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WO/2023/246071A1 |
The present invention provides an mreC mutant and use thereof in L-valine fermentative production. The mreC mutant is a protein obtained by mutating proline at position 150 in the wild-type mreC amino acid sequence into leucine. The intr...
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WO/2023/250066A1 |
The present disclosure provides cell lysis buffers and method of use. Cell lysis buffers may comprise an aqueous solution comprising a buffering agent, a detergent, and cyanate or thiocyanate. The cell lysis buffers may be free or substa...
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WO/2023/246131A1 |
The present invention provides a double-core-shell loaded microbial material as well as a preparation method therefor and the use thereof. The double-core-shell loaded microbial material is used for mineralizing heavy metals in polluted ...
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WO/2023/247740A1 |
The present invention provides a method of producing amino acids by fermentation in a bioreactor, wherein the bioreactor comprises methanogenic microorganisms in a fermentation broth, the method comprising at least the step of feeding a ...
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WO/2023/246505A1 |
The present invention relates to a method for inhibiting biogenic hydrogen sulfide in an oil field. A synergistic inhibition system combination agent containing Bacillus licheniformis GW1 is added into an oil field system, wherein the Ba...
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WO/2023/248512A1 |
The present invention addresses the problem of providing a technology that makes it possible to remove nitrogen in wastewater with a wide range of salt concentrations. The present invention provides mixed microorganisms wherein: the mi...
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WO/2023/245933A1 |
Disclosed herein are a method for efficiently producing L-homophenylalanine and a strain for producing L-homophenylalanine. According to the present invention, a new pathway for synthesizing L-homophenylalanine via enzymatic cascade reac...
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WO/2023/246674A1 |
Provided is a Bifidobacterium bifidum strain ibiome001, which can significantly reduce the weight and white fat mass of high-fat feed-induced obese and diabetic mice, and improve the expression of lipolytic genes ATGL and HSL. The fastin...
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WO/2023/247741A1 |
The present invention provides a method of producing amino acids by fermentation in a bioreactor, wherein the bioreactor comprises methanogenic microorganisms in a fermentation broth, the method comprising at least the step of feeding a ...
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WO/2023/248690A1 |
The present disclosure provides an agent for inducing plant disease resistance, the agent being capable of effectively inducing resistance to disease in plants. An agent for inducing plant disease resistance according to the present disc...
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WO/2023/247577A1 |
The present invention relates to the use of human milk oligosaccharides (HMOs) for improving the regeneration and/or viability of Lactobacillus bacteria in acidic environments. HMOs were found to increase the number of viable Lactobacill...
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WO/2023/250308A1 |
The subject invention provides safe, environmentally-friendly compositions and efficient methods for defoaming or inhibiting foam production. More specifically, the subject invention provides compositions derived from microorganisms for ...
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WO/2023/245240A1 |
Provided herein is a method of promoting sexual maturity in a collection of aquatic animals comprising feeding the animals recombinant algae that express a gonad stimulating hormone that promotes sexual maturity. Further disclosed is met...
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WO/2023/250421A1 |
The present disclosure relates to use of probiotic compositions and/or histamine degrading enzymes for the control of histamine in a farm production animal, companion animal, aquaculture, or a human, to reduce or eliminate the incidence ...
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WO/2023/246507A1 |
Disclosed is a cell-free reaction system, comprising a DNA/RNA template and a cell extract, the cell extract being a gene-knockdown cell extract. Further disclosed are multiple cell-free reaction systems for analysis and detection, which...
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WO/2023/245971A1 |
Disclosed is a method for improving adhesion force of a recombinant mussel foot protein. According to the method, by means of bioinformatics and molecular dynamics simulation, solvent accessibility of protein molecule amino acid residues...
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WO/2023/248870A1 |
This endoribonuclease comprises the amino acid sequence of (a) or (b) below and hydrolyzes the phosphodiester bond between U and A in 5'-UACU-3' or 5'-UACG-3' included in RNA. (a) An amino acid sequence represented by SEQ ID NO: 1. (b) A...
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WO/2023/247578A1 |
The present invention relates to the use of human milk oligosaccharides (HMOs) for improving the regeneration and/or viability of Bifidobacteria in acidic environments. HMOs were found to increase the number of viable Bifidobacteria upon...
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WO/2023/250487A1 |
Provided herein are achromosomal dynamic active systems comprising a Type 1 pilus (T1P) and methods of making and using the same.
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WO/2023/249363A1 |
The present invention relates to a composition that substitutes for fetal bovine serum (FBS). More specifically, the composition includes an insect protein hydrolysate for use in cell cultures and when used for various animal-derived cel...
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WO/2023/250129A1 |
The present disclosure provides compositions and methods for producing high-purity squalene from a squalene source, for example from host cells, such as yeast cells that are capable of synthesizing squalene. Further provided herein are c...
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WO/2023/245191A2 |
A programmable cell-lysis system and related compositions and methods are described, which facilitate expression and harvest of recombinant proteins from host cells. The programmable cell-lysis system comprises a host cell comprising a p...
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WO/2023/242308A1 |
A process is provided for producing a biomass material which is stabilised against oxidation. In particular, the process comprises the steps of: treating the concentrated biomass material with an antioxidant; and adjusting the pH of the ...
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WO/2023/240936A1 |
Disclosed in the present invention are Lactobacillus reuteri for prolonging the lifespan, resisting aging and reducing fat, and a product thereof and the use thereof. The Lactobacillus reuteri is Lactobacillus reuteri A21041, which is ta...
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WO/2023/245018A2 |
The present invention provides engineered bacterial spores that comprise a cargo protein conjugated to a spore coat protein. Also provided are bacteria and methods for producing the spores and methods of using the spores to deliver a car...
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WO/2023/242195A1 |
The present invention relates to cannabichromenic acid synthase (CBCAS) variants that have increased enzymatic activity and thus allow efficient recombinant production of cannabichromenic acid (CBCA). The invention further relates to nuc...
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WO/2023/244843A1 |
The present disclosure relates to the methods and compositions for enhancing productivity or yield in fermentation. The methods include culturing host cells at a high pH to increase oxygen uptake as well as a higher yield and productivit...
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WO/2023/243495A1 |
Provided is a method capable of expressing and activating the function of a G-protein conjugated receptor (GPCR). A method for expressing a GPCR polypeptide comprises expressing, in a cell, a GPCR polypeptide comprising an amino acid seq...
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WO/2023/243924A1 |
The present invention relates to a novel Micrococcus terreus strain, a disrupted solution thereof, a culture medium, an extract of the culture medium, and a use thereof for improving skin condition. The strain has a skin condition-improv...
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WO/2023/240794A1 |
The present invention relates to recombinant Escherichia coli for producing L-homoserine and the use thereof. L-homoserine synthesis related genes in Escherichia coli are modified on a genome level by means of metabolic engineering; and ...
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WO/2023/244847A2 |
Disclosed herein are methods and compositions for manufacturing, processing and storing composite materials, containing bacterial cellulose and eukaryotic cells, e.g., fungal cells. The methods comprise a first culture, in which bacteria...
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WO/2023/243624A1 |
The present invention provides a plastic fluid composition comprising: (1) a microorganism; and (2) a polysaccharide or nanofibers made of the polysaccharide, wherein when the microorganism is a bacteria, the microorganism is contained...
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WO/2023/243709A1 |
Provided are a method and a living cell freezing system for freezing an unfrozen specimen comprising living cells in such a manner as to keep the cells alive. The method comprises: causing an unfrozen specimen to reach a frozen state by ...
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WO/2023/243727A1 |
The purpose of the present invention is to provide a preservative composition which is used in place of or in combination with a cell-penetrating substance such as DMSO that has been commonly used in a culture medium for cryopreservation...
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WO/2023/242273A1 |
The present invention relates to the animal-free production of casein proteins for human consumption by expression of such proteins in fungal cells. The invention relates to fungal cells modified for the production of caseins, and to met...
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WO/2023/240871A1 |
Provided are a glutamate decarboxylase mutant and the use in the production of γ-aminobutyric acid. Further provided are an improved recombinant Corynebacterium glutamicum and a biosensor capable of responding to γ-aminobutyric acid.
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WO/2023/241224A1 |
Disclosed in the present application are a method for biosynthesizing nootkatone and a carrier. The method comprises using recombinant bacteria, which is capable of expressing valentene synthase, cytochrome P450 oxidase, cytochrome P450 ...
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WO/2023/242307A1 |
A method is provided for isolating a nucleic acid rich product from an aqueous biomass material. After steps of heat-shock treatment and incubation, the aqueous biomass material is separated, to provide a first concentrated biomass mater...
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WO/2023/240607A1 |
Provided is a gene editing method for the genome of bacteria capable of producing bacterial cellulose. The method comprises the following steps: S1) determining a target gene or site to be modified in bacteria capable of producing cellul...
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WO/2023/241768A1 |
The invention relates to a method of processing a mycelium object (30) in the form of a mycelium fibril into a mycelium product (MYP), the mycelium object comprising hyphae cells, said hyphae cells having cell walls, the cell walls of sa...
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WO/2023/241767A1 |
The invention relates to a method and apparatus of processing a mycelium object (30) into a mycelium product (MYP) by using a processing fluid in supercritical conditions, the mycelium object comprising hyphae cells, said hyphae cells ha...
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WO/2023/243602A1 |
Provided is a cell patterning method and a cell patterning device which make it possible to control cell proliferation and to easily pattern the shape of a cell population. The cell patterning method comprises: a step for allowing cells ...
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WO/2023/240678A1 |
Disclosed are a polyketone compound with an anti-inflammatory activity, and a preparation method therefor and the use thereof. The method comprises: isolating Penicillium endophytic fungus (Penicillium sp.) HJT-A-10 from a root slice col...
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WO/2023/244964A1 |
A method for extracting a metal of interest from a mineral substrate comprising: 1) providing a mineral substrate containing a metal of interest, 2) contacting the mineral substrate with a leaching medium comprising a pH reducing microor...
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WO/2023/243335A1 |
A microorganism culturing device according to the present invention is provided with: a culturing tank that houses a liquid culture containing a microorganism; a spraying part provided in the culturing tank; and a gas releasing pipe for ...
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WO/2023/243097A1 |
Provided are a live cell freezing system and a method for freezing live cells that includes cooling an unfrozen sample that contains a freezing solution containing a cryoprotectant and live cells that are immersed in the freezing solutio...
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WO/2023/240679A1 |
The present invention relates to the technical field of medicines, and disclosed are a pair of polyketide compounds having anti-inflammatory activity, a preparation method therefor, and a use thereof. Specifically, endophytic fungus Alte...
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WO/2023/240910A1 |
Bacillus halotolerans BJ-3 and an application thereof, the Bacillus halotolerans BJ-3 having a preservation number CGMCC No. 24115. Said strain of Bacillus halotolerans exhibits bacterial inhibition activity with regard to phytopathogeni...
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WO/2023/238486A1 |
A bioreactor 10 has a housing space 101 that holds a liquid containing a specific alga. A vector potential coil of a vector potential coil device 1 is disposed in at least one of the housing space 101 and outside of the bioreactor 10. A ...
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WO/2023/239145A1 |
The present application relates to: a microorganism deposited under accession number KCCM12835P; a method for producing riboflavin using the microorganism; a composition for producing riboflavin, the composition comprising the microorgan...
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