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WO/2016/063286A1 |
A fluid composition comprises a triglyceride, having at least one alpha-branched fatty acid residue, wherein each alpha-branched fatty acid residue comprises at least one saturated or mono- unsaturated alkyl chain having a total number o...
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WO/2016/063296A1 |
The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl- polyprenylated phloroglucinol ...
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WO/2016/058081A1 |
A solid form of Nilotinib hydrochloride, which exists as a co-crystal of nilotinib hydrochloride and levulinic acid having a molar ratio of nilotinib hydrochloride to levulinic acid of 1:2, and a process for the preparation of the co-cry...
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WO/2016/055819A1 |
The invention provides a new process for the preparation of treprostinil of formula (I) and its salts using several new intermediates during the building of the ringsystem.
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WO/2016/054726A1 |
The present invention concerns the use of compounds for preventing and/or treating diabetes, for modulating glucose, insulin, and/or triglyceride levels; for reducing blood glucose level; for maintaining or increasing insulin level; for ...
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WO/2016/054728A1 |
The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating bone remodeling, for stimulating the differentiation and mineralization of osteoblasts, for ...
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WO/2016/054725A1 |
The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating the differentiation and mineralization of osteoblasts, or for inhibiting bone resorption in ...
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WO/2016/042573A1 |
The present invention provides a process for preparation of {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6- trimethyl)phenyl-3,7-dimethyl-nona-2,4,6,8}tetraenoate, an acitretin intermediate of formula (VI) with trans isomer ≥97%, comprising of reac...
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WO/2016/041351A1 |
The present invention relates to the technical field of organic chemistry, specifically an asymmetrical hydrogenation reaction of an α-ketonic acid compound, the scheme being as shown by formula (I), wherein R1 is a phenyl, a substitute...
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WO/2016/043264A1 |
A method for producing a vapor composition containing lactic acid, whereby: at vaporization, the formation of by-products such as acetaldehyde and carbon monoxide due to the heat decomposition of lactic acid and the like can be regulated...
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WO/2016/040223A1 |
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulato...
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WO/2016/038033A1 |
The invention relates to a method for producing a compound of (IV), wherein R1 is an alkyl group having 1 - 4 carbon atoms, comprising the step of reacting cyclohexene with hydrogen peroxide and an alcohol R1OH in the presence of a catal...
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WO/2016/040225A1 |
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulato...
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WO/2016/031803A1 |
[Problem] To provide a magnesium hydroxide-based solid solution which has smaller primary particles and secondary particles and improved reactivity with acid, when compared with conventional magnesium hydroxide (Mg(OH)2), improves the fl...
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WO/2016/023929A1 |
The invention discloses a method for the preparation of trifluoroacetylacetic acid in its dehydrated form with a low content of the hydrate of trifluoroacetoacetic acid.
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WO/2016/022943A2 |
Compounds derived from biomass, e.g., cellulose and lignins, methods of forming such compounds and polymers and products formed using such compounds.
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WO/2016/019579A1 |
Provided is a method for synthesizing an anti-inflammatory compound; and also provided is a method for preparing the intermediate compound of formula 2, which comprises contacting ethyl propiolate with lithium bromide in order to produce...
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WO/2016/020603A1 |
Process for producing a calix-[z]-arene in which: - a calix-[z]-arene in which R1=R2=R3=R4=X1=X2=X3=X4=H is supplied, - step (a): - this calix-[z]-arene is treated with an alkylating agent transmitting the R4 residue, so as to obtain a r...
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WO/2016/019868A1 |
Provided are a citric acid salt of a thiadiazole derivative DPP-IV inhibitor, and preparation method, pharmaceutical composition and use thereof for treating and/or preventing diseases benefiting from DPP-IV inhibition, particularly for ...
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WO/2016/012965A2 |
The present invention relates to substituted phenyl alkanoic acid compounds designated as the compound of Formula (I) (as described herein) or a tautomer, a stereoisomer, a geometrical isomer, a pharmaceutically acceptable salt, a pharma...
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WO/2016/013245A1 |
The purpose of the present invention is to provide: a catalyst material which is loaded with fine gold particles and has excellent catalytic activity; and a method for producing this catalyst material. A catalyst material according to th...
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WO/2016/010538A1 |
Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the com...
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WO/2015/199729A1 |
The present invention provides tromethamine salt of (Z)-7-[3,5-Dihydroxy-2-((E)-3-hydroxy-5-phenyl-pent-1-enyl)-
cyclopentyl]-hept-5-enoic acid in crystalline Form 1 and amorphous form. This compound is may also be referred to as "tromet...
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WO/2015/188727A1 |
Disclosed is a new method for preparing an azetidinone compound represented by formula (I). The carboxylic ketoester represented by formula (II) serves as the raw material and is subjected to Grignard addition, stereoselective dehydratio...
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WO/2015/189244A1 |
The present invention relates to a method for the acetylation of an aqueous solution of lactic acid to (S)-2-acetyloxypropionic acid. The process comprises in particular removing water from the solution of lactic acid and reacting lactic...
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WO/2015/188005A1 |
The invention relates to the preparation and characterization of novel salts of (R)-isometheptene and crystalline forms thereof; moreover, the invention describes the use of the novel salts alone or in combination with other therapeutic ...
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WO/2015/186690A1 |
The present invention is useful for inhibiting decomposition of a glycan chain released in a β-elimination reaction of an O-linked glycan chain from glycoprotein by anhydrous hydrazine.
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WO/2015/183132A1 |
A salt of zinc or copper (II) which can be used as a biocide, having the general formula CH2=C(R1)COO-M-OCOR2(OH)m(COOH)n, where M is Zn or Cu, R1 is selected from the group including hydrogen and methyl, R2 is a substituted С1-С5 alky...
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WO/2015/181023A1 |
The method can be used for preparing a p-hydroxymandelic compound comprising at least a step of condensing at least one aromatic compound bearing at least one hydroxyl group and of which the para position is free, with glyoxylic acid, th...
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WO/2015/177179A1 |
A process to prepare a compound of Formula (I) wherein R3, R4 and R5 are each selected independently from hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxyl, and wherein the alkyl, alkenyl, alkynyl, and alkoxyl may be optionally substit...
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WO/2015/176153A1 |
The present application relates to amorfrutin analogs and uses as PPAR modulators for the treatment of metabolic syndrome, obesity, hyperlipidemia, elevated fasting blood glucose, elevated blood pressure, low HDL cholesterol, type 2 diab...
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WO/2015/172149A1 |
Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polygl...
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WO/2015/169876A1 |
The invention relates to a compound of general formula (I) wherein: R1 is a hydrogen atom or a C1 to C4 alkyl radical; R2 is a C1 to C4 hydroxyl or alkoxyl radical; and R3 and R4 are independently a hydrogen atom or a C1 à C4 alkyl radi...
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WO/2015/155536A1 |
A process for the production of a complex of lactic acid and either ammonia or an amine, comprising: a) reacting a stream rich in saccharide with sodium hydroxide to produce a reaction mixture comprising sodium lactate; b) contacting at ...
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WO/2015/155533A1 |
A process for producing sodium lactate, lactic acid, or a derivative of lactic acid selected from the group consisting of an alkyl lactate, oligomeric lactic acid, lactide, an alkyl lactyllactate, polylactic acid, and a complex of lactic...
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WO/2015/155535A1 |
A process for producing an alkali metal lactate comprising: a) reacting a stream rich in saccharide with barium hydroxide to produce a first reaction mixture comprising barium lactate; and b) contacting at least a portion of said first r...
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WO/2015/152127A1 |
When crystallizing lactic acid to collect purified lactic acid crystals and recirculating the mother liquor to the crystallization step, by distilling a lactic acid-containing solution and using the lactic acid collected from the vapor s...
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WO/2015/152173A1 |
Provided is a method that recovers high yields of an acid of an anionic fluorine-containing emulsifier from a basic ion exchange resin to which is physisorbed a nonionic surfactant and to which is adsorbed the anionic fluorine-containing...
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WO/2015/144993A1 |
The present invention relates to catalytic conversion of ketoacids, including methods for increasing the molecular weight of ketoacids, the method comprising the steps of providing in a reactor a feedstock comprising at least one ketoaci...
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WO/2015/144856A1 |
The present invention relates to catalytic conversion of ketoacids, including methods for increasing the molecular weight of ketoacids, the method comprising the steps of providing in a reactor a feedstock comprising at least one ketoaci...
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WO/2015/144994A1 |
The present invention relates to thermal conversion of ketoacids, including methods for increasing the molecular weight of ketoacids, the method comprising the steps of providing in a reactor a feedstock comprising at least one ketoacid....
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WO/2015/138955A2 |
This invention relates to a process for making phenolic fatty acid compounds having a reduced phenolic ester content. The invention also relates to method for chemically bonding a phenolic resin with a non-phenolic polymer (e.g., a synth...
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WO/2015/134352A1 |
The invention describes processes to selectively remove or reduce the mineral acid content substantially from compositions comprising a solvent and levulinic acid, wherein the levulinic acid was derived from the reaction between various ...
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WO/2015/134349A1 |
The invention describes processes to convert biomass char, such as levulinic acid process char, into useful products.
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WO/2015/120115A1 |
Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.
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WO/2015/113906A1 |
The present invention relates to novel ionic liquids comprising polyethercarboxylate groups as anions, alkyl ammonium groups as cations, a process of preparation of said ionic liquids and its use in high duty lubricant.
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WO/2015/111699A1 |
The present invention provides: the production of a hydroxylated fatty acid by a hydration reaction using a novel enzyme which is derived from a lactic acid bacterium and of which the substrate is a fatty acid; and a method for producing...
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WO/2015/111726A1 |
Provided is a method capable of suppressing the corrosion of glass in contact with a liquid containing fluoride ions, or a condensate of gas vaporized therefrom, without needing to add an alkaline substance and without additional restric...
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WO/2015/111529A1 |
Provided are: a near-infrared absorbing composition which provides a cured film that has high transmittance in the visible light region and exhibits high shielding performance in the near-infrared region; a near-infrared blocking filter;...
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WO/2015/106636A1 |
A demethylivabradine salt, and a preparation method therefor and uses thereof. The demethylivabradine salt is a pharmaceutically acceptable salt, and the pharmaceutically acceptable salt comprises citrate, hydrobromide, sulfate, phosphat...
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