Title:
SAMPLE LOADING DEVICE FOR MASS SPECTROMETER
Document Type and Number:
WIPO Patent Application WO/2022/247246
Kind Code:
A1
Abstract:
The present invention relates to the technical field of biomedical treatment. Disclosed is a sample loading device for a mass spectrometer. The sample loading device is provided at a sample inlet side of the mass spectrometer. The sample loading device comprises a microfluidic chip, a connecting pipeline, a spray needle, and a sample injection structure; the sample injection structure injects a sample to be tested and a reaction solution into the microfluidic chip; one end of the connecting pipeline is connected to an outlet end of the microfluidic chip; the spray needle is connected to the other end of the connecting pipeline and is connected to a power supply, and a sample solution is formed into spray in an electrospray manner; the spray needle generates the spray for being sprayed into a sample inlet of the mass spectrometer. On the one hand, the device can be adapted to a commercialized mass spectrometer to achieve online sample high-efficiency mixing-mass spectrum sample injection and accurate regulation and control of reaction time after mixing, and is suitable for real-time mass spectrum characterization of a sample dynamic process at different time points in a specific biochemical reaction; on the other hand, a special interface form is used, so that connection is tight without liquid leakage, ionization efficiency and sensitivity are high, dead volume is small, and replacement is convenient.
Inventors:
MEN YONGFAN (CN)
WANG GUANBO (CN)
LI WEN (CN)
CHAIHU LINGXIAO (CN)
WANG GUANBO (CN)
LI WEN (CN)
CHAIHU LINGXIAO (CN)
Application Number:
PCT/CN2021/139303
Publication Date:
December 01, 2022
Filing Date:
December 17, 2021
Export Citation:
Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
H01J49/04
Foreign References:
| CN113327836A | 2021-08-31 | |||
| US20040229377A1 | 2004-11-18 | |||
| CN103033556A | 2013-04-10 |
Attorney, Agent or Firm:
BEIJING ZHONG XUN TONG DA INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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