Title:
FERMENTATION PRODUCTION METHOD FOR OXIDIZED COENZYME Q10, AND HIGH-CONTENT OXIDIZED COENZYME Q10 PREPARED THEREFROM
Document Type and Number:
WIPO Patent Application WO/2019/127829
Kind Code:
A1
Abstract:
A fermentation production method for an oxidized coenzyme Q10 and a high-content oxidized coenzyme Q10 prepared therefrom, which are characterized in that the oxidation-reduction potential ORP of a fermentation broth is controlled to be -50-300 mV during the fermentation process of a production strain, the oxidation-reduction potential ORP of the fermentation broth preferably being controlled to be 50-200 mV. The method enables the content of the oxidized coenzyme Q10 in the coenzyme Q10 produced by microorganisms to reach more than 96%.
More Like This:
| JPS54157895 | MICROBIOLOGICAL OXIDATION |
Inventors:
YUAN SHENFENG (CN)
YU HONGWEI (CN)
CHEN ZHAOFENG (CN)
ZHU YONGQIANG (CN)
MIN YI (CN)
LI YONG (CN)
HU BAISHAN (CN)
QIU GUISHENG (CN)
YU KAI (CN)
YU HONGWEI (CN)
CHEN ZHAOFENG (CN)
ZHU YONGQIANG (CN)
MIN YI (CN)
LI YONG (CN)
HU BAISHAN (CN)
QIU GUISHENG (CN)
YU KAI (CN)
Application Number:
PCT/CN2018/074822
Publication Date:
July 04, 2019
Filing Date:
January 31, 2018
Export Citation:
Assignee:
ZHEJIANG NHU CO LTD (CN)
UNIV ZHEJIANG (CN)
HEILONGJIANG NHU BIOTECHNOLOGY COMPANY LTD (CN)
SHANGYU NHU BIOLOGICAL CHEMICAL CO LTD (CN)
UNIV ZHEJIANG (CN)
HEILONGJIANG NHU BIOTECHNOLOGY COMPANY LTD (CN)
SHANGYU NHU BIOLOGICAL CHEMICAL CO LTD (CN)
International Classes:
C12P7/66; C07C46/10; C12R1/01
Domestic Patent References:
| WO2008100782A2 | 2008-08-21 |
Foreign References:
| CN102876743A | 2013-01-16 | |||
| CN105420417A | 2016-03-23 | |||
| CN104561154A | 2015-04-29 | |||
| CN102965272A | 2013-03-13 |
Other References:
YAMADA, Y. ET AL.: "Application of Fuzzy Control System to Coenzyme Q10 Fermentation", JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, vol. 24, no. 1, 31 December 1991 (1991-12-31), pages 94 - 99, XP055624120
SAKATO, K. ET AL.: "Agitation-Aeration Studies on Coenzyme Q10 Production Using Rhodopseudomonas spheroide s", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 31 December 1992 (1992-12-31), pages 19 - 28, XP002967047
SAKATO, K. ET AL.: "Agitation-Aeration Studies on Coenzyme Q10 Production Using Rhodopseudomonas spheroide s", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 31 December 1992 (1992-12-31), pages 19 - 28, XP002967047
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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