Title:
METHOD FOR IMPROVING THE QUALITY OF POLYGONUM CAPITATUM EXTRACT AND QUALITY OF RELINQING GRANULES
Document Type and Number:
WIPO Patent Application WO/2024/077490
Kind Code:
A1
Abstract:
A method for improving the quality of a Polygonum capitatum extract and quality of Relinqing granules, said method comprising the following steps: (1) adding ethanol to a dry product of the overground part of a Polygonum capitatum medicinal material to perform reflux extraction, performing filtration, concentrating a filtrate, and drying same to obtain an alcohol extract; (2) adding water to filter residues obtained in step (1), decocting and extracting same, performing filtration, concentrating a filtrate, and drying same to obtain an aqueous extract; (3) mixing the alcohol extract and the aqueous extract, and carrying out spray drying to remove water to obtain a Polygonum capitatum extract; and (4) mixing the Polygonum capitatum extract with a proper amount of starch, performing granulation with water, drying same to obtain a Relinqing granular preparation, and carrying out thin-layer chromatography and fingerprint tests on the Polygonum capitatum extract and/or the Relinqing granules.
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Inventors:
TANG JINGWEN (CN)
LU LIPING (CN)
PAN MEI (CN)
LIANG BIN (CN)
ZHANG LIYAN (CN)
LU LIPING (CN)
PAN MEI (CN)
LIANG BIN (CN)
ZHANG LIYAN (CN)
Application Number:
PCT/CN2022/124674
Publication Date:
April 18, 2024
Filing Date:
October 11, 2022
Export Citation:
Assignee:
GUIZHOU WEIMEN PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K36/704; A61P13/00; G01N30/90; G01N30/95
Foreign References:
| CN103550311A | 2014-02-05 | |||
| CN102608248A | 2012-07-25 | |||
| CN102526219A | 2012-07-04 |
Other References:
XIE YU: "Characteristic Spectrum Establishment of Polygonum capitatumand Relinqing Granules by TLC", GUIZHOU AGRICULTURAL SCIENCES, vol. 42, no. 7, 15 July 2014 (2014-07-15), pages 31 - 35, XP093158356
QING JUAN: " Study on Thin Layer Chromatography Fingerprint of Polygonum Capitatum Medicinal Material", STUDIES OF TRACE ELEMENTS AND HEALTH, vol. 31, no. 2, 13 January 2014 (2014-01-13), pages 62 - 63, XP093158360
QING JUAN: " Study on Thin Layer Chromatography Fingerprint of Polygonum Capitatum Medicinal Material", STUDIES OF TRACE ELEMENTS AND HEALTH, vol. 31, no. 2, 13 January 2014 (2014-01-13), pages 62 - 63, XP093158360
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