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WO/2021/081136A1 |
A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wel...
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WO/2021/066645A1 |
A measuring system for automatically determining and/or monitoring the quality of a liquid or viscous foodstuff comprises a housing (2) with an interior space for a product container (4) for such a foodstuff, a lid (5) provided with a pr...
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WO/2021/067353A1 |
The technology described herein generally relates to microfluidic cartridges. The technology more particularly relates to a compressible pad applied to a microfluidic cartridge, wherein the microfluidic cartridge is configured to amplify...
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WO/2021/048545A1 |
The invention relates to new methods for synthesising polynucleotide molecules according to a predefined nucleotide sequence. The invention also relates to methods for the assembly of synthetic polynucleotides following synthesis, as wel...
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WO/2021/047879A1 |
The invention relates to a device (1) for the thermal treatment of samples, as well as a method for operating a device according to the invention. The device comprises: a base unit (2) having a receiving region (6) for receiving at least...
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WO/2021/050002A1 |
Thermal cycling apparatus for polymerase chain reaction (PCR) of nucleic acid is provided. Bath mediums (75) in a first bath (50) and a second bath (51) are maintainable at two different temperatures. A transfer means (85) allows the rea...
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WO/2021/037730A1 |
The present inventive concept relates to a system for monitoring a PCR-reaction in a microfluidic reactor. The system comprises: a first light source illuminating the microfluidic reactor through a first excitation light filter providing...
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WO/2021/025233A1 |
The present invention relates to a diagnostic cartridge for microfluidics and an on-site molecular diagnosis system including same, wherein an infuser, an extraction chamber, and an amplification chamber are arrayed vertically to minimiz...
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WO/2021/026261A1 |
A microfluidic passive plasma separation device is disclosed that provides rapid and efficient separation of optically clear plasma from whole blood. In various embodiments, the device comprises an engineered filter pad; a microfluidic c...
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WO/2021/023352A1 |
The present invention relates to a system for amplification of polynucleotides from a predefined number of single cells. The system comprise a device (or part) providing the predefined number of single cells, at a previously defined inle...
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WO/2021/018801A1 |
Systems for nucleic acid amplification testing are provided. The systems comprise a consumable amplification module and a reader module for receiving the amplification module. The amplification module comprises: a reactor vessel for cont...
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WO/2021/018807A1 |
A heater for thermocycling to carry out PCR amplification. The heater comprises: a thermal diffusion layer having a reaction surface for transferring heat to a reaction cell; a heater track support layer having a back surface for cooling...
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WO/2021/014305A1 |
The present invention refers to an integrated and automated device (1) for carrying out molecular and/or cellular biology laboratory procedures, characterized in that it comprises: - an apparatus for handling fluids (2) configured to all...
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WO/2021/011630A1 |
Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a mul...
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WO/2021/008679A1 |
The present disclosure relates to a sample transfer apparatus (100) for transferring a sample holder (200) into and out of a vacuum chamber (810), comprising: a holding device (110) including at least one cam (120) configured to cooperat...
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WO/2021/006956A1 |
Systems for probing superconducting circuits, including using a non-magnetic cryogenic heater, are disclosed. A system including a circuit board having a socket and a heater, mounted on the socket, is provided. The heater includes a resi...
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WO/2021/002602A1 |
The present invention relates to an all-in-one kit including a biological specimen pretreatment and molecular diagnosis module for detection of on-site pathogens, the all-in-one kit being characterized by comprising: a kit body of which ...
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WO/2020/225286A9 |
The invention relates to a method for extracting a target nucleic acid (22) from a sample liquid (500). The method comprises providing a heating device having a heating element (10) in contact with the sample liquid (500), wherein the he...
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WO/2021/002941A1 |
A system and method for automated cell lysis and purification processing including a tray having a series of open fluid wells. A first well is a process well for cell processing and additional wells are for buffer storage. A sonication c...
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WO/2021/001355A1 |
The invention relates to a microfluidic device (100) for processing and aliquoting a sample liquid (10). The microfluidic device (100) has a dividing chamber (115) for receiving a starting volume of the sample liquid (10). The dividing c...
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WO/2020/254691A1 |
The present disclosure relates to a microfabricated thermal platform. The platform is formed over a substrate, which may for example be a silicon wafer, and which may form part of the platform. The substrate is coated in a thermally-insu...
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WO/2020/257356A2 |
Described herein are devices, systems, fluidic devices, kits, and methods for detection of target nucleic acids.
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WO/2020/257297A1 |
The present disclosure provides devices, systems, methods for processing and/or analyzing a biological sample. An analytic device for processing and/or analyzing a biological sample may comprise a moving carriage. The analytic device may...
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WO/2020/247671A1 |
Systems for performing cellular analysis and related devices for conditioning environments adjacent chips in such systems. A device for conditioning an environment adjacent a chip in a system for performing cellular analysis, the device ...
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WO/2020/242261A1 |
The disclosure relates to a method for detecting a target nucleic acid in a sample using a nucleic acid reaction detection device comprising a plurality of reaction areas independent from each other. According to the disclosure, the meth...
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WO/2020/243047A1 |
The disclosure describes a heat delivery medium and composition for biomedical applications with controlled conversion of energy from an exogenous source to heat.
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WO/2020/242189A1 |
The present invention relates to a polymerase chain reaction (PCR) device which may comprise: a microfluidic chip having top and bottom surfaces patterned with metal; and a PCR processing unit including a first region, a second region po...
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WO/2020/237017A1 |
Methods using photothermal nanoparticles in rapid nucleic acid amplification and photothermal nanoparticles include forming a reaction mixture comprising a nucleic acid template, a polymerase enzyme, and a heating media. The heating medi...
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WO/2020/226552A1 |
A holding device (2) for a sample (1), having a sample surface (Ss) and a back surface (Bs) is described as well as a heating system comprising the holding device. The holding device (2) is configured for a heating system (100) and compr...
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WO/2020/223185A1 |
This disclosure relates to apparatus and methods for thermally cycling a sample. Particular embodiments comprise a first pivot arm configured to pivot around a first pivot axis; a second pivot arm configured to pivot around a second pivo...
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WO/2020/223257A1 |
In some embodiments, a stand-alone molecular diagnostic test device includes a detection circuit that includes a light emitting device and a light receiving device (e.g., a photodiode) that are arranged to produce an electronic signal as...
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WO/2020/223316A1 |
Variable temperature analytical assemblies are provided and/or methods for changing temperatures of a mass are provided. Low thermal conductance components and/or assemblies are also provided. Methods for thermally isolating a mass from ...
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WO/2020/222119A1 |
The device (1) for determining properties of hydrocarbon fluids and similar substances comprises a containing casing (2), thermoregulating means (11, 12) and a working unit (7) in which samples containing hydrocarbon fluids and similar s...
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WO/2020/223578A1 |
A microfluidic system for high throughput characterization of interactions between pairs of cells is provided. A first cell is loaded into a capture chamber and transferred to a culture chamber, and then a second cell is captured and tra...
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WO/2020/214274A1 |
A sealed container having gloves attached thereto is provided as part of a physical properties measuring system (PPMS). The PPMS includes a sealed pressurized portion that is pressurized with a gas to purge out air from inside the sealed...
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WO/2020/209638A1 |
The present invention relates to a system structure capable of detecting, in real time, nucleic acid extraction and amplification reactions and amplified products in an apparatus for implementing a polymerase chain reaction, the system s...
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WO/2020/210420A1 |
The present invention is directed towards a millimeter wave-based polymerase chain reaction cycler and methods of use thereof.
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WO/2020/197487A1 |
A real-time PCR chip (10) comprising: a main body (900), the main body comprising a chamber for performing PCR therein and an inlet (101) to allow placement of a test sample and appropriate reagents into the chamber; a bio-sensor formed ...
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WO/2020/190035A1 |
Provided a thermal cycler. In a case in which plurality of heat sinks participate in thermal control of a plurality of thermally independent sample holders for reliable nucleic acid reactions of the plurality of sample holder, a barrier ...
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WO/2020/187503A1 |
The invention relates to an apparatus for the thermal treatment of samples contained in sample containers (9), said apparatus comprising: a sample block (4) with a receiving region for the sample containers (9); a first temperature-contr...
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WO/2020/190454A1 |
Disclosed herein include systems, apparatuses, devices, and methods for introducing one or more components into a fluid. A first fluid and a second fluid can be co-injected into a fluidic channel of a flow cell. In some embodiments, the ...
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WO/2020/191193A1 |
The present disclosure provides devices, systems, methods for processing and/or analyzing a biological sample. An analytic device for processing and/or analyzing one or more biological samples may be electronically and/or physically conf...
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WO/2020/184844A2 |
The present invention relates to an independently temperature controllable block for PCR. More specifically, the purpose of the present invention is to provide a temperature circulation apparatus which is for PCR and has a plurality of i...
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WO/2020/180858A1 |
This invention relates generally to devices, systems, and methods for avoiding bubble formation in a fluidic chamber during filling of the fluidic chamber with a liquid. A first and second piece are operatively coupled to form the fluidi...
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WO/2020/172444A1 |
A scanning apparatus that can include (a) a scan actuator including a linear actuator and a mount for a removeable vessel, wherein the mount has a mechanical fastener that is configured to engage a complementary mechanical fastener on th...
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WO/2020/155607A1 |
A PCR base (2) and a PCR device, the PCR base (2) comprising a metal block body, the metal block body having disposed thereon multiple hole slots used to accommodate tube bodies of a PCR plate (1); in a room temperature environment of 22...
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WO/2020/157646A1 |
A sample vessel assembly to carry out a sorption analysis in a container provided with a cooling liquid. The sample vessel assembly includes a sample vessel configured to be suspended within the container. The sample vessel has a sample ...
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WO/2020/156879A1 |
The invention relates to a method for controlling the temperature of reaction mixtures (2) in an agitation operation, wherein at least two reaction mixtures (2) in at least two reaction vessels (1) are individually temperature-controlled...
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WO/2020/160335A1 |
A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first...
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WO/2020/154642A1 |
A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of o...
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