Acyclic or Carbocyclic Compounds

Matches 451 - 500 out of 2,569	< 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 >

Document	Document Title
WO/1998/052552A1	PROCESS FOR THE PREPARATION OF POLYAMINES AND POLYAMINE DERIVATIVES Disclosed are processes for the preparation of compounds of the formula (I): H�2?N-(CH�2?)�n?-A-(CH�2?)�m?-NH�2?, or (II): H�2?N-(CH�2?)�n?-NH-C(=NR?1�)-NH-(CH�2?)�m?-NH� �2?, wherein n and m are each independent...
WO/1998/045257A1	THIO DERIVATIVES AS NAALADASE INHIBITORS The present invention relates to thio derivatives of formula (I), wherein X is selected from the group consisting of (II), (III) and (IV), Y is CR�1?R�2?, NR�3? or O and R, R�1?, R�2? and R�3? are as defined in the claims, th...
WO/1998/035935A1	ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM Novel compounds useful as active ingredients of pesticides are disclosed. Acrylonitrile compounds of formula (I) or their salts, wherein Q is Qa, Qb, Qc or Qd, Y is =C(R�4?)- or =N-, R�1? is alkyl, haloalkyl, etc., each of R�2? and...
WO/1998/021178A1	N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS N-arylsulfilimine compounds, such as S,S-dimethyl-N-(2,6-dichlorophenyl)sulfilimine, were prepared and found to catalyze the reaction of aromatic sulfonyl chloride compounds, such as 2-chlorosulfonyl-7-fluoro-5-ethoxy[1,2,4]-triazolo[1,5...
WO/1998/019997A2	DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY This invention pertains to improved antiviral activity of 6,6-disubstituted-5,6-dihydropyran-2-ones caused by judicious placement of certain polar substituents at the 3 and/or 6 positions. The same substituents which enhance the cellular...
WO/1998/019676A1	METHOD FOR TREATMENT OF GLUTAMATE RELATED DISORDERS A method of using a compound of formula (I) wherein R?1�, R?2�, R?3�, X and n have any of the meanings defined in the specification, to antagonize glutamate binding, or to treat glutamate-related disorders is provided. Novel compou...
WO/1998/018758A1	SODIUM SALT OF [POLY-(2,5-DIHYDROXYPHENYLENE)]-4-THIOSULPHURIC ACID OF LINEAR STRUCTURE AS REGULATOR OF CELL METABOLISM AND PRODUCTION METHOD THEREOF Sodium salt of [poly-(2,5-dihydroxy-phenilene)]-4-thiosulfonic acid, being a cyclo-linear polymer, is proposed as the regulator of a cell metabolism. There are provided for the production of the claimed preparation: interaction of para-b...
WO/1998/014425A1	ISOCYANATE DERIVATIVES AND THEIR PRODUCTION This invention describes a method of forming bisulphite adducts of aliphatic isocyanates bearing an aromatic moiety by mixing an aqueous solution of a bisulphite adduct forming agent with a solution of an isocyanate bearing an aromatic m...
WO/1998/013342A1	SULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, AND CURABLE COMPOSITIONS Sulfonium salts represented by general formula (I) which can cure cationically polymerizable compounds at 100 �C or below and can give one-pack mixtures thereof with cationically polymerizable compounds excellent in storage stability; ...
WO/1998/008566A1	MANIPULATIONS OF NITROSATIVE AND OXIDATIVES STRESS IN THE TREATMENT OF DISEASE Mammals are treated for infections or for conditions associated with pathologically proliferating mammalian cell growth (for example, certain cancers, restenosis, benign prostatic hypertrophy) by administration of a manipulator of nitros...
WO/1998/009002A1	PREPARATION OF ONIUM HYDROXIDES IN AN ELECTROCHEMICAL CELL Electrochemically preparing onium hydroxides by (A) providing a cell comprising an anode (11), a cathode (12) and one or more unit cells between the anode and the cathode, each unit cell comprising: four compartments defined by, in seque...
WO/1997/046521A1	NITRATE ESTERS AND THEIR USE FOR NEUROLOGICAL CONDITIONS Aliphatic nitrate esters having a sulfur or phosphorus atom 'beta' or 'gamma' to a nitrate group and their congeners having efficacy as neuroprotective agents are described. Preferred nitrate esters may be synthesized by nitration of a 3...
WO/1997/045115A1	PHARMACEUTICAL FOR TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof.
WO/1997/033866A1	'beta'-ANILINOETHANETHIOL COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND PROCESS FOR PREPARING 3,4-DIHYDRO-2H-1,4-BENZOTHIAZINE COMPOUNDS THEREFROM 'beta'-anilinoethanethiol compounds of general formula (1) (wherein R is hydrogen or optionally substituted alkyl or aryl; R1 is optionally substituted alkyl or optionally substituted aryl); a process for the preparation of 'beta'-anilin...
WO/1997/027749A1	NITROSATED AND NITROSYLATED 'alpha'-ADRENERGIC RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS AND THEIR USES Disclosed are nitrosated and nitrosylated 'alpha'-adrenergic receptor antagonists, compositions of an 'alpha'-adrenergic receptor antagonist ('alpha'-antagonist), which can optionally be substituted with at least one NO or NO2 moiety, an...
WO/1997/022612A1	MANUFACTURE OF GLYPHOSATE SALTS The trimethylsulphonium salt of N-phosphonomethylglycine is prepared by reacting N-phosphonomethylglycine, preferably in the form of a solid, with an aqueous solution of trimethylsulphonium carbonate or trimethylsulphonium bicarbonate or...
WO/1997/022590A1	NITRATION OF AROMATIC COMPOUNDS A method of nitrating electron-deficient carbocyclic or heterocyclic aromatic compounds such as pyridines, diazines and triazines and benzenoid aromatics having electron-withdrawing substituents involves first reacting the aromatic speci...
WO/1997/015552A1	PHENYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR USE IN PRODUCING THEM AND AGENTS CONTAINING THEM Disclosed are phenylacetic acid derivatives of formula (I) in which the substituents and the index have the following meanings: X is NOCH3, CHOCH3, CHCH3; Y is O or NR; R1, R independently of one another stand for hydrogen or C1-C4 alkyl...
WO/1997/008140A1	N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION N-sulfonyliminodithio compounds have the formula (I), in which R1 and R2 stand for optionally substituted alkyl, alkenyl or alkinyl, and Ar stands for optionally substituted aryl; also disclosed are processes for preparing these compound...
WO/1997/008141A1	NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD Sulfonium salt compounds represented by general formula (I): wherein R1 and R2 represent each alkyl, hydroxy, alkoxy, alkylcarbonyl, aromatic carbonyl, aromatic thio or halogeno; R3 represents alkyl; R4 represents optionally substituted ...
WO/1997/005868A1	USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS The present invention is directed to new therapeutic uses of compounds of formula (I) wherein X and Y are oxygen, sulfur, or (CR'R'')n wherein n is 1 to 4; R is hydrogen, alkyl, or benzyl; R1 and R2 are phenyl, substituted phenyl, naphth...
WO/1997/005106A1	THE PREPARATION OF FLUORINATED ORGANIC COMPOUNDS A method of producing fluorinated organic compounds such as organic sulphur pentafluorides. The method includes the steps of converting a compound such as R1-S-S-R2 into R1SF5 by reaction with an inert solvent of R1-S-S-R2 and elemental ...
WO/1996/040627A2	THIOCATIONIC LIPIDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF Lipid molecules bearing a cationic charge are described. These cationic lipids are useful in the delivery of biomolecules, such as oligonucleotides, nucleic acids, peptides, diagnostic imaging agents, proteins and drug molecules. In the ...
WO/1996/037459A1	PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID DICHLORIDE The present invention refers to a process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride, comprising the reaction in heterogeneous phase between 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid and...
WO/1996/032946A1	COMPOSITIONS AND METHODS TO PREVENT TOXICITY INDUCED BY NONSTEROIDAL ANTIINFLAMMATORY DRUGS Nonsteroidal antiinflammatory drugs which have been substituted with a nitrogen monoxide group; compositions comprising: (i) a nonsteroidal antiinflammatory drug, which can optionally be substituted with a nitrogen monoxide group and (ii...
WO/1996/026185A1	REAGENT, COMPOUND AND METHOD FOR NUCLEOPHILE PERFLUOROALKYLATION, AND RESULTING DERIVATIVES A reagent comprising a compound of formula (I): Rf-M(X)(Z)n-Y-R, wherein R is a hydrocarbon radical advantageously having at most 10 carbon atoms and being selected from alkyls and aryls; Rf is a radical of formula (II): R1-(C'XI'2)m-CF2...
WO/1996/018607A1	ANILINE DERIVATIVE HAVING THE EFFECT OF INHIBITING NITROGEN MONOXIDE SYNTHASE A compound represented by general formula (1) or possible stereoisomers and optical isomers thereof, and medicinally acceptable salts of these compounds, wherein R1 represents SR6 or NHR7; R6 represents C1-C6 alkyl, etc.; R7 represents h...
WO/1996/018608A1	ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY A compound represented by general formula (1),zor possible stereoisomers and optical isomers thereof, and medicinally acceptable salts of these, (wherein R1 represents SR6 or NR7R8; R6 represents C1-C6 alkyl, etc.; R7 represents hydrogen...
WO/1996/011183A1	N-(ORTHO-SUBSTITUTED BENZYLOXY)IMINE DERIVATIVES AND THEIR USE AS FUNGICIDES, ACARICIDES OR INSECTICIDES The present invention relates to oxime ethers of general formula (I) and to their isomers and isomer mixtures which are possible in which (a) X is an N atom and Y is an oxygen atom or NH, or (b) X is CH and Y is an oxygen atom, in which ...
WO/1995/029925A1	THIOETHER COMPOUNDS FOR USE IN PREPARING BIFUNCTIONAL CHELATING AGENTS FOR THERAPEUTIC RADIOPHARMACEUTICALS A compound consisting essentially of a multidentade ligand including at least two thioether groups for being complexed to Rhodium-105 in specific activities that are sufficiently high for use in formulating therapeutic 105Rh-radiopharmac...
WO/1995/024387A1	SULFONIUM SALT COMPOUND AND POLYMERIZATION INITIATOR A sulfonium salt compound represented by general formula (I) and a curable composition containing the compound, wherein R1 represents C1-C18 alkyl, hydroxy, C1-C18 alkoxy, C1-C18 alkylcarbonyloxy or halogen, and n represents 0, 1, 2 or 3...
WO/1995/017373A1	HIGHLY PACKED POLYCATIONIC AMMONIUM, SULFONIUM AND PHOSPHONIUM LIPIDS The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful f...
WO/1995/016676A1	ARTHROPODICIDAL PENTAFLUOROTHIO SUBSTITUTED ANILIDES Arthropodicidal compounds, compositions and use of compounds having formula (I), wherein Q, X, Y, R1 and m are as defined in the text.
WO/1995/014011A2	5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of the...
WO/1995/014012A1	5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of the...
WO/1995/009620A1	SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS Novel sulfoximine and sulfodiimine matrix metalloproteinase inhibitors of formula (I), wherein: R1 is selected from the group consisting of lower-alkyl, hydroxy lower-alkyl, amino lower-alkyl, carbamoyl lower-alkyl, lower-alkyl carbonyl,...
WO/1994/029271A1	NOVEL SULFONIUM SALT COMPOUND AND POLYMERIZATION INITIATOR A sulfonium salt compound represented by general formula (I), useful as a cationic polymerization initiator, wherein R1 represents benzyl, phenyl, etc.; R2, R3 and R4 represent each hydrogen, alkyl, etc.; R5 represents hydrogen, alkyl, p...
WO/1994/026701A1	PROCESS FOR PREPARING NG-MONOALKYL-L-ARGININE AND RELATED COMPOUNDS A process is disclosed for the preparation of N_G-monoalkyl-L_-arginine and related compounds and salts thereof, for example N_G-monomethyl-L-arginine by reacting N-alkylaminoiminomethane sulphonic acid of formula (II) with an amino acid...
WO/1994/022817A1	PROCESS FOR THE PREPARATION OF ARYL- AND HETEROARYLSULPHURPENTAFLUORIDES A process for the preparation of arylsulphurpentafluorides and heteroarylsulphurpentafluorides comprises reacting an aryldisulphide or heteroaryldisulphide with silver difluoride under anhydrous conditions at a temperature of at least 10...
WO/1994/021606A1	PENTAFLUOROSULPHANYLPHENYL AND PENTAFLUOROSULPHANYLPYRIDIL SUBSTITUTED HETEROAROMATIC COMPOUNDS WITH INSECTICIDAL OR ACARICIDAL ACTIVITY Compounds with insecticidal or acaricidal activity have formula (IA) or (IB), wherein Ra represents hydrogen or from 1 to 4 optional substituents and Rb represents from 1 to 3 optional substituents and wherein A represents an optionally ...
WO/1994/014436A1	RETROVIRAL PROTEASE INHIBITING COMPOUNDS A retroviral protease inhibiting compound of formula (A) is disclosed.
WO/1994/011460A1	REFRIGERANT COMPOSITIONS INCLUDING 1,1,2-TRIFLUOROETHANE Refrigerant compositions include mixtures of 1,1,2-trifluoroethane and a second component wherein the second component is (CF3)2NF, (CF3)3N, N(CHF2)2(CF3), N(CH2F)(CF3)2, SF5CF2H, SF5C2F5, HFC-236ca, HFC-236cb, HFC-236ea, HFC-254cb, HFC-...
WO/1994/007183A1	ULTRAVIOLET LIGHT SENSITIVE ONIUM SALTS AND THE USE THEREOF AS PHOTOINITIATORS A composition of matter including an onium salt and a method of forming images. The onium salt has a chromophore which absorbs ultraviolet radiation, an S, Se, As, N or P atom which is free of substituents exhibiting a higher energy occu...
WO/1994/003551A1	DIALKYL ALKOXY PHENYL SULFONIUM SALT CATIONIC INITIATORS This invention relates to C14 to C20 alkoxy monophenyl sulfonium salt initiators having formula (I), wherein R is C14 to C20 alkyl; R1 and R2 are each independently C4 to C20 alkyl and X- is a non-basic, non-nucleophilic anion, which ini...
WO/1993/025522A1	PROCESS FOR PRODUCING THIOUREA DIOXIDE AND BLEACHING OF PAPERMAKING PULP WITH THIOUREA DIOXIDE PRODUCED THEREBY An economical process for producing thiourea dioxide fluid with reduced chemical loss and energy consumption by mixing a combination of thiourea and a peroxide, a combination of thiourea, a peroxide and a reaction catalyst, or a combinat...
WO/1993/024634A1	DIPEPTIDYL PEPTIDASE-I, CLONING IT, AND THERAPEUTIC AGENTS CONTAINING INHIBITORS THEREOF Therapeutic agents and methods for the treatment of immunologically mediated diseases and malignancies of myeloid cell or lymphoid cell origin. These particular methods utilize the characterization of particular activation mechanisms imp...
WO/1993/012068A1	S-NITROSOTHIOLS AS SMOOTH MUSCLE RELAXANTS AND THERAPEUTIC USES THEREOF S-nitrosothiols exert a potent relaxant effect, mediated both by guanylate cyclase, and a cGMP-independent mechanism, upon non-vascular smooth muscle. Such types of smooth muscle include airway, gastrointestinal, bladder, uterine and cor...
WO/1993/009162A1	HYPERBRANCHED ARAMIDS Hyperbranched aramids, made from an aromatic aminodicarboxylic acid or an aromatic diaminocarboxylic acid, and optionally an aromatic aminocarboxylic acid are disclosed. The hyperbranched aramids are useful as aids for the processing of ...
WO/1993/006089A1	N-PHENYLPHRAZOLES AS INSECTICIDES AND ACARICIDES Compounds with insecticidal activity have formula (I) wherein R1 is hydrogen, halogen, or a group NR4R5 wherein R4 and R5 are independently selected from hydrogen or alkyl; R2 is a group -S(O)nR6 wherein n is 0, 1 or 2 and R6 is a haloal...
WO/1992/022526A1	SULPHONYL FORMAMIDRAZONES, METHODS OF PREPARING THEM, AGENTS CONTAINING THEM, AND THEIR USE AGAINST PLANT PESTS The invention concerns sulphonyl formamidrazones of general formula (I) and their tautomers of general formula (II), in which R?1� is an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl or phenyl group or a resi...

Matches 451 - 500 out of 2,569	< 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 >