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JPH0613534B2 |
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JPH0641186A |
PURPOSE: To provide a hydrophobic vitamin b12 derivative absorbable by diffusion. CONSTITUTION: 5-20C Alkyl group is linked to the upper ligand of vitamin B12 to give a hydrophobic vitamin b12 derivative.
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JPH06500797A |
There are provided purine-base modified guanosine analogues, for example 2'-deoxy, and then ribonucleosides for incorporating into triplex-forming oligonucleotides. Also provided are triplex-forming oligonucleotides for binding into stra...
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JPH069677A |
PURPOSE: To obtain a new deriv. useful as an antineoplastic drug. CONSTITUTION: This new deriv. is a diosmin heptakis (hydrogensulfate) aluminum complex expressed by the formula (R is SO3(Al2(OH)5)). The compd. of the formula is obtd. by...
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JPH06500107A |
Novel oligonucleotides formed from alpha -D-arabinofuranosyl nucleoside monomers, including oligonucleotides in which one or more of the monomer units is functionalized, are disclosed herein, as well as functionalized monomeric alpha -D-...
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JPH06500075A |
Methods for achieving therapeutic treatment of diseases and for regulating gene expression in biological experimental systems via modification or removal of the 5' Cap structure of targeted ribonucleic acids are disclosed. Modification o...
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JPH05345794A |
PURPOSE: To industrially profitably obtain the subject compounds used for treating cancer-tumor diseases, etc. by allowing specific anthracyclinone compounds to react with a specific functionalized hydrocarbon biomonomer in an waterless ...
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JPH0586190B2 |
The invention relates to a process for the conversion of corrinoids produced by microorganisms into cyanocorrinoids by reaction with cyanides. According to the invention a fermentation broth obtained by disruption of microorganism cells ...
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JPH05508152A |
2'3'-dideoxy-4'-thioribonucleosides useful as antiviral agents in the treatment and prevention of AIDS are disclosed. In accordance with one aspect of the invention there are provided compounds of the formula where X=H, N3 or F, and B is...
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JPH05507619A |
(57) [Summary] Since this publication is application data before electronic filing, summary data is not recorded.
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JPH0579385B2 |
Disclosed is a centrifugal microconcentrator and methods for using the microconcentrator to concentrate macromolecules from a solution without filtering to dryness and to centrifugally recover a maximal amount of concentrated macromolecu...
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JPH05507518A |
Fluorescent dyes which are free of aggregation and serum binding are provided. These dyes are suitable for applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy.
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JPH0576927B2 |
Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents, wherein the sucralfate is present in the form of a gel having self-suspending properties and is suspended in an aqueous carbohydrate solu...
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JPH05507265A |
A novel class of pharmaceutically active boronated nucleosides are provided. The nucleosides are boronated at a ring nitrogen of the purine or pyrimidine or analogues thereof. Also provided are phosphate esters of these nucleosides and o...
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JPH0572919B2 |
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JPH0572920B2 |
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JPH05255378A |
PURPOSE: To obtain the subject compounds that are useful as antileukemic agents by conducting silanization and acylation of chloroadenosine in order, by reacting the obtained product with an organotin hydride and a radical initiator, and...
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JPH0569839B2 |
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JPH0567156B2 |
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JPH0565108B2 |
A method for the fluorescent labelling of a sugar or a sugar chain by labelling the reducing end of the sugar or sugar chain with a fluorescent substance, wherein the improvement comprises first forming a Schiff base by reacting the surg...
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JPH0561204B2 |
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JPH0560475B2 |
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JPH05211872A |
PURPOSE: To provide both the use of an energy transfer system for measuring the distance within a molecule or between different molecules, especially in a DNA or an RNA sequence or between the different DNA or RNA sequences and a method ...
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JPH0555518B2 |
The invention relates to a novel diosmin derivative and to the preparation of this diosmin octakis(hydrogen sulphate)/aluminium complex by reacting diosmin with a sulphating agent such as the sulphur dioxide/pyridine complex, the sulphur...
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JPH0553378B2 |
Vitamin B12 in liquid samples, such as human serum or human plasma, is assayed by a competitive binding technique using intrinsic factor and certain labelled vitamin B12 derivatives. The labelled derivatives are formed from the (d)-monoc...
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JPH05505178A |
Disclosed are oligonucleoside boranophosphates, or salts thereof, comprising a chain of natural or modified ribonucleotides or deoxyribonucleotides, containing at least one boronated internucleotide phospodiester linkage of the formula: ...
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JPH0546324B2 |
A process for preparing a platinum green complex which comprises reacting a compound represented by the following general formula (I) with a compound selected from among uridine, thymidine, uracil, thymine, 2 min -deoxyuridine, uridine-5...
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JPH05170785A |
PURPOSE: To provide a simple derivation method of an oligosaccharide useful as a substrate for an α-amylase. CONSTITUTION: The direct silylation reaction of the terminal non-reduced glucose unit of the oligosaccharide which is an oligos...
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JPH0542438B2 |
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.
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JPH05117294A |
PURPOSE: To provide new hydrophobic cobalamin derivatives improved in asymmetry-recognizing functions and useful for resolving a racemic compound as an asymmetric catalyst. CONSTITUTION: Compounds of formula I {R, together with R' forms ...
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JPH0578381A |
PURPOSE: To obtain the subject compound in high yield by condensing a sialic acid thioglycoside with a saccharide derivative in the presence of N- iodosuccinimide and trifluoromethanesulfonic acid. CONSTITUTION: A sialic acid thioglycosi...
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JPH059439B2 |
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JPH055838B2 |
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JPH059127A |
PURPOSE: To provide an organism, especially a plant, containing a saccharide germanium complex absorbed therein. CONSTITUTION: A saccharide germanium complex-containing plant is prepared by allowing a plant to absorb a saccharide germani...
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JPH04506509A |
PCT No. PCT/DK89/00192 Sec. 371 Date Apr. 11, 1991 Sec. 102(e) Date Apr. 11, 1991 PCT Filed Aug. 11, 1989 PCT Pub. No. WO90/01488 PCT Pub. Date Feb. 22, 1990.A method for treating infections caused by galabiose-binding bacteria using gal...
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JPH0463860B2 |
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JPH04178396A |
NEW MATERIAL:Compounds of formula I [R is cycloalkyl; R1 is H or lower alkylcarbonyl; X is halogen or group having structure of formula II formed by combination of two X; Y is Cl, OH or formula III (R2 is H, lower alkyl or lower alkylami...
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JPH04502754A |
A ligated technetium (III/II) complex is useful as a brain perfusion imaging agent. The complex has a technetium (III/II) center surrounded by six ligating moieties. The complex preferably has a reduction potential Tc(III) to Tc(II) whic...
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JPH04108796A |
PURPOSE: To obtain the subject complex useful as a medical drug having an antitumor activity by a ready method in high yield by reacting a specific compound with uridine, etc., in the presence of a silver salt and an oxidizing agent. CON...
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JPH04501427A |
A specific inhibitor product ofr retrovirus reverse transcriptase consists of an organic thio-compound with at least one S-Au link. Said compound may be a thio-glucose, such as 1-$g(b)-D-aurothioglucose, and 2,3,4,6-tetra-O-acetyl-1-thio...
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JPH0454193A |
PURPOSE: To obtain the subject compound useful as a remedy for AIDS or its raw material by condensing a 5-substituted pyrimidine derivative to a 2- organothio-2,3-dideoxy-pentofuranose derivative in the presence of a Lewis acid and subje...
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JPH0375559B2 |
Compounds having the structure: wherein B represents a purine, 7-deazapurine, or pyrimidine moiety covalently bonded to the C<1>-position of the sugar moiety, provided that when B is purine or 7-deazapurine, it is attached at the N<9>-po...
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JPH0375482B2 |
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JPH0375483B2 |
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JPH0374240B2 |
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JPH0374238B2 |
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JPH03261798A |
NEW MATERIAL: A compound of formula I (B is a purine, 7-deazapurine, or pyrimidine moiety covalently bonded to the C1'-position of the sugar moiety, provided that when B is purine or 7-deazapurine, it is attached at the N9-position and w...
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JPH0366318B2 |
Platinum complexes of the general formula:- wherein X is a halogen atom and G is a glucuronic acid residue of the formula: the configuration of the diaminecyclohexane being selected from cis-, trans-1 - and trans-d- have been found to ex...
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JPH03228698A |
PURPOSE: To enable the simple sequencing of an oligosaccharide by placing an identifying label on a residue of the reducing terminal, dividing the resultant oligosaccharide into a plurality of separate portions of known integer amounts a...
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JPH03198798A |
PURPOSE: To determine a sequence of a DNA nucleoside base by identifying the position of the nucleoside base by recording the differences of electrical potentials measured along a passage of a scanning probe at preselected increment. CON...
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