Heterocyclic Compounds

Matches 451 - 500 out of 9,623	< 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 >

Document	Document Title
WO/2017/192931A1	SUBSTITUTED IMDAZO[1,2-α]PYRIDINES, SUBSTITUTED IMIDAZO[1,2-α]PYRAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS The invention provides substituted imidazo[1,2-α]pyridine compounds, substituted imidazo[1,2-α]pyrazine compounds, related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compos...
WO/2017/186624A1	PROCESS FOR THE PREPARATION OF HERBICIDAL PYRIDINYLIMIDAZOLONE COMPOUNDS The present invention relates to a process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification.
WO/2017/188485A1	COMPOUND Provided is a compound represented by formula (A-V), wherein Y represents a p-valent anion; R1A to R8A each independently represent a hydrogen atom or an alkyl group having 1-10 carbon atoms; R9A and R10A each independently represent a h...
WO/2017/184624A1	COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY In one aspect, compounds of Formulae (I) and (II), or pharmaceutically acceptable salts thereof, are featured; Formula (I), Formula (II) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formulae (I) and (II) ...
WO/2017/183625A1	ORGANIC ELECTROLUMINESCENCE ELEMENT [Problem] To provide an organic electroluminescence element comprising, in order to improve the element characteristics of the organic EL element, in particular, so as to absorb 400-410 nm wavelength sunlight and not have effects on an i...
WO/2017/182853A1	AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID The present invention relates to an improved process for the preparation of Linezolid. More specifically, the present invention relates to an improved process for preparing(S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo- 5-oxazolidiny...
WO/2017/179883A1	COMPOUND, AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME The present specification relates to a compound expressed by the first chemical formula, and to an organic electronic element comprising same.
WO/2017/175986A1	ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound of the present disclosure provides an organic electroluminesce...
WO/2017/170952A1	TETRADENTATE LIGAND, AND PRODUCTION METHOD THEREFOR, SYNTHETIC INTERMEDIATE THEREOF, AND TRANSITION METAL COMPLEX THEREOF The present invention relates to: a novel compound that is useful as a ligand in a variety of catalytic organic synthetic reactions; a method for easily and efficiently producing said novel compound; a synthetic intermediate of said nove...
WO/2017/165256A1	ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS The present disclosure relates to compounds of formula (I) that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly ...
WO/2017/160922A1	ANALGESIC COMPOUNDS Disclosed herein are compounds of Formula (I), methods of synthesizing compounds of Formula (I), and methods of using compounds of Formula (I) as an analgesic.
WO/2017/157932A1	METHOD OF PREPARING SUBSTITUTED BICYCLO[1 1 1]PENTANES The invention relates to a new and efficient process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or ...
WO/2017/153952A1	5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. ...
WO/2017/147646A1	DUAL EMISSION FLUORESCENT COMPOUNDS The invention relates to a dual emission fluorescent compound comprising a chromophore suitable for exhibiting an emission at a first wavelength from an excited state; wherein the compound further comprises one or more groups suitable fo...
WO/2017/147893A1	POSACONAZOLE, COMPOSITION, INTERMEDIATE, PREPARATION METHOD THEREFOR, AND USES THEREOF The present invention relates to a compound represented by formula (III), R being selected from C1-C4 alkyls, substituted or unsubstituted phenyl or substituted or unsubstituted benzyl, and being preferably selected from isopropyl; and t...
WO/2017/148226A1	FLUOROBENZOXAZOLE COMPOUND AND USE THEREOF Disclosed are a fluorobenzoxazole compound of the structure as shown in formula I and the use thereof, wherein the compound has an excellent inhibiting and killing effect towards pest mites and mite ova, can be used as an acaricide for p...
WO/2017/137744A1	HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also...
WO/2017/127627A1	COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF The present invention relates to novel compounds that cross the blood-brain barrier and are effective inhibitors of neurological pathogens such as trypanosomes. The invention further relates to the use of these compounds for treating dis...
WO/2017/115780A1	OINTMENT An ointment is provided. The ointment stably comprises an oxazole compound that has specific inhibitory activity against PDE4 and that is represented by the following formula (11). The ointment can be efficiently absorbed into the skin.
WO/2017/108282A1	BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY A compound of formula (Ia) or (Ib) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of a histone deacetylase, and as such is useful in terepy, e.g. in the treatment of autoimmune disorders, mental disorders, ne...
WO/2017/099237A1	AMINOAZOLE DERIVATIVE A compound represented by formula (I) and having a property of modulating the activity of an androgen receptor, or a pharmaceutically acceptable salt of the compound. X represents S or O; Z represents (Ra)n-A-(CR13R14)0-1-(CR11R12)0-1-; ...
WO/2017/089389A1	TRYPANOSOMES INHIBITORS The invention relates to a compound of formula (I) wherein R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used in the treatment of Human African TRypanosomiasis.
WO/2017/087777A1	HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders...
WO/2017/083719A1	TRANSITION METAL FREE METHODS OF SYNTHESIS OF BIARYL COMPOUNDS The present disclosure provides methods of preparing biaryl compounds which do not require transition metal catalysts. In yet another aspect, the present disclosure provides pharmaceutical compositions comprising compounds as described h...
WO/2017/083809A1	TARGETING OXAZOLE STRUCTURES FOR THERAPY AGAINST INFLAMMATORY DISEASES Described herein are novel compositions, targeted therapeutic methods, and assays for neutralizing and/or inhibiting the activity of "oxazole-containing (OxC) compounds," to prevent or delay the onset of epithelial barrier dysfunction an...
WO/2017/075694A1	ANTIBIOTIC COMPOUNDS, PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS AND USES THEREFOR The present invention relates to compounds of formula (I) wherein G1 to G8 are as defined herein. The compounds are PK inhibitors and as such represent a new approach to treating pathogenic infections, including multidrug resistant patho...
WO/2017/076293A1	METHOD FOR PREPARING OXAZOLIDINONE INTERMEDIATE The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a "one-pot" reaction on a compound I, a compound J or a compound L wit...
WO/2017/078927A1	ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING Novel compounds having a formula (I), embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a s...
WO/2017/078403A1	A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME The present disclosure relates to a plurality of host materials and an organic electroluminescent device comprising the same. By using a specific combination of a plurality of host compounds, it is possible to provide the organic electro...
WO/2017/076982A1	MICROBIOCIDAL ANILIDE DERIVATIVES Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, and especially fungicides.
WO/2017/074053A1	COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME The present application relates to a compound in chemical formula (1) and an organic light-emitting device comprising same.
WO/2017/074052A1	ORGANIC LIGHT-EMITTING DEVICE The present application relates to an organic light-emitting device.
WO/2017/070024A1	OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AS ANTIBACTERIAL AGENTS The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at leas...
WO/2017/066964A1	OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AS ANTIBACTERIAL AGENTS The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at leas...
WO/2017/064512A1	COMPOUNDS Anti-angiogenic treatments, for example treatment of ocular neovascularization or cancer, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of treating or preve...
WO/2017/066053A1	COMBINATION ANTIBACTERIAL COMPOSITION AND SHORT-COURSE ANTIBACTERIAL REGIMEN The present invention relates to therapeutic combinations of anti-bacterial agents linezolid, bedaquiline and pretomanid, and optionally with pyrazinamide, in a short-course oral dosage regimen for the treatment of tuberculosis.
WO/2017/059303A1	VINYLOGOUS THIOESTER COMPOUNDS AND METHODS OF USE Provided herein are vinylogous thioester compounds and methods for using the compounds.
WO/2017/053604A1	POTENT ANTIVIRAL PYRAZOLOPYRIDINE COMPOUNDS The present technology provides compounds according to Formulas (I), (II), or (III) useful in inhibiting an enterovirus, paramyxovirus, respiratory virus, flaviviridae virus, bunyaviridae virus, togaviridae virus, or rabies virus in a ce...
WO/2017/050275A1	OXAZOLINES INSECTICIDES AND ACARICIDES AS WELL AS PREPARATION METHOD AND APPLICATION THEREFOR The present invention relates to the technical field of pesticides. Disclosed are oxazolines insecticides and acaricides as well as a preparation method and application therefor. A structural general formula of the oxazolines insecticide...
WO/2017/051353A1	MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the p...
WO/2017/049409A1	COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME Disclosed are compounds of general formula (I) that promote readthrough of a premature termination codon (PTC) of an RNA molecule in a translation system, and their use, alone or in combination with other compounds, such as aminoglycosid...
WO/2017/051354A1	MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the p...
WO/2017/045988A1	ANIONIC POLYMERISATION OF LACTAMS The present invention relates to a method for producing a polyamide (P) via the reaction of a mixture (M) which contains at least one lactam (component (A)), at least one catalyst (component (B)), at least one activator (component (C)) a...
WO/2017/049245A2	COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...
WO/2017/035982A1	DIAZONAPHTHOQUINONE COMPOUNDS, PREPARATION METHOD THEREOF, AND MEDICAL APPLICATIONS The present invention relates to the field of medicinal chemistry, and in particular, to diazonaphthoquinone compounds having antineoplastic activity and a preparation method for the compounds. The compounds can be activated by reduced c...
WO/2017/035566A1	PLASMA POLYMERISED OXAZOLINE COATINGS AND USES THEREOF A plasma polymerised polyoxazoline polymer is disclosed. Also disclosed is a substrate comprising a plasma polymerised polyoxazoline polymer film on a surface thereof, a process for preparing a plasma polymerised polyoxazoline polymer fi...
WO/2017/036404A1	CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine ...
WO/2017/037039A1	ANTIBACTERIAL HETEROCYCLIC DERIVATIVES The invention relates to antibacterial compounds of formula (I), wherein R1, M, R2, R3, and V are as described in the description, to their preparation, to salts thereof, and to their use as pharmaceuticals, to pharmaceutical composition...
WO/2017/030283A1	ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME The present disclosure relates to organic electroluminescent compounds and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present disclosure may be comprised in a light-...
WO/2017/023515A1	CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES Disclosed are compounds of Formula (1), including all stereoisomers, N-oxides, and salts thereof, (Formula (1)) wherein G, J, Q1, R4, Y2, Q2, R5 and Y1 are as defined in the disclosure. Also disclosed are compositions containing the comp...

Matches 451 - 500 out of 9,623	< 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 >