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WO/2009/065244A1 |
Branched, highly-substituted C9-C13 homoallyl alcohols of formula (I) in which R1 and R2 are selected from H or Me and R3 is selected from H, Me and Et. The compounds are useful in fragrance applications in which a floral note is desired.
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WO/2009/053883A1 |
The present invention concerns a process for the preparation of a compound of formula (I), wherein the dotted line is a single bond and n is 1 or the dotted line is a double bond and n is 0, and wherein the relative configuration is as s...
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WO/2009/050587A1 |
The present invention relates to a process of preparing a compound of Formula I: (I) Formula I Wherein R1 is defined in the specification. Compounds of Formula I are useful for treating disorders of the central nervous system, including ...
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WO/2009/047258A1 |
A compound of general f ormula (I) wherein R1, R2, R3, and R4 are, independently, a hydrogen atom or an optionally substituted linear or branched C1-C6 alkyl or C2-C6 alkenyl group, provided that when each of R1, R2, and R3 are a hydroge...
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WO/2009/031532A1 |
Disclosed is a method for producing a polyvalent aralkyl alcohol by hydrolyzing an aralkyl halide having two or more haloalkyl groups. The aralkyl alcohol is produced by: mixing an aralkyl halide with a high-temperature/high-pressure wat...
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WO/2009/027108A1 |
The present invention relates to a new process for preparing estrogen-antagonistic 11 β-fluoro-17α-alkylestra-1,3,5(10)-triene-3,17-diols of the general formula (I) having a 7α-(ξ-alkylamino-ω-perfluoroalkyl)alkyl side chain and to ...
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WO/2009/023980A1 |
A method for the preparation of cyclopropyl carbinols by cyclopropanation of unsaturated alcoholates, utilising a reagent system selected from (A) magnesium metal and dibromomethane, and (B) dibromomethane and a tertiary Grignard reagent...
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WO/2009/025728A1 |
Substituted alditol or carbohydrate compounds having a specified general formula (I) are provided. A. method for synthesizing such substituted alditol or carbohydrate compounds is also provided. wherein n is 0, 1, or 2; and R is an alken...
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WO/2009/009916A1 |
The invention refers to conjugated secondary alkatrienol derivatives, a method of their production and to flavour and perfume compositions comprising them.
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WO/2008/153112A1 |
Disclosed are 6,8,10-undecatrien-3-ol and 6,8,10-undecatrien-4-ol. The compounds have an aroma with a woody green note and also have a natural, fresh fruit-like aroma. Therefore, a perfume composition containing each of the compounds is ...
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WO/2008/149370A2 |
A general method is disclosed for the conversion of aldehydes and alkenes to the corresponding carboxylic acids and 1,2-diols. The method is carried out in a catalyst-free aqueous medium under an atmosphere of oxygen or oxygen containing...
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WO/2008/146826A1 |
A process for efficiently and economically producing an optically active styrene oxide compound having a target configuration. The process for producing an optically active styrene oxide compound comprises subjecting a racemate of a styr...
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WO/2008/142482A2 |
The present invention relates to compositions comprising at least omega-3 lipid compounds substituted at the 2-positions having therapeutic activity. More specifically, the present invention relates to a composition comprising at least o...
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WO/2008/132552A2 |
Omega-3 lipid compounds of the general formula (1): wherein P represents a hydrogen atom, Formulas (a), (b), (c) or (d) and (e), Y is a C14-C22 alkenyl group with at least one double bond, having E and/or Z, configuration;., or any pharm...
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WO/2008/120475A1 |
Disclosed is a method for producing an alcohol from a lactone or a carboxylic acid ester, which enables to produce an alcohol from a lactone or a carboxylic acid ester under relatively mild conditions with high yield and high catalytic e...
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WO/2008/120174A1 |
The present invention relates to the use of Ru complexes, having a pentamethyl- cyclopentadienyl and a cyclooctadine as ligands, together with some acidic additives for improving the selectivity in the 1,4-hydrogenation of sorbol into th...
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WO/2008/117871A1 |
Disclosed is a redox catalyst containing a compound represented by the formula (I) below or a derivative thereof. (In the formula, X1 and X2 independently represent a hydrogen atom, a halogen atom, an optionally substituted hydroxy group...
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WO/2008/111371A1 |
Disclosed is a method for highly efficiently obtaining an optically active alcohol from a carbonyl compound highly enantioselectively. Also disclosed is a ligand used in such a method. Specifically, an optically active alcohol is obtaine...
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WO/2008/108105A1 |
A specific quinone compound, which contains two quinone groups at ortho positions and has such a characteristic that an electron transfer is caused during a reversible oxidation-reduction reaction, is oligomerized or polymerized. Consequ...
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WO/2008/101603A2 |
The invention relates to a structured catalyst based on sintered metal fibers (SMF) coated by a ZnO layer impregnated with Pd-nanoparticles, reactions of organic starting material with hydrogen in the presence of said catalyst and vitami...
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WO/2008/099966A1 |
Disclosed is a method for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol, which is characterized by comprising the following steps (A)-(D). Step (A): a step for fluorinating 2,3,5,6-tetrachloroterephthalic acid dichloride Step (B):...
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WO/2008/098774A1 |
The invention relates to a process of reacting a primary allylic alcohol with a compound containing a) a metal selected from the group consisting of Ag, Au, Ce, Mn, Ni, Ru, Re, Zn and Co preferably Ag and b) an oxidant like TEMPO (2,2',6...
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WO/2008/095724A1 |
The present invention relates to a process for isomerizing a pent-1-en-3-ol to a mixture of the isomers Z-pent-2-en-1-ol and E-pent-2-en-1-ol by reacting the pent-1-en-3-ol (1) in a multiphase system comprising an aqueous phase and an or...
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WO/2008/095646A1 |
The present invention relates to a process for lithium exchange reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
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WO/2008/098077A2 |
The invention provides compounds of Formula (I) : wherein R1 and R2 have any of the values or specific values defined herein, as well as composition comprising such compounds and therapeutic methods comprising the administration of such ...
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WO/2008/092981A1 |
The present invention comprises the preparation of a novel odorant (1), preparation thereof from (1R) - (-) - nopol (2) and use thereof as a sandalwood type ingredient in the production of perfumery compositions. Obtaining (1) from (2) i...
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WO/2008/088074A1 |
Disclosed is a method for the purification of β-phenylethyl alcohol, which comprises supplying β-phenylethyl alcohol to be purified to a distillation column to produce β-phenylethyl alcohol in a purified form as a side-cut fraction. I...
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WO/2008/077610A1 |
The invention relates to the asymmetric (transfer) hydrogenation of a prochiral keton, prochiral imine, oxime, oxime derivative, hydrazone or hydrazone derivative, using a transition metal catalyst, characterized in that as a catalyst is...
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WO/2008/073646A2 |
A process for preparation of protriptyline hydrochloride from 5- dihydrobenzocycloheptatriene of formula (1) by coupling with chloropropyl alcohol in the presence of excess n-butyl Lithium in tetrahydrofuran under inert atmosphere, follo...
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WO/2008/056768A1 |
A process for the production of metal catalyst carrying carbon/ethylenediamine composites, characterized by reacting carbon carrying a metal catalyst with ethylenediamine in water or a liquid mixture of water with a water-soluble organic...
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WO/2008/049823A1 |
The invention relates to a process for the hydrogenation of an alkylaryl ketone which process comprises contacting a feed containing an alkylaryl ketone with hydrogen in trickle-flow mode in the presence of a heterogeneous hydrogenation ...
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WO/2008/049922A2 |
The present invention describes a novel process for the preparation of montelukast acid, and its pharmaceutically acceptable salts and esters.
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WO/2008/038801A1 |
A method of synthesizing a diol or a polydiol by reductively coupling carbonyl compounds in a solvent with the use of 12CaO.7Al2O3 having 1019 cm-3 or more but not more than 2.3x1021 cm-3 electrons per cage as a reducing agent. A method ...
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WO/2008/035212A2 |
The invention relates, in general, to an improved process for preparing compounds (e.g., 3-(3-trifluoromethylphenyl)propanal (Compound III, below)), which are key intermediates for jjhe synthesis of cinacalcet its salts and/Or solvates t...
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WO/2008/035086A2 |
The present invention relates to the synthesis of leukotriene receptor agonist compounds and to novel intermediates employed in their preparation. Leukotriene agonists are used in the treatment of asthma, as well as other conditions medi...
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WO/2008/023658A1 |
A process for isomerization of alkyl Grignard reagents, by which easily available alkyl Grignard reagents can be easily and efficiently isomerized into alkyl Grignard reagents different from the starting ones in the position in the alkyl...
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WO/2008/023780A1 |
It is intended to provide a method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a...
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WO/2008/018822A1 |
The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing said intermediates, to intermediates used in said processes, and to the use of said intermediates in the preparation of pharmac...
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WO/2008/017183A1 |
The present invention relates to campholytic aldehyde condensates of formula (I) wherein R1 - R5 have the same meaning as given in the specification. It furthermore relates to a method of their production and to fragrance compositions an...
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WO/2008/009841A1 |
Compound of the general formula (I), wherein X is a group CHO, CH2OH, CH2OR, CH2OC(O)R or CH(OR1) (OR2) and each of R, R1, R2 represents an alkyl or alkylene chain having 1, 2, 3, 4, 5, or 6 carbon atoms, wherein said chain is linear or ...
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WO/2008/001668A1 |
It is intended to provide an alcohol compound having a natural lily of the valley aroma but little woody smell, which restricts the utilization thereof as a starting material in preparing a fragrance, and a method of producing the same. ...
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WO/2008/001826A1 |
A process for the production of a halogen-substituted benzenedimethanol represented by the formula (2), comprising the step of reacting a halogen-substituted terephthalic acid diester represented by the formula (1), a metal borohydride c...
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WO/2007/147163A2 |
A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subjec...
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WO/2007/142189A1 |
Disclosed is an organic lithium zincate as a novel zinc ate complex. Also disclosed are a method for producing such an organic lithium zincate and use of such an organic lithium zincate. Specifically disclosed is t-butyl diethyl lithium ...
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WO/2007/129664A1 |
Disclosed is a chiral compound represented by the following formula (Ia) or (Ib). (Ia) (Ib) [In the formulae, R represents an optionally substituted alkyl group or an optionally substituted aryl group; and R' represents a hydrogen atom, ...
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WO/2007/120502A1 |
A compound of formula (I): wherein R is -CH2OH, -C(O)H, -C(OR3)2H, -C(OR4)(OH)H, -CH=NC6H4C(O)OR5 or -CH=NR6; R1 and R2 are each independently H or CH3; R3 and R4 are each independently H or a straight or branched aliphatic group having ...
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WO/2007/111783A2 |
A process for producing an alkenyl alcohol from a diol is disclosed. The process comprises dehydrating a diol in the presence of a catalyst comprising cerium oxide supported on a carrier. The carrier has a surface area in the range of 0....
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WO/2007/111091A1 |
Disclosed is a method for producing an alcohol wherein an alcohol is produced by hydroformylation of an organic compound having an unsaturated carbon bond by carbon oxide and hydrogen while using a catalyst which is obtained by combining...
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WO/2007/107869A2 |
The present invention relates to lipid compounds of the general formula (I): wherein - n=0-2, - R1 and R2 are the same or different and may be selected from a group of substituents consisting of a hydrogen atom, an alkyl group, a halogen...
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WO/2007/105668A1 |
The invention provides a novel immobilized Lewis acid catalyst which exhibits high catalytic activity in an aqueous solution and which permits recovery and reuse or long-term continuous use. The invention relates to an immobilized Lewis ...
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