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WO/2023/203473A1 |
The object of the present invention is a novel class of compounds and the pharmaceutical compositions containing them as active ingredients. The compounds according to the invention are effective in the prevention or treatment of disorde...
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WO/2023/202554A1 |
Disclosed are a chiral aryl propionic acid derivative and a pharmaceutical composition thereof, and a use. The chiral aryl propionic acid derivative is as shown in formula (I), and the definition of each group is given in the description...
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WO/2023/184031A1 |
Methods and uses for the treatment or prevention of stroke in a mammal including in a human, including administering a therapeutically effective amount of bucillamine or a pharmaceutically acceptable salt or solvate thereof to a mammal i...
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WO/2023/190166A1 |
The present invention provides: a cationic lipid that can be used as a nucleic acid delivery carrier having excellent intercellular behavior; a lipid membrane structure including the same; a nucleic acid introduction agent and a pharmace...
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WO/2023/190767A1 |
[Problem] The present invention provides: a polyether ether ketone decomposition method which efficiently decomposes a polyether ether ketone; and a novel compound which is synthesized using a starting material that is a decomposition pr...
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WO/2023/186149A1 |
The present invention relates to the technical field of biomedicines, and particularly disclosed are a lipid compound, a composition containing the same, and use thereof. The lipid compound has a structure represented by formula (I) or f...
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WO/2023/180824A1 |
A thiol-containing compound having at least two terminal groups of formula -NH-CO-CO-NH-R1 -SH where R1 is an alkylene, reaction mixtures containing the thiol-containing compound and an epoxy resin, and compositions containing a polymeri...
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WO/2023/179499A1 |
The present invention relates to the field of gene drug delivery, and particularly to a lipid compound having a glycerol skeleton, a lipid carrier based on the lipid compound, a nucleic acid lipid nanoparticle composition, and a pharmace...
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WO/2023/179497A1 |
The present invention belongs to the field of gene drug delivery, and particularly relates to a lipid compound, a lipid carrier based on the lipid compound, a nucleic acid lipid nanoparticle composition and a pharmaceutical formulation. ...
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WO/2023/176487A1 |
The production method according to the present invention is characterized in that a D-amino acid oxidase used in step 2 in the scheme shown below is a polypeptide selected from the below-mentioned polypeptides (a) to (c). According to th...
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WO/2023/172846A1 |
Provided are compounds of Formula (I):and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
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WO/2023/168484A1 |
Compounds of Formula (A) and methods for use as agricultural chemicals, including herbicides: Formula (A)
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WO/2023/169520A1 |
The use of an arylvinyl α-carbonyl acid ester compound (I) as a photoinitiator in LED photopolymerization and a preparation method therefor, which relate to the field of polymer photocuring, and are provided on the basis of the problems...
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WO/2023/166511A1 |
One or more ionizable lipid(s) and lipid nanoparticles comprising same are provided. Pharmaceutical compositions comprising the lipid nanoparticles encapsulating an active agent are also provided.
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WO/2023/165595A1 |
The present invention relates to a liposome for forming a nanodrug carrier. The liposome can form a nanocomposite that selectively and efficiently delivers a pharmaceutically active molecule, and reduce or minimize treatment-associated t...
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WO/2023/159303A1 |
Provided herein are Myc-Max inhibitory compounds having the structure of Formula I or Formula II and compositions thereof for use in the treatment of cancer. In particular, the Myc- Max inhibitory compounds may be useful for the treatmen...
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WO/2023/164544A2 |
Provided herein, inter alia, novel ionizable cationic lipids, lipid nanoparticles comprising the novel ionizable cationic lipids and methods of using said nanoparticles.
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WO/2023/156429A1 |
The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I). The compound of formula (V), the compound of formula (VI) and the compound of formula (VII...
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WO/2023/156450A1 |
There are disclosed phenethylamine compounds, the use of such compounds in the treatment of diseases associated with a serotonin 5-HT2 receptor, pharmaceutical compositions such as tablet compositions and kits containing the compounds, m...
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WO/2023/147478A2 |
The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventi...
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WO/2023/145981A1 |
The present invention relates to a method for preparing an ester thiol compound by reacting a polyalcohol and a mercaptocarboxylic acid and to an optical resin or optical lens obtained therefrom having superior optical properties.
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WO/2023/144265A1 |
The present invention relates to a granular catalyst for the hydrolysis of amino nitriles and/or amino amides to amino acids or derivatives thereof, a process for the preparation of this catalyst and a method for the preparation of an am...
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WO/2023/136688A1 |
The present invention relates to a novel ionizable lipid containing a biodegradable disulfide bond. The ionizable lipid containing a disulfide bond, according to the present invention, stably delivers an anionic drug when prepared into l...
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WO/2023/130181A1 |
The present disclosure relates to compounds of Formula I that exhibit 5-HT2A receptor agonist activity and low 5HT2B receptor agonist activity or deemed 5HT2B receptor agonist inactivity. In at least some cases, such compounds show selec...
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WO/2023/123566A1 |
Provided is a synthesis method for thiodiethylene bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]. The method comprises: reacting 2,6-di-tert-butylphenol with acrylate and further reacting with 2-chloroethanol to obtain the intermed...
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WO/2023/129584A2 |
The disclosure provides for cysteamine prodrugs, pharmaceutical compositions made thereof, and methods thereof including the treatment of any disease or disorder in a subject that can benefit from one or more of the bioprotective effects...
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WO/2023/127808A1 |
There is still a great amount of damage by pests or the like in production of agricultural crops, horticultural crops, and the like, and the development of novel pest control agents is desired due to factors such as the emergence of pest...
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WO/2023/127807A1 |
In the production of agricultural and horticultural crops, etc., damages caused by pest insects, etc. are still significant, and, therefore, the development of novel pest control agents has been required due to factors such as the emerge...
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WO/2023/126376A2 |
The present invention relates to a new, enhanced process for the manufacture of Cysteamine Bitartrate (I) and of its key intermediate thiazolidine (II). Furthermore, it relates to a new processes for the manufacture of crystalline anhydr...
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WO/2023/120292A1 |
Provided is a method for producing a sulfonamide derivative, the method being characterized by including a step of causing a compound having a nitro group to react with a compound having a thiol group under light irradiation, and forming...
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WO/2023/121964A1 |
The present disclosure describes compositions, preparations, nanoparticles (such as lipid nanoparticles), and/or nanomaterials and methods of their use.
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WO/2023/121753A1 |
The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, ...
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WO/2023/120268A1 |
A photosensitive colored resin composition comprising a colorant, a block copolymer having an acidic group and/or a graft copolymer having an acidic group, an alkali-soluble resin which is a random copolymer having an acidic group, a pho...
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WO/2023/122276A1 |
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the c...
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WO/2023/113086A1 |
The present invention relates to: a salt compound comprising a negative ion having a specific structure represented by chemical formula 1, and a positive ion represented by chemical formula 2; a quencher including the salt compound; and ...
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WO/2023/113085A1 |
The present invention relates to: a photoacid generator having a novel structure including an anion having a particular polar functional group such as a sulfonate group; a photoresist composition comprising same; and a photoresist patter...
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WO/2023/115020A2 |
This disclosure relates to compositions and methods for labeling of thioethers, e.g., S-methyl thioether such as methionine or peptides containing the same. In certain embodiments, this disclosure relates to methods of forming N-(sulfane...
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WO/2023/110270A1 |
The present application is directed to a polythiol compound obtainable independently from a) eugenol, b) gallic acid, c) the adduct of guaiacol and vanillin or d) resveratrol and, respectively, having the general Formula VIA, VIB, VIC or...
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WO/2023/106973A1 |
The invention relates to a group of compounds which can be used as hepatoprotective agents. The invention further relates to a pharmaceutical composition which exhibits hepatoprotective activity and contains an effective amount of a comp...
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WO/2023/100848A1 |
The present invention is an anthraquinone compound represented by formula (1) (in the formula, R1 represents a hydrogen atom, a straight chain or branched chain alkyl group having a carbon count of 1-12, or a straight chain or branched c...
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WO/2023/092242A1 |
The present application includes dendrons of Formula I, compositions comprising these dendrons and uses thereof, in particular for the delivery of agents such as nucleic acids and drugs to cells and subjects. (I) wherein each Repeating G...
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WO/2023/077236A1 |
A method for determining whether an individual with prediabetes, AMIS, type 2 diabetes, gestational diabetes, insulin resistance, or impaired glucose tolerance will respond to a bethanechol and N-acetylcysteine treatment is taught. Blood...
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WO/2023/065802A1 |
The present invention belongs to the field of polythiol compounds and uses thereof, relating in particular to a polythiol compound and a preparation method therefor, a curing agent, a resin composition, an adhesive, and a sealant. The po...
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WO/2023/067059A1 |
The invention provides a process for producing DL-methionine and methionine diketopiperazine (DKP), characterized in that a DKP-containing mother liquor which originates from a process for producing DKP starting from a precursor product ...
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WO/2023/047104A9 |
The invention relates to a process for producing a compound comprising an 18F-difluoromethyl group or a compound comprising an 18F-difluoromethylene group, which process comprises contacting a compound comprising a nucleophilic group wit...
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WO/2023/061999A1 |
The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.
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WO/2023/058449A1 |
Provided are: a naphthalene dithiol capable of achieving both high refractive index and high solubility (compatibility) or a derivative thereof; and a production method and a use for the same. A naphthalene compound according to the pr...
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WO/2023/057545A1 |
A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in a method of therapy, wherein: R1 is selected from: (i) phenyl, optionally substituted by R1a and R1b; (ii) pyridyl; and (iii) naphthyl, optionally subst...
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WO/2023/054952A1 |
The present invention relates to a solventless quantum dot composition, a method for producing same, and a cured film, a color filter, and a display device which comprise same. Specifically, the solventless quantum dot composition accord...
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WO/2023/054417A1 |
Provided as an extraction agent capable of selectively extracting lithium salt is a lithium salt extraction agent which is at least one compound selected from the group consisting of compounds represented by general formula (1) and compo...
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