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WO/2023/001905A1 |
The present invention refers to a compound having the formula (I): R1–Z–C≡C–C≡C–R3 (I) and pharmaceutical compositions comprising the same that can be used in prevention, treatment and alleviation of a fungal infection. The i...
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WO/2023/285509A1 |
The present invention relates to a process for the preparation of a compound having formula (I) wherein R is selected from the group consisting of: halogen, (C1-C6)alkoxy, (C1-C6)alkyl, halo(C1-C6)alkyl, and halo(C1-C6)alkoxy, said proce...
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WO/2023/285696A1 |
The present invention relates to a mandelate form of 1-(4-(((6-amino-5-(4- phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)pro
p-2-en-1-one (INN: evobrutinib) and a process of producing the same. Furthermore, the invention relat...
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WO/2023/282319A1 |
This method for producing a polyoxyalkylene alkyl ether acetate comprises a step (A) in which, in the anode part of an electrochemical device comprising a cathode part and an anode part, a polyoxyalkylene alkyl ether is oxidized by an el...
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WO/2022/271456A2 |
The invention relates to the synthetic functionalization of an anthraquinone molecule that is substituted with at least one hydroxyl or amino group. In some aspects of the invention the synthetic functionalization of the anthraquinone mo...
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WO/2022/268840A1 |
Described herein are methods for making intermediates in the production of fragrance ingredients starting from β-farnesene. In particular, methods for making acetylmethylfarnesol and hydroxy-farnesylacetone are described. Methods for ma...
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WO/2022/265429A1 |
The present invention relates to a method for obtaining a compound, after removing at least a portion of insoluble substances or macromolecules from a fermentation broth, by performing one or more of the following steps (a) to (c), and r...
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WO/2022/258807A1 |
The present invention provides a carboxylic acid loaded carboxylic acid salt carrier as a free- flowing powder which is a particulate solid. The compound of invention is stable, biocompatible, and digestible, facilitates a high acid load...
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WO/2022/258732A1 |
The present invention concerns a process for the recovery and purification of glyoxylic acid from a process stream comprising glyoxylic acid and oxalic acid, wherein the process stream comprising glyoxylic acid and oxalic acid is subject...
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WO/2022/253700A1 |
The invention relates to substituted pyrroline-2-ones of the general formula (I) and to their use as herbicides. In formula (I), X, Y, R1, R2 and G represent groups such as halogen, alkoxy, haloalkoxy, alkyl, cycloalkyl and halogen.
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WO/2022/247853A1 |
Among others, the present invention provides for beta‐hydroxybutyrate (e.g., R‐BHB) acids and/or salts with pure biobased carbon content (e.g., 100%as measured by Carbon‐14 analysis. ). The present invention also provides methods f...
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WO/2022/246810A1 |
A preparation method for a polyketone compound having anti-novel coronavirus activity, and an application of a polyketone compound. Solid fermentation is performed on alternaria endophytic fungi Alternaria sp., and a polyketone monomeric...
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WO/2022/251169A1 |
Crystalline salts of psilocin are disclosed. The beneficial and therapeutic uses of the crystalline psilocin salts and of compositions containing the crystalline psilocin salts are also disclosed. The disclosure sets out methods of makin...
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WO/2022/247618A2 |
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WO/2022/241809A1 |
Disclosed in the present invention are a class II major histocompatibility complex (MHC class Ⅱ) expression enhancing compound, and a preparation method therefor and an application thereof. In the present application, experiments prove...
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WO/2022/236396A1 |
The invention relates to a self-preserving anti-microbial pharmaceutical composition, comprising a compound Alpha-1062 or salt thereof, wherein the composition is essentially absent of additional antimicrobial preservatives. The inventio...
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WO/2022/222272A1 |
Disclosed is a synthesis process of 2-methyl-3-methoxybenzoic acid. The synthesis process comprises the following steps: (1) a reductive hydrogenation reaction, involving: using 2-methyl-3-nitrobenzoic acid or methyl 2-methyl-3-nitrobenz...
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WO/2022/225046A1 |
Provided is a composition which has excellent gel formation and thickening characteristics, excellent water retention and conductivity, an excellent stabilization effect in biological materials such as enzymes, in which active ingredient...
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WO/2022/217582A1 |
Disclosed are low-lead and low-arsenic beta-hydroxybutyrate (BHB) salts, comprising lead ranging from 10 to 50 parts per billion (ppb) and arsenic ranging from 10 to 150 ppb. Disclosed also are methods for preparing low-lead and low-arse...
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WO/2022/213493A1 |
The present invention relates to a catalyst for preparing glyceric acid by the efficient catalytic oxidation of glycerol, and a preparation method therefor and the use thereof. The catalyst is Pt1+CCo/CaCoTiO3, wherein the XRD diffractio...
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WO/2022/206399A1 |
Disclosed in the present invention is a copper catalysis-based method for preparing a carboxylic acid compound by means of alcohol oxidation using oxygen as an oxidant. The method specifically comprises: in an organic solvent at a temper...
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WO/2022/199378A1 |
The present invention provides a synthetic method of a bempedoic acid active pharmaceutical ingredient. The synthetic method comprises: subjecting an organozinc reagent (a compound 1) and aldehyde (a compound 2) to an addition reaction i...
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WO/2022/201200A1 |
The present invention relates to light insensitive and thermally stable antimicrobial formulations of electrolytically generated transition metal ions. The specific combination of metal ions gives it a broad spectrum anti-microbial abili...
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WO/2022/193029A1 |
This invention provides the use of specialized pro-resolving mediators (SPMs) for use as melanocyte growth promoters and pro-survival factors. More particularly, the SPM compositions are suitable for promoting melanocyte growth and/or su...
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WO/2022/196790A1 |
The present invention relates to a method for producing an oxide with which an oxide of an organic compound can be obtained efficiently in the presence of a raw material for a Pt/Bi composite catalyst, and a method for producing a Pt/Bi ...
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WO/2022/190599A1 |
Provided is a radiation sensitive resin composition that can form a resist film having sufficient levels of sensitivity, CDU performance, and development residue-inhibiting properties when next generation technology is used. Also provide...
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WO/2022/183281A1 |
Among other things, in general, compositions and methods of treatment for muscular dystrophy and other diseases are disclosed. A method of treatment of a subject is disclosed, in which fatty acid utilization is improved. The method inclu...
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WO/2022/170677A1 |
Providing beta-hydroxybutyrate (BHB) salt granules, comprising BHB salts and fillers. Also providing methods for producing BHB salt granules, wherein the BHB salt granules are prepared by granulation process. The production methods may i...
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WO/2022/165663A1 |
Disclosed in the present application is a method for preparing glycolic acid by hydrolysis of alkoxyacetate. The method comprises: enabling a raw material comprising alkoxyacetate and water to react in the presence of an acidic molecular...
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WO/2022/165662A1 |
Disclosed is a method for preparing glycolic acid and methyl glycolate by hydrolysis of methyl methoxyacetate and methoxyacetic acid. The method comprises: contacting a raw material comprising methyl methoxyacetate, methoxyacetic acid, a...
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WO/2022/169363A1 |
The invention provides a method for the extraction of an organic acid (10) from a mixture (110), the method comprising: an extraction stage comprising providing the mixture (110) to a sorbent (150); an elution stage comprising passing an...
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WO/2022/154537A1 |
The present invention relates to a process of recovering 3-hydroxypropionic acid, comprising the steps of: forming crystals of 3-hydroxypropionate in a concentrated solution including 300 g/L or more of 3-hydroxypropionic acid in the pre...
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WO/2022/150917A1 |
The invention relates to crystalline forms of Alpha-1062 gluconate (scheme I: (I)). In one aspect, the invention relates to a crystalline solid form of Alpha-1062 gluconate (Form A), wherein said crystalline form has prominent peaks at 3...
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WO/2022/149161A1 |
The present application relates to a process for preparation of Bempedoic acid of formula (I) or its pharmaceutically acceptable salts thereof. The present application also relates to a novel intermediates of formula (II) and formula (II...
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WO/2022/141739A1 |
A method for producing α-calcium sulfate hemihydrate whiskers by using a fermentation liquor for producing lactic acid by means of a calcium salt method as a raw material, and synchronously recovering a lactic acid monomer. The method c...
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WO/2022/133719A1 |
Relates to a method for producing glycolic acid by selectively hydrogenating glyoxylic acid using a catalyst comprising at least one transition metal element, the glycolic acid produced, as well as the uses thereof.
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WO/2022/138670A1 |
Provided are a compound, polymer, composition, film-forming composition, pattern formation method, method for forming insulating films, and compound production method, that yield a resist that exhibits excellent exposure sensitivity. T...
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WO/2022/135433A1 |
A method for producing glycolic acid by selectively hydrogenating glyoxylic acid using a catalyst comprising at least one transition metal element, the glycolic acid produced, as well as the uses thereof.
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WO/2022/136346A1 |
The invention relates to ferulic acid granules and the production method thereof. The invention is suitable for use in paritcular in the fields of food, cosmetics and flavours.
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WO/2022/138659A1 |
Provided is a method for producing a fluorovinyl ether compound capable of suppressing the generation of by-products. The method for producing a fluorovinyl ether compound of the present invention is a method for producing a fluoroviny...
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WO/2022/131073A1 |
Provided is a hydroxyalkanoic acid crystal production method characterized by including a step for freeze-drying a solution containing hydroxyalkanoic acid, and (1) the content of an R-body being 95-100 mass% or more, or (2) the content ...
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WO/2022/110821A1 |
Disclosed are a carboxylic acid compound as represented by formula I, a preparation method therefor and the use thereof. When the carboxylic acid compound is used as an extraction agent for the extraction and separation of metal ions, th...
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WO/2022/115326A1 |
Described herein are methods of making the PPARδ agonist compound (E)-2-(4-((3-(4-fluorophenyl)-3-(4-(3-morpholinoprop-1-yn-1-
yl)phenyl)allyl)oxy)-2-methylphenoxy)acetic acid, including salt forms thereof.
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WO/2022/106893A1 |
The present invention is directed to Form A of monohydrate of calcium oxybate, a pharmaceutically acceptable composition thereof, its method of making, and use thereof.
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WO/2022/107889A1 |
Provided is a fluoropolymer comprising a monomer (I) represented by general formula (I), wherein the content of a polymerization unit (I) based on the monomer (I) is 40 mol% with respect to the total polymerization units constituting the...
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WO/2022/104245A2 |
Provided herein is a compound which is particularly suitable for use as a cannabinoid, as an emulsifier for a cannabinoid, in a formulation comprising the compound and in a method of treatment using the compound. The compound is defined ...
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WO/2022/098881A1 |
Disclosed are compounds and methods to enhance the resolution of inflammation and inflammatory diseases comprising novel compounds derived from conjugated specialized pro-resolving lipid mediators (SPMs). These compounds are useful in pr...
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WO/2022/099018A1 |
The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3'-(3-(((R)-3-hydroxypyrrolidin-1-yl)meth
yl)-1,7-naphthyridin-8-ylamino)-2,2'-dimethylbiphenyl-3-yl)b
enzo[d]oxazol-5-yl)methyl)pyrrolidine-...
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WO/2022/080905A1 |
The present specification relates to an apparatus for vaporizing lactic acid. According to a method and an apparatus for vaporizing lactic acid, of the present invention, the quantity of lactic acid oligomers can be reduced within a shor...
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WO/2022/077851A1 |
The present invention discloses a 1,4-dihydropyridine chiral hybrid hydrogenation reagent, a preparation method and an application thereof. The 1,4-dihydropyridine chiral hybrid hydrogenation reagent has a structure represented by formul...
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