprises: flight-space-forming electrodes (11, 12) that form a flight space for separating ions derived from components contained in a sample according to m/z; an ion detection...
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WO/2022/259186A1 |
In one aspect, a method of introducing a sample into an open port interface (OPI) of a mass spectrometer is disclosed, which includes mixing the sample with a solvent in which a matrix of an aqueous phase of the sample is immiscible and ...
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WO/2022/259201A1 |
Systems and methods described herein provide for the injection of ions into an ELIT at a variety of kinetic energies such that the ions turn around at various locations. In certain aspects, such systems and methods for operating an ELIT ...
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WO/2022/259187A1 |
In one aspect, a calibration system for use in a mass spectrometer having an open port interface (OPI) for receiving a sample for mass analysis is disclosed, which includes a fluidic junction having a first inlet in fluid communication w...
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WO/2022/259102A1 |
During each time cycle, a precursor ion transmission window is stepped in k overlapping steps that are Δm m/z apart entirely across a mass range from a starting m 1 m/z. The window is stepped n ̵ 1 more times starting at n ̵ 1 differe...
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WO/2022/258556A1 |
There is provided a method of identifying one or more molecular species represented in a mass spectrum. The method comprises obtaining a set of candidate mass spectra for the mass spectrum, wherein each candidate mass spectrum correspond...
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WO/2022/256941A1 |
A controller for an open port interphase mass spectrometry (MS) probe automates analysis of samples, providing continuous, fast, and reproducible sampling. The sensed position of the probe above the sample surface is used by the controll...
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WO/2022/258966A1 |
A mass and/or ion mobility spectrometer comprising: an ion source enclosure; a first vacuum chamber in fluid communication with said ion source enclosure via a first orifice; an isolation valve for at least partially closing said first o...
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WO/2022/254266A1 |
Method and ion trap for detecting ions, wherein the method comprises the steps of Ionizing ions in the ion trap; Creating an RF storage field by applying a first RF signal to a first electrode of the ion trap; Applying an excitation sign...
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WO/2022/254404A1 |
A system for analyzing a sample includes a sample preparation sub-system for preparing at least one sample in a sample vessel and a magnetic bead storage sub-system. A sample intake sub-system receives the at least one sample. A mass spe...
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WO/2022/252801A1 |
An ion trap integrated chip and a preparation method therefor, and an ion trap quantum computing system. The ion trap integrated chip comprises a trapping electrode, a metasurface structure, and a conveyance assembly; the trapping electr...
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WO/2022/253838A1 |
An analyzer system (110) is disclosed. The analyzer system (110) comprises: • at least one mass spectrometry device (112) having at least one electrospray ion source nozzle (114); • at least one liquid supply (116), wherein the liqui...
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WO/2022/254526A1 |
An embodiment of the quadrupole-type mass spectrometer according to the present invention comprises: a main rod unit (500) that has a quadrupole mass filter that separates ions to be measured by m/z value, the quadrupole mass filter incl...
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WO/2022/256295A1 |
A method for detecting radicals in process gases in a semiconductor fabrication assembly is provided where the semiconductor fabrication includes a plasma source and a mass spectrometer with an ion source. The method includes separating ...
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WO/2022/249624A1 |
This mass analysis device (1) comprises: a housing part (33) which has a wall section (33a) and is provided with a mass analysis unit (30); a base part (70); a sampling unit (20) which is detachably attached to the base part (70); and a ...
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WO/2022/251460A1 |
A Taylor cone emitter device is disclosed, including a substrate, a sorbent layer on at least a portion of the substrate, a Taylor cone emitter portion extending from the substrate, and a reservoir surface configured to retain a liquid a...
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WO/2022/251432A1 |
The invention generally relates to systems and methods for focusing ions using counter flows of opposite or like charged ions. In certain embodiments, oppositely charged ions are introduced in a counter flow to a target ion beam within a...
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WO/2022/247246A1 |
The present invention relates to the technical field of biomedical treatment. Disclosed is a sample loading device for a mass spectrometer. The sample loading device is provided at a sample inlet side of the mass spectrometer. The sample...
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WO/2022/249291A1 |
The PESI mass spectrometry device according to an embodiment of the present invention comprises: a PESI ion source (103, 104, 106, 107); a mass filter (140) that selects specific ions from ions produced by the ion source; a collision cel...
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