Title:
METHOD FOR DESIGNING OR PRODUCING BACTERIAL PREPARATION CONTAINING MICROORGANISM HAVING DESIRED PHARMACOLOGICAL EFFICACY
Document Type and Number:
WIPO Patent Application WO/2024/096125
Kind Code:
A1
Abstract:
The present disclosure provides a technique for efficiently designing or producing a bacterial preparation utilizing a bacterium capable of exhibiting a desired trait or a desired efficacy. More specifically, the present disclosure provides a method for designing or producing a bacterial preparation containing a microorganism having a desired pharmacological efficacy in a subject, the method comprising: a step of selecting or screening for at least one gene associated with the pharmacological efficacy; a step of modifying the gene; a step of selecting a microorganism in which the expression level of the gene is altered and/or a microorganism in which the function of a protein produced by the gene is modified; a step of confirming whether or not the selected microorganism has the desired pharmacological efficacy and then selecting a microorganism having the pharmacological efficacy; and an optional step of producing a mass containing the microorganism having the desired pharmacological efficacy if necessary.
Inventors:
OKUMURA RYO (JP)
IWATA KIYOKAZU (JP)
KURAMOTO KAHO (JP)
MIYAZAKI SHOKO (JP)
KIRA SHINTARO (JP)
MITSUNOBU HITOSHI (JP)
NISHIDA NAMBU YUMIKO (JP)
IWATA KIYOKAZU (JP)
KURAMOTO KAHO (JP)
MIYAZAKI SHOKO (JP)
KIRA SHINTARO (JP)
MITSUNOBU HITOSHI (JP)
NISHIDA NAMBU YUMIKO (JP)
Application Number:
PCT/JP2023/039720
Publication Date:
May 10, 2024
Filing Date:
November 02, 2023
Export Citation:
Assignee:
BIO PALETTE CO LTD (JP)
International Classes:
C12N15/09; C12N1/20; C12N1/21; C12Q1/04
Attorney, Agent or Firm:
KAMADA, Mitsunori et al. (JP)
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