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WO/1993/025207A1 |
3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine and its pharmaceutically and veterinarily acceptable salts have activity in (a) preventing or reducing dependence on, and (b) preventing or reducing tolerance or reverse tolerance to, a d...
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WO/1993/022396A1 |
Fluorine-containing liquid crystal compounds are provided. The compounds comprise a fluorocarbon terminal portion having at least one catenary ether oxygen and a hydrocarbon terminal portion, the terminal portion being connected by a cen...
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WO/1993/022290A1 |
A substituted tertiary amino compound represented by general formula (I) or a pharmaceutically acceptable salt thererof. They have an aromatase inhibiting activity and are useful as a prophylactic and/or therapeutic agent for breast canc...
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WO/1993/019045A1 |
Substituted amides, agricultural compositions containing them and a method to control arthropods in agronomic and nonagronomic environments, the amides having formula (I) wherein X is oxygen or sulfur and Q, G and Y are as defined in the...
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WO/1993/016986A1 |
Azo oxime ethers of general formula (I), in which X is CH or N, R1 is hydrogen, C1-C3alkyl, trifluoromethyl or cylclopropyl and R2 is aryl or heteroaryl, have an activity against phytopathogenic fungi. They can be used in the form of for...
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WO/1993/015041A1 |
This invention relates to new ethanolamine derivatives having gut selective sympathomimetic and anti-pollakiuria activities and represented by general formula (I) wherein R?1¿ is aryl or a heterocyclic group, each of which may be substi...
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WO/1993/010097A1 |
A few nitro compound of formula (I), wherein R?1¿ and R?2¿ are each lower alkyl or lower alkoxy(lower)-alkyl, or (a) is cyclized to form (b), X is -O-, -S- or -NH-, m is an integer 0 or 1, and R?3¿ is carbamoyl, lower alkylcarbamoyl, ...
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WO/1993/009814A1 |
Novel compounds show high affinity for specific cocaine receptors in the brain, particularly dopamine transporter sites, and have formula (I), wherein Y = CH2R3, CO2R2 or (II), R1 = hydrogen, C1-5 alkyl, R2 = hydrogen, C1-6 alkyl, C3-8 c...
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WO/1993/004585A1 |
A herbicidal composition which comprises a phosphonate or phosphinate of formula (I), where R and R', which may be the same or different, each represent straight or branch-chained alkyl of 1 to 12 carbon atoms, and x and y are each 1 or ...
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WO/1993/004051A1 |
2-Aza-2-desamino analogues of 5,8-dideazafolic acid, which analogues have formula (I), wherein x is an aryl or heteroaryl moiety; R1 is H, C1-C4 alkenyl, or C3-C4 alkenyl; and R2 is OH, an L-alpha-amino acid, or a peptide comprising L-al...
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WO/1992/020682A1 |
Substituted anilides of formula (I), wherein Q is one of (Q-1), (Q-2) and (Q-3), and R?1� to R?5�, Y, Z and Z?1� are as defined in the text, arthropodicidal compositions containing such compounds; and a method for controlling arthr...
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WO/1992/017475A1 |
Compounds of formula (I) wherein R1, R2, R7, R8, X, Y, M and L are defined as below. The compounds of formula (I) are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.
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WO/1992/011853A1 |
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosy...
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WO/1992/011249A1 |
Arthropodicidal carboxanilides of formulae (I) and (II) wherein Q, X, X?1¿, Y and G are as defined in the text, arthropodicidal compositions containing said compounds and a method for using the compounds to control arthropods.
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WO/1992/009578A1 |
This invention relates to substituted fused heterocyclic compounds of formula (I), which have utility as herbicides.
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WO/1992/002513A1 |
Heterocyclic compounds of formula (I), wherein R?1¿ and R?2¿ are each lower alkoxy, R?3¿ is substituted amino, etc., Y is CH or N and Z is CH or N, and pharmaceutically acceptable salts thereof which are useful as a medicament.
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WO/1991/004028A1 |
A method of using 1,2,4-benzotriazine oxides, some of which are novel compounds, as radiosensitizers and selective cytotoxic agents is disclosed. These compounds are shown to specifically radiosensitize hypoxic tumor cells. Some are addi...
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WO/1990/014338A1 |
There are disclosed compounds of formula (I); in which R1 represents C(O)YZ or SO2R10, Y represents a single bond, O, NR11 or CO, Z represents hydrogen, alkyl or alkyl substituted by one or more substituents selected from hydroxy, alkoxy...
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WO/1990/009985A1 |
This invention relates to a p-aminophenol derivative of general formula (I) (wherein A, B, Ar, R1, R2 and R3 are as defined above), and its salts, an intermediate for the synthesis thereof, a method for the production of these compounds,...
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WO/1990/004917A1 |
A renin inhibiting compound of formula (I) wherein X is N, O or CH; R1 is absent or a functional group; A and L are independently selected from absent, C=O, SO2 and CH2; D is C=O, SO2 or CH2; Y is N or CH; R2 is hydrogen, loweralkyl or s...
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WO/1989/008647A1 |
A method of using 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents is disclosed. The compounds are shown to specifically radiosensitive hypoxic tumor cells and are additionnally disclosed to be useful as spec...
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WO/1989/005843A1 |
Amphiphilic hemicyanines of formula (I) and polymer materials containing a chromophore covalently bonded according to formula (I), in which W, X, Y, Z, A, Q, n, R1, R2, R3 and V have the meaning given in claim 1, are useful as non-linear...
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WO/1988/008424A1 |
The aromatic amines (I), alkyl amines (II), bicyclic amines (III), cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pha...
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WO/1988/004294A2 |
Compounds of formula (II), where A is (III), (IV), (V), (VI), or (VII); X is O or S; n is 0 or 1; R is H, Cl, F, Br, CH3, OCH3 or OCH2CH3; R'1 is C1-C3 alkyl, allyl or propargyl; R2 is X1R8 or OH; R3 is Cl, F, Br or CF3; R4 is H, Cl, F o...
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WO/1988/002366A1 |
Compounds of formula (I), wherein when X is OH, OR or NR2, n is 0 or 1, and when X is NH2 or NHR, n is 0, where each R is independently an alkyl of 1-4 carbon atoms or a morpholino moiety and may further be substituted with hydroxy, alko...
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WO/1987/005012A2 |
Novel compounds suitable for inclusion in a ferroelectric smectic liquid crystal mixture, having formula (I), where R1 and R2 are independently H, RO, RO1, ROOC, RCOO, RCOOCH(CH3)COO or COOCH(CH3)COOR (R = alkyl) or CN or halogen. Each o...
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WO/1987/004432A1 |
Process for the preparation of benzotriazine oxide from 1-chloro-2-nitro-4-methyl-benzene and monosodium cyanamide, via a guanidinyl compound which is then cyclized. Azapropazone is then made from the benzotriazine oxide produced by the ...
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WO/1987/004433A1 |
Process for the preparation of benzotriazine oxide by the cyclization of a defined class of guanidinyl compounds which themselves are prepared by reaction of a substituted nitro-benzene compound with a cyanamide. In one form of the inven...
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WO/1987/004321A2 |
A method for reducing transpirational moisture loss from plants and increasing crop yield by applying to the plant surface or crop an effective amount of a heterocyclic nitrogen-containing compound. This invention also relates to novel h...
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WO/1986/000072A1 |
Herbicidal 2-aryl-1,2,4-triazine-3,5(2H,4H)-Diones and analogous thiones, where W1 and W2 are oxygen on sulfur; R1 is amino, alkenyl, alkynyl, alkyl or substituted alkyl; R2 is hydrogen, alkenyl, alkynyl, amino, alkyl, substituted alkyl,...
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WO/1983/000864A1 |
Substituted 1,2,4-triazolo AD4,3-b BD-1,2,4-triazines have been found to be effective antiinflammatory and analgesic agents for warm-blooded animals. Pharmacological compositions thereof and methods of using same.
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WO/1983/000939A1 |
A method of forming a photographic azo or azamethine dye image in an exposed photographic silver halide element, the method comprising the steps of a) developing the imagewise exposed material to form an imagewise pattern of oxidised col...
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JP2024517917A |
The present invention provides general formula Ib (In the formula, R1,R2,R3,R4,R5, and Z are as described herein) The present invention relates to novel compounds having the following properties, compositions containing the compounds, an...
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JP7445996B2 |
A compound of formula (I) or (Ia), or a tautomer or a pharmaceutically acceptable salt thereof is provided. Compounds of formula (II) to (V), or a tautomer or a pharmaceutically acceptable salt thereof are also provided. These compounds ...
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JP2024510431A |
The present invention discloses aromatic compounds, their preparation methods and their uses. The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof. The compounds of the present invention sh...
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JP2023542843A |
The present specification relates to a compound represented by Chemical Formula 1 and an organic light-emitting device containing the same.
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JP2023532298A |
The present disclosure generally provides small molecule modulators of NLR family pyrin domain-containing 3 (NLRP3) or pharmaceutically acceptable salts, isotopically enriched analogs, stereoisomers, mixtures of stereoisomers or prodrugs...
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JP2023530709A |
Disclosed herein are thyromimetic compounds that have utility in treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods for the...
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JP2023525349A |
The present invention relates to triazine and pyrimidine (thio)amide compounds, processes and intermediates for their preparation, and their use for controlling phytopathogenic microorganisms such as phytopathogenic fungi.
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JP2023524133A |
Compounds that are mammalian metabolites of agonists of G protein-coupled receptor 139 (GPR139), intermediates used in the synthesis of such metabolites, pharmaceutical compositions containing such metabolites, and schizophrenia such as ...
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JP2023522444A |
The present invention provides diazine and triazine compounds having activity as interferon and interleukin inhibitors, in particular interferon-gamma, tumor necrosis factor (TNF) alpha and interleukin 1 beta, 2, 4, 6, 8, 13 and 17 inhib...
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JP2023522436A |
The present invention provides diazine and triazine compounds having activity as interleukin inhibitors, particularly interleukin-1beta, 2, 4, 6, 8, 13 and 17, and related disorders, particularly Alzheimer's disease, Parkinson's disease,...
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JP2023520006A |
compounds of formula 1 and a pharmaceutically acceptable salt thereof (wherein n, R1, R4, R5、R.6, R7, R8, R9, R10, R11, R14, X2, X3and X12is defined herein) is disclosed. The disclosure also relates to materials and methods for prepari...
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JP2023510835A |
This application discloses compounds of formula (I') or (I), or pharmaceutically acceptable salts, hydrates, solvates, prodrugs, stereoisomers, or tautomers, formula (I) or pharmaceutical compositions comprising compounds of (I) and meth...
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JP2023504214A |
Provided herein are methods of preventing and/or reducing the severity of drug-induced ototoxicity. Provided herein are methods for recovery from hearing loss due to drug-induced ototoxicity. [Selection drawing] Fig. 10A
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JP2023007515A |
To provide a luminescent material having excellent luminous efficiency.In a first embodiment, a luminescent material is provided, comprised of a compound including at least one of a naphthotriazole structure and a naphthotriazine structu...
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JP7200005B2 |
The present invention relates to saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds, or pharmaceutically acceptable salts thereof, having RORγ antagonist activity, pharmaceutical compositions comprising the same, an...
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JP2022545428A |
The present invention discloses halogen-substituted phenyl ether compounds and uses thereof. Specifically, the present invention provides compounds represented by formula (I) or optical isomers, pharmaceutically acceptable salts, prodrug...
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JP7118002B2 |
Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I...
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JP7101728B2 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...
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