Heterocyclic Compounds

Matches 201 - 250 out of 436	< 1 2 3 4 5 6 7 8 9 >

Document	Document Title
JP2024515215A	Antibacterial and anticancer agents Formula (I) useful as antineoplastic and antibacterial agents: [Formula 1] and compositions and methods of using the antineoplastic and antimicrobial compounds.
JP2024514316A	Novel methods for synthesizing enantiopure (S)-methadone, (R)-methadone, racemic (R,S)-methadone, and related analogue substances Enantiopure (S)-methadone, (R)-methadone, (R,S) with preservation of stereochemical configuration starting from optically active or racemic N-substituted cyclic sulfamidates or N-substituted aziridines -Methods for the synthesis of metha...
JP7449913B2	Method of making oxathiazine-like compounds Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes of treating patients suffering from cancers, bacterial infectio...
JP7339677B2	Fluorosulfonyl-containing compounds, intermediates, methods of preparation and uses thereof Disclosed in the present invention were a fluorosulfonyl-containing compound, an intermediate thereof, a preparation method therefor and use thereof. The fluorosulfonyl-containing compound disclosed in the present invention comprises a c...
JP2023093679A	ACESULFAME POTASSIUM COMPOSITION AND MANUFACTURING METHOD THEREOF To provide a composition and a method for producing high-purity acesulfame potassium.A method for producing high-purity acesulfame potassium comprising: forming a cyclic sulfur trioxide adduct; hydrolyzing the cyclic sulfur trioxide addu...
JP2023093678A	ACESULFAME POTASSIUM COMPOSITION AND MANUFACTURING METHOD THEREOF To provide a composition and a method for producing high-purity acesulfame potassium.A manufacturing method of an acesulfame potassium composition comprises: preparing a crude acesulfame potassium composition comprising acesulfame potass...
JP7270670B2	Acesulfame potassium composition and method for producing the same Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame potassium composition comprising acesulfame potassium and acetoacetamide, concentrat...
JP7270671B2	Acesulfame potassium composition and method for producing the same Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of forming a cyclic sulfur trioxide adduct; hydrolyzing the cyclic sulfur trioxide adduct to form an acesulfame-H co...
JP2023052166A	COMPOUND, COMPOSITION, AND, METHOD To provide a method of treating diseases.The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or pharmaceutically acceptable salts thereof, stereoisomers, mixtures of stereoisomers, or prodrugs thereof,...
JP2023502791A	Macrocyclic pantetheine derivatives and uses thereof The present disclosure provides compounds of formula (I) or (II): [Chemical 1] and pharmaceutically acceptable salts or solvates thereof. The disclosure also relates to pharmaceutical compositions comprising said compounds, and therapeut...
JP7169977B2	Acesulfame potassium composition and method for producing the same Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of forming a cyclic sulfur trioxide adduct; hydrolyzing the cyclic sulfur trioxide adduct to form an acesulfame-H co...
JP7111796B2	Acesulfame potassium composition and method for producing the same Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent...
JP7108741B2	Acesulfame potassium composition and its production method A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a solvent and having an initial temperature, cooling the cyclizing agent compositi...
JP7043096B2	Manufacture, raw materials, products and use of photocrosslinkable hydrogel materials This invention provides preparations, compositions, products, and applications of photo-crosslinked hydrogels. Component A - a photosensitive polymer derivative, component B - the photoinitiator, and auxiliary component C - other biocomp...
JP2022517466A	Carbon monoxide prodrug for the treatment of medical disorders The present invention provides novel compounds and compositions thereof that release carbon monoxide for the treatment of carbon monoxide-reactive medical disorders, such as inflammation, pain, and dermatological disorders. [Selection di...
JP7030093B2	How to make an oxathiadin-like compound Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes of treating patients suffering from cancers, bacterial infectio...
JP2022501411A	Processes and Intermediates for Preparing Specific Nematode Sulfonamides The present invention provides a method for preparing a compound of formula C, formula D, or formula F.
JP2021531303A	Elagolix Sodium Compositions and Methods The present invention relates to a composition of sodium ellagolix, as well as a method for preparing the composition and an intermediate for the preparation thereof.
JP6914201B2	Cyclic sulfamoylarylamide derivatives and their use as pharmaceuticals for the treatment of hepatitis B Inhibitors of HBV replication of Formula (I-A)including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Rato Rd, and R1to R8have the meaning as defined herein.The present invention also relates to processe...
JP6913692B2	How to make an oxathiazine-like compound Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes for efficient and safe manufacture of compounds useful for maki...
JP6912582B2	Acesulfame potassium composition and its production method A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a solvent and having an initial temperature, cooling the cyclizing agent compositi...
JP6912581B2	Acesulfame potassium composition and its production method Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame potassium composition comprising acesulfame potassium and acetoacetamide, concentrat...
JP6818896B2	Acesulfame potassium composition and its production method Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent...
JP2020530446A	Compounds, compositions, and methods The present disclosure generally describes eukaryotic initiation factor 2B modulators, or pharmaceutically acceptable salts thereof, stereoisomers, mixtures of stereoisomers, or prodrugs, and their manufacture and use. Regarding the meth...
JP6746605B2	How to make an oxathiazine-like compound Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes of treating patients suffering from cancers, bacterial infectio...
JP6630671B2	Nrf2 regulator The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.
JP6577951B2	New CYP-eicosanoid derivative The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention f...
JP6281952B2	HIV replication inhibitor The present invention provides a novel compound having an antiviral activity, in particular, an HIV replication inhibiting activity, as well as a pharmaceutical composition, in particular, an anti-HIV agent. wherein ring A is substituted...
JP6262228B2	The Arylsultam derivative as a RORc modulator Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are as defined herein. Also disclosed are methods of makin...
JP6111276B2	The macro ring compound by which conformation restrictions were carried out and by which total synthesis was carried out The conformationally restricted, spatially defined macrocyclic ring system of formula (I) is constituted by three distinct molecular parts: Template A, conformation Modulator B and Bridge C. Macrocycles described by this ring system I ar...
JP6013403B2	The method, the compound, constituent, and medium for sending 3-amino 1-propanesulfonic acid The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1 -propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, ...
JP5991766B2	A Epoxy eicosatrienoic acid similar object and a manufacturing method for the same Compounds and compositions comprising epoxyeicosatrienoic acid (EET) analogs that act as EET agonists and are useful as medications in the treatment of drug-induced nephrotoxicity, hypertension and other related conditions. Methods of ma...
JP5892612B2	A novel MEK inhibitor useful in the treatment of disease The invention pertains to compound of Formula (I) wherein X, Y, Z, R1, R2, R3, R4, A and A′ are as described hereinabove. Formula (I) and (II) compounds can be used in pharmaceutical compositions, useful for the treatment of diseases.
JP2015145401A	INHIBITORS OF HISTONE DEACETYLASE To provide compounds for medicament to inhibit histone deacetylase.This invention provides a compound such as phenyl hydroxamic acid substituted with a group comprising, for example, oxazepine, diazepine, thiazepine skeletons, pyrimidine...
JP5638250B2	Antistatic agent and antistatic composition composed of unsaturated quaternary ammonium salt compound
JP2014521592A	Murder 虫性 diaryl hetero ring derivative To provide pesticidal allylAryl heterocycle derivatives that are useful as a pesticidal compound. Pesticidal allylAryl heterocycle derivatives that are expressed by the Formula (I), and pesticides and an agent for controlling animal para...
JP2014516343A	Compounds for use in imaging, diagnosis and / or treatment of diseases of the central nervous system This invention relates to novel compounds suitable for labelling by 18F and the corresponding 18F labelled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds,...
JP5519862B2	An ionic liquid, an electrolyte for a lithium secondary battery containing the ionic liquid, and a lithium secondary battery including the electrolyte. The object of the present invention is to provide an ionic liquid having a chiral center in the structure of a cation contained therein, a lithium secondary battery electrolyte includes the ionic liquid, and a lithium secondary battery i...
JP5410677B2	Method for producing optically active aminopentane derivative, intermediate and method for producing the intermediate There are provided a process for preparing an optically active aminopentane derivative that is promising as a psychotropic agent, an antidepressant agent, an antiparkinsonian agent, an anti-Alzheimer's agent, an apoptosis inhibitor, or t...
JP2013537216A	Dihydrobenzoxatiazepine derivatives, their preparation, pharmaceutical compositions and use as AMPA receptor modulators Phenoxy-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepine-dioxide compounds (I) and their enantiomers and diastereoisomers, and addition salts with an acid or a base, are new. Phenoxy-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepine-dioxide compoun...
JP5219323B2	Antitumor ectinasaidin derivative This invention relates to compounds of the formula: ##STR00001## wherein: the substituent groups defined by R.sub.1, R.sub.2 are each independently selected of H, C(.dbd.O)R', C.sub.1 C.sub.18 alkyl, C.sub.2 C.sub.18 alkenyl, C.sub.2 C.s...
JP2013104031A	ELECTRICALLY CONDUCTIVE COMPOSITION AND APPLICATION OF THE SAME To provide an electrically conductive composition which becomes a film having excellent electrical conductivity and contains an electrically conductive polymer having excellent thermal stability, and to further provide an electrically co...
JP2013512893A	How to prepare deferasirox and polymorphs of deferasirox The present invention relates to processes for the preparation of deferasirox, an oral iron chelator developed to treat iron overload due to e.g. multiple blood transfusions. The present invention further provides novel deferasirox pseud...
JP2012232910A	PESTICIDAL ALLYL HETEROCYCLYL DERIVATIVE To provide pesticidal allyl heterocycle derivatives that are useful as a pesticidal compound.This invention relates to: the pesticidal allyl heterocycle derivatives are expressed by the Formula (I); and pesticides and an agent for contro...
JP5063860B2	Compounds with antiparasitic activity and drugs containing them Diamidine derivatives of formula (I) and their salts are new. Amidine derivatives of formula (I) and their salts are new. [Image] X : a group of formula (ii) or R 4; Z : -(CH 2) m-; m : 8 - 21; n : 0 or 1; Y : R 3 or a group of formula (...
JP5008812B2	Antitumor analog of ET-743 Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from...
JP2012512141A	4-Amino-1,2,3-benzoxathiazine derivative as a pesticide 4-Amino-1,2,3-benzoxathiazine compounds (I) and their salts, are new. 4-Amino-1,2,3-benzoxathiazine compounds of formula (I) and their salts are new. R1-R4 : H, halo, carbamoyl, thiocarbamoyl, nitro, cyano, hydroxy, SF 5 , 1-6C-alkyl, 2-...
JPWO2010044371A1	Insulin secretagogue Sweet receptor agonists such as Acesulfarm K, sucralose, saccharin or glycyrrhizin are used as active ingredients of insulin secretagogues. In addition, a test compound is added to cells expressing a sweet taste receptor, the sweet taste...
JP4854853B2	Transfection drug Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having general structure (A):
JP4818114B2	Cyclohexyl sulfones as γ-secretase inhibitors Compounds of formula I: inhibit gamma-secretase and hence find use in treatment or prevention of Alzheimer's disease.

Matches 201 - 250 out of 436	< 1 2 3 4 5 6 7 8 9 >