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WO/1990/014435A1 |
Analytes, having a characteristic determinant that selectively interacts with a specific binding substance, are determined by coupling a reporter substance to the analyte, or to the specific binding substance, causing complex formation b...
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WO/1989/010758A1 |
Compounds, compositions, their methods of preparation and use in binding bio-affecting substances to the surface membrane of bioparticles, such as eukaryotic cells, without producing appreciable detrimental effect on morphology or physio...
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WO/1989/008256A1 |
A method of preparing a labelled specific binding partner, such as a biological probe in the form of an antibody or oligonucleotide probe, using a protected label, the corresponding unprotected label being susceptible to inactivation, su...
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WO/1989/006231A1 |
This invention concerns chemiluminescent moieties useful as labels in assays and immunoassays, and compositions and assay kits incorporating the moieties. The chemiluminescent moieties are of the type wherein attack by peroxide or molecu...
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WO/1989/002740A1 |
Compounds of formula (I), wherein R1, R2, A and B are defined hereinbelow. The compounds of the present invention inhibit brain acetylcholinesterase and are useful in the treatment of Alzheimer's disease.
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WO/1989/002739A1 |
Compounds of formula (I) wherein R1, R2, A and B are defined hereinbelow. The compounds of the present invention inhibit brain acetylcholinesterase and are useful in the treatment of Alzheimer's disease.
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WO/1988/002256A1 |
A method for treating central nervous system or peripheral nervous system cholinergic deficit states such as Alzheimer's disease in a mammal, said method comprising administering to said mammal an amount of a monoamine acridine derivativ...
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WO/1987/005014A1 |
Compounds represented by general formula (I), (wherein Y-Z represents (II), -CH=CH- or -CH2CH2-, R1 and R2 each represents a substituent, R3 represents hydrogen, alkyl or alkoxy, R4 represents hydrogen, alkyl, optionally substituted alke...
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WO/1987/004163A1 |
Novel compositions of matter which are multifunctional amino zirconium aluminum metallo organic complexes which are comprised of a chemically united complex aluminum moiety, a tetravalent zirconium moiety, and a multifunctional amino aci...
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WO/1986/001203A1 |
Compounds represented by general formula (I) (wherein A represents alkylene, Y-Z represents formula (II), -CH=CH-, -CH2CH2- or formula (III), R1 and R2 each represents a substituent, R3 represents hydrogen, alkyl or alkoxy, R4 represents...
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JP2024040235A |
An object of the present invention is to provide an organic compound with a small refractive index. Alternatively, a novel organic compound having a small refractive index and electron-donating properties is provided. Alternatively, prov...
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JP7430646B2 |
An object is to provide an organic compound with a low refractive index. Alternatively, a novel organic compound with a low refractive index and an electron-donating property is provided. Alternatively, an EL device with high emission ef...
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JP2023553232A |
Visible light absorbing compounds are described. The present compound has a visible light absorption maximum of 430 nm to 480 nm and a full width at half maximum (FWHM) of at least 35 nm and maximum of 150 nm at the visible light absorpt...
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JP2023173608A |
To provide an organic electroluminescent element with high luminous efficacy and a long life.An organic electroluminescent element has a light emission layer containing a luminescent material, a first organic compound as an acceptor mate...
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JP7360135B2 |
The present disclosure concerns use of compounds of formula I, or salts thereof, as reactive matrices for desorption and laser ablation ionization spectrometry. The disclosure further concerns compounds of formula II, or salts thereof, a...
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JP7323539B2 |
Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as...
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JP2023532134A |
Embodiments of methods for treating retinal degeneration in a subject in need thereof are disclosed. In some embodiments, the method comprises a therapeutically effective amount of 3-(dibutylamino)-1-(1,3-dichloro-6-(trifluoromethyl)phen...
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JP2023100644A |
To provide a novel spirobifluorene derivative suitable for use in electronic devices.The present invention provides a spirobifluorene derivative such as 2',7'-di-tert-butyl-4-biphenyl-2-(9,9'-dimethylfluorenyl)-1-
spiro-9,9'-bifluorenyla...
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JP2023523273A |
Redox flow batteries include: catholytes containing radical dications of conjugated heterocyclic carbenium compounds; and anolytes containing neutral radicals of conjugated heterocyclic carbenium compounds; the conjugated heterocyclic ca...
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JP7266583B2 |
The present invention relates to compounds of formula (A), wherein Z is NR10 or O. These compounds represent novel acridinium and xanthylium salts having an unprecedented substituted heterocyclic core. They are useful as fluorescent dyes...
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JP7254298B2 |
Provided is a novel donor-acceptor type compound which emits light even in a solid state. The present invention provides an organic optical material comprising a complex formed from (1) a conjugated molecule having (a) at least one elect...
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JP7253646B2 |
To provide a novel π-conjugated compound capable of improving luminous efficiency of an organic electroluminescent element, for example.The π-conjugated compound is represented by general formula (1) (where Q1 to Q3 each independently ...
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JP7226918B2 |
We disclose novel asymmetric bis-acridines with antitumour activity. These compounds are useful for use in pharmaceuticals, particularly in the treatment or the prevention of neoplasms.
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JP2023007234A |
To provide an object containing a mechanochromism material, a method for producing an object, and a composition.A method for producing an object includes the step of spraying a substrate with a dispersion solution in which a fluorenylide...
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JP7181637B2 |
The invention relates to novel pure organic emitter molecules and optoelectronic devices containing these organic emitter molecules. According to the invention, in the optoelectronic device, after the excitation of an organic molecule, r...
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JP7138799B2 |
A cholinesterase inhibitor polymorph, wherein specifically disclosed are a octahydroaminoacridine succinate polymorph, a corresponding crystal composition and pharmaceutical composition, and applications thereof. The compound octahydroam...
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JP2022537849A |
A polymerizable fused tricyclic compound of Formula I, [Chemical 1] In the formula, R1, R2, R3, m, n, t, and rings B, C, and D describe the compound as defined herein. The compounds absorb various wavelengths of ultraviolet and/or visibl...
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JP2022109792A |
To provide an aqueous two-phase separation liquid allowing organic material to be separated efficiently, and an organic material separation method employing the aqueous two-phase separation liquid.An aqueous solution contains a carboxybe...
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JP2022533390A |
Provided are compounds of formulas I, II, pharmaceutically acceptable salts or esters thereof, capable of binding to an interferon gene stimulating factor (STING) protein and regulating its activity. Methods are also provided that includ...
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JP7096817B2 |
Disclosed are tricyclic heterocyclic compounds having kinase inhibitory activity, pharmaceutical compositions and kits comprising the compounds, and use of the compounds in the treatment of or in medicaments for the treatment of various ...
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JP7085654B2 |
The present invention provides compounds used in the synthesis of chemiluminescent acridinium compounds and methods of producing these compounds. Specifically, methods are provided for the N-alkylation of acridan compounds using alkylati...
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JP7081898B2 |
To provide a novel π-conjugated compound capable of improving luminous efficiency of an organic electroluminescent element, for example.The π-conjugated compound is represented by general formula (1) (where Qto Qeach independently repr...
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JP7057119B2 |
To provide an organic electroluminescent element excellent in light emission efficiency and low in dependency on view angle.An organic EL element 1 according to the present invention is formed from, in the following order: an organic ele...
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JP6995790B2 |
The present invention relates to certain fluorenes, to the use of the compounds in an electronic device, and to an electronic device comprising at least one of these compounds. The present invention furthermore relates to a process for t...
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JP2021183580A |
To provide a fluolenylidene-acridan derivative that has excellent property.Provided is a compound that is represented by 9-(3,6-dimethyl-9H-fluorene-9-yliden)-10-phenyl-9,10-dihydro
acridine, 9-(3,6-difluoro-9H-fluorene-9-yliden)-10-phen...
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JP6970808B2 |
The present invention provides: a photoelectric conversion element which has a photoelectric conversion film that has a narrow half width of the absorption peak; an imaging element; an optical sensor; and a compound. A photoelectric conv...
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JP2021123555A |
To provide a TADF material that comprises an aluminum complex as a metal complex having small singlet-triplet excitation energy difference (ΔEST) and showing efficiently thermally activated delayed fluorescence (TADF).A thermally activa...
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JP6926133B2 |
The present application relates to a compound of a formula (I) which comprises a benzene group that is substituted with a group selected from carbazole derivatives and bridged amines and with an electron attracting group, wherein the two...
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JP6902031B2 |
Provided are the following: a sulfonium salt which does not contain a toxic metal and which exhibits higher cationic polymerization performance and crosslinking performance than a tetrakis(pentafluorophenyl)borate salt; a heat- or photo-...
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JP6901168B2 |
The invention relates to novel pure organic emitter molecules and optoelectronic devices containing these organic emitter molecules. According to the invention, in the optoelectronic device, after the excitation of an organic molecule, r...
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JP6894914B2 |
The present disclosure provides certain compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers and hemoglob...
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JP6866574B2 |
where each of R1 to R8 and R11 to R18 independently represents any one of a hydrogen atom, a halogen atom, a monovalent organic group, the monovalent organic group having a substituent, a polymerizable functional group, and the polymeriz...
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JP6837883B2 |
To provide a method for producing di-substituted dicyano(hetero) aryl with electron-donating groups in high yields.According to a method, in the presence of a palladium catalyst and a base, phthalonitrile derivative and 4-substituted phe...
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JP2021505622A |
Provided with this are compounds that react with reactive lipid species to form non-toxic or active products. Methods of reducing reactive lipid species are also provided. In addition, methods of treating mitochondria in patients with mi...
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JP6789239B2 |
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I):(I) or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein A is a heterocyclic or h...
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JP2020172483A |
To provide an organic electroluminescence element with improved emission efficiency and color purity.The organic electroluminescence element in accordance with one embodiment includes a first electrode and a second electrode opposing to ...
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JP6756614B2 |
An object of the present invention is to provide an organic electroluminescent element containing an organic layer interposed between an anode and a cathode, the organic layer containing at least one light emitting layer, wherein the at ...
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JP6738838B2 |
The invention relates to an organic molecule having exactly two units according to formula I, which are linked to each other by single bond or by a bridge Y, where Y = a divalent group; X = the same or different CN or CF3 in each occurre...
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JP6735665B2 |
Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess ...
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JP6697125B2 |
Disclosed are a 9-phenylacridine macromolecule photosensitizer, and a preparing method and use thereof. The 9-phenylacridine macromolecule photosensitizer comprises at least one of the compounds having a structure as shown in formula (I)...
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