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WO/2013/065189A1 |
The present invention provides a method for producing a reduction reaction product, wherein recovery of the reaction solvent and/or distillation is carried out after adding a nitrogen-containing compound into a reaction liquid of a reduc...
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WO/2013/066181A1 |
Compound or a salt or solvate thereof for use as an imaging ligand for the detection of aggregated amyloid-β or for use as a medicament according to the formula (I): wherein R1 and R3 may be the same or different optionally substituted ...
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WO/2013/060821A1 |
The present invention relates to a structured catalyst based on sintered metal fibers (SMF) coated by a non-acidic metal oxide layer impregnated with Pd and Agnanopartides, characterized in that the ratio of the Pd:Ag is 1:1 to 10:1, as ...
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WO/2013/037737A1 |
The invention relates to a method for producing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reacting styrene with isopropanol at elevated temperature, wherein 2-methyl-4-phenyl-2-butanol is obtained; and b) hydrogenating 2-methyl-4-p...
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WO/2013/036095A1 |
An amidoamine compound that has properties such as modifying the viscosity of asphalt, promoting adhesion between asphalt and stone aggregate, maintaining the mechanical properties of the asphalt mixture and preventing ageing of the asph...
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WO/2013/026724A1 |
The present invention relates to compounds of formula (IA) wherein QA is QA1 or QA2 P is P1, heterocyclyl or heterocyclyl substituted by one to five Z; and wherein A1, A2, A3, A4, G1, Z, R1, R2, R3 and R4 are as defined in claim 1; or a ...
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WO/2012/177357A9 |
The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume r...
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WO/2013/026726A1 |
The present invention provides compounds of formula I wherein Q is Q1 or Q2; A1, A2, A3 and A4 are independently of each other C-H, C-R7, or nitrogen; R1 is C1-C8haloalkyl; R2 is aryl or aryl substituted by one to five R11, or heteroaryl...
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WO/2013/013709A1 |
The current invention provides and improved method for hydrolyzing alpha- chlorinated toluene compounds comprising the steps of: -providing an alpha-chlorinated toluene compound of formula (I) wherein at least one of R1, R2 and R3 is CI ...
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WO/2013/011155A2 |
The invention discloses a method for the preparation of medetomidine starting from 1-bromo 2,3-dimethylbenzene and aceton.
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WO/2013/013238A2 |
Compounds and compositions, which can be use for example, for treating cancer, are described herein.
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WO/2013/011156A2 |
The invention discloses a method for preparation of 2-(2,3-dimethylphenyl)-1-propanal from bromo 2,3-dimethylbenzene and aceton, its use in perfumes and its use for the preparation of medetomidine.
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WO/2013/008093A1 |
The present application provides terpene analogues of Formula 1 and methods and uses thereof for treating neurological conditions such as pain in general and neuropathic pain specifically.(Formula I) (I) wherein: Y is a C1 to C20 alkylen...
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WO/2013/001026A1 |
The present invention concerns a process for the preparation of a compound of formula (I) in the form of any one of its stereoisomers or mixtures thereof, and wherein R represents a C2-C10 group of formula CORa wherein Ra is an alkyl or ...
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WO/2013/001027A1 |
The present invention concerns a process for the preparation of a compound of formula (I) in the form of any one of its stereoisomers or mixtures thereof, wherein R represents a C2-C10 group of formula CORa wherein Ra is an alkyl or alke...
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WO/2012/172120A2 |
The invention discloses 2-(2,3-dimethylphenyl)-1-propanal, a method for its preparation from -bromo 2,3-dimethylbenzene and aceton, its use in perfumes and its use for the preparation of medetomidine.
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WO/2012/172119A2 |
The invention discloses a method for the preparation of medetomidine starting from 1-bromo 2,3-dimethylbenzene and aceton.
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WO/2012/160189A1 |
Compounds of formula (1) wherein R is hydrogen and the bond between C-2 and C-3 together with the dotted line represents a double bond, or R is - CH2 - and together with C-2 and C-3 represents a cyclopropane ring and the bond between C-2...
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WO/2012/159223A1 |
Compounds of formula (I) wherein R is hydrogen and the bond between C-2 and C-3 together with the dotted line represents a double bond, or R is - CH2 - and together with C-2 and C-3 represents a cyclopropane ring and the bond between C-2...
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WO/2012/153684A1 |
Provided is a ruthenium complex that is represented by general formula (1*) and is useful as an asymmetric reduction catalyst. (In the formula, * is an asymmetric carbon atom; R1 is an arenesulfonyl group, and the like; R2 and R3 are a p...
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WO/2012/137460A1 |
The present invention provides: a novel ruthenium complex which has excellent catalytic activity with respect to reactivity in the reduction of a multiple bond, in particular, in the asymmetric reduction of a carbonyl compound, enantiose...
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WO/2012/121301A1 |
[Problem] To provide a process for producing a fluorine-containing substituted compound, which can produce the fluorine-containing substituted compound under temperature conditions that can be achieved industrially, using a simple appara...
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WO/2012/121156A1 |
The invention relates to a method for producing an alkene derivative represented by general formula [4] (wherein R1 represents an aryl group having, as a substitute, an alkyl group, an alkoxy group, a halogen atom, an amino group, or a n...
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WO/2012/122152A1 |
Disclosed are a process and catalysts useful for carrying out asymmetric methlyallylations. The catalysts used in the invention have the formula (IV): wherein X1, X2, R3 and R4 are as defined herein. Compounds made by the process of the ...
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WO/2012/113495A1 |
The invention relates to a method for recovering high-grade biodegradable fatty alcohols from waste fats and/or waste oils. To this end the waste oils or fats are first of all split by hydrolysis. After cleaning with short-chain alkenes ...
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WO/2012/110375A1 |
The present invention concerns a process tor the preparation of a compound of formula (I) in the form of any one of its stereoisomers or mixtures thereof, and wherein the dotted line may represents an additional bond and Ra represents a ...
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WO/2012/108472A1 |
Disclosed are: a novel substance which functions as a solid Lewis acid catalyst in the presence of water; a process for producing the same; use thereof as a solid Lewis acid catalyst; and a method for conducting a chemical reaction in an...
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WO/2012/105431A1 |
This method for producing a β-fluoroalcohol comprises a step wherein an α-fluoroester is caused to react with a hydrogen gas (H2) in the presence of a specific ruthenium complex (one represented by general formula (2), especially one r...
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WO/2012/103799A1 |
Disclosed are (2R,3R)-3-(3-substituted phenyl)-2-methyl-n-pentanamide compounds shown as formula I, their preparation methods thereof, wherein the substituents are described in the description, and their uses in the manufacture of Tapent...
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WO/2012/102247A1 |
This catalyst for a hydrogen transfer reaction contains a ruthenium complex represented by general formula (1) (in the formula, R1 and R2 are each independently a monovalent hydrocarbon group. Two R1s may bond to each other to form a div...
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WO/2012/090976A1 |
Provided is an alicyclic alcohol compound which can be used as a raw material for a compound perfume, and which has excellent floral-green-like aromas which are crisp and fresh; also provided are a manufacturing method for the same, and ...
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WO/2012/084810A1 |
The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of specific ruthenium catalysts, or pre-catalysts, in hydrogenation processes for the reduction of ketones and/or aldehydes into the...
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WO/2012/086808A1 |
A process for producing an aromatic alcohol or a heterocyclic aromatic alcohol, characterized by comprising reacting an aromatic amine or a heterocyclic aromatic amine each having at least one group -CHR1NR2R3 (wherein R1, R2 and R3 inde...
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WO/2012/074012A1 |
The present invention is characterized by being a nucleoside analog represented by one of general formulas (1) to (10) or a salt thereof. (R1, R2, and R3 may be the same as or different from each other and are each selected from a group ...
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WO/2012/069004A1 |
Disclosed are a preparation method for a key intermediate of tapentadol: (1R, 2R)-1-ethyl-2-methylbenzene ethane compound, and a method for applying the key intermediate in the preparation of tapentadol and a derivative thereof.
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WO/2012/065571A1 |
The present invention relates to a chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof. The chiral spiro-pyridylamidophosphine compound is a compound having a structure of Formula (I), a ...
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WO/2012/045707A1 |
A process for preparing homoallyl alcohols by catalysed reaction of alkenes with aldehydes or ketones, characterized in that the reaction is effected in the presence of noncovalently immobilized ionic liquid phase catalysts in the gas ph...
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WO/2012/041215A1 |
The present invention concerns a novel transition metal complex having nitrogen-containing heterocyclic ligands and phosphine ligands, the preparation thereof and the uses thereof in asymmetric catalytic hydrogenation and hydrogen transf...
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WO/2012/032211A1 |
Dendritic structures based on tetraarylmethane. The invention relates to dendrimers of formula I, formed by radially stiffened tetrahedral units of tetraphenylmethane of type AB3, interlinked with each other by means of rigid linear conn...
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WO/2012/022837A1 |
The invention relates to a pharmaceutical composition for human and/or veterinary use for transdermal delivery, comprising at least one active drug substance selected from zwitterionic drug substances, non-steroidal anti-inflammatory dru...
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WO/2012/023546A1 |
The purpose of the present invention is to provide a process by which hydrogen or heavy hydrogens can be easily produced without using large-scale equipment and a process by which hydrogenation (protiation, deuteration or tritiation) can...
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WO/2012/020076A1 |
1-(3/4-isobutyl-1/6-methylcyclohex-3-enyl)methanols and derivatives thereof having appreciable floral and hesperidic odor notes, their use as fragrance ingredient and perfumed products comprising them.
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WO/2012/021013A2 |
The present invention aims to provide a novel biphenyl compound or a pharmaceutically acceptable salt thereof, a method for preparing the novel biphenyl compound or pharmaceutically acceptable salt thereof, and a pharmaceutical compositi...
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WO/2012/019106A2 |
Disclosed herein are compounds useful as modulators of an NMDA receptor. Further disclosed are methods of modulating an NMDA receptor using these compounds, and methods of treating various NMDA-receptor disorders, such as, for example, s...
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WO/2011/163325A1 |
The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume r...
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WO/2011/150347A2 |
Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB recept...
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WO/2011/138747A1 |
The invention relates to the chemistry of fragrances and to the field of perfumery. More specifically, the invention relates to compounds with a woody note, having general formula (I), in which: - the ring with 6 carbon atoms is saturate...
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WO/2011/136645A1 |
The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label,and to the us...
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WO/2011/108509A1 |
Disclosed is an iron oxide-based complex oxide catalyst, wherein an alkali metal is supported by a complex oxide of iron oxide and at least one of zirconia, titania or alumina. Also disclosed is a method for producing allyl alcohol and p...
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WO/2011/100667A1 |
The invention provides a surfactant and/or a cleaning composition comprising a microbially produced branched fatty alcohol or a derivative thereof. The invention also provides a household cleaning composition and a personal or pet care c...
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