MICROORGANISM THAT SUPPRESSES AGGREGATION OF α-SYNUCLEIN AND PRODUCTION METHOD THEREFOR

Title:

MICROORGANISM THAT SUPPRESSES AGGREGATION OF α-SYNUCLEIN AND PRODUCTION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2024/096124

Kind Code:

A1

Abstract:

The present disclosure provides a microorganism that inhibits oligomer formation of sgA. More specifically, the present disclosure provides a microorganism wherein at least one gene among the curli pili operon gene group, sigma factor gene group, catabolite repressor gene group, and two component regulatory gene group in the microorganism is modified, and this modification suppresses aggregation of α-synuclein in a host in comparison to a microorganism in which said gene is unmodified.

More Like This:

WO/2015/104994	RECOMBINANT ANAEROBIC GRAM-POSITIVE BACTERIA
JP5827303	Recombinant N-glycosylation protein derived from prokaryotic cells
JPH0653070	[Title of Invention] Method for Producing Recombinant Plasminogen Activator Protein

Inventors:

MIYAZAKI SHOKO (JP)
TAMIYA TAIGA (JP)
OKUMURA RYO (JP)

Application Number:

PCT/JP2023/039719

Publication Date:

May 10, 2024

Filing Date:

November 02, 2023

Export Citation:

Click for automatic bibliography generation Help

Assignee:

BIO PALETTE CO LTD (JP)

International Classes:

C12N1/21; A61K35/74; A61P25/28; A61P43/00; C12N15/09

Attorney, Agent or Firm:

KAMADA, Mitsunori et al. (Meiji Yasuda Seimei Osaka Midosuji Bldg. 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: GENETICALLY MODIFIED MICROORGANISM AND METHOD FOR PRODUCING SAME

Next Patent: METHOD FOR DESIGNING OR PRODUCING BACTERIAL PREPARATION CONTAINING MICROORGANISM HAVING DESIRED PHAR...