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WO/2024/082327A1 |
A method for efficiently purifying phospholipid from coenzyme Q10 fermented powder, comprising the following steps: 1) mother liquor culture, 2) seed tank culture, 3) fermentation tank culture, 4) fermented liquor centrifugation, 5) high...
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WO/2024/050725A1 |
The application discloses methods useful for the synthesis of certain 2, 3, 5, 6-alkyl-1, 4-benzoquinone compounds, including 2, 3, 5-trimethyl-6-nonylcyclohexa-2, 5-diene-1, 4-dione, and synthetic intermediates for the production thereof.
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WO/2024/054871A1 |
The application discloses methods useful for the synthesis of certain 2,3,5,6-alkyl-1,4-benzoquinone compounds, including 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione, and synthetic intermediates for the production thereof.
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WO/2024/013633A1 |
The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl hali...
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WO/2023/161206A1 |
The present invention provides an electrochemical process for producing a benzoquinone compound, which is versatile in converting hydroquinone and a broad range of phenols into benzoquinones in an attractive yield and selectivity without...
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WO/2023/150151A1 |
Disclosed herein are embodiments of compounds that exhibit Crk-like protein inhibition. The compound embodiments can be used to suppress or prevent tumor cell growth, augmenting immune cell response in a subject having, or suspected of h...
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WO/2023/120552A1 |
The present specification discloses a reduced coenzyme Q10 product which does not require the formulation of reduced coenzyme Q10 and in which the oxidation of reduced coenzyme Q10 is suppressed. Also, the present specification discloses...
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WO/2023/120558A1 |
The present specification discloses a method for storing reduced coenzyme Q10 (QH), the method being capable of suppressing oxidation. The first embodiment of the present invention relates to a method for storing QH, the method includi...
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WO/2023/120557A1 |
The present description discloses a packaged body of reduced coenzyme Q10, which eliminates the need for formulating the reduced coenzyme Q10 into a preparation, does not undergo the oxidation of the reduced coenzyme Q10 and can be store...
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WO/2023/120555A1 |
The present description discloses a favorable means for suppressing oxidation of reduced coenzyme Q10 (QH) without requiring formulation of QH. At least one embodiment of the present invention relates to a method for storing reduced co...
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WO/2023/120553A1 |
The present description discloses a preferred means for preventing the oxidation of reduced coenzyme Q10 (QH) without requiring the formulation of QH into a preparation. One or more embodiments of the present invention relates to: a me...
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WO/2023/102759A1 |
The present invention relates to a composition comprising 2-amylenyl-anthraquinones and to its preparation method. The composition can be used for producing a composition comprising 2-amylanthraquinone isomers with specific molar ratio.
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WO/2023/096111A1 |
The present application relates to a novel quinizarine derivative, wherein the quinizarine derivative has a bromodomain extra-terminal (BET) protein inhibition ability, and thus can be used in a pharmaceutical composition for preventing ...
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WO/2023/073080A1 |
The present invention relates to a process for preparing aromatic acyl derivatives of formula (I) using methanesulfonic acid. The invention further relates to methods for preparing biological active ingredients, such as paracetamol.
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WO/2023/016459A1 |
Disclosed are a novel organic alkoxide agglomerate, and a preparation method therefor and an application and thereof. The agglomerate has the following molecular formula: (ZOR)12YmQn. The novel organic alkoxide agglomerate has good catal...
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WO/2023/285509A1 |
The present invention relates to a process for the preparation of a compound having formula (I) wherein R is selected from the group consisting of: halogen, (C1-C6)alkoxy, (C1-C6)alkyl, halo(C1-C6)alkyl, and halo(C1-C6)alkoxy, said proce...
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WO/2022/271456A2 |
The invention relates to the synthetic functionalization of an anthraquinone molecule that is substituted with at least one hydroxyl or amino group. In some aspects of the invention the synthetic functionalization of the anthraquinone mo...
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WO/2022/257994A1 |
Disclosed are a cryptotanshinone derivative, a preparation method therefor and an application thereof in anti-myocardial fibrosis. The new cryptotanshinone derivative has a structural formula of (I). Preliminary experimental results show...
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WO/2022/233417A1 |
The present invention relates to the manufacture of benzoquinones, in particular to the manufacture of a potassium salt of a benzoquinone, such as 2,5-dihydroxy-l,4-benzoquinone di-potassium salt. The potassium salt of a benzoquinone is ...
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WO/2022/184904A1 |
The present invention relates to a method for the preparation of a compound having formula (I) wherein: • R1, R2, R3, and R4 are in particular H or halogen, • R5 is in particular (C1-C6)alkyl, • R6 is a group of formula -CH=CH2 or ...
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WO/2022/129185A1 |
The present invention generally relates to the production of vanillin and related compounds (such as aromatic carboxylic acids, quinones, etc.) involving the oxidative cleavage of aromatic compounds (such as lignin, lignols, cinnamic aci...
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WO/2022/104763A1 |
Provided process for cyclization of 2- (4' -alkylbenzoyl) benzoic acid to corresponding 2-alkylanthraquinone in the presence of an improved zeolite catalyst, which is capable of increasing the conversion of 2- (4' -alkylbenzoyl) benzoic ...
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WO/2022/057603A1 |
The present invention relates to a method for extracting coenzyme Q10 from a fermentation broth of coenzyme Q10, comprising subjecting the fermentation broth of coenzyme Q10 to pre-processing, leaching, crystallization, dissolution, chro...
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WO/2022/015181A1 |
The invention relates to a method and intermediate compounds for the preparation of menaquinone MK-7. The method for the preparation of menaquinone MK-7 is characterized in that, it comprises coupling of a compound of formula (11) with a...
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WO/2021/238947A1 |
Disclosed is a method for preparing a quinone compound. The present invention provides a method for preparing a quinone compound, the method comprising the following step: in the presence of a base, subjecting a compound as shown in form...
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WO/2021/234078A1 |
The present invention relates to the photooxidation of 2,3,6-trimethyl- phenol to yield 2,3,5-trimethylbenzoquinone using methylene blue as photo- sensitizer in a solvent mixture of water and alcohols using light of the high wave- length...
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WO/2021/234077A1 |
The present invention relates to the photooxidation of 2,3,5-trimethyl- phenol to yield 2,3,5-trimethylbenzoquinone using methylene blue as photo- sensitizer in a solvent mixture of water and alcohols using light of the high wavelength r...
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WO/2021/234080A1 |
The present invention relates to the photooxidation of phenolic compounds to the respective quinoid compounds using methylene blue as photosensitizer in a solvent mixture of water and alcohols using light of the high wavelength range of ...
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WO/2021/232543A1 |
Disclosed is a method for separating coenzyme Q10 by means of using a supercritical fluid chromatography system, the method comprising: (1) starting a supercritical fluid chromatography system and setting system parameters; (2) once the ...
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WO/2021/156406A1 |
The present invention relates to a process for preparing 8-hydroxy-9,10-dioxo-anthracene-1- carboxylic acid. It also relates to a method for preparing an anthraquinone derivative comprising a step for preparing 8-hydroxy-9,10-dioxo-anthr...
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WO/2021/122437A1 |
The present invention relates to the formation of 2,3,5-trimethylhydro- quinone from 2,3,6-tri¬methyl¬phenol comprising the steps a) the oxidation of 2,3,6-trimethylphenol to 2,3,5-trimethylquinone. b) the reduction of 2,3,5-trimethylq...
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WO/2021/120522A1 |
Disclosed in the present invention is a preparation method for vitamin K1 having different cis-trans isomer proportions and an intermediate halogenated phytol thereof. The method comprises: carrying out a halogenation reaction on a raw m...
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WO/2021/118485A1 |
The invention relates to the production of thymoquinone, a bioactive material proven to be effective in cancer studies using Ay-Yildiz heterogeneous catalyst obtained by the hydrothermal method, one of the environmentally friendly methods.
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WO/2021/073456A1 |
Provided are a class of macrocyclic and cage-like molecules based on a biphenylarene and derivative compounds, a synthesis method therefor and the use thereof. A series of new macrocycles and molecular cages are obtained in a high yield ...
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WO/2021/071372A1 |
The invention relates to an improved process of vitamin K2 derivatives preparation via the alkylation of the menadione-cyclopentadiene adduct.
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WO/2021/036386A1 |
A simulated moving bed continuous chromatography system and an application thereof, and a method for purifying coenzyme Q10. The simulated moving bed continuous chromatography system comprises at least four chromatographic columns sequen...
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WO/2021/000246A1 |
Provided is a Bacillus subtilis natto ST-1008, deposited under the accession number CGMCC No. 17894. Also provided is a method for producing MK-7. The method comprises: culturing the Bacillus subtilis natto of CGMCC No. 17894 in a cultur...
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WO/2020/211572A1 |
The present invention relates to a method for preparing 2-alkyl anthracene, comprising the following step: separating 2-alkyl anthracene from a reaction product of an anthracene alkylation reaction, the anthracene alkylation reaction bei...
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WO/2020/130080A1 |
The purpose of the present invention is to provide a method for synthesizing a p-quinone using one of alkoxy-substituted benzenes as a starting material. The present invention relates to a method for producing a compound of formula (II...
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WO/2020/105500A1 |
The objective of the present invention is to provide a processing method for a working solution, wherein the amount of anthraquinones is increased by regenerating, into anthraquinones, by-products derived from anthraquinones and having n...
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WO/2020/103118A1 |
A process for manufacturing a compound of formula (II), said process comprising a step of reacting a compound of formula (I) in the presence of a zeolite catalyst and a solvent, (I), (II) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are ind...
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WO/2020/055678A1 |
The present application discloses methods for the efficient preparation of high purity compounds of the Formula I, and their methods of use.
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WO/2020/029017A1 |
A system and method for purifying coenzyme Q10 are provided. The method includes: passing a CoQ10-containing crude product through a first chromatographic column to obtain a first CoQ10-containing intermediate product. The method further...
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WO/2020/015316A1 |
Disclosed are a method for extracting and purifying coenzyme Q10 and coenzyme Q10 prepared thereby. The method extracts and purifies coenzyme Q10 from coenzyme Q10 bacteria and comprises the steps of extracting, precipitating, decoloring...
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WO/2019/201819A1 |
The present invention relates to the oxidation of alkylated p-hydroquinones. It has been found the oxidation by oxygen or an oxygen containing gas mixture in the presence of a transition metal salt, which does not comprise any polydentat...
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WO/2019/201820A1 |
The present invention relates to the oxidation of alkylated p-hydroquinones. It has been found the oxidation by aqueous hydrogen peroxide in the presence of a transition metal salt, which does not comprise any polydentate ligand bound to...
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WO/2019/158514A1 |
Disclosed is a process for the oxidation of at least one chroman (C1) in a solvent mixture comprising at least two solvents or in a C-bearing solvent, with a gaseous compound comprising, essentially consisting of, or consisting of oxygen...
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WO/2019/127829A1 |
A fermentation production method for an oxidized coenzyme Q10 and a high-content oxidized coenzyme Q10 prepared therefrom, which are characterized in that the oxidation-reduction potential ORP of a fermentation broth is controlled to be ...
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WO/2019/128060A1 |
The present application relates to a method for extracting a coenzyme Q10 and phospholipids from a coenzyme Q10 fermentation bacterial powder. The method is characterized in that a mixed solvent having a three-dimensional Hansen solubili...
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WO/2019/028933A1 |
The present invention relates to the technical field of pharmaceuticals, and discloses an antibacterial application of a Dryopteris fragrans phloroglucinol compound flavaspidic acid BB. The present invention provides for the first time a...
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