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WO/2004/016625A2 |
Methods for forming organosilicon esters and amides are provided. Additionally, organosilicon esters and amides are provided. The organosilicon esters and amides may be formed by contacting a hydrolase enzyme with an organosilicon reacta...
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WO/2003/103625A2 |
The invention relates to method and compositions based on unsaturated metabolic phospholipids for the treatments of wrinkles and striae distensae. Said phospholipids were found to be useful to manufacture effective anti-wrinkle topical c...
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WO/2003/102217A2 |
The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, a...
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WO/2003/083123A2 |
The invention relates to an improved method for producing vitamin B12, according to which a culture containing a microorganism in which at least the enzymes uroporphyrinogen-III-methyltransferase and precorrin-2-dehydrogenase that are in...
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WO/2003/074718A1 |
The invention relates to a process for preparing organosilicon group containing photoinitiators of the formula (I), wherein m is a number from 1 to 200; q is 0 or 1; A is IN-C(O)-O-CHR3-Y- or IN-C(O)-NH-CHR3-Y-; A’ is A or R1’; R1 an...
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WO/2003/072792A2 |
A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non−phytotoxic substance to produce a phytotoxic one, a...
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WO/2003/054205A2 |
Processes for making siloxanes, more particularly biosynthetic processes for making cyclic siloxanes are provided by the present invention.
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WO2002079395A9 |
Membranous bacteria that produce astaxanthin and other carotenoids are described, as well as isolated nucleic acids and expression vectors that can be used for producing carotenoids in microorganisms.
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WO/2003/042392A1 |
A standardised and optionally hydrogenated phospholipid composition comprising a phospholipase modified and the corresponding unmodified phospholipid and optionally other components obtainable by a method comprising: i) Modification of a...
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WO/2003/023033A1 |
A monoxygenase comprises: (a) CYP101 having the mutations L244A and V247L; (b) a homologue thereof in which the equivalent amino acids to L244 and V247 have been substituted to increase the coupling efficiency or oxidation rate of pentac...
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WO/2003/020941A1 |
The invention relates to a method for the production of phospholipids of general formula (I) with the exclusive aid of phospholipase D from a phospholipid mixture and without using organic solvents, wherein phosphatidyl acid is produced ...
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WO/2003/010294A2 |
The instant invention relates to bioproduction of isopentenyl diphosphate within the latex of the rubber tree, Hevea brasiliensis. Isopentenyl diphosphate (IPP) synthesis from acetate is mediated by a set of enzymes encoded by six genes ...
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WO/2003/008546A2 |
Pure bacterial cultures for the production of formylphosphonic acid (FPA) by the oxidation of hydroxymethylphosphonic acid (HMPA) are provided. The cultures can be used to bioremediate HMPA contaminated wastewater or soil, or can be used...
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WO/2002/095011A2 |
The invention relates to cells and organisms as well as to methods for producing said cells and organisms, according to which intermediates of the mevalonate-independent pathway for isoprenoid biosynthesis (MEP pathway) are enriched by d...
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WO/2002/090560A2 |
The present invention provides a new enzymatic process for preparing 1,2-diacylated phospholipids comprising the use of an enzyme preparation possessing phospholipase activity towards acylation at the sn-1 and sn-2 sites in a microaqueou...
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WO/2002/083720A2 |
The invention provides a protein in a form that is functional for the enzymatic conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate to 1-hydroxy-2-methyl-2-butenyl 4-diphosphate notably in its (E)-form of the non-mevalonate biosynt...
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WO/2002/064603A1 |
The present invention concerns a process for the preparation of pure phosphatides starting from mixtures of natural phosphatides, or their single components, such as soybean or egg lecithin or animal phospholipids, or from synthetic phos...
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WO/2002/029009A1 |
Methods and materials are provided for stably introducing any gene into a specific locus in the genome of a microorganism such as yeast without the addition of any drug resistance genes. Specifically provided herein are new genetically e...
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WO/2002/022842A1 |
The invention relates to a method for the polycondensation of organic silicon compounds at pH values between 6 and 8 in the presence of a lipase, said lipase being optionally immobilised on a carrier consisting of polymer materials. Suit...
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WO/2002/012532A1 |
A process for the production of phospholipids by transphosphatidylation, which comprises the step of mixing a starting phospholipid with a receptor having one or more hydroxyl groups, phospholipase D and water in the absence of an organi...
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WO/2002/006491A1 |
A novel isopentenyl pyrophosphate isomerase; and a gene coding for the same. An enzyme protein having the following physicochemical properties and having an isopentenyl pyrophosphate isomerase activity is provided. Function: It isomerize...
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WO/2001/094561A2 |
The present invention is directed to enzymes and intermediates of the non-mevalonate isoprenoid pathway downstream of 2C-methyl-D-erythritol 2,4-cyclopyrophosphate and upstream of isopentenyl pyrophosphate or dimethylallyl pyrophosphate....
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WO/2001/083497A1 |
The invention relates to compounds of the general formula (I), wherein R?1¿, R?2¿, E, X¿1?, X¿2? and X¿3? have the definitions in this application, obtained by the cultivation of the $i(Streptomyces) species HAG 004107 (DSM 13381) a...
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WO/2001/079463A2 |
The present invention relates to isolated nucleic acid sequences encoding polypeptides having more than 50 % residual haloperoxidase activity after 15 minutes incubation at 70 degrees centrigrade and pH7. The invention also relates to nu...
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WO/2001/079460A2 |
The present invention relates to isolated polypeptides having haloperoxidase activity more than 50 % residual activity, after 15 minutes incubation at 70 °C an pH7. The invention also relates to methods for producing and using the polyp...
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WO/2001/040496A1 |
Disclosed herein is a method for purifying the lysophosphatidylethanolamine with high purity by treating the phospholipid mixture with enzymes, followed by solvent fractionaltion without the column purification. The method of the present...
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WO/2001/014566A2 |
The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
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WO/2000/077183A1 |
Methods of conducting phospholipase-catalyzed transesterification or hydrolysis of phospholipids present in aqueous liposomal suspensions, in the absence of detergents and organic solvents, are described. The method, which employs a wate...
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WO/2000/058281A1 |
Substrates for thioredoxin reductase, containing compounds represented by general formula (1) or (1') (such as 2-phenyl-1,2-benzisoselenazol-3(2H)-one or open-ring derivatives thereof) (wherein R?1¿ and R?2¿ are each hydrogen, halogeno...
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WO/2000/053792A1 |
Novel substances WK-5344A and WK-5344B having an effect of inhibiting cholesteryl ester transfer protein; and a process for producing the same which comprises culturing a microorganism belonging to the genus Streptomyces and being capabl...
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WO/2000/032758A1 |
The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a desired activity or to decrease the level of a...
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WO/2000/018945A1 |
A method for transphosphatidylation which comprises reacting a phosphatidylcholine donor with a nucleophile in a nonaqueous solvent in the presence of a cation exchange resin, wherein the resin binds choline formed as a byproduct of the ...
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WO/2000/001650A1 |
The invention provides a method of producing $g(a)-tocopherol and $g(a)-tocopheryl esters and a method of producing vitamin A or $g(b)-carotene. The methods comprise using a biological system to produce farnesol or geranylgeraniol. Then,...
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WO/2000/001649A1 |
The invention provides a method of producing $g(a)-tocopherol and $g(a)-tocopheryl esters. The method comprises using a biological system to produce farnesol or geranylgeraniol. Then, the farnesol or geranylgeraniol is chemically convert...
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WO/2000/001685A1 |
The invention provides methods for producing tocopherol compounds of the Vitamin E family by reduction of various 4-chromanone trienol materials. In preferred embodiments the invention provides methods of preparing and hydrogenating 4-ch...
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WO/2000/001686A1 |
The invention provides processes for producing phytol, isophytol, and certain phytol derivatives by a method of oxidizing or epoxidizing geranylgeraniol or geranylgeraniol derivatives to form epoxygeranylgeraniol derivatives, reducing or...
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WO/1999/058643A1 |
A microorganism belonging to the genus $i(Psychrobacter) and producing docosahexaenoic acid; a liquid culture medium of this microorganism having a phospholipase A¿1? activity; a process for preparing a phospholipid being rich in docosa...
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WO1999043791A9 |
The invention relates to diisopropyl fluorophosphatase (enzyme classification EC 3.1.8.2.) from Loligo vulgaris and to the base sequence which codes the enzyme. The invention also relates to the additional vectors which contain the inven...
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WO/1999/032638A1 |
A process for easily producing dihydroxyacetone 3-phosphate at a high concentration, which comprises treating dihydroxyacetone with a bacterium transformed by a dihydroxyacetone kinase gene or the kinase produced by this bacterium.
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WO/1999/031254A1 |
Geranyl diphosphate synthases having an amino acid sequence derived from the amino acid sequence of farnesyl diphosphate synthase by the substitution of the amino acid at the 82-position by another amino acid having a molecular weight la...
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WO/1999/006585A1 |
This invention provides a particulate material suitable for use as a nutritional supplement, particularly as an aquaculture feed. The particulate material has a high proportion of DHA residues in the lipid fraction, which may be up to 35...
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WO/1998/050523A1 |
Methods are provided for increased and controlled production of choline and inositol, choline and inositol metabolites, and choline- and inositol-containing phospholipids in yeast, comprising the step of increasing phosphatidylcholine (P...
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WO/1998/022479A1 |
A compound of formula (1), particularly where X = O, Y = NR?1�R?2�, wherein R?1� = R?2� = H and Z?1� = Z?2� = OH, can protect and/or aid the recovery of functionally impaired tissue whose viability is threatened by hypoxia. T...
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WO/1998/020138A1 |
A mutant prenyl diphosphate synthase having a modified amino acid sequence of prenyl diphosphate synthase, wherein the amino acid residue located at the eighth position in the N-terminal direction from D of the N-terminal of the Asp-rich...
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WO/1998/006856A1 |
The present invention relates to phytase or a functional derivative thereof having a specific activity of at least 20 U/mg protein. The invention also relates to nucleic acids encoding said phytase as well as methods for the production o...
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WO/1997/040173A2 |
Polynucleotide constructs encoding growth factor independent catalytically active membrane targeted PI 3-kinase mutants useful for therapeutic and research purposes are described. In addition, a method for using the polynucleotide constr...
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WO/1997/028270A1 |
Methods for making lysophosphatidylcholine are provided, comprising hydrolysis of a mixture of phosphatidylcholine and an agent with phospholipase A2. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monog...
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WO/1997/018307A1 |
A protein comprising the human Fas Ligand protein (hFasL) or a truncated human Fas Ligand protein or a functionally equivalent variant thereof that retain the Fas receptor-binding and apoptosis-inducing properties of hFasL and, linked ei...
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WO/1997/017460A1 |
A process for producing phosphatidylserines having a side chain derived from a polybasic unsaturated fatty acid. A natural lecithin containing a fatty acid side chain derived from a polybasic unsaturated fatty acid is used as the feedsto...
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WO/1996/040969A1 |
2-Ketoaldonic acid is synthesized by aldolase condensation reaction involving pyruvate and an aldose acceptor in the presence of excess pyruvate. After the reaction is substantially complete, the excess pyruvate is removed from the react...
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